Superfund Research Program
Modulation of Uranium and Arsenic Immune Dysregulation by Zinc
Project Leader: Debra MacKenzie
Co-Investigators: Laurie G. Hudson, Esther Erdei
Grant Number: P42ES025589
Funding Period: 2017-2022
Project-Specific Links
- Project Summary
Publications
2022
- Cooper KL, Volk L, Dominguez DR, Duran AD, Liu K, Hudson LG. 2022. Contribution of NADPH oxidase to the retention of UVR-induced DNA damage by arsenic. Toxicol Appl Pharmacol 434:115799. doi:10.1016/j.taap.2021.115799 PMID:34798142
- Du R, Li L, Hudson LG, Nozadi S, Lewis JL. 2022. An adjusted partial least squares regression framework to utilize additional exposure information in environmental mixture data analysis. Journal of Applied Statistics doi:10.1080/02664763.2022.2043254
2021
- Nozadi S, Li L, Luo L, MacKenzie D, Erdei E, Du R, Roman C, Hoover J, O'Donald ER, Burnette C, Lewis JL. 2021. Prenatal metal exposures and infants' developmental outcomes in a Navajo population. Int J Environ Res Public Health 19(1):425. doi:10.3390/ijerph19010425 PMID:35010683 PMCID:PMC8744969
- Schilz JR, Dashner-Titus EJ, Luo L, Simmons KA, MacKenzie D, Hudson LG. 2021. Co-exposure of sodium arsenite and uranyl acetate differentially alters gene expression in CD3/CD28 activated CD4+ T-cells. Toxicol Rep 8:1917-1929. doi:10.1016/j.toxrep.2021.11.019
- Shankar P, Dashner-Titus EJ, Truong L, Hayward K, Hudson LG, Tanguay RL. 2021. Developmental toxicity in zebrafish (Danio rerio) exposed to uranium: A comparison with lead, cadmium, and iron. Environ Pollut 269:116097. doi:10.1016/j.envpol.2020.116097 PMID:33246768 PMCID:PMC7785642
- Zhou X, Speer RM, Volk L, Hudson LG, Liu K. 2021. Arsenic co-carcinogenesis: Inhibition of DNA repair and interaction with zinc finger proteins. Semin Cancer Biol 76:86-98. doi:10.1016/j.semcancer.2021.05.009 PMID:33984503 PMCID:PMC8578584
2020
- Dashner-Titus EJ, Schilz JR, Simmons KA, Duncan TR, Alvarez SC, Hudson LG. 2020. Differential response of human T-lymphocytes to arsenic and uranium. Toxicol Lett 333:269-278. doi:10.1016/j.toxlet.2020.08.013 PMID:32866568 PMCID:PMC7590629
- Lin Y, Hoover JH, Beene D, Erdei E, Liu Z. 2020. Environmental risk mapping of potential abandoned uranium mine contamination on the Navajo Nation, USA, using a GIS-based multi-criteria decision analysis approach. Environ Sci Pollut Res Int doi:10.1007/s11356-020-09257-3 PMID:32468361
- Roberts MH, Erdei E. 2020. Comparative United States autoimmune disease rates for 2010-2016 by sex, geographic region, and race. Autoimmun Rev 19(1):102423. doi:10.1016/j.autrev.2019.102423 PMID:31733367 PMCID:PMC6925958
2019
- Luo L, Hudson LG, Lewis JL, Lee J. 2019. Two-step approach for assessing the health effects of environmental chemical mixtures: application to simulated datasets and real data from the Navajo Birth Cohort Study. Environ Health 18(46):doi:10.1186/s12940-019-0482-6 PMID:31072361 PMCID:PMC6507239
2018
- Dashner-Titus EJ, Hoover JH, Li L, Lee J, Du R, Liu K, Traber MG, Ho E, Lewis JL, Hudson LG. 2018. Metal exposure and oxidative stress markers in pregnant Navajo Birth Cohort Study participants. Free Radic Biol Med 124:484-492. doi:10.1016/j.freeradbiomed.2018.04.579 PMID:29723666 PMCID:PMC6381929
- Gonzales M, Erdei E, Hoover JH, Nash J. 2018. A review of environmental epidemiology studies in southwestern and mountain west rural minority populations. Curr Epidemiol Rep 5(2):101-113. doi:10.1007/s40471-018-0146-z PMID:30906685 PMCID:PMC6426134