Superfund Research Program

Research Translation Core

Project Leader: Thomas J. McDonald
Co-Investigator: Weihsueh A. Chiu
Grant Number: P42ES027704
Funding Period: 2017-2022

Project-Specific Links

Publications

2022

• Bhandari S, Casillas GA, Aly NA, Zhu R, Newman G, Wright FA, Miller A, Adler G, Rusyn I, Chiu WA. 2022. Spatial and temporal analysis of impacts of Hurricane Florence on criteria air pollutants and air toxics in eastern North Carolina. Int J Environ Res Public Health 19(3):doi:10.3390/ijerph19031757 PMID:35162780 PMCID:PMC8835244
• Fawkes L, McDonald TJ, Roh T, Chiu WA, Taylor RJ, Sansom G. 2022. A participatory-based research approach for assessing exposure to lead-contaminated drinking water in the Houston neighborhood of the Greater Fifth Ward. Int J Environ Res Public Health 19(13):doi:10.3390/ijerph19138135
• Kirsch KR, McDonald TJ, Newman G, Xu X, Horney JA. 2022. Surveys of community garden affiliates and soils in Houston, Texas. Environ Monit Assess 194:330. doi:10.1007/s10661-022-09997-4 PMID:35384492
• Roman-Hubers AT, Cordova AC, Rohde A, Chiu WA, McDonald TJ, Wright FA, Dodds J, Baker ES, Rusyn I. 2022. Characterization of compositional variability in petroleum substances. Fuel 317:doi:10.1016/j.fuel.2022.123547 PMID:35250041 PMCID:PMC8896784
• Sansom G, Fawkes L, Thompson C, Losa LM, McDonald TJ, Chiu WA. 2022. Cancer risk associated with soil distribution of polycyclic aromatic hydrocarbons within three environmental justice neighborhoods in Houston, Texas. Environ Geochem Health doi:10.1007/s10653-022-01245-5 PMID:35246781
• Stone KW, Felkner M, Garza E, Perez-Patron M, Schmit C, McDonald TJ, Horney JA. 2022. Changes to timeliness and completeness of infectious disease reporting in Texas after implementation of an epidemiologic capacity program. Public Health Rep 137:679-686. doi:10.1177/00333549211009490 PMID:33930278 PMCID:PMC9257493

2021

• Camargo K, Foster M, Buckingham B, McDonald TJ, Chiu WA. 2021. Characterizing baseline legacy chemical contamination in urban estuaries for disaster-research through systematic evidence mapping: A case study. Chemosphere 281:doi:10.1016/j.chemosphere.2021.130925 (ahead of print)
• Camargo K, Vogelbein MA, Horney JA, Dellapenna TM, Knap A, Sericano JL, Wade TL, McDonald TJ, Chiu WA, Unger M. 2021. Biosensor applications in contaminated estuaries: Implications for disaster research response. Environ Res 204:111893. doi:10.1016/j.envres.2021.111893 PMID:34419473 PMCID:PMC8639622
• Casillas GA, Johnson N, Chiu WA, Ramirez J, McDonald TJ, Horney JA. 2021. Polycyclic aromatic hydrocarbons in Houston parks after Hurricane Harvey. Environ Justice 14(4):277-287. doi:10.1089/env.2020.0073 PMID:34484557 PMCID:PMC8404169
• Chen Z, Lloyd D, Zhou Y, Chiu WA, Wright FA, Rusyn I. 2021. Risk characterization of environmental samples using in vitro bioactivity and polycyclic aromatic hydrocarbon (PAH) concentrations data. Toxicol Sci 179(1):108-120. doi:10.1093/toxsci/kfaa166 PMID:33165562 PMCID:PMC7797768
• Fantke P, Chiu WA, Aylward L, Judson RR, Huang L, Jang S, Gouin T, Rhomberg L, Aurisano N, McKone TE, Jolliet O. 2021. Exposure and toxicity characterization of chemical emissions and chemicals in products: Global recommendations and implementation in USEtox. Int J Life Cycle Assess 17:doi:10.1007/s11367-021-01889-y
• Hearon S, Wang M, McDonald TJ, Phillips TD. 2021. Decreased bioavailability of aminomethylphosphonic acid (AMPA) in genetically modified corn with activated carbon or calcium montmorillonite clay inclusion in soil. J Environ Sci (China) 100:131-143. doi:10.1016/j.jes.2020.06.029 PMID:33279026 PMCID:PMC7719843
• Jang S, McDonald TJ, Bhandari S, Rusyn I, Chiu WA. 2021. Spatial and temporal distribution of surface water contaminants in the Houston Ship Channel after the Intercontinental Terminal Company Fire. J Expo Sci Environ Epidemiol 31(5):doi:10.1038/s41370-021-00343-3 PMID:34079063 (ahead of print)
• Luo Y, Chen Z, Blanchette A, Zhou Y, Wright FA, Baker ES, Chiu WA, Rusyn I. 2021. Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-derived cardiomyocytes. Food Chem Toxicol doi:10.1016/j.fct.2021.111979 PMID:33450301
• Roman-Hubers AT, Cordova AC, Aly NA, McDonald TJ, Lloyd D, Wright FA, Baker ES, Chiu WA, Rusyn I. 2021. Data processing workflow to identify structurally related compounds in petroleum substances using ion mobility spectrometry-mass spectrometry. Energy Fuels 35:10529-10539. doi:10.1021/acs.energyfuels.1c00892 PMID:34366560 PMCID:PMC8341389
• Roman-Hubers AT, McDonald TJ, Baker ES, Chiu WA, Rusyn I. 2021. A comparative analysis of analytical techniques for rapid oil spill identification. Environ Toxicol Chem 40(4):1034-1049. doi:10.1002/etc.4961 PMID:33315271 PMCID:PMC8104454
• Stone KW, Felkner M, Garza E, Perez-Patron M, Schmit C, McDonald TJ, Horney JA. 2021. Epidemiology surveillance and capacity improvement: A characterization of Texas, 2017. Disaster Med Public Health Prep 1-8. doi:10.1017/dmp.2020.471 PMID:33726884 (ahead of print)

2020

• Aly NA, Luo Y, Liu Y, Casillas GA, McDonald TJ, Kaihatu JM, Jun M, Ellis N, Gossett S, Dodds J, Baker ES, Bhandari S, Chiu WA, Rusyn I. 2020. Temporal and spatial analysis of per and polyfluoroalkyl substances in surface waters of Houston ship channel following a large-scale industrial fire incident. Environ Pollut 265:115009. doi:10.1016/j.envpol.2020.115009 PMID:32574947 PMCID:PMC7857671
• Bhandari S, Lewis PT, Craft ES, Marvel S, Reif DM, Chiu WA. 2020. HGBEnviroScreen: Enabling community action through data integration in the Houston-Galveston-Brazoria region. Int J Environ Res Public Health 17:doi:10.3390/ijerph17041130 PMID:32053902
• Blessinger T, Davis JA, Chiu WA, Stanek J, Woodall G, Gift J, Thayer KA, Bussard D. 2020. Application of a unified probabilistic framework to the dose-response assessment of acrolein. Environ Int 143:105953. doi:10.1016/j.envint.2020.105953 PMID:32768806 (ahead of print)
• Camargo K, Sericano JL, Bhandari S, Hoelscher C, McDonald TJ, Chiu WA, Wade TL, Dellapenna TM, Liu Y, Knap A. 2020. Polycyclic aromatic hydrocarbon status in post-hurricane Harvey sediments: considerations for environmental sampling in the Galveston Bay/Houston Ship Channel region. Mar Pollut Bull 162:111872. doi:10.1016/j.marpolbul.2020.111872 PMID:33256967 PMCID:PMC7867649
• Chiu WA, Paoli GM. 2020. Recent Advances in Probabilistic Dose-Response Assessment to Inform Risk Based Decision Making. Risk Anal doi:10.1111/risa.13595 PMID:32966629
• Kovalakova P, Cizmas LH, McDonald TJ, Marsalek B, Feng M, Sharma VK. 2020. Occurrence and toxicity of antibiotics in the aquatic environment: A review. Chemosphere 251:126351. doi:10.1016/j.chemosphere.2020.126351 PMID:32443222
• Nickodem CA, Menon R, McDonald TJ, Taylor BD. 2020. Circulating short-chain fatty acids in preterm birth: A pilot case-control study. Reprod Sci 27(5):1181-1186. doi:10.1007/s43032-019-00126-0 PMID:32046422

2019

• Blanchette A, Grimm FA, Dalaijamts C, Hsieh N, Ferguson K, Luo Y, Rusyn I, Chiu WA. 2019. Thorough QT/QTc in a dish: An In Vitro human model that accurately predicts clinical concentration-QTc relationships. Clin Pharmacol Ther 105:1175-1186. doi:10.1002/cpt.1259 PMID:30346629 PMCID:PMC6465173
• Englehardt JD, Chiu WA. 2019. A general dose-response relationship for chronic chemical and other health stressors and mixtures based on an emergent illness severity model. PLoS One 14(2):e0211780. doi:10.1371/journal.pone.0211780 PMID:30768598 PMCID:PMC6377108
• Kvasnicka J, Stylianou KS, Nguyen VK, Huang L, Chiu WA, Burton AG, Semrau J, Jolliet O. 2019. Human Health Benefits from Fish Consumption vs. Risks from Inhalation Exposures Associated with Contaminated Sediment Remediation: Dredging of the Hudson River. Environ Health Perspect 127:doi:10.1289/EHP5034 PMID:31834828
• Lewis L, Borowa-Mazgaj B, de Conti A, Chappell G, Luo Y, Bodnar WM, Konganti K, Wright FA, Threadgill DW, Chiu WA, Pogribny IP, Rusyn I. 2019. Population-based analysis of DNA damage and epigenetic effects of 1,3-butadiene in the mouse. Chem Res Toxicol 32(5):doi:10.1021/acs.chemrestox.9b00035 PMID:30990016 (ahead of print)
• Luo Y, Cichocki JA, Hsieh N, Lewis L, Wright FA, Threadgill DW, Chiu WA, Rusyn I. 2019. Using Collaborative Cross mouse population to fill data gaps in risk assessment: A case study of population-based analysis of toxicokinetics and kidney toxicodynamics of tetrachloroethylene. Environ Health Perspect 127(6):67011. doi:10.1289/EHP5105 PMID:31246107 PMCID:PMC6792382
• Sansom G, Berke P, McDonald TJ, Shipp E, Horney JA. 2019. Evaluating the impact of race and gender on environmental risk perceptions in the Houston neighborhood of Manchester. Environ Justice 12(3):doi:10.1089/env.2018.0028 PMID:31871531 PMCID:PMC6927678
• Sharma VK, Yu X, McDonald TJ, Jinadatha C, Dionysiou DD, Feng M. 2019. Elimination of antibiotic resistance genes and control of horizontal transfer risk by UV-based treatment of drinking water: A mini review. Frontiers of Environmental Science & Engineering 13:37. doi:10.1007/s11783-019-1122-7 PMID:32133212 PMCID:PMC7055709
• Stermer A, Klein D, Wilson S, Dalaijamts C, Bai CY, Hall SJ, Madnick SJ, Bianchi E, Chiu WA, Boekelheide K. 2019. Differential toxicity of water versus gavage exposure to trichloroethylene in rats. Environ Toxicol Pharmacol 68:1-3. doi:10.1016/j.etap.2019.02.003 PMID:30836291 PMCID:PMC6594756
• Stone KW, Casillas GA, Karaye I, Camargo K, McDonald TJ, Horney JA. 2019. Using spatial analysis to examine potential sources of polycyclic aromatic hydrocarbons in an environmental justice community after Hurricane Harvey. Environ Justice 12(4):194-203. doi:10.1089/env.2019.0007 PMID:32292537 PMCID:PMC6707063
• Trueblood A, Ross J, Shipp E, McDonald TJ. 2019. Feasibility of Portable Fingerstick Cholinesterase Testing in Adolescents in South Texas. J Prim Care Community Health 10:doi:10.1177/2150132719838716 PMID:30929548 PMCID:PMC6444767

2018

• Chiu WA, Axelrad DA, Dalaijamts C, Dockins C, Shao K, Shapiro AJ, Paoli GM. 2018. Beyond the RfD: Broad application of a probabilistic approach to improve chemical dose response assessments for noncancer effects. Environ Health Perspect 126(6):067009. doi:10.1289/EHP3368 PMID:29968566 PMCID:PMC6084844
• Chiu WA, Guyton KZ, Martin MT, Reif DM, Rusyn I. 2018. Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups. ALTEX 35(1):51-64. doi:10.14573/altex.1703231 PMID:28738424 PMCID:PMC5783793
• Chiu WA, Rusyn I. 2018. Advancing chemical risk assessment decision-making with population variability data: challenges and opportunities. Mamm Genome 29(1-2):182-189. doi:10.1007/s00335-017-9731-6 PMID:29299621 PMCID:PMC5849521
• Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. 2018. Application of the key characteristics of carcinogens in cancer hazard identification. Carcinogenesis 39(4):614-622. doi:10.1093/carcin/bgy031 PMID:29562322 PMCID:PMC5888955
• Guyton KZ, Rusyn I, Chiu WA, Corpet DE, van den Berg M, Ross MK, Christiani DC, Beland FA, Smith MT. 2018. Re: Application of the key characteristics of carcinogens in cancer hazard evaluation : response to Goodman, Lynch and Rhomberg. Carcinogenesis 39(8):1091-1093. doi:10.1093/carcin/bgy082 PMID:29982359 PMCID:PMC6067125
• Horney JA, Casillas GA, Baker ES, Stone KW, Kirsch KR, Camargo K, Wade TL, McDonald TJ. 2018. Comparing residential contamination in a Houston environmental justice neighborhood before and after Hurricane Harvey. PLoS One 13(2):e0192660. doi:10.1371/journal.pone.0192660 PMID:29420658 PMCID:PMC5805347
• Mendoza-Sanchez I, Autenrieth RL, McDonald TJ, Cunningham JA. 2018. Biological limitations of dechlorination of cis-Dichloroethene during transport in porous media. Environ Sci Technol 52(2):684-691. doi:10.1021/acs.est.7b04426 PMID:29236483 (ahead of print)
• Sansom G, Kirsch KR, Stone KW, McDonald TJ, Horney JA. 2018. Domestic exposures to polycyclic aromatic hydrocarbons in a Houston, Texas, environmental justice neighborhood. Environ Justice 11(5):183-191. doi:10.1089/env.2018.0004 PMID:30464781 PMCID:PMC6241524
• Tolgyesi A, Giri A, Barta E, McDonald TJ, Sharma VK. 2018. Determination of thyreostats in urine using supported liquid extraction and mixed-mode cation-exchange solid-phase extraction: Screening and confirmatory methods. Journal of Chromatographic Science 56(9):858-866. doi:10.1093/chromsci/bmy054 PMID:29878072 PMCID:PMC6454509
• Venkatratnam A, House JS, Konganti K, McKenney C, Threadgill DW, Chiu WA, Aylor DL, Wright FA, Rusyn I. 2018. Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse. Mamm Genome 29:168-181. doi:10.1007/s00335-018-9734-y PMID:29353386 PMCID:PMC6094947
• Wignall JA, Muratov EN, Sedykh A, Guyton KZ, Tropsha A, Rusyn I, Chiu WA. 2018. Conditional toxicity value (CTV) predictor: an in silico approach for generating quantitative risk estimates for chemicals. Environ Health Perspect 126(5):057008. doi:10.1289/EHP2998 PMID:29847084 PMCID:PMC6071978

2017

• Bokkers BG, Mengelers MJ, Bakker MI, Chiu WA, Slob W. 2017. APROBA-Plus: A probabilistic tool to evaluate and express uncertainty in hazard characterization and exposure assessment of substances. Food Chem Toxicol 110:408-417. doi:10.1016/j.fct.2017.10.038 PMID:29074418 PMCID:PMC5793872
• Cichocki JA, Furuya S, Venkatratnam A, McDonald TJ, Knap A, Wade TL, Sweet S, Chiu WA, Threadgill DW, Rusyn I. 2017. Characterization of variability in toxicokinetics and toxicodynamics of tetrachloroethylene using the collaborative cross mouse population. Environ Health Perspect 125(5):057006. doi:10.1289/ehp788 PMID:28572074 PMCID:PMC5726344
• Grimm FA, Russell WK, Luo Y, Iwata Y, Chiu WA, Roy T, Boogaard PJ, Ketelslegers HB, Rusyn I. 2017. Grouping of petroleum substances as example UVCBs by ion mobility-mass spectrometry to enable chemical composition-based read-across. Environ Sci Technol 51:7197-7207. doi:10.1021/acs.est.6b06413 PMID:28502166 PMCID:PMC5627358
• Sharma VK, McDonald TJ, Sohn M, Anquandah GA, Pettine M, Zboril R. 2017. Assessment of toxicity of selenium and cadmium selenium quantum dots: A review. Chemosphere 188:403-413. doi:10.1016/j.chemosphere.2017.08.130 PMID:28892773
• Sharma VK, Yang X, Cizmas LH, McDonald TJ, Luque R, Sayes CM, Yuan B, Dionysiou DD. 2017. Impact of metal ions, metal oxides, and nanoparticles on the formation of disinfection byproducts during chlorination. Chem Eng J 317:777-792. doi:10.1016/j.cej.2017.02.071
• Sirenko O, Grimm FA, Ryan KR, Iwata Y, Chiu WA, Parham F, Wignall JA, Anson B, Cromwell EF, Behl M, Rusyn I, Tice RR. 2017. In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model. Toxicol Appl Pharmacol 322:60-74. doi:10.1016/j.taap.2017.02.020 PMID:28259702 PMCID:PMC5734940
• Telesford-Checkley J, Mora MA, Gentry TJ, McDonald TJ, Boellstorff DE. 2017. Impacts of heronries on water quality as evaluated through Escherichia coli and fecal sterol analyses. Water Environ Res 89(6):508-518. doi:10.2175/106143017X14902968254430 PMID:28545602
• Venkatratnam A, Furuya S, Kosyk O, Gold A, Bodnar WM, Konganti K, Threadgill DW, Gillespie DA, Aylor DL, Wright FA, Chiu WA, Rusyn I. 2017. Editor's Highlight: Collaborative Cross mouse population enables refinements to characterization of the variability in toxicokinetics of trichloroethylene and provides genetic evidence for the role of PPAR pathway in its oxidative metabolism. Toxicol Sci 158(1):48-62. doi:10.1093/toxsci/kfx065 PMID:28369613
• Zhou Y, Cichocki JA, Soldatow VY, Scholl EH, Gallins P, Jima DD, Yoo HS, Chiu WA, Wright FA, Rusyn I. 2017. Editor's highlight: comparative dose-response analysis of liver and kidney transcriptomic effects of trichloroethylene and tetrachloroethylene in B6C3F1 mouse. Toxicol Sci 160(1):95-110. doi:10.1093/toxsci/kfx165 PMID:28973375 PMCID:PMC5837274