Superfund Research Program
Critical Effects Associated with Developmental PFAS Exposure Profiles
Project Leader: Philippe Grandjean
Grant Number: P42ES027706
Funding Period: 2022-2027
Project-Specific Links
- Project Summary
Publications
2024
- Andersen HR, Grandjean P, Main K, Jensen TK, Nielsen F. 2024. Higher serum concentrations of PFAS among pesticide exposed female greenhouse workers. Int J Hyg Environ Health 255:doi:10.1016/j.ijheh.2023.114292 PMID:37952389
- Nielsen F, Fischer FC, Leth P, Grandjean P. 2024. Occurrence of major perfluorinated alkylate substances in human blood and target organs. Environ Sci Technol 58(1):143-149. doi:10.1021/acs.est.3c06499 PMID:38154793 PMCID:10785751
- Sigvaldsen A, Højsager F, Paarup H, Beck I, Timmermann CA, Boye H, Nielsen F, Halldorsson T, Nielsen C, Möller S, Barington T, Grandjean P, Jensen TK. 2024. Early-life exposure to perfluoroalkyl substances and serum antibody concentrations towards common childhood vaccines in 18-month-old children in the Odense Child Cohort. Environ Res 242:117814. doi:10.1016/j.envres.2023.117814 PMID:38042520
2023
- Baumert BO, Fischer FC, Nielsen F, Grandjean P, Bartell SM, Stratakis N, Walker DI, Valvi D, Kohli R, Inge T, Ryder J, Jenkins T, Sisley S, Xanthakos S, Rock S, La Merrill MA, Conti D, McConnell R, Chatzi L. 2023. Paired liver:plasma PFAS concentration ratios from adolescents in the Teen-LABS Study and derivation of empirical and mass balance models to predict and explain liver PFAS accumulation. Environ Sci Technol 57(40):14817-14826. doi:10.1021/acs.est.3c02765 PMID:37756184 PMCID:PMC10591710
- Beck I, Bilenberg N, Möller S, Nielsen F, Grandjean P, Højsager F, Halldorsson T, Nielsen C, Jensen TK. 2023. Association between prenatal and early postnatal exposure to perfluoroalkyl substances and IQ score in 7-year-old children from the Odense Child Cohort. Am J Epidemiol 192(9):1522-1535. doi:10.1093/aje/kwad110 PMID:37119029
- Budtz-Jorgensen E, Grandjean P. 2023. Benchmark dose calculations for PFAS exposure based on two data sets on immunotoxic effects. Environ Health 22(1):40. doi:10.1186/s12940-023-00985-w PMID:37147704 PMCID:10163703
- Grandjean P, Meddis A, Nielsen F, Beck IH, Bilenberg N, Goodman C, Hu H, Till C, Budtz-Jorgensen E. 2023. Dose dependence of prenatal fluoride exposure associations with cognitive performance at school age in three prospective studies. Eur J Public Health doi:10.1093/eurpub/ckad170 PMID:37798092
- Grandjean P, Meddis A, Nielsen F, Sjodin A, Hjorth MF, Astrup A, Budtz-Jorgensen E. 2023. Weight loss relapse associated with exposure to perfluoroalkylate substances. Obesity (Silver Spring) doi:10.1002/oby.23755 PMID:37069729 PMCID:PMC5810983
- Grandjean P, Shih Y, Jorgensen LH, Nielsen F, Weihe P, Budtz-Jorgensen E. 2023. Estimated exposure to perfluoroalkyl substances during infancy and serum-adipokine concentrations in later childhood. Pediatric Research 94(5):1832-1837. doi:10.1038/s41390-023-02665-4 PMID:37316707 PMCID:10624607
- Sorensen M, Fisker A, Dalgard C, Jensen KJ, Nielsen F, Benn CS, Grandjean P, Timmermann A. 2023. Predictors of serum- per- and polyfluoroalkyl substance (PFAS) concentrations among infants in Guinea-Bissau, West Africa. Environ Res 228:115784. doi:10.1016/j.envres.2023.115784 PMID:37011795
- Valvi D, Christiani DC, Coull BA, Hojlund K, Nielsen F, Audouze K, Su L, Grandjean P. 2023. Gene-environment interactions in the associations of PFAS exposure with insulin sensitivity and beta-cell function in a Faroese cohort followed from birth to adulthood. Environ Res 226:115600. doi:10.1016/j.envres.2023.115600 PMID:36868448 PMCID:PMC1010192
2022
- Blomberg AJ, Mortensen J, Weihe P, Grandjean P. 2022. Bone mass density following developmental exposures to perfluoroalkyl substances (PFAS): a longitudinal cohort study. Environmental Health 21(1):113. doi:10.1186/s12940-022-00929-w PMID:36402982 PMCID:PMC9675242