Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Program Publications: Baylor College of Medicine: Polycyclic Aromatic Hydrocarbons: Ultrasensitive Detection, Early-Life Exposures - Clinical Outcomes (Preterm Births, Chronic Lung Disease, and Neurocognitive Deficits), Prevention and Remediation

Superfund Research Program

Polycyclic Aromatic Hydrocarbons: Ultrasensitive Detection, Early-Life Exposures - Clinical Outcomes (Preterm Births, Chronic Lung Disease, and Neurocognitive Deficits), Prevention and Remediation

Center Director: Bhagavatula Moorthy
Grant Number: P42ES027725
Funding Period: 2020-2025
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

Publications

2021

2020

  • Antony K, Romezi M, Lindgren K, Mitchell KB, Venable SF, Racusin DA, Suter MA, Aagaard KM. 2020. Maternal Metabolic Biomarkers are Associated with Obesity and Excess Gestational Weight Gain. Am J Perinatol doi:10.1055/s-0040-1708855 PMID:32232816
  • Banerjee S, Suter MA, Aagaard KM. 2020. Interactions between environmental exposures and the microbiome: Implications for fetal programming. Curr Opin Endocr Metab Res 13:39-48. doi:10.1016/j.coemr.2020.09.003 PMID:33283070 PMCID:PMC771673
  • Callaway DA, Jiang W, Wang L, Lingappan K, Moorthy B. 2020. Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-inducer, beta-naphthoflavone (BNF), and differential sex-specific effects. Free Radic Biol Med 160:208-218. doi:10.1016/j.freeradbiomed.2020.07.027 PMID:32791187 PMCID:PMC7704914
  • Coarfa C, Grimm SL, Katz T, Zhang Y, Jangid RK, Walker C, Moorthy B, Lingappan K. 2020. Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. Redox Biol 37:101718. doi:10.1016/j.redox.2020.101718 PMID:32961439 PMCID:PMC7509469
  • Eaves LA, Nguyen HT, Rager JE, Sexton K, Howard T, Smeester L, Freedman AN, Aagaard KM, Shope C, Lefer B, Flynn JH, Erickson MH, Fry RC, Vizuete W. 2020. Identifying the transcriptional response of cancer and inflammation-related genes in lung cells in relation to ambient air chemical mixtures in Houston, Texas. Environ Sci Technol 54:13807-13816. doi:10.1021/acs.est.0c02250 PMID:33064461 PMCID:PMC7757424
  • Flores-Villanueva P, Sobhani N, Wang X, Li Y. 2020. MR1-restricted T Cells in cancer immunotherapy. Cancers (Basel) 12:doi:10.3390/cancers12082145 PMID:32756356
  • Gastelum G, Jiang W, Wang L, Zhou G, Borkar R, Putluri N, Moorthy B. 2020. Polycyclic aromatic hydrocarbon-induced pulmonary carcinogenesis in cytochrome P450 (CYP)1A1-and 1A2-null mice: roles of CYP1A1 and CYP1A2. Toxicol Sci 177:347-361. doi:10.1093/toxsci/kfaa107 PMID:32726451
  • Gu G, Tian L, Herzog SK, Rechoum Y, Gelsomino L, Gao M, Du L, Kim J, Dustin D, Lo H, Beyer AR, Edwards DG, Gonzalez T, Tsimelzon A, Huang HJ, Fernandez NM, Grimm SL, Hilsenbeck SG, Liu D, Xu J, Alaniz A, Li S, Mills GB, Janku F, Kittler R, Zhang XH, Coarfa C, Foulds CE, Symmans W, Ando S, Fuqua SA. 2020. Hormonal modulation of ESR1 mutant metastasis. Oncogene doi:10.1038/s41388-020-01563-x PMID:33323970 (ahead of print)
  • Liu M, Wang X, Li W, Yu X, Flores-Villanueva P, Xu-Monette ZY, Li L, Zhang M, Young KH, Ma X, Li Y. 2020. Targeting PD-L1 in non-small cell lung cancer using CAR T cells. Oncogenesis 9:72. doi:10.1038/s41389-020-00257-z PMID:32792499 PMCID:PMC7426958
  • Preidis GA, Soni KG, Suh J, Halder T, Kim K, Choi J, Li F, Devaraj S, Connor ME, Coarfa C, Jung SY, Moore DD. 2020. Coagulopathy in Malnourished Mice is Sexually Dimorphic and Regulated by Nutrient-sensing Nuclear Receptors. Hepatol Commun 4:1835-1850. doi:10.1002/hep4.1622 PMID:33305154 PMCID:PMC7706303
  • Stading R, Chu C, Couroucli XI, Lingappan K, Moorthy B. 2020. Molecular role of cytochrome P4501A enzymes in oxidative stress. Curr Opin Toxicol 20-21:77-84. doi:10.1016/j.cotox.2020.07.001 PMID:33283080 PMCID:PMC7709944
  • Stading R, Couroucli XI, Lingappan K, Moorthy B. 2020. The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury. Expert Opin Drug Metab Toxicol 8:doi:10.1080/17425255.2021.1853705 PMID:33215946
  • Tao G, Huang J, Moorthy B, Wang C, Hu M, Gao S, Ghose R. 2020. Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and hepatotoxicity. Expert Opin Drug Metab Toxicol 16:doi:10.1080/17425255.2020.1815705 PMID:32841068

2019

  • Hassanin AA, Tavera-Garcia MA, Moorthy B, Zhou GD, Ramos KS. 2019. Lung genotoxicity of benzo(a)pyrene in vivo involves reactivation of LINE-1 retrotransposon and early reprogramming of oncogenic regulatory networks. Am J Physiol Lung Cell Mol Physiol 317:doi:10.1152/ajplung.00304.2019 (accepted for publication)
  • Suter MA, Aagaard KM, Coarfa C, Robertson M, Zhou GD, Jackson BP, Thompson D, Putluri V, Putluri N, Hagan J, Wang L, Jiang W, Lingappan K, Moorthy B. 2019. Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB). Biochem Biophys Res Commun 516(2):344-349. doi:10.1016/j.bbrc.2019.06.049 PMID:31208719 PMCID:PMC6637943
Back
to Top