Superfund Research Program
Uncovering the Mechanisms of PFAS-Induced Immunotoxicity: An Important Public Health Endpoint
Project Leader: Seth W. Kullman
Co-Investigators: Jamie C. DeWitt (Oregon State University), Jeffrey Yoder
Grant Number: P42ES031009
Funding Period: 2020-2025
Project-Specific Links
- Project Summary
Publications
2023
- Cuffney M, Wilkie AA, Kotlarz N, Knappe D, Lea CS, Collier D, DeWitt JC, Hoppin JA. 2023. Factors associated with per- and polyfluoroalkyl substances (PFAS) serum concentrations in residents of New Hanover County, North Carolina: The GenX exposure study. Environ Res 237:117020. doi:10.1016/j.envres.2023.117020 PMID:37673120
- Efromson J, Ferrero G, Begue A, Doman TJ, Dugo C, Barker A, Saliu V, Reamey P, Kim K, Harfouche M, Yoder J. 2023. Automated, high-throughput quantification of EGFP-expressing neutrophils in zebrafish by machine learning and a highly-parallelized microscope. PLoS One 18(12):e0295711. doi:10.1371/journal.pone.0295711 PMID:38060605 PMCID:PMC10703246
- Phelps D, Palekar AI, Conley HE, Ferrero G, Driggers JH, Linder KE, Kullman SW, Reif DM, Sheats MK, DeWitt JC, Yoder J. 2023. Legacy and emerging per- and polyfluoroalkyl substances suppress the neutrophil respiratory burst. J Immunotoxicol 20(1):2176953. doi:10.1080/1547691X.2023.2176953 PMID:36788734 PMCID:PMC10361455
- Taylor KD, Woodlief TL, Ahmed A, Hu Q, Duncker PC. 2023. Quantifying the impact of PFOA exposure on B cell development and antibody production. Toxicol Sci doi:10.1093/toxsci/kfad043 PMID:37162486 PMCID:PMC10306397
- Wallis DJ, Kotlarz N, Knappe D, Collier D, Lea CS, Reif DM, McCord JP, Strynar M, DeWitt JC, Hoppin JA. 2023. Estimation of the half-lives of recently detected per- and polyfluorinated alkyl ethers in an exposed community. Environ Sci Technol 57(41):15348-15355. doi:10.1021/acs.est.2c08241 PMID:37801709
2022
- Ducatman A, LaPier J, Fuoco RE, DeWitt JC. 2022. Official health communications are failing PFAS-contaminated communities. Environmental Health doi:10.1186/s12940-022-00857-9 PMID:35538533 PMCID:PMC9092686
- McDonough CA, Li W, Bischel HN, De Silva AO, DeWitt JC. 2022. Widening the lens on PFASs: Direct human exposure to perfluoroalkyl acid precursors (pre-PFAAs). Environ Sci Technol 56(10):6004-6013. doi:10.1021/acs.est.2c00254 PMID:35324171