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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Research Briefs: University of Washington

Superfund Research Program

Cellular and Molecular Mechanisms of Cadmium Neurotoxicity

Project Leader: Zhengui Xia
Co-Investigators: Daniel Storm, Evan P. Gallagher
Grant Number: P42ES004696
Funding Period: 2015-2023
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Research Briefs

  • 301 - Cadmium Exposure Impairs Production of Neurons Responsible for Learning and Memory -- Xia
    Release Date: 01/08/2020

    A new study funded by the Superfund Research Program (SRP) shows cadmium exposure can impair new neurons from forming and maturing in the hippocampus region of the brain. Led by Zhengui Xia, Ph.D., the researchers at the University of Washington (UW) SRP Center also found that cadmium can lead to the death of stem cells that produce these neurons. In people, learning and memory formation depends on the production of new neurons in this region of the brain.

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Last Reviewed: April 09, 2025