Superfund Research Program
Molecular and Microbial Mechanisms Leading to Triclosan Induced Liver Fibrosis
Project Leader: Robert H. Tukey
Grant Number: P42ES010337
Funding Period: 2017-2023
Project-Specific Links
- Project Summary
Research Briefs
- 314 - Triclosan and a High-fat Diet Worsen Liver Disease in Mice -- Tukey
Release Date: 02/03/2021A new study funded by the NIEHS Superfund Research Program (SRP) shows triclosan exposure, in combination with a high-fat diet, can worsen nonalcoholic fatty liver disease. Led by Robert Tukey, Ph.D., researchers at the University of California San Diego SRP Center described the molecular mechanisms by which triclosan alters metabolism and gut microbiota, resulting in fat buildup in the liver.