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Your Environment. Your Health.

Research Briefs: Duke University

Superfund Research Program

Mechanisms and Consequences of Evolved Adaptation to Environmental Pollution

Project Leader: Richard T. Di Giulio
Co-Investigator: David E. Hinton
Grant Number: P42ES010356
Funding Period: 2011-2022

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Research Briefs

  • 302 - PAH and Hypoxia Exposure Result in Mitochondrial Dysfunction in Fish -- Di Giulio
    Release Date: 02/05/2020

    Zebrafish exposed to polycyclic aromatic hydrocarbons (PAHs) in water with inadequate oxygen, or hypoxia, can experience a broad range of effects on the mitochondria, according to an NIEHS Superfund Research Program (SRP)-funded study. Changes to the function and integrity of mitochondria, which are organelles that make energy for the cell, can disrupt metabolism and reduce organism fitness and performance.

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Last Reviewed: December 05, 2024