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Research Briefs: Duke University

Superfund Research Program

Thyroid Metabolism Disruption Key in Toxicant-Induced Developmental Impairment

Project Leader: Heather M. Stapleton
Co-Investigator: P. Lee Ferguson
Grant Number: P42ES010356
Funding Period: 2011-2017
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Research Briefs

  • 237 - The Flame Retardant Firemaster 550, Fat Cells, and Bone Health -- Schlezinger
    Release Date: 09/03/2014

    Researchers from the Boston University (BU) and Duke University Superfund Research Program (SRP) Centers found that components of the flame-retardant mixture Firemaster® 550 (FM550) may stimulate growth of fat cells and reduce bone health. The results of the collaborative study suggest that triphenyl phosphate (TPP), a component of FM550 that is widespread in household products and house dust, interacts with a protein that regulates fat cell differentiation and lipid storage.

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