Superfund Research Program
Thyroid Metabolism Disruption Key in Toxicant-Induced Developmental Impairment
- Project Summary
- 237 - The Flame Retardant Firemaster 550, Fat Cells, and Bone Health -- Schlezinger
Release Date: 09/03/2014
Researchers from the Boston University (BU) and Duke University Superfund Research Program (SRP) Centers found that components of the flame-retardant mixture Firemaster® 550 (FM550) may stimulate growth of fat cells and reduce bone health. The results of the collaborative study suggest that triphenyl phosphate (TPP), a component of FM550 that is widespread in household products and house dust, interacts with a protein that regulates fat cell differentiation and lipid storage.