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Your Environment. Your Health.

Massachusetts Institute of Technology: Dataset Details, ID=doi: 10.15490/FAIRDOMHUB.1.STUDY.834.4

Superfund Research Program

NDMA and DNA Alkylation Repair in the Liver: Impact of Gene-Environment Interactions on Cellular Responses, Mutations and Cancer

Project Leader: Bevin P. Engelward
Co-Investigator: Leona D. Samson
Grant Number: P42ES027707
Funding Period: 2017-2022
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

Project-Specific Links

Title: Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

Accession Number: doi: 10.15490/FAIRDOMHUB.1.STUDY.834.4

Link to Dataset: https://fairdomhub.org/studies/834

Repository: FAIRDOMHub

Data Type(s): Underlying data from publication

Summary: Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

Publication(s) associated with this dataset:
  • Kay J, Corrigan JJ, Armijo AL, Nazari IS, Kohale I, Torous DK, Avlasevich SL, Croy RG, Wadduwage DN, Carrasco SE, Dertinger SD, White FM, Essigmann JM, Samson LD, Engelward BP. 2021. Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice. Cell Rep 34(11):108864. doi:10.1016/j.celrep.2021.108864 PMID:33730582
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