Superfund Research Program

Genomics and Analytical Chemistry

Project Leader: Daniel K. Nomura
Co-Investigator: Martyn T. Smith
Grant Number: P42ES004705
Funding Period: 2006-2017

Project-Specific Links

Publications

2016

• Counihan JL, Ford B, Nomura DK. 2016. Mapping proteome-wide interactions of reactive chemicals using chemoproteomic platforms. Curr Opin Chem Biol 30:68-76. doi:10.1016/j.cbpa.2015.11.007 PMID:26647369 PMCID:PMC4731263

2015

• Medina-Cleghorn D, Bateman LA, Ford B, Heslin A, Fisher KJ, Dalvie ED, Nomura DK. 2015. Mapping proteome-wide targets of environmental chemicals using reactivity-based chemoproteomic platforms. Chem Biol 22(10):1394-1405. doi:10.1016/j.chembiol.2015.09.008 PMID:26496688 PMCID:PMC4621755

2014

• Medina-Cleghorn D, Heslin A, Morris PJ, Mulvihill MM, Nomura DK. 2014. Multidimensional profiling platforms reveal metabolic dysregulation caused by organophosphorus pesticides. ACS Chem Biol 9(2):423-432. doi:10.1021/cb400796c PMID:24205821 PMCID:PMC4042408
• Medina-Cleghorn D, Nomura DK. 2014. Exploring metabolic pathways and regulation through functional chemoproteomic and metabolomic platforms. Chem Biol 21(9):1171-1184. doi:10.1016/j.chembiol.2014.07.007 PMID:25237861 PMCID:PMC4171689
• Morris PJ, Medina-Cleghorn D, Heslin A, King SM, Orr J, Mulvihill MM, Krauss RM, Nomura DK. 2014. Organophosphorus flame retardants inhibit specific liver carboxylesterases and cause serum hypertriglyceridemia. ACS Chem Biol 9(5):1097-1103. doi:10.1021/cb500014r PMID:24597639 PMCID:PMC4027947

2011

• McHale CM, Zhang L, Lan Q, Vermeulen R, Li G, Hubbard AE, Porter KE, Thomas R, Portier CJ, Shen M, Rappaport SM, Yin S, Rothman N, Smith MT. 2011. Global gene expression profiling of a population exposed to a range of benzene levels. Environ Health Perspect 119:628-634. doi:10.1289/ehp.1002546 PMID:21147609 PMCID:PMC3094412
• Smith MT, Zhang L, McHale CM, Skibola CF, Rappaport SM. 2011. Benzene, the exposome and future investigations of leukemia etiology. Chem Biol Interact 192(1-2):155-159. doi:10.1016/j.cbi.2011.02.010 PMID:21333640 PMCID:PMC3461963

2010

• Vlaanderan J, Moore LE, Smith MT, Lan Q, Zhang L, Skibola CF, Rothman N, Vermeulen R. 2010. Application of OMICS technologies in occupational and environmental health research; current status and projections. Occup Environ Med 67(2):136-143. doi:10.1136/oem.2008.042788 PMID:19933307 PMCID:PMC2910417

2009

• Scelo G, Metayer C, Zhang L, Wiemels JL, Aldrich MC, Selvin S, Month S, Smith MT, Buffler PA. 2009. Household exposure to paint and petroleum solvents, chromosomal translocations, and the risk of childhood leukemia. Environ Health Perspect 117(1):133-139. PMID:19165400

2008

• Wiemels JL, Hofmann J, Kang M, Selzer R, Green R, Zhou M, Zhong S, Zhang L, Smith MT, Marsit CJ, Loh ML, Buffler PA, Yeh R. 2008. Chromosome 12p deletions in TEL-AML1 childhood acute lymphoblastic leukemia are associated with retrotransposon elements and occur postnatally. Cancer Res 68(23):9935-9944. doi:10.1158/0008-5472.CAN-08-2139 PMID:19047175 PMCID:PMC2597307
• Woodruff TJ, Zeise L, Axelrad DA, Guyton KZ, Jannsen S, Miller M, Miller GG, Schwartz J, Alexeef G, Anderson H, Birnbaum LS, Bois FY, Cogliano VJ, Crofton K, Euling SY, Foster PM, Germolec DR, Gray EL, Hattis D, Kyle AD, Luebke RW, Luster MI, Portier CJ, Rice DC, Solomon G, Vandenberg J, Zoeller RT. 2008. Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making. Environ Health Perspect 116(11):1568-1575. doi:10.1289/ehp.11516 PMID:19057713 PMCID:PMC2592280