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Your Environment. Your Health.

Research Briefs: Duke University

Superfund Research Program

Duke University Superfund Research Center - Developmental Co-Exposures: Mechanisms, Outcomes, and Remediation

Center Director: Heather M. Stapleton
Grant Number: P42ES010356
Funding Period: 2000-2027
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Research Briefs

  • 363 - Using a New Model to Identify Health-Impacting Metal Mixtures -- Jayasundara
    Release Date: 03/12/2025

    Researchers funded by the NIEHS Superfund Research Program (SRP) developed the linear mixed-effects model (LMM), a framework for statistical analysis, to quickly and effectively estimate the effects of individual metals and metal mixtures on zebrafish larvae behaviors.

  • 328 - Sampling Device May Predict Methylmercury Accumulation in Wetlands -- Hsu-Kim
    Release Date: 04/06/2022

    NIEHS Superfund Research Program (SRP)-funded researchers, led by Heileen Hsu-Kim, Ph.D., of the Duke University SRP Center, showed that a small plastic sampling device can efficiently predict the potential for methylmercury — an environmental contaminant — to form in freshwater wetlands and to accumulate in organisms living there.

  • 308 - Using Fungi to Clean up Contaminated Soil -- Gunsch
    Release Date: 08/05/2020

    Native fungal communities point to a new way of cleaning up contaminated soil. After conducting a study to characterize fungi found in soil contaminated with polycyclic aromatic hydrocarbons (PAHs), researchers at the NIEHS-funded Superfund Research Program at Duke University discovered a group of fungi that may be promising for remediation.

  • 302 - PAH and Hypoxia Exposure Result in Mitochondrial Dysfunction in Fish -- Di Giulio
    Release Date: 02/05/2020

    Zebrafish exposed to polycyclic aromatic hydrocarbons (PAHs) in water with inadequate oxygen, or hypoxia, can experience a broad range of effects on the mitochondria, according to an NIEHS Superfund Research Program (SRP)-funded study. Changes to the function and integrity of mitochondria, which are organelles that make energy for the cell, can disrupt metabolism and reduce organism fitness and performance.

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Last Reviewed: April 09, 2025