Superfund Research Program
Environmentally Persistent Free Radicals
Center Director: Stephania A. Cormier
Grant Number: P42ES013648
Funding Period: 2009-2018 and 2020-2025
- 289 - Study Sheds Light on Respiratory Toxicity of EPFRs -- Dugas, Cormier
Release Date: 01/30/2019
A new SRP study explains how particulate matter (PM) containing environmentally persistent free radicals (EPFRs) activate the aryl hydrocarbon receptor (AhR). AhR is known to play an important role in detecting and responding to a variety of pollutants. These findings could prove useful in understanding the underlying mechanism of diseases known to be associated with inhalation of PM, such as cardiovascular disease.
- 226 - Environmentally Persistent Free Radicals and Their Lifetime in Ambient Fine Particulate Matter -- Dellinger, Gehling
Release Date: 10/21/2013
For the first time, an expansive study into the concentration and extended decay behaviors of environmentally persistent free radicals (EPFRs) in ambient fine particulate matter revealed the ways in which EPFRs decompose in the environment. EPFRs can cause cell damage and induce an inflammatory response which can lead to a wide range of biological damage.