Title: Chain A, Crystal Structure Of Human Soluble Epoxide Hydrolase Complexed With 1- (1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea

Accession Number: 4OCZ

Link to Dataset: https://www.ncbi.nlm.nih.gov/protein?term=4OCZ[Accession]

Repository: Protein Data Bank (PDB)

Data Type(s): Protein Structure

Experiment Type(s): X-Ray diffraction

Organism(s): Homo sapiens

Summary: Chain A, Crystal Structure Of Human Soluble Epoxide Hydrolase Complexed With 1- (1-isobutyrylpiperidin-4-yl)-3-(4-(trifluoromethyl)phenyl)urea

Publication(s) associated with this dataset:

• Lee KS, Liu J, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. 2014. Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J Med Chem 57(16):7016-7030. doi:10.1021/jm500694p PMID:25079952 PMCID:PMC4148150