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Your Environment. Your Health.

Person Details

Superfund Research Program

Bruce D. Hammock

University of California-Davis
Department of Entomology
90 Briggs Hall
One Shields Avenue
Davis, CA 95616
Phone: 530-752-7519
Fax: 530-752-1537
Email: bdhammock@ucdavis.edu

Projects

Research Briefs

Patents

Hazardous Waste Sites

Frontier Fertilizer

  • University of California-Davis: Immunoassays for Human and Environmental Monitoring

Sulphur Bank Mercury Mine

  • University of California-Davis: Immunoassays for Human and Environmental Monitoring

Publications

2016

2015

2014

2013

  • Bettaieb A, Nagata N, AbouBechara D, Chahed S, Morisseau C, Hammock BD, Haj FG. 2013. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. Journal of Biological Chemistry288:14189-14199. doi:10.1074/jbc.M113.458414
  • Chen T, Takrouri K, Hee-Hwang S, Rana S, Yefidoff-Freedman R, Halperin J, Natarajan A, Morisseau C, Hammock BD, Chorev M, Aktas BH. 2013. Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase. J Med Chem56(23):9457-9470. doi:10.1021/jm400793v
  • Falck D, Schebb N, Prihatiningtyas S, Zhang J, Heus F, Morisseau C, Kool J, Hammock BD, Niessen WM. 2013. Development of on-line liquid chromatography-biochemical detection for soluble epoxide hydrolase inhibitors in mixtures. Chromatographia 76:13-21. doi:10.1007/s10337-012-2343-0
  • Frolov A, Dong H, Jiang M, Yang L, Cook EC, Matnani R, Hammock BD, Crofford LJ. 2013. Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis. Journal of Biological Chemistry288:23696-23703. doi:10.1074/jbc.M112.445916
  • Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ. 2013. Anti-inflammatory properties of prostaglandin E2: Deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice. Prostaglandins, Leukotrienes and Essential Fatty Acids 89(5):351-358. doi:10.1016/j.plefa.2013.08.003
  • Gardell AM, Yang J, Sacchi R, Fangue NA, Hammock BD, Kültz D. 2013. Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis. Journal of Experimental Biology 216(24):4615-4625.
  • Guedes AP, Morisseau C, Sole A, Soares JN, Ulu A, Dong H, Hammock BD. 2013. Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis. Vet Anaesth Analg 40(4):440-448. doi:10.1111/vaa.12030
  • Han J, Kim H, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM. 2013. Photonic crystal lab-on-a-chip for detecting staphylococcal entertoxin B at low attomolar concentration. Anal Chem85(6):3104-3109. doi:10.1021/ac303016h
  • Han J, Kim H, Sudheendra L, Hass EA, Gee SJ, Hammock BD, Kennedy IM. 2013. Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay. Biosens Bioelectron41:302-308. doi:10.1016/j.bios.2012.08.042 PMID:23021853 PMCID:PMC3525773
  • Hwang SH, Wecksler AT, Wagner KM, Hammock BD. 2013. Rationally designed multitarget agents against inflammation and pain. Curr Med Chem 20(13):1783-1799. doi:10.2174/0929867311320130013
  • Hwang SH, Wecksler AT, Zhang G, Morisseau C, Nguyen LV, Fu SH, Hammock BD. 2013. Synthesis and biological evaluation of sorafenib- and regorafenib- like sEH inhibitors. Bioorg Med Chem Lett 23(13):3732-3737. doi:10.1016/j.bmcl.2013.05.011
  • Inceoglu B, Zolkowska D, Yoo H, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. 2013. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS One8(12):doi:10.1371/journal.pone.0080922
  • Kamita SG, Oshita GH, Wang P, Morisseau C, Hammock BD, Nandety R, Falk BW. 2013. Characterization of HOVI-MEH1, a microsomal epoxide hydrolase from the Glassy-Winged Sharpshooter Homalodisca vitripennis. Arch Insect Biochem Physiol 83(4):171-179. doi:10.1002/arch.21100
  • Kamita SG, Yamamoto K, Dadala MM, Pha K, Morisseau C, Escaich A, Hammock BD. 2013. Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens. Insect Biochem Mol Biol 43(3):219-228. doi:10.1016/j.ibmb.2012.12.002
  • Lee E, Kim Y, Lee YT, Hammock BD, Lee H. 2013. Competitive immunochromatographic assay for the detection of the organophosphorus pesticide EPN. Food & Agricultural Immunology24(2):129-138. doi:10.1080/09540105.2012.661703 PMCID:PMC3927651
  • Lee KS, Morisseau C, Yang J, Wang P, Hwang SH, Hammock BD. 2013. Forster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase. Anal Biochem434(2):259-268. doi:10.1016/j.ab.2012.11.015
  • Liu J, Lin Y, Qiu H, Morisseau C, Rose TE, Hwang SH, Chiamvimonvat N, Hammock BD. 2013. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. European Journal of Pharmaceutical Sciences 48(4-5):619-627. doi:10.1016/j.ejps.2012.12.013
  • Morisseau C, Hammock BD. 2013. Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annu Rev Pharmacol Toxicol53:37-58. doi:10.1146/annurev-pharmtox-011112-140244
  • Morisseau C, Pakhomova S, Hwang SH, Newcomer ME, Hammock BD. 2013. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorg Med Chem Lett 23(13):3818-3821. doi:10.1016/j.bmcl.2013.04.083
  • Morisseau C, Sahdeo S, Cortopassi GA, Hammock BD. 2013. Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries. Anal Biochem434(1):105-111. doi:10.1016/j.ab.2012.11.017
  • Nording ML, Yang J, Georgi K, Karbowski CH, German JB, Weiss RH, Hogg RJ, Trygg J, Hammock BD, Zivkovic AM. 2013. Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. PLoS One8:e76575. doi:10.1371/journal.pone.0076575
  • Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW. 2013. Epoxyeicosanoids promote organ and tissue regeneration. Proceedings of the National Academy of Sciences of the United States of America (USA)110(33):13528-13533. doi:10.1073/pnas.1311565110
  • Poli G, Corda E, Martino P, Dall'Ara P, Bareggi SR, Bondiolotti G, Iulini B, Mazza M, Casalone C, Hwang SH, Hammock BD, Inceoglu B. 2013. Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie. Life Sci92(23):1145-1150. doi:10.1016/j.lfs.2013.04.014
  • Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD. 2013. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. J Agric Food Chem61(28):6964-6970. doi:10.1021/jf401302y
  • Schuchardt J, Schmidt S, Kressel G, Dong H, Willenberg I, Hammock BD, Hahn A, Schebb N. 2013. Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. Prostaglandins, Leukotrienes and Essential Fatty Acids 89(1):19-29. doi:10.1016/j.plefa.2013.04.001
  • Sirish P, Li N, Liu J, Lee KS, Hwang SH, Qiu H, Zhao C, Ma S, Lopez JE, Hammock BD, Chiamvimonvat N. 2013. Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis. Proceedings of the National Academy of Sciences of the United States of America (USA)110(14):5618-5623. doi:10.1073/pnas.1221972110 PMID:23493561 PMCID:PMC3619365
  • Smilowitz JT, Zivkovic AM, Wan YY, Watkins SM, Nording M, Hammock BD, German JB. 2013. Nutritional lipidomics: Molecular metabolism, analytics, and diagnostics. Mol Nutr Food Res 57(8):1319-1335. doi:10.1002/mnfr.201200808
  • Stewart DN, Lango J, Nambiar KP, Falso MS, Fitzgerald PG, Rocke DM, Hammock BD, Buchholz BA. 2013. Carbon turnover in the water-soluble protein of the adult human lens. Mol Vis 19:463-475.
  • Trunnelle KJ, Bennett DH, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hennessy-Burt TE, Hammock BD, Schenker MB. 2013. Pyrethroids in house dust from the homes of farm worker families in the MICASA study. Environ Int61:57-63. doi:10.1016/j.envint.2013.09.007
  • Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif A, Liu J, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. 2013. Anti-inflammatory effects of omega-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II dependent hypertension. J Cardiovasc Pharmacol 62(3):285-297. doi:10.1097/FJC.0b013e318298e460
  • Van Bogaert I, Zhang G, Yang J, Liu J, Ye Y, Soetaert W, Hammock BD. 2013. Preparation of 20- HETE using multifunctional enzyme type 2-negative Starmerella bombicola. J Lipid Res54(11):3215-3219. doi:10.1194/jlr.D042226
  • Vanrell L, Gonzalez-Techera A, Hammock BD, Gonzalez-Sapienza GG. 2013. Nanopeptamers for the development of small-analyte lateral flow tests with a positive readout. Anal Chem85(2):1177-1182. doi:10.1021/ac3031114
  • Wagner KM, Inceoglu B, Dong H, Yang J, Hwang SH, Jones PD, Morisseau C, Hammock BD. 2013. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. Eur J Pharmacol 700(1-3):93-101. doi:10.1016/j.ejphar.2012.12.015
  • Wang Y, Li P, Majkova Z, Bever C, Kim H, Zhang Q, Dechant JE, Gee SJ, Hammock BD. 2013. Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay. Anal Chem85(17):8298-8303. doi:10.1021/ac4015885
  • Wang Y, Wang H, Li P, Zhang Q, Kim H, Gee SJ, Hammock BD. 2013. Correction to: Phage- displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem61(16):3994-3994. doi:10.1021/jf401235p
  • Wang Y, Wang H, Li P, Zhang Q, Kim H, Gee SJ, Hammock BD. 2013. Phage-displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem61(10):2426–2433. doi:10.1021/jf4004048
  • Wettersten HI, Hwang SH, Li C, Shiu EY, Wecksler AT, Hammock BD, Weiss RH. 2013. A novel p21 attenuator which is structurally related to sorafenib. Cancer Biol Ther 14:278-285. doi:10.4161/cbt.23374
  • Yang J, Solaimani P, Dong H, Hammock BD, Hankinson O. 2013. Treatment of mice with 2,3,7,8- Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung. Toxicological Sciences38(6):833-836.
  • Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu J, Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. 2013. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proceedings of the National Academy of Sciences of the United States of America (USA)110(16):6530-6535. doi:10.1073/pnas.1304321110 PMID:23553837 PMCID:PMC3631682
  • Zhang W, Li H, Dong H, Liao J, Hammock BD, Yang G. 2013. Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice. Anticancer Res33(12):5261-5271. PMID:24324059 PMCID:PMC4076172

2012

  • Ahn K, Kasagami T, Tsai H, Schebb N, Ogunyoku TA, Gee SJ, Young TM, Hammock BD. 2012. An Immunoassay to Evaluate Human/Environmental Exposure to the Antimicrobial Triclocarban. Environ Sci Technol46:374-381. doi:10.1021/es202494d (Completed with ARRA Funds)
  • Cao Z, Hammock BD, McCoy MR, Rogawski MA, Lein PJ, Pessah IN. 2012. Tetramethylenedisulfotetramine alters Ca2+ dynamics in cultured hippocampal neurons: Mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. Toxicological Sciences130(2):362-372. doi:10.1093/toxsci/kfs244
  • Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos G, Schebb N, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. 2012. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proceedings of the National Academy of Sciences of the United States of America (USA)109(35):14158-14163. doi:10.1073/pnas.1211314109
  • Eiserich JP, Yang J, Morrissey BM, Hammock BD, Cross CE. 2012. Omics approaches in cystic fibrosis research: A focus on oxylipin profiling in airway secretions. Ann N Y Acad Sci1259:1-9. doi:10.1111/j.1749-6632.2012.06580.x
  • Han J, Sudheendra L, Kim H, Gee SJ, Hammock BD, Kennedy IM. 2012. Ultrasensitive on-chip immunoassays with a nanoparticle-assembled photonic crystal. ACS Nano6(10):8570-8582. doi:10.1021/nn301656c PMID:22957818 PMCID:PMC3479307
  • Inceoglu AB, Clifton HL, Yang J, Hegedus C, Hammock BD, Schaefer S. 2012. Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice. J Cardiovasc Pharmacol 60:70-75. doi:10.1097/FJC.0b013e3182580a5d
  • Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb N, Hwang SH, Morisseau C, Haj FG, Hammock BD. 2012. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of Type I Diabetes. Proceedings of the National Academy of Sciences of the United States of America (USA)109(28):11390-11395. doi:10.1073/pnas.1208708109
  • Kim H, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD, McCoy MR. 2012. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Anal Chem84(2):1165-1171. doi:10.1021/ac2030255
  • Kim H, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD. 2012. Correction to isolation of alpaca antihapten heavy chain single domain antibodies for development of sensitive immunioassay. Anal Chem84(15):6919–6919. doi:10.1021/ac301927h
  • Kim I, Nishi K, Kasagami T, Morisseau C, Liu J, Tsai H, Hammock BD. 2012. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorg Med Chem Lett 22(18):5889-5892. doi:10.1016/j.bmcl.2012.07.074
  • Lin Y, Ubels JL, Schotanus MP, Yin Z, Pintea V, Hammock BD, Watsky MA. 2012. Enhancement of vitamin D metabolites in the eye following vitamin D3 supplementation and UV-B irradiation. Curr Eye Res 37(10):871-878. doi:10.3109/02713683.2012.688235
  • McCoy MR, Yang Z, Fu X, Ahn K, Gee SJ, Bom DC, Zhong P, Chang D, Hammock BD. 2012. Monitoring of total type II pyrethroid pesticides in citrus oils and water by converting to a common product 3-phenoxybenzoic acid. J Agric Food Chem60:5065-5070. doi:10.1021/jf2051653
  • Morisseau C, Schebb N, Dong H, Ulu A, Aronov PA, Hammock BD. 2012. Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids. Biochem Biophys Res Commun419:796-800. doi:10.1016/j.bbrc.2012.02.108
  • Qiu H, Liu J, Wei D, Li N, Yamoah EN, Hammock BD, Chiamvimonvat N. 2012. Cardiac-generated prostanoids mediate cardiac myocyte apoptosis after myocardial ischaemia. Cardiovasc Res 95(3):336-345. doi:10.1093/cvr/cvs191
  • Schebb N, Ahn K, Dong H, Gee SJ, Hammock BD. 2012. Whole blood is the sample matrix of choice for monitoring systemic triclocarbon levels. Chemosphere87(7):825-827. doi:10.1016/j.chemosphere.2011.12.077 (Completed with ARRA Funds)
  • Schebb N, Buchholz BA, Hammock BD, Rice RH. 2012. Metabolism of the antibacterial triclocarban by human epidermal keratinocytes to yield protein adducts. J Biochem Mol Toxicol26(6):230-234. doi:10.1002/jbt.21411
  • Schebb N, Franze B, Maul R, Ranganathan A, Hammock BD. 2012. In Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative Metabolites. Drug Metabolism and Disposition40:25-31. (Completed with ARRA Funds)
  • Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn K, Gee SJ, Hammock BD. 2012. An enzyme-linked immunosorbent assay for detecting 3-phenoxybenzoic acid in plasma and its application to farmers and consumers. Analytical Methods4:3772-3778. doi:10.1039/c2ay25642h
  • Yang J, Eiserich JP, Cross CE, Morrissey BM, Hammock BD. 2012. Metabolomic profiling of regulatory lipid mediators in sputum from adult cystic fibrosis patients. Free Radical Biology and Medicine53(1):160-171. doi:10.1016/j.freeradbiomed.2012.05.001
  • Yao H, Liu J, Samra AI, Kamita SG, Cornel AJ, Hammock BD, Huang H. 2012. Development of pyrethroid-like fluorescent substrates for glutathione S-transferase. Anal Biochem431:77-83. doi:10.1016/j.ab.2012.09.011
  • Yueh MF, Li T, Evans RM, Hammock BD, Tukey RH. 2012. Triclocarban Mediates Induction of Xenobiotic Metabolism through Activation of the Constitutive Androstane Receptor and the Estrogen Receptor Alpha. PLoS One7(6):e37705. doi:10.1371/journal.pone.0037705 (Completed with ARRA Funds)
  • Zhang W, Yang AL, Liao J, Li H, Dong H, Chung Y, Bai H, Matkowskyj KA, Hammock BD, Yang G. 2012. Soluble epoxide hydrolase gene deficiency or inhibition attenuates chronic active inflammatory bowel disease in IL-10(-/-) mice. Dig Dis Sci 57(10):2580-2591. doi:10.1007/s10620-012-2217-1
  • Zivkovic AM, Yang J, Georgi K, Hegedus C, Nording ML, O'Sullivan A, German JB, Hogg RJ, Weiss RH, Bay C, Hammock BD. 2012. Serum oxylipin profiles in lgA nephropathy patients reflect kidney functional alterations. Metabolomics8(6):1102-1113. doi:10.1007/s11306-012-0417-5
  • Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. 2012. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. Journal of Pharmacology and Experimental Therapeutics341(2):435-446. doi:10.1124/jpet.111.190579

2011

  • Abdu E, Bruun DA, Yang DR, Yang J, Inceoglu B, Hammock BD, Alkayed NJ, Lein PJ. 2011. Epoxyeicosatrienoic acids enhance axonal growth in primary sensory and cortical neuronal cell cultures. J Neurochem117:632-642. doi:10.1111/j.1471-4159.2010.07139.x
  • Ahn K, Gee SJ, Aronov PA, Vega H, Krieger RI, Hammock BD, Kim H. 2011. Immunochemical analysis of 3-phenoxybenzoic acid, a biomarker of forestry worker exposure to pyrethroid insecticides. Anal Bioanal Chem401(4):1285-1293. doi:10.1007/s00216-011-5184-z
  • Ahn K, Kim H, McCoy MR, Gee SJ, Hammock BD. 2011. Immunoassays and biosensors for monitoring environmental and human exposure to pyrethroid insecticides. J Agric Food Chem59(7):2792-2802. doi:10.1021/jf1033569
  • Barhoumi R, Mouneimne Y, Hammock BD, Safe SH, Parrish AR, Burghardt RC, Ramos E. 2011. Multiphoton spectral analysis of benzo a pyrene uptake and metabolism in a rat liver cell line. Toxicol Appl Pharmacol253:45-56. doi:10.1016/j.taap.2011.03.009
  • Charles RL, Burgoyne JR, Mayr M, Weldon SM, Hubner N, Dong H, Morisseau C, Hammock BD, Landar A, Eaton P. 2011. Redox regulation of soluble epoxide hydrolase by 15-Deoxy-AProstaglandin J2 controls coronary hypoxic vasodilation. Circ. Res. Circ Res108:324-334. doi:10.1161/CIRCRESAHA.110.235879
  • Davis BB, Liu J, Tancredi DJ, Wang L, Simon SI, Hammock BD, Pinkerton KE. 2011. The anti-inflammatory effects of soluble epoxide hydrolase inhibitors are independent of leukocyte recruitment. Biochem Biophys Res Commun410:494-500.
  • Gee SJ, Gonazlez-Sapienza GG, Hammock BD, Kim H, McCoy MR. 2011. Noncompetitive phage anti-immunocomplex real-time polymerase chain reaction for sensitive detection of small molecules. Anal Chem83(1):246-253. doi:10.1021/ac102353z
  • Honetschlagerova Z, Huskova Z, Vanourkova Z, Sporkova A, Kramer HJ, Hwang SH, Tsai H, Hammock BD, Imig JD, Cervenka L, Kopkan L. 2011. Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension. Journal of Physiology-London 589:207-219. doi:10.1113/jphysiol.2010.199505 PMID:21078594 PMCID:PMC3039270
  • Hwang SH, Wagner KM, Morisseau C, Liu J, Dong H, Wecksler AT, Hammock BD. 2011. Synthesis and Structure-Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase. J Med Chem54:3037-3050. doi:10.1021/jm2001376
  • Inceoglu B, Wagner KM, Schebb N, Morisseau C, Jinks SL, Ulu A, Hegedus C, Rose TE, Hammock BD, Brosnan R. 2011. Analgesia mediated by soluble epoxide hydrolase inhibitors is dependent on cAMP. Proceedings of the National Academy of Sciences of the United States of America (USA)108:5093-5097. doi:10.1073/pnas.1101073108
  • Inoue H, Hwang SH, Wecksler AT, Hammock BD, Weiss RH. 2011. Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy. Cancer Biol Ther 12:827-836. doi:10.4161/cbt.12.9.17680
  • Kamita SG, Samra AI, Liu J, Cornel AJ, Hammock BD. 2011. Juvenile Hormone (JH) Esterase of the Mosquito Culex quinquefasciatus Is Not a Target of the JH Analog Insecticide Methoprene. PLoS One6:doi:10.1371/journal.pone.0028392
  • Kim Y, Lee E, Kim K, Lee YT, Hammock BD, Lee H. 2011. Competitive immunochromatographic assay for the detection of the organophosphorus pesticide chlorpyrifos. Anal Chim Acta693(1-2):106-113. doi:10.1016/j.aca.2011.03.011
  • Koeners MP, Wesseling S, Ulu A, Sepulveda R, Morisseau C, Braam B, Hammock BD, Joles JA. 2011. Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats. American Journal of Physiology - Endocrinology and Metabolism300:E691-698. doi:10.1152/ajpendo.00710.2010
  • Li YY, Liu J, Harris TR, Sirish P, Hammock BD, Chiamvimonvat N. 2011. Use of metabolomics profiling in the study of arachidonic acid metabolism in cardiovascular disease. American Journal of Cardiology17:42-46. doi:10.1111/j.1751-7133.2010.00209.x
  • Liu J, Qiu H, Moisseau C, Hwang SH, Tsai H, Ulu A, Chiamvimonvat N, Hammock BD. 2011. Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model. Toxicol Appl Pharmacol255:200-206. doi:10.1016/j.taap.2011.06.017
  • Luria A, Bettaieb A, Xi Y, Shieh G, Liu H, Inoue H, Tsai H, Imig JD, Haj FG, Hammock BD. 2011. Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance. Proceedings of the National Academy of Sciences of the United States of America (USA)108(22):9038-9043. doi:10.1073/pnas.1103482108
  • Morisseau C, Bernay M, Escaich A, Sanborn JR, Lango J, Hammock BD. 2011. Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies. Anal Biochem414:154-162. doi:10.1016/j.ab.2011.02.038
  • Qiu H, Li N, Liu J, Harris TR, Hammock BD, Chiamvimonvat N. 2011. Soluble epoxide hydrolase inhibitors and heart failure. Cardiovasc Ther 29:99-111. doi:10.1111/j.1755-5922.2010.00150.x PMID:20433684 PMCID:PMC3325372
  • Schebb N, Huby M, Morisseau C, Hwang SH, Hammock BD. 2011. Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors. Anal Bioanal Chem400(5):1359-1366.
  • Schebb N, Inceoglu B, Ahn K, Morisseau C, Gee SJ, Hammock BD. 2011. Investigation of Human Exposure to Triclocarban after Showering and Preliminary Evaluation of Its Biological Effects. Environ Sci Technol45:3109-3115. doi:10.1021/es103650m (Completed with ARRA Funds)
  • Schebb N, Inceoglu B, Ahn K, Morrisseau C, Gee SJ, Hammock BD. 2011. Development of an online SPE-LC-MS-based assay using endogenous substrate for the investigation of soluble epoxide hydrolase (sEH) inhibitors. Anal. Bioanal. Chem. Anal Bioanal Chem400:1359-1366. doi:10.1007/s00216-011-4861-2
  • Schebb N, Inceoglu B, Rose TE, Wagner KM, Hammock BD. 2011. Development of an ultra fast online-solid phase extraction (SPE) liquid chromatography electrospray tandem mass spectrometry (LC-ESI-MS/MS) based approach for the determination of drugs in pharmacokinetic studies. Analytical Methods3:420-428. doi:10.1039/c0ay00714e
  • Schebb N, Kurobe T, Franze B, Ranganathan A, Hammock BD, Teh SJ, Flores I. 2011. Bioconcentration, metabolism and excretion of triclocarban in larval Qurt medaka (Oryzias latipes). Aquatic Toxicology105:448-454. doi:10.1016/j.aquatox.2011.07.020
  • Sporkova A, Kopkan L, Varcabova S, Huskova Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Cervenka L. 2011. Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats. American Journal of Physiology - Regulatory, Integrative and Comparative Physiology300:R1468-R1475. doi:10.1152/ajpregu.00215.2010
  • Tabares-da Rosa S, Rossotti MA, Carleiza C, Carrion F, Pritsch O, Ahn K, Last JA, Hammock BD, Gonzalez-Sapienza GG. 2011. Competitive Selection from Single Domain Antibody Libraries Allows Isolation of High-Affinity Antihapten Antibodies That Are Not Favored in the llama Immune Response. Anal Chem83:7213-7220. doi:10.1021/ac201824z
  • Wagner KM, Inceoglu B, Gill S, Hammock BD. 2011. Epoxygenated Fatty Acids and Soluble Epoxide Hydrolase Inhibition: Novel Mediators of Pain Reduction. J Agric Food Chem59:2816-2824. doi:10.1021/jf102559q
  • Wagner KM, Inceoglu B, Hammock BD. 2011. Soluble epoxide hydrolase inhibition, epoxygenated fatty acids and nociception. Prostaglandins Other Lipid Mediat 96:76-83. doi:10.1016/j.prostaglandins.2011.08.001
  • Yang J, Dong H, Hammock BD. 2011. Profiling the regulatory lipids: another systemic way to unveil the biological mystery. Curr Opin Lipidol 22:197-203. doi:10.1097/MOL.0b013e3283468c10
  • Ye X, Zhou X, Furr J, Ahn K, Hammock BD, Gray EL, Calafat AM. 2011. Biomarkers of exposure to triclocarban in urine and serum. Toxicology286(1-30):69-74. doi:10.1016/j.tox.2011.05.008 (Completed with ARRA Funds)
  • Yin Z, Pintea V, Lin Y, Hammock BD, Watsky MA. 2011. Vitamin D enhances corneal epithelial barrier function. Invest Ophthalmol Vis Sci52:7359-7364. doi:10.1167/iovs.11-7605

2010

  • Alihosseini F, Lango J, Ju K, Hammock BD, Sun G. 2010. Mutation of bacterium Vibrio gazogenes for selective preparation of colorants. Biotechnol Prog26(2):352-360. doi:10.1002/btpr.346
  • Baumann A, Lohmann W, Rose TE, Ahn K, Hammock BD, Karst U, Schebb N. 2010. Electrochemistry-mass spectrometry unveils the formation of reactive triclocarban metabolites. Drug Metabolism and Disposition38(12):2130-2138. doi:10.1124/dmd.110.034546 (Completed with ARRA Funds)
  • Carlomagno M, Matho C, Cantou G, Sanborn JR, Last JA, Hammock BD, Roel A, Gonzalez D, Gonzalez-Sapienza GG. 2010. A Clomazone Immunoassay To Study the Environmental Fate of the Herbicide in Rice (Oryza sativa) Agriculture. J Agric Food Chem58(7):4367-4371. doi:10.1021/jf9043259
  • Chabova VC, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kujal P, Vernerova Z, Vanourkova Z, Kopkan L, Kramer HJ, Imig JD, Hammock BD, Vaneckova I, Cervenka L, Falck JR. 2010. Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats. Clin Sci 118:617-632. doi:10.1042/cs20090459
  • Garcia-Nieto E, Nichkova MJ, Yanez L, Costilla-Salazar R, Torres-Dosal A, Gee SJ, Hammock BD, Juarez-Santacruz L, Diaz-Barriga F. 2010. Assessment of Dioxin-Like Soil Contamination in Mexico by Enzyme-Linked Immunosorbent Assay. Arch Environ Contam Toxicol58(4):918-926. doi:10.1007/s00244-009-9422-8
  • Hall LM, Kimlin M, Aronov PA, Hammock BD, Slusser J, Woodhouse L, Stephensen CB. 2010. Vitamin D Intake Needed to Maintain Target Serum 25-Hydroxyvitamin D Concentrations in Participants with Low Sun Exposure and Dark Skin Pigmentation Is Substantially Higher Than Current Recommendations. Journal of Nutrition140(3):542-550. doi:10.3945/jn.109.115253
  • Kim H, Rossotti MA, Ahn K, Gonzalez-Sapienza GG, Gee SJ, Musker R, Hammock BD. 2010. Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47. Anal Biochem401(1):38-46. doi:10.1016/j.ab.2010.01.040
  • Kubala L, Schmelzer KR, Klinke A, Kolarova H, Baldus S, Hammock BD, Eiserich JP. 2010. Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. Free Radical Biology & Medicine,. Free Radical Biology and Medicine48(10):1311-1320. doi:10.1016/j.freeradbiomed.2010.02.010
  • Liu J, Li N, Yang J, Li N, Qiu H, Ai D, Chiamvimonvat N, Zhu Y, Hammock BD. 2010. Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events. Proceedings of the National Academy of Sciences of the United States of America (USA)107(39):17017-17022. doi:10.1073/pnas.1011278107
  • Morisseau C, Inceoglu B, Schmelzer KR, Tsai H, Jinks SL, Hegedus CM, Hammock BD. 2010. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. J Lipid Res51:3481-3490. doi:10.1194/jlr.M006007
  • Nording ML, Yang J, Hegedus CM, Bhushan A, Kenyon NJ, Davis CE, Hammock BD. 2010. Endogenous levels of five fatty acid metabolites in exhaled breath condensate to monitor asthma by high-performance liquid chromatography: Electrospray tandem mass spectrometry. IEEE Sensors Journal10(1):123-130. doi:10.1109/JSEN.2009.2035736
  • Rayo J, Munoz L, Rosell G, Hammock BD, Guerrero A, Luque FJ, Pouplana R. 2010. Reactivity versus steric effects in fluorinated ketones as esterase inhibitors: a quantum mechanical and molecular dynamics study. J Mol Model16(11):1753-1764. doi:10.1007/s00894-010-0807-4
  • Rose TE, Morisseau C, Liu J, Inceoglu B, Jones PD, Sanborn JR, Hammock BD. 2010. 1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure-Activity Relationships, Pharmacokinetics, and Reduction of Inflammatory Pain. J Med Chem53(19):7067-7075. doi:10.1021/jm100691c
  • Rossotti MA, Carlomagno M, Gonzalez-Techera A, Hammock BD, Last JA, Gonzalez-Sapienza GG. 2010. Phage anti-immunocomplex assay for clomazone: Two-site recognition increasing assay specificity and facilitating adaptation into an on-site format. Anal Chem82(21):8838-8843. doi:10.1021/ac101476f
  • Tsai H, Hwang SH, Morisseau C, Yang J, Jones PD, Kasagami T, Kim I, Hammock BD. 2010. Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs. European Journal of Pharmaceutical Sciences 40(3):222-238. doi:10.1016/j.ejps.2010.03.018
  • Wang Y, Ulu A, Zhang L, Hammock BD. 2010. Soluble Epoxide Hydrolase in Atherosclerosis. Curr Atheroscler Rep 12:174-183. doi:10.1007/s11883-010-0108-5

2009

  • Ahn K, Gee SJ, Tsai H, Bennett DH, Nishioka M, Blum A, Fishman E, Hammock BD. 2009. Immunoassay for Monitoring Environmental and Human Exposure to the Polybrominated Diphenyl Ether BDE-47. Environ Sci Technol43(20):7784-7790. doi:10.1021/es9009037
  • Ai D, Pang W, Li N, Xu M, Jones PD, Yang J, Zhang Y, Chiamvimonvat N, Shyy JY, Hammock BD, Zhu Y. 2009. Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy. Proceedings of the National Academy of Sciences of the United States of America (USA)106(2):564-569. doi:10.1073/pnas.0811022106
  • Barbosa-Sicard E, Fromel T, Keseru B, Brandes RP, Morisseau C, Hammock BD, Braun T, Kruger M, Fleming I. 2009. Inhibition of the Soluble Epoxide Hydrolase by Tyrosine Nitration. Journal of Biological Chemistry284:28156-28163. doi:10.1074/jbc.M109.054759
  • Chawengsub Y, Gauthier KM, Nithipatikom K, Hammock BD, Falck JR, Narsimhaswamy D, Campbell WB. 2009. Identification of 13-Hydroxy-14,15-epoxyeicosatrienoic Acid as an Acid-stable Endothelium-derived Hyperpolarizing Factor in Rabbit Arteries. Journal of Biological Chemistry284:31280-31290. doi:10.1074/jbc.M109.025627
  • Falck JR, Kodela R, Manne R, Atcha KR, Puli N, Dubasi N, Manthati VL, Capdevila JH, Yi X, Goldman DH, Morisseau C, Hammock BD, Campbell WB. 2009. 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: Influence upon vascular relaxation and soluble epoxide hydrolase inhibition. J Med Chem52(16):5069. doi:10.1021/jm900634w
  • Huang H, Tanaka H, Hammock BD, Morisseau C. 2009. Novel and highly sensitive fluorescent assay for leucine aminopeptidases. Anal Biochem391(1):11-16. doi:10.1016/j.ab.2009.05.004
  • Inceoglu AB, Waite T, Christiansen JA, McAbee RD, Kamita SG, Hammock BD, Cornel AJ. 2009. A rapid luminescent assay for measuring cytochrome P450 activity in individual larval Culex pipiens complex mosquitoes (Diptera: Culicidae). J Med Entomol 46(1):83-92. doi:10.1603/033.046.0111
  • Kasagami T, Kim I, Tsai H, Nishi K, Hammock BD, Morisseau C. 2009. Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities. Bioorg Med Chem Lett 19(6):1784-1789. doi:10.1016/j.bmcl.2009.01.069
  • Kim HJ, Ahn K, Gonzalez-Techera A, Gonzalez-Sapienza GG, Gee SJ, Hammock BD. 2009. Magnetic bead-based phage anti-immunocomplex assay (PHAIA) for the detection of the urinary biomarker 3-phenoxybenzoic acid to assess human exposure to pyrethroid insecticides. Anal Biochem386(1):45-52. doi:10.1016/j.ab.2008.12.003
  • Li N, Liu J, Timofeyev V, Qiu H, Hwang SH, Tuteja D, Lu L, Yang J, Mochida H, Low R, Hammock BD, Chiamvimonvat N. 2009. Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches. Journal of Molecular & Cellular Cardiology 47(6):835-845. doi:10.1016/j.yjmcc.2009.08.017
  • Liu J, Park S, Morisseau C, Hwang SH, Hammock BD, Weiss RH. 2009. Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo. Mol Cancer Ther8(8):2193-2203. doi:10.1158/1535-7163.MCT-09-0119
  • Liu J, Tsai H, Hwang SH, Jones PD, Morisseau C, Hammock BD. 2009. Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation. Br J Pharmacol156(2):284-296. doi:10.1111/j.1476-5381.2008.00009.x
  • Lu C, Schoenfeld R, Shan Y, Tsai H, Hammock BD, Cortopassi GA. 2009. Frataxin deficiency induces Schwann cell inflammation and death. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease1792(11):1052-1061. doi:10.1016/j.bbadis.2009.07.011
  • Luria A, Morisseau C, Tsai H, Yang J, Inceoglu B, De Taeye B, Wiest MM, German JB, Hammock BD, Watkins SM. 2009. Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase. American Journal of Physiology - Endocrinology and Metabolism297(2):E375-E383. doi:10.1152/ajpendo.00131.2009
  • Ma Z, Dosev D, Nichkova MJ, Dumas RK, Gee SJ, Hammock BD, Kennedy IM. 2009. Synthesis and characterization of multifunctional silica core-shell nanocomposites with magnetic and fluorescent functionalities. Journal of Magnetism and Magnetic Materials321(10):1368-1371. doi:10.1016/j.jmmm.2009.02.040
  • Ma Z, Dosev D, Nichkova MJ, Gee SJ, Hammock BD, Kennedy IM. 2009. Synthesis and bio-functionalization of multifunctional magnetic Fe3O4@Y2O3:Eu nanocomposites. Journal of Materials Chemistry19:4695-4700. doi:10.1039/B901427F
  • Matveeva EG, Morisseau C, Goodrow MH, Mullin C, Hammock BD. 2009. Tryptophan fluorescence quenching by enzyme inhibitors as a tool for enzyme active site structure investigation: epoxide hydrolase. Curr Pharm Biotechnol10(6):589-599. doi:10.2174/138920109789069260
  • Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. 2009. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect 117(12):1867-1872.
  • Nichkova MJ, Fu X, Yang Z, Zhong P, Sanborn JR, Chang D, Gee SJ, Hammock BD. 2009. Immunochemical Screening of Pesticides (Simazine and Cypermethrin) in Orange Oil. J Agric Food Chem57(13):56735679. doi:10.1021/jf900652a
  • Parrish AR, Chen G, Burghardt RC, Watanabe T, Hammock BD, Morisseau C. 2009. Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase. Cell Biol Toxicol 25(3):217-225. doi:10.1007/s10565-008-9071-0
  • Shen S, Zhang F, Zeng S, Tian Y, Chai X, Gee SJ, Hammock BD, Zheng J. 2009. Development of Enantioselective Polyclonal Antibodies to Detect Styrene Oxide Protein Adducts. Anal Chem81(7):2668-2677. doi:10.1021/ac8023262
  • Yang J, Schmelzer KR, Georgi K, Hammock BD. 2009. Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry. Anal Chem81(19):8085-8093. doi:10.1021/ac901282n

2008

  • Aronov PA, Hall LM, Dettmer K, Stephensen CB, Hammock BD. 2008. Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem391(5):1917-30. doi:10.1007/s00216-008-2095-8
  • Aronova S, Wedaman K, Aronov PA, Fontes K, Ramos K, Hammock BD, Powers T. 2008. Regulation of ceramide biosynthesis by TOR complex 2. Cell Metab7(2):148-158. doi:10.1016/j.cmet.2007.11.015
  • Barbosa-Sicard E, Popp R, Fisslthaler B, Hammock BD, Falck JR, Busse R, Fleming I, Keseru B, Dietrich A, Gudermann T, Weissmann N. 2008. Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response. FASEB Journal22(12):4306-15. doi:10.1096/fj.08-112821
  • Bradbury JA, Graves J, Degraff LM, Zhao X, Imig JD, Pedersen TL, Newman JW, Hammock BD, Conley AJ, Korach KS, Zeldin DC, Athirakul K, Ma J, Zhao Y, Couse JF, Quigley R, Harder DR, Coffman TM. 2008. Increased blood pressure in mice lacking cytochrome P450 2J5. FASEB Journal22(12):4096-108. doi:10.1096/fj.08-114413
  • Chawengsub Y, Aggarwal N, Nithipatikom K, Gauthier KM, Anjaiah S, Hammock BD, Falck JR, Campbell WB. 2008. Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta. American Journal of Physiology - Heart and Circulatory Physiology294(3):1348-56.
  • Chen J, Ahn K, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, Lasley BL. 2008. Triclocarban enhances testosterone action: a new type of endocrine disruptor?. Endocrinology149(3):1173-1179. doi:10.1210/en.2007-1057
  • Chen J, Ahn K, Zhao B, Denison MS, Lasley BL, Pessah IN, Kültz D, Chang DP, Gee SJ, Hammock BD, Cherednichenko G. 2008. In Vitro Biologic Activities of the Antimicrobials Triclocarban, Its Analogs, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens. Environ Health Perspect 116:1203-1210. doi:10.1289/ehp.11200
  • Corenblum MJ, Wise VE, Georgi K, Hammock BD, Doris PA, Fornage M. 2008. Altered soluble epoxide hydrolase gene expression and function and vascular disease risk in the stroke-prone spontaneously hypertensive rat. Hypertension51(2):567-73.
  • Dreisbach AW, Rice JC, Japa S, Newman JW, Sigel A, Gill R, Hess AE, Cemo AC, Fonseca JP, Hammock BD, Lertora JJ, Hamm LL. 2008. Salt loading increases urinary excretion of linoleic acid diols and triols in healthy human subjects. Hypertension51:755-761.
  • Enayetallah AE, Luria A, Luo B, Tsai H, Sura P, Hammock BD, Grant DF. 2008. Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase. Journal of Biological Chemistry283:36592-8. doi:10.1074/jbc.M806315200
  • Fife KL, Liu Y, Schmelzer KR, Tsai H, Kim I, Morisseau C, Hammock BD, Kroetz DL. 2008. Inhibition of Soluble Epoxide Hydrolase Does Not Protect against Endotoxin-Mediated Hepatic Inflammation. Journal of Pharmacology and Experimental Therapeutics327:707-715. doi:10.1124/jpet.108.142398
  • Gonzalez-Techera A, Umpierrez-Failache M, Cardozo S, Obal G, Last JA, Gee SJ, Hammock BD, Gonzalez-Sapienza GG, Pritsch O. 2008. High-throughput method for ranking the affinity of peptide ligands selected from phage display libraries. Bioconjug Chem19(5):993-1000. doi:10.1021/bc700279y
  • Gross GJ, Gauthier KM, Moore J, Falck JR, Hammock BD, Campbell WB, Nithipatikom K. 2008. Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. American Journal of Physiology - Heart and Circulatory Physiology294(6):H2838-44. doi:10.1152/ajpheart.00186.2008
  • Harris TR, Aronov PA, Hammock BD. 2008. Soluble epoxide hydrolase homologs in Strongylocentrotus purpuratus suggest a gene duplication event and subsequent divergence. DNA Cell Biol27(9):467-77. doi:10.1089/dna.2008.0751
  • Hwang H, Park E, Young TM, Hammock BD. 2008. Occurrence of endocrine-disrupting chemicals in indoor dust. Science of the Total Environment404(1):26-35. doi:10.1016/j.scitotenv.2008.05.031
  • Inceoglu B, Jinks SL, Ulu A, Hegedus CM, Georgi K, Schmelzer KR, Wagner KM, Jones PD, Morisseau C, Hammock BD. 2008. Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proceedings of the National Academy of Sciences of the United States of America (USA)105(48):18901-18906. doi:10.1073/pnas.0809765105
  • Jiang H, Zhu AG, Mamczur M, Morisseau C, Hammock BD, Falck JR, McGiff JC. 2008. Hydrolysis of cis- and trans-epoxyeicosatrienoic acids by rat red blood cells. Journal of Pharmacology and Experimental Therapeutics326(1):330-7. doi:10.1124/jpet.107.134858
  • Kim HJ, Gonzalez-Techera A, Gonzalez-Sapienza GG, Ahn K, Gee SJ, Hammock BD. 2008. Phage-borne peptidomimetics accelerate the development of polyclonal antibody-based heterologous immunoassays for the detection of pesticide metabolites. Environ Sci Technol42(6):2047-53. doi:10.1021/es702219a
  • Morisseau C, Hammock BD. 2008. Gerry Brooks and epoxide hydrolases: four decades to a pharmaceutical. Pest Manag Sci 64(6):594-609. doi:10.1002/ps.1583
  • Morisseau C, Newman JW, Wheelock CE, Hill T, Morin D, Buckpitt AR, Hammock BD. 2008. Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. Chem Res Toxicol21(4):951-7. doi:10.1021/tx700446u
  • Park E, Duarte Tagles H, Gee SJ, Hammock BD, Lee K, Schenker MB. 2008. Recruiting strategy and 24-hour biomonitoring of paraquat in agricultural workers. J Agromedicine 13(4):207-17.
  • Pedersen TL, Grekin RJ, Hammock BD, Ball DL, Vollmer A. 2008. Heparin, lipoproteins, and oxygenated fatty acids in blood: a cautionary note. Prostaglandins, Leukotrienes and Essential Fatty Acids 77(5-6):363-366. doi:10.1016/j.plefa.2007.10.012
  • Tanaka H, Kamita SG, Wolf NM, Harris TR, Wu Z, Morisseau C, Hammock BD. 2008. Transcriptional regulation of the human soluble expoxide hydrolase gene EPHX2. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms1779(1):17-27. doi:10.1016/j.bbagrm.2007.11.005
  • Van Emon JM, Chuang J, Lordo RA, Schrock ME, Nichkova MJ, Gee SJ, Hammock BD. 2008. An enzyme-linked immunosorbent assay for the determination of dioxins in contaminated sediment and soil samples. Chemosphere72(1):95-103. doi:10.1016/j.chemosphere.2008.01.012
  • Wheelock CE, Forshed J, Goto S, Hammock BD, Newman JW. 2008. Effects of Pyridine Exposure upon Structural Lipid Metabolism in Swiss Webster Mice. Chem Res Toxicol21(3):583-90. doi:10.1021/tx7002454
  • Wheelock CE, Nishi K, Jones PD, Colvin ME, Olmstead MM, Hammock BD. 2008. Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH). Bioorg Med Chem16(4):2114-30. doi:10.1016/j.bmc.2007.10.081
  • Wheelock CE, Phillips BM, Miller JL, Miller MG, Hammock BD. 2008. Applications of carboxylesterase activity in environmental monitoring and Toxicity Identification Evaluations (TIEs). Rev Environ Contam Toxicol195:doi:10.1007/978-0-387-77030-7

2007

  • Ahn K, Lohstroh PN, Gee SJ, Gee NA, Lasley BL, Hammock BD. 2007. High-throughput automated luminescent magnetic particle-based immunoassay to monitor human exposure to pyrethroid insecticides. Anal Chem79(b):8883-90.
  • Ai D, Fu Y, Guo D, Tanaka H, Wang N, Tang C, Hammock BD, Shyy JY, Zhu Y. 2007. Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America (USA)104(21):9018-23.
  • Akatsuka T, Ishikawa T, Kobayashi N, Saito T, Shindo M, Yamauchi M, Kurokohchi K, Miyazawa H, Duan H, Matsunaga T, Komoda T, Morisseau C, Hammock BD. 2007. Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A. J Autoimmun 28(1):7-18. doi:10.1016/j.jaut.2006.12.005
  • Chen J, Ahn K, Gee SJ, Gee NA, Hammock BD, Lasley BL. 2007. Antiandrogenic properties of parabens and other phenolic containing small molecules in personal care products. Toxicol Appl Pharmacol221(a):278-284.
  • Chiamvimonvat N, Ho C, Tsai H, Hammock BD. 2007. The soluble epoxide hydrolase as a pharmaceutical target for hypertension. J Cardiovasc Pharmacol 50:225-237.
  • Chiappe C, Leandri E, Hammock BD, Morisseau C. 2007. Effect of ionic liquids on epoxide hydrolase-catalyzed synthesis of chiral 1,2-diols. Green Chemistry9:162-168. doi:10.1039/B612106C
  • Dettmer K, Aronov PA, Hammock BD. 2007. Mass spectrometry-based metabolomics. Mass Spectrom Rev26(1):51-78.
  • Dettmer K, Hanna D, Whetstone P, Hansen R, Hammock BD. 2007. Autism and urinary exogenous neuropeptides: development of an on-line SPE-HPLC-tandem mass spectrometry method to test the opioid excess theory. Anal Bioanal Chem388:1643-1651.
  • Devonshire AL, Heidari R, Huang H, Hammock BD, Russell RJ, Oakeshott JG. 2007. Hydrolysis of individual isomers of fluorogenic pyrethroid analogs by mutant carboxylesterases from Lucilia cuprina. Insect Biochem Mol Biol 37:891-902.
  • Dosev D, Nichkova MJ, Dumas RK, Gee SJ, Hammock BD, Liu K, Kennedy IM. 2007. Magnetic/luminescent core/shell particles synthesized by spray pyrolysis and their application in immunoassays with internal standard. Nanotechnology18(5):055102(6pp).
  • Endsley MP, Aggarwal N, Isbell MA, Wheelock CE, Hammock BD, Flack JR, Nithipatikom K, Campbell WB. 2007. Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: location, hydrolysis and 12-lipoxygenase metabolism. Int J Cancer121:984-991.
  • Fleming I, Rueben A, Popp R, Fisslthaler B, Sander A, Haendeler J, Falck JR, Morisseau C, Hammock BD, Busse R. 2007. Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells. Arteriosclerosis, Thrombosis and Vascular Biology27(12):2612-8.
  • Gonzalez-Techera A, Kim HJ, Gee SJ, Last JA, Hammock BD. 2007. Polyclonal Antibody-Based Noncompetitive Immunoassay for Small Analytes Developed with Short Peptide Loops Isolated from Phage Libraries. Anal Chem79:9191-9196. doi:10.1021/ac7016713
  • Gonzalez-Techera A, Vanrell L, Last JA, Hammock BD, Gonzalez-Sapienza GG. 2007. Phage anti-immune complex assay: general strategy for noncompetitive immunodetection of small molecules. Anal Chem79(20):7799-806. doi:10.1021/ac071323h
  • Hillard CJ, Ho WS, Thompson J, Gauthier KM, Wheelock CE, Huang H, Hammock BD. 2007. Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. Br J Pharmacol152(5):691-8.
  • Huang H, Nishi K, Tsai H, Hammock BD. 2007. Development of highly sensitive fluorescent assays for fatty acid amide hydrolase. Anal Biochem363(1):12-21.
  • Hwang SH, Tsai H, Liu J, Morisseau C, Hammock BD. 2007. Orally bioavailable potent soluble epoxide hydrolase inhibitors. J Med Chem50:3825-3840.
  • Inceoglu B, Schmelzer KR, Morisseau C, Jinks SL, Hammock BD. 2007. Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs). Prostaglandins Other Lipid Mediat 82(1-4):42-49.
  • Kim H, Gee SJ, Li QX, Hammock BD. 2007. Noncompetitive Fluorescent Immunoassay for the Detection of the Human Urinary Biomarker 3-Phenoxybenzoic Acid with Bench Top Immunosensor KinExATM 3000. Chapter 11in: Rational Environmental Management of Agrochemicals: Risk Assessment, Monitoring, and Remedial Action. pp.171185.
  • Kim HJ, Ahn K, Ma S, Gee SJ, Hammock BD. 2007. Development of sensitive immunoassays for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroid exposure. J Agric Food Chem55(10):3750-7.
  • Kim I, Nishi K, Tsai H, Bradford T, Koda Y, Watanabe T, Morisseau C, Blanchfield J, Toth I, Hammock BD. 2007. Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorg Med Chem15(1):312-23.
  • Kim I, Tsai H, Nishi K, Kasagami T, Morisseau C, Hammock BD. 2007. 1,3-Disubstituted ureas functionalized with ether groups and potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic properties. J Med Chem50:5217-5226.
  • Loch D, Hoey A, Morisseau C, Hammock BD, Brown L. 2007. Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase. Cell Biochem Biophys 47:87-97.
  • Luria A, Weldon SM, Kabcenell AK, Ingraham RH, Matera D, Jiang H, Gill R, Morisseau C, Newman JW, Hammock BD. 2007. Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice. Journal of Biological Chemistry282(5):2891-8.
  • Newman JW, Kaysen GA, Hammock BD, Shearer GC. 2007. Proteinuria increases oxylipid concentrations in VLDL and HDL, but not LDL particles in the rat. J Lipid Res48:1792-1800.
  • Nichkova MJ, Dosev D, Davies AE, Gee SJ, Kennedy IM, Hammock BD. 2007. Multiplexed immunoassays for biomonitoring of exposure to agrochemicals using quantum dots as fluorescent reporters. Proceedings of SPIE 6448:644817-1. doi:10.1117/12.699231
  • Nichkova MJ, Dosev D, Davies AE, Gee SJ, Kennedy IM, Hammock BD. 2007. Quantum dots as reporters in multiplexed immunoassays for biomarkers of exposure to agrochemicals. Analytical Letters 40(7):1423-1433. doi:10.1080/00032710701327088
  • Nichkova MJ, Dosev D, Gee SJ, Hammock BD, Kennedy IM. 2007. Multiplexed immunoassays for proteins using magnetic luminescent nanoparticles for internal calibration. Anal Biochem369(a):34-40.
  • Park E, Mak SK, Hammock BD, Kültz D. 2007. Evaluation of cytotoxicity attributed to thimerosal on murine and human kidney cells. Journal of Toxicology and Environmental Health Part A70(24):2092-5.
  • Park E, Mak SK, Kültz D, Hammock BD. 2007. Determination of cytotoxicity of nephrotoxins on murine and human kidney cell lines. Journal of Environmental Science and Health, Part B43:71-74.
  • Thompson DA, Hammock BD. 2007. Dihydroxyoctadecamonoenoate esters inhibit the neutrophil respiratory burst. J Biosci 32(2):279-91.
  • Wadkins RM, Hyatt JL, Edwards CC, Tsurkan L, Redinbo MR, Wheelock CE, Jones PD, Hammock BD, Potter PM. 2007. Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds. Mol Pharmacol71(3):713-723.
  • Wheelock CE, Goto S, Hammock BD, Newman JW. 2007. Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics3:137-145.
  • Yuan W, Chung JS, Gee SJ, Hammock BD, Zheng J. 2007. Development of polyclonal antibodies for detection of styrene oxide modified proteins. Chem Res Toxicol20:316-321.
  • Zhang W, Koerner IP, Noppens R, Grafe M, Tsai H, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ. 2007. Soluble epoxide hydrolase: a novel therapeutic target in stroke. Journal of Cerebral Blood Flow & Metabolism 27(12):1931-40.

2006

  • Ahn K, Ma S, Tsai H, Gee SJ, Hammock BD. 2006. An immunoassay for a urinary metabolite as a biomarker of human exposure to the pyrethroid insecticide permethrin. Anal Bioanal Chem384(3):713-722.
  • Carkeet C, Dueker SR, Lango J, Buchholz BA, Miller JW, Green R, Hammock BD, Roth JR, Anderson PJ. 2006. Human vitamin B12 absorption measurement by accelerator mass spectrometry using specifically labeled 14C-cobalamin. Proceedings of the National Academy of Sciences of the United States of America (USA)103(15):5694-5699.
  • Cummins CM, Koivunen ME, Stephanian A, Gee SJ, Hammock BD, Kennedy IM. 2006. Application of europium(III) chelate-dyed nanoparticle labels in a competitive atrazine fluoroimmunoassay on an ITO waveguide. Biosens Bioelectron21(7):1077-1085.
  • Davis BB, Morisseau C, Newman JW, Pedersen TL, Hammock BD, Weiss RH. 2006. Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition. Journal of Pharmacology and Experimental Therapeutics316(2):815-821.
  • Gomez GA, Morisseau C, Hammock BD, Christianson DW. 2006. Human soluble epoxide hydrolase: Structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids. Protein Science15(1):58-64.
  • Harris TR, Morisseau C, Walzem RL, Ma S, Hammock BD. 2006. The cloning and characterization of a soluble epoxide hydrolase in chicken. Poult Sci82(2):278-287.
  • Huang H, Nishi K, Gee SJ, Hammock BD. 2006. Evaluation of chiral -cyanoesters as general fluorescent substrates for screening enantioselective esterases. J Agric Food Chem54(3):694-699.
  • Hwang SH, Morisseau C, Do ZN, Hammock BD. 2006. Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett 16(22):5773-7.
  • Inceoglu B, Jinks SL, Schmelzer KR, Waite T, Kim I, Hammock BD. 2006. Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain. Life Sci79(24):2311-2319.
  • Inceoglu B, Lango J, Whetstone P, Hammock BD. 2006. The neutralizing effect of a polyclonal antibody raised against the N-terminal eighteen-aminoacid residues of birtoxin towards the whole venom of Parabuthus transvaalicus. Toxicology47(2):144-149.
  • Jones PD, Tsai H, Do ZN, Morisseau C, Hammock BD. 2006. Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase. Bioorg Med Chem Lett 16(19):5212-5216.
  • Koivunen ME, Dettmer K, Vermeulen R, Bakke B, Gee SJ, Hammock BD. 2006. Improved methods for urinary atrazine mercapturate analysisAssessment of an enzyme-linked immunosorbent assay (ELISA) and a novel liquid chromatographymass spectrometry (LCMS) method utilizing online solid phase extraction (SPE). Anal Chim Acta572(2):180-189.
  • Larsen BT, Miura H, Hatoum OA, Campbell WB, Hammock BD, Zeldin DC, Falck JR, Gutterman DD. 2006. Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BKCa channels: implications for soluble epoxide hydrolase inhibition. American Journal of Pathology290(2):H491-H499.
  • Lee CR, North KE, Bray MS, Fornage M, Seubert JM, Newman JW, Hammock BD, Couper DJ, Heiss G, Zeldin DC. 2006. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Hum Mol Genet15(10):1640-1649.
  • Morisseau C, Newman JW, Tsai H, Baecker PA, Hammock BD. 2006. Peptidyl-urea based inhibitors of soluble epoxide hydrolases. Bioorg Med Chem Lett 16(20):5439-5444.
  • Ng VY, Morisseau C, Falck JR, Hammock BD, Kroetz DL. 2006. Inhibition of Smooth Muscle Proliferation by Urea-Based Alkanoic Acids via Peroxisome Proliferator-Activated Receptor {alpha}Dependent Repression of Cyclin D1. Arteriosclerosis, Thrombosis and Vascular Biology26(11):4262.
  • Nichkova MJ, Dosev D, Perron R, Gee SJ, Hammock BD, Kennedy IM. 2006. Eu3+-doped Gd2O3 nanoparticles as reporters for optical detection and visualization of antibodies patterned by microcontact printing. Anal Bioanal Chem384(3):631-637.
  • Nishi K, Huang H, Kamita SG, Kim I, Morisseau C, Hammock BD. 2006. Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2. Arch Biochem Biophys445(1):115-123.
  • Nording M, Nichkova MJ, Spinnel E, Persson Y, Gee SJ, Hammock BD, Haglund P. 2006. Rapid screening of dioxin-contaminated soil by accelerated solvent extraction/purification followed by immunochemical detection. Anal Bioanal Chem385(2):357-366.
  • Olearczyk JJ, Field MB, Kim I, Morisseau C, Hammock BD, Imig JD. 2006. Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels. Journal of Pharmacology and Experimental Therapeutics318(3):1307-1314.
  • Pokreisz P, Fleming I, Kiss L, Barbosa-Sicard E, Fisslthaler B, Falck JR, Hammock BD, Kim I, Szelid Z, Vermeersch P, Gillijns H, Pellens M, Grimminger F, van Zonneveld A, Collen D, Busse R, Janssens S. 2006. Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling. Hypertension47(4):762-770.
  • Schmelzer KR, Inceoglu B, Kubala L, Kim I, Jinks SL, Eiserich JP, Hammock BD. 2006. Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors. Proceedings of the National Academy of Sciences of the United States of America (USA)103(37):13646-13651.
  • Schmelzer KR, Wheelock AM, Dettmer K, Morin D, Hammock BD. 2006. The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways. Environ Health Perspect 114(9):1354-1360.
  • Seubert JM, Sinal CJ, Graves J, Degraff LM, Bradbury JA, Lee CR, Goralski K, Carey MA, Luria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, Zeldin DC. 2006. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circ Res99(4):442-450.
  • Watanabe T, Schulz D, Morisseau C, Hammock BD. 2006. High-throughput pharmacokinetic method: Cassette dosing in mice. Anal Chim Acta559(1):37-44.
  • Wheelock AM, Miller JL, Miller MJ, Phillips BM, Huntley SA, Gee SJ, Tjeerdema RS, Hammock BD. 2006. Use of carboxylesterase activity to remove pyrethroid-associated toxicity to Ceriodaphnia dubia and Hyalella azteca in toxicity identification evaluations. Environmental Toxicology and Chemistry25(4):973-984.
  • Wolf NM, Morisseau C, Jones PD, Hock B, Hammock BD. 2006. Development of a high-throughput screen for soluble epoxide hydrolase inhibition. Anal Biochem355(1):71-80.
  • Xu D, Li N, He Y, Timofeyev V, Lu L, Tsai H, Kim I, Tuteja D, Mateo RP, Singapuri A, Davis BB, Low R, Hammock BD, Chiamvimonvat N. 2006. Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors. Proceedings of the National Academy of Sciences of the United States of America (USA)103(49):18733-18738.
  • Zhao B, Baston DS, Hammock BD, Denison MS. 2006. Interaction of diuron and related substituted phenylureas with the Ah receptor pathway. J Biochem Mol Toxicol20(3):103-113.

2005

  • Ahn K, Gee SJ, Kim HJ, Nichkova MJ, Hammock BD. 2005. Progress in the development of biosensors for environmental and human monitoring of agrochemicals. Proceedings of the American Chemical Society Pacifichem 966:138-154.
  • Aronov PA, Dettmer K, Christiansen JA, Cornel AJ, Hammock BD. 2005. Development of a HPLC/tandem-MS method for the analysis of the larvicides methoprene, hydroprene and kinoprene at trace levels using Diels-Alder derivatization. J Agric Food Chem53(9):3306-3312.
  • Dorrance AM, Rupp N, Pollock DM, Newman JW, Hammock BD, Imig JD. 2005. An epoxide hydrolase inhibitor, 12-(3-Adamantan-1-yl-ureido)dodecanoic acid (AUDA) reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol 46(6):842-848.
  • Dosev D, Nichkova MJ, Liu M, Guo B, Liu G, Hammock BD, Kennedy IM. 2005. Application of luminescent Eu:Gd2O3 nanoparticles to the visualization of protein micropatterns. J Biomed Opt 10(6):1-7.
  • Dosev D, Nichkova MJ, Liu M, Guo B, Liu G, Xia Y, Hammock BD, Kennedy IM. 2005. Application of fluorescent Eu:Gd2O3 nanoparticles to the visualization of protein micropatterns. Chapter 5699 in: Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals and Applications: III (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, San Jose, CA. pp.473-481.
  • Fang X, Hu S, Watanabe T, Weintraub NL, Snyder GD, Yao J, Liu Y, Shyy JY, Hammock BD, Spector AA. 2005. Activation of Peroxisome Proliferator-Activated Receptor by Substituted Urea-Derived Soluble Epoxide Hydrolase Inhibitors. Journal of Pharmacology and Experimental Therapeutics314(1):260-270.
  • German JB, Hammock BD, Watkins SM. 2005. Metabolomics: building on a century of biochemistry to guide human health. Metabolomics1(1):3-9.
  • Hennebold JD, Mah K, Perez W, Vance JE, Stouffer RL, Morisseau C, Hammock BD, Adashi EY. 2005. Identification and characterization of an ovary-selective isoform of epoxide hydrolase. Biol Reprod72(4):968-975.
  • Huang H, Fleming CD, Nishi K, Redinbo MR, Hammock BD. 2005. Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases. Chem Res Toxicol18(9):1371-1377.
  • Huang H, Stok JE, Stoutamire DW, Gee SJ, Hammock BD. 2005. Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases. Chem Res Toxicol18(3):516-527.
  • Imig JD, Zhao X, Zaharis CZ, Olearczyk JJ, Pollock DM, Newman JW, Kim I, Watanabe T, Hammock BD. 2005. An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension46(4):975-981.
  • Inceoglu B, Lango J, Pessah IN, Hammock BD. 2005. Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. Toxicon45(6):727-733.
  • Jones PD, Wolf NM, Morisseau C, Whetstone P, Hock B, Hammock BD. 2005. Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies. Anal Biochem343(1):66-75.
  • Jung O, Brandes RP, Kim I, Schweda F, Schmidt R, Hammock BD, Busse R, Fleming I. 2005. Soluble epoxide hydrolase is a main effector of angiotensin ll-induced hypertension. Hypertension45(4):759-765.
  • Kang K, Jones PD, Huang H, Zhang R, Mostovich LA, Wheelock CE, Watanabe T, Gulyaeva LF, Hammock BD. 2005. Evaluation of a-cyano ethers as fluorescent substrates for assay of cytochrome P450 enyzme activity. Anal Biochem344(2):183-192.
  • Kim I, Heirtzler FR, Morisseau C, Nishi K, Tsai H, Hammock BD. 2005. Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. J Med Chem48(10):3621-3629.
  • Koivunen ME, Gee SJ, Park E, Lee K, Schenker MB, Hammock BD. 2005. Application of an enzyme-linked immunosorbent assay for the analysis of paraquat in human exposure samples. Arch Environ Contam Toxicol48(2):184-190.
  • Liu Y, Zhang Y, Schmelzer KR, Lee T, Fang X, Zhu Y, Spector AA, Gill S, Morisseau C, Hammock BD, Shyy JY. 2005. The antiinflammatory effect of laminar flow: The role of PPAR, epoxyeicosatrienoic acids, and soluble epoxide hydrolase. Proceedings of the National Academy of Sciences of the United States of America (USA)102(46):16747-16752.
  • Mak SK, Shan G, Lee H, Watanabe T, Stoutamire DW, Gee SJ, Hammock BD. 2005. Development of a class selective immunoassay for the type II pyrethroid insecticides. Anal Chim Acta534:109-120.
  • Morisseau C, Hammock BD. 2005. Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles. Annu Rev Pharmacol Toxicol45:311-333.
  • Newman JW, Morisseau C, Hammock BD. 2005. Epoxide hydrolases: their roles and interactions with lipid metabolism. Prog Lipid Res 44(1):1-50.
  • Nichkova MJ, Dosev D, Gee SJ, Hammock BD, Kennedy IM. 2005. Microarray of immunoassay for phenoxybenzoic acid using polymer encapsulated Eu:Gd2O3 nanoparticles as fluorescent labels. Anal Chem77(21):6864-6873.
  • Nithipatikom K, Endsley MP, Isbell MA, Wheelock CE, Hammock BD, Campbell WB. 2005. A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. Biochem Biophys Res Commun332(4):1028-1033.
  • Schmelzer KR, Kubala L, Newman JW, Kim I, Eiserich JP, Hammock BD. 2005. Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proceedings of the National Academy of Sciences of the United States of America (USA)102(28):9772-9777.
  • Sellers KW, Sun C, Diez-Freire C, Waki H, Morisseau C, Falck JR, Hammock BD, Paton JF, Raizada MK. 2005. Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat. FASEB Journal19:626-628.
  • Shearer GC, Newman JW, Hammock BD, Kaysen GA. 2005. Graded effects of proteinuria on HDL structure in nephrotic rats. Journal of the American Society of Nephrology 16(5):1309-1319.
  • Smith KR, Pinkerton KE, Watanabe T, Pedersen TL, Ma S, Hammock BD. 2005. Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor. Proceedings of the National Academy of Sciences of the United States of America (USA)102(6):2186-2191.
  • Tran KL, Aronov PA, Tanaka H, Newman JW, Hammock BD, Morisseau C. 2005. Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase. Biochemistry44(36):12179-12187.
  • Wheelock CE, Eder KJ, Werner I, Huang H, Jones PD, Brammell BF, Elskus AA, Hammock BD. 2005. Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos. Aquatic Toxicology74(2):172-192.
  • Wheelock CE, Miller JL, Miller MJ, Phillips BM, Gee SJ, Tjeerdema RS, Hammock BD. 2005. Influence of container adsorption upon observed pyrethroid toxicity to Ceriodaphnia dubia and Hyalella azteca. Aquatic Toxicology74(1):47-52.

2004

  • Ahn K, Watanabe T, Gee SJ, Hammock BD. 2004. Hapten and antibody production for a sensitive immunoassay determinining a human urinary metabolite of the pyrethroid insecticide permethrin. J Agric Food Chem52(15):4583-4594.
  • Denison MS, Rogers WJ, Bohonowych JE, Zhao B, Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. 2004. Promiscuous ligand-dependent activation of the Ah receptor: chemicals in crude extracts from commercial and consumer products bind to and activate the Ah receptor and Ah receptor-dependent gene expression. Organohalogen Compounds 66:2966-2971.
  • Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. 2004. Altered Kidney CYP2C and Cyclooxygenase-2 Levels Are Associated with Obesity-Related Albuminuria. Obesity12(8):1278-1289. doi:10.1038/oby.2004.162
  • DuTeaux SB, Newman JW, Morisseau C, Fairbairn EA, Jelks K, Hammock BD, Miller MG. 2004. Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism. Toxicological Sciences78(2):187-195.
  • Fang X, Weintraub NL, McCaw RB, Hu S, Harmon S, Rice JB, Hammock BD, Spector AA. 2004. Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels. American Journal of Physiology - Cell Physiology287:H2412-H2420.
  • Gomez GA, Morisseau C, Hammock BD, Christianson DW. 2004. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry43(16):4716-4723.
  • Kennedy IM, Koivunen ME, Gee SJ, Cummins CM, Perron R, Dosev D, Hammock BD. 2004. Nanoscale fluoro-immuno assays with lanthanide oxide nanoparticles. Chapter 5593 in: Nanosensing: Materials and Devices (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, Bellingham, WA. pp.329-339.
  • Kim I, Morisseau C, Watanabe T, Hammock BD. 2004. Design, Synthesis, and Biological Activity of 1,3-Disubstituted Ureas as Potent Inhibitors of the Soluble Epoxide Hydrolase of Increased Water Solubility. J Med Chem47(8):759-765.
  • Lee H, Shan G, Ahn K, Park E, Watanabe T, Gee SJ, Hammock BD. 2004. Development of an enzyme-linked Immunosorbent assay for the pyrethroid cypermethrin. J Agric Food Chem52(2):1039-1043.
  • Newman JW, Stok JE, Vidal JD, Corbin CJ, Huang Q, Hammock BD, Conley AJ. 2004. Cytochrome P450-dependent lipid metabolism in preovulatory follicles. Endocrinology145(11):5097-5105.
  • Nichkova MJ, Park E, Koivunen ME, Kamita SG, Gee SJ, Chuang J, Van Emon JM, Hammock BD. 2004. Immunochemical determination of dioxins in environmental and biological samples. Talanta63:1213-1223.
  • Park E, Kim J, Gee SJ, Watanabe T, Ahn K, Hammock BD. 2004. Determination of pyrethroid residues in agricultural products by an enzyme-linked immunosorbent assay. J Agric Food Chem52(18):5572-5576.
  • Rufo C, Hammock BD, Gee SJ, Last JA, Gonzalez-Sapienza GG. 2004. Robust and sensitive monoclonal enzyme-linked immunosorbent assay for the herbicide molinate. J Agric Food Chem52(2):182-187.
  • Seubert JM, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman JW, Mao L, Rockman HA, Hammock BD, Murphy E, Zeldin DC. 2004. Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K+ Channels and p42/p44 MAPK Pathway. Circ Res95(5):506-514.
  • Shan G, Huang H, Stoutamire DW, Gee SJ, Leng G, Hammock BD. 2004. A sensitive class specific immunoassay for the detection of pyrethroid metabolites in human urine. Chem Res Toxicol17(2):218-225.
  • Stok JE, Goloshchapov A, Song C, Wheelock CE, Derbel M, Morisseau C, Hammock BD. 2004. Investigation of the role of a second conserved serine in carboxylesterases via site-directed mutagenesis. Arch Biochem Biophys430(2):247-255.
  • Stok JE, Huang H, Jones PD, Wheelock CE, Morisseau C, Hammock BD. 2004. Identification, expression and purification of a pyrethroid hydrolyzing carboxylesterase from mouse liver microsomes. Journal of Biological Chemistry279(28):29863-29869.
  • Wheelock CE, Miller JL, Miller MJ, Gee SJ, Shan G, Hammock BD. 2004. Development of toxicity identification evaluation procedures for pyrethroid detection using esterase activity. Environmental Toxicology and Chemistry23(11):2699-2708.
  • Yu Z, Davis BB, Morisseau C, Hammock BD, Olson JL, Kroetz DL, Weiss RH. 2004. Vascular localization of soluble epoxide hydrolase in the human kidney. American Journal of Physiology - Renal Physiology286(4):F720-F726.
  • Zhao X, Yamamoto T, Newman JW, Kim I, Watanabe T, Hammock BD, Stewart J, Imig JD. 2004. Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. Journal of the American Society of Nephrology 15(5):1244-53.

2003

  • Chen S, Yuen P, Collins SD, Smith R, Koivunen ME, Hammock BD. 2003. Time gated detection of europium nanoparticles in a microchannel-based environmental immunoassay. In: Proceedings of SPIE (The International Society for Optical Engineering).
  • Cho YA, Kim Y, Hammock BD, Lee YT, Lee H. 2003. Development of a microtiter plate ELISA and a dipstick ELISA for the determination of the organophosphorus insecticide fenthion. J Agric Food Chem51(27):7854-7860.
  • Denton DL, Wheelock CE, Murray SA, Deanovic LA, Hammock BD, Hinton DE. 2003. Joint acute toxicity of esfenvalerate and diazinon to fathead minnow (Pimephales promelas) larvae. Environmental Toxicology and Chemistry22(2):336-341.
  • Feng J, Mack JS, Shan G, Hammock BD. 2003. C60 nanoparticle quenching used as a biological label. In: Proceedings of SPIE (The International Society for Optical Engineering). pp.156-163.
  • Feng J, Shan G, Hammock BD, Kennedy IM. 2003. Fluorescence quenching competitive immunoassay in micro droplets. Biosens Bioelectron18(8):1055-1063.
  • Feng J, Shan G, Maquieira A, Koivunen ME, Guo B, Hammock BD. 2003. Functionalized Europium Oxide Nanoparticles Used as a Fluorescent Label in an Immunoassay for Atrazine. Anal Chem75(19):5282-5286.
  • Inceoglu B, Lango J, Jing J, Chen L, Doymaz F, Pessah IN, Hammock BD. 2003. One scorpion, two venoms: Prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action. Proceedings of the National Academy of Sciences of the United States of America (USA)100(3):922-927.
  • Kim Y, Cho YA, Lee H, Lee YT, Gee SJ, Hammock BD. 2003. Synthesis of haptens for immunoassay of organophosphorus pesticides and effect of heterology in hapten spacer arm length of immunoassay sensitivity. Anal Chim Acta475(1-2):85-96.
  • Koivunen ME, Morisseau C, Newman JW, Horwath WR, Hammock BD. 2003. Purification and characterization of a methylene urea-hydrolyzing enzyme from Rhizobium radiobacter (Agrobacterium tumefaciens). Soil Biology and Biochemistry35(11):1433-1442.
  • Lee H, Watanabe T, Gee SJ, Hammock BD. 2003. Application of an Enzyme-Linked Immunosorbent Assay (ELISA) to Determine Deltamethrin Residues in Milk. Bull Environ Contam Toxicol71(1):14-20.
  • Lee JK, Ahn K, Stoutamire DW, Gee SJ, Hammock BD. 2003. Development of an Enzyme-Linked Immunosorbent Assay for the Detection of the Organophosphorus Insecticide Acephate. J Agric Food Chem51(13):3695-3703.
  • McElroy NR, Jurs PC, Morisseau C, Hammock BD. 2003. QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds. J Med Chem46(6):1066-1080.
  • Morisseau C, Hammock BD. 2003. Measurements of soluble epoxide hydrolase (sEH) activity. Chapter 4 in: Current Protocals in Toxicology. John Wiley & Sons, NY. pp.1-4.
  • Newman JW, Morisseau C, Harris TR, Hammock BD. 2003. The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. Proceedings of the National Academy of Sciences of the United States of America (USA)100(4):1558-1563.
  • Nichkova MJ, Feng J, Sanchez-Baeza F, Marco M, Hammock BD, Kennedy IM. 2003. Competitive quenching fluorescence immunoassy for chlorophenols based on laser-induced fluorescence detection in microdroplets. Anal Chem75(1):83-90.
  • Przybyla-Zawislak BD, Srivastava PK, Vazquez-Matias J, Mohrenweiser HW, Maxwell JE, Hammock BD, Bradbury JA, Enayetallah AE, Zeldin DC, Grant DF. 2003. Polymorphisms in human soluble epoxide hydrolase. Mol Pharmacol64(2):482-490.
  • Szekacs A, Le HM, Szurdoki F, Hammock BD. 2003. Optimization and validation of an enzyme immunoassay for the insect growth regulator fenoxycarb. Anal Chim Acta487(1):15-29.
  • Taniai K, Inceoglu AB, Yukuhiro K, Hammock BD. 2003. Characterization and cDNA cloning of a clofibrate-inducible microsomal epoxide hydrolase in Drosophila melanogaster. FEBS Journal 270(23):4696-4705.
  • Viswanathan S, Hammock BD, Newman JW, Meerarani P, Toborek M, Hennig B. 2003. Involvement of CYP 2C9 in Mediating the Proinflammatory Effects of Linoleic Acid in Vascular Endothelial Cells. J Am Coll Nutr22(6):502-510.
  • Watanabe T, Morisseau C, Newman JW, Hammock BD. 2003. In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecy1-urea. Drug Metabolism and Disposition31(7):846-853.
  • Wheelock CE, Nakagawa Y, Akamatsu M, Hammock BD. 2003. Use of classical and 3-D QSAR to examine the hydration state of juvenile hormone esterase inhibitors. Bioorg Med Chem11(23):5101-5116.
  • Wheelock CE, Wheelock AM, Zhang RH, Stok JE, Morisseau C, Le Valley SE, Green CE, Hammock BD. 2003. Evaluation of alpha-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes. Anal Biochem315(2):208-222.
  • Zhang RH, Kang K, Shan G, Hammock BD. 2003. Design, synthesis and evaluation of novel P450 fluorescent probes bearing -cyanoether. Tetrahedron Lett44(23):4331-4334.

2002

  • Cho YA, Lee H, Park EY, Lee YT, Hammock BD, Ahn K, Lee JK. 2002. Development of an ELISA for the organophosphorus insecticide chlorpyrifos. Bulletin of the Korean Chemical Society 23(3):481-487.
  • Davis BB, Thompson DA, Howard LL, Morisseau C, Hammock BD, Weiss RH. 2002. Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proceedings of the National Academy of Sciences of the United States of America (USA)99(4):2222-2227.
  • Dedos SG, Szurdoki F, Szekacs A, Shiotsuki T, Hammock BD, Shimada J, Fugo H. 2002. Fenoxycarb levels and their effects on general and juvenile hormone esterase activity in the hemolymph of the silkworm, Bombyx mori. Pestic Biochem Physiol 73(3):174-187.
  • Denison MS, Nagy SR, Ziccardi MH, Clark GC, Chu MD, Brown DJ, Shan G, Sugawara Y, Gee SJ, Sanborn JR, Hammock BD. 2002. Bioanalytical approaches for the detection of dioxin and related halogenated aromatic hydrocarbons. In: Biomarkers of Environmentally Associated Disease: Technologies, Concepts, and Perspectives. CRC Press Company, Boca Raton, FL. pp.483-494.
  • Fang X, Weintraub NL, Oltman CL, Stoll LL, Kaduce TL, Harmon S, Dellsperger KC, Morisseau C, Hammock BD, Spector AA. 2002. Human coronary endothelial cells convert 14, 15-EET to a biologically active chain-shortened epoxide. American Journal of Physiology - Heart and Circulatory Physiology283(6):H2306-H2314.
  • Feng J, Shan G, Hammock BD, Kennedy IM. 2002. Fluorescence quenching competitive fluoroimmunoassay in micro droplets. In: Methods for Ultrasensitive Detection II, Proceedings of the International Society for Optical Engineering. SPIE, Bellingham, WA. pp.118-127.
  • Fornage M, Hinojos CA, Nurowska BW, Boerwinkle E, Hammock BD, Morisseau C, Doris PA. 2002. Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats. Hypertension40(4):485-490.
  • Harcourt RL, Horne I, Sutherland TD, Hammock BD, Russell RJ, Oakeshott JG. 2002. Development of a simple and sensitive fluorimetric method for isolation or coumaphos-hydrolysing bacteria. Lett Appl Microbiol34(4):263-268.
  • Hennig B, Hammock BD, Slim RM, Toborek M, Viswanathan S, Robertson LW. 2002. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. Int J Hyg Environ Health205(1-2):95-102.
  • Imig JD, Zhao X, Capdevila JH, Morisseau C, Hammock BD. 2002. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension. Hypertension39(2):690-694.
  • Inceoglu B, Hayashida Y, Lango J, Ishida AT, Hammock BD. 2002. A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus. FEBS Journal 269(22):5369-5376.
  • Kim K, Kim Y, Lee YT, Hammock BD, Lee H. 2002. Development of an enzyme-linked immunosorbent assay for the organophosphorus insecticide bromophos-ethyl. J Agric Food Chem50(23):6675-6682.
  • Lee H, Shan G, Watanabe T, Stoutamire DW, Gee SJ, Hammock BD. 2002. Enzyme-linked immunosorbent assay for the pyrethroid deltamethrin. J Agric Food Chem50(20):5526-5532.
  • Leppert VJ, Harvey AS, McCool GD, Quinlan FT, Feng J, Shan G, Stroeve P, Risbud SH, Hammock BD, Kennedy IM. 2002. Long-wavelength emitting nanocrystals for bioassay applications. In: Nanoscale Optics and Applications. Proceedings of SPIE, pp.110-121.
  • Morisseau C, Goodrow MH, Newman JW, Wheelock CE, Dowdy DL, Hammock BD. 2002. Structural refinement of inhibitors of urea based soluble epoxide hydrolases. Biochem Pharmacol63(9):1599-1608.
  • Morisseau C, Hammock BD. 2002. Epoxide Hydrolases. In: Wiley Encyclopedia of Molecular Medicine. Medicine John Wiley & Sons Inc., New York, NY. pp.1194-1197.
  • Nagy SR, Sanborn JR, Hammock BD, Denison MS. 2002. Development of a green fluorescent protein based cell bioassay for the rapid and inexpensive detection and characterization of AhR agonists. Toxicological Sciences65(2):200-210.
  • Newman JW, Watanabe T, Hammock BD. 2002. The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS. J Lipid Res43(9):1563-1578.
  • Park WC, Cho YA, Kim Y, Hammock BD, Lee YT, Lee H. 2002. Development of an enzyme-linked immunosorbent assay for the organophosphorus insecticide bromophos. Bulletin of the Korean Chemical Society 23(10):1399-1403.
  • Severson T, Goodrow MH, Morisseau C, Dowdy DL, Hammock BD. 2002. Urea and amide-based inhibitors of the juvenile hormone epoxide hydrolase of the tobacco hornworm(Manduca sexta: Sphingidae). Insect Biochem Mol Biol 32:1741-1756.
  • Shelver WL, Shan G, Gee SJ, Stanker LH, Hammock BD. 2002. Comparison of immunoaffinity column recovery patterns of polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans on columns generated with different monoclonal antibody clones and polyclonal antibodies. Anal Chim Acta457:199-209.
  • Sugawara Y, Saito K, Ogawa M, Kobayashi S, Shan G, Sanborn JR, Hammock BD, Nakazawa H, Matsuki Y. 2002. Development of dioxin toxicity evaluation method in human milk by enzyme-linked immunosorbent assay--assay validation for human milk. Chemosphere46(9-10):1471-1476.
  • Szurdoki F, Szekacs A, Le HM, Hammock BD. 2002. Synthesis of haptens and protein conjugates for the development of immunoassays for the insect growth regulator fenoxycarb. J Agric Food Chem50(1):29-40.
  • Viswanathan S, Hammock BD, Meerarani P, Toborek M, Hennig B. 2002. Mechanisms of linoleic acid-induced endothelial activation: possible involvement of epoxide metabolites in mediating the inflammatory response. FASEB Journal16:A157.
  • Wheelock CE, Colvin ME, Uemura I, Olmstead MM, Sanborn JR, Nakagawa Y, Jones AD, Hammock BD. 2002. Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors. J Med Chem45(25):5576-5593.
  • Zurek G, Gee SJ, Hammock BD. 2002. Development of an enzyme immunoassay for linoleic acid diols in urine. Anal Chim Acta466(2):247-256.

2001

  • Buchholz BA, Vogel JS, Gilman DS, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. 2001. Determining an occupational dermal exposure biomarker for atrazine through measurement of metabolites in human urine by HPLC-accelerator mass spectrometry. In: Toxicology of Skin. Taylor & Francis, Philadelphia, PA. pp.145-157.
  • Fang X, Kaduce TL, Weintraub NL, Harmon S, Teesch LM, Morisseau C, Thompson DA, Hammock BD, Spector AA. 2001. Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells: Implications for the vascular effects of soluble epoxide hydrolase inhibition. Journal of Biological Chemistry276(18):14867-14874.
  • Hennig B, Slim RM, Toborek M, Hammock BD, Robertson LW. 2001. Cardiovascular disease: endothelial cells as a target for PCB toxicity. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.211-220.
  • Hennig B, Viswanathan S, Toborek M, Hammock BD. 2001. Mechanisms of fatty-acid mediated endothelial cell activation. J Am Coll Nutr20:574.
  • Huang Q, Deveraux QL, Maeda S, Stennicke HR, Hammock BD, Reed JC. 2001. Cloning and characterization of an inhibitor of apoptosis protein (IAP) from Bombyx mori. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research1499(3):191-198.
  • Inceoglu B, Lango J, Wu J, Hawkins P, Southern J, Hammock BD. 2001. Isolation and characterization of a novel type of neurotoxic peptide from the venom of the South African scorpion Parabuthus transvaalicus (Buthidae). FEBS Journal 268(20):5407-5413.
  • Lee JK, Ahn K, Park OS, Kang SY, Hammock BD. 2001. Development of an ELISA for the detection of the residues of the insecticide imidacloprid in agricultural and environmental samples. J Agric Food Chem49(5):2159-2167.
  • Matveeva EG, Gribkova EV, Sanborn JR, Gee SJ, Hammock BD, Savitsky AP. 2001. Development of a homogeneous phosphorescent immunoassay for the detection of polychlorinated dibenzo-p-dioxins. Analytical Letters 34(13):2311-2320.
  • Matveeva EG, Shan G, Kennedy IM, Gee SJ, Hammock BD. 2001. Homogeneous fluoroimmunoassay of a pyrethroid metabolite in urine. Anal Chim Acta444:103-117.
  • Miyashita M, Presley JM, Buchholz BA, Lam KS, Lee YM, Vogel JS, Hammock BD. 2001. Attomole level protein sequencing by Edman degradation coupled with accelerator mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America (USA)98(8):4403-4408.
  • Morisseau C, Newman JW, Dowdy DL, Goodrow MH, Hammock BD. 2001. Inhibition of microsomal epoxide hydrolases by ureas, amides and amines. Chem Res Toxicol14(4):409-415.
  • Newman JW, Denton DL, Morisseau C, Koger CS, Wheelock CE, Hinton DE, Hammock BD. 2001. Evaluation of fish models of soluble epoxide hydrolase inhibition. Environ Health Perspect 109(1):61-66. PMCID:PMC1242052
  • Newman JW, Hammock BD. 2001. Optimized thiol derivatizing reagent for the mass spectral analysis of disubstituted epoxy fatty acids. Journal of Chromatography A925(1-2):223-240.
  • Shan G, Hammock BD. 2001. Development of sensitive esterase assays based on alpha-cyano-containing esters. Anal Biochem299(1):54-62.
  • Shan G, Leeman WR, Gee SJ, Sanborn JR, Jones AD, Chang DP, Hammock BD. 2001. Highly sensitive dioxin immunoassay and its application to soil and biota samples. Anal Chim Acta444:169-178.
  • Sisemore MF, Zheng J, Yang JC, Thompson DA, Plopper CG, Cortopassi GA, Hammock BD. 2001. Cellular characterization of leukotoxin diol-induced mitochondrial dysfunction. Arch Biochem Biophys392(1):32-37.
  • Slim RM, Hammock BD, Toborek M, Robertson LW. 2001. The role of methyl linoleic acid epoxide and diol metabolites in the synergistic toxicity of linoleic acid and PCBs to vascular endothelial cells. Toxicological Sciences60:13.
  • Slim RM, Hammock BD, Toborek M, Robertson LW, Newman JW, Morisseau C, Watkins BA, Viswanathan S, Hennig B. 2001. The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. Toxicol Appl Pharmacol171(3):184-193.
  • Staimer N, Gee SJ, Hammock BD. 2001. Development of a class-selective enzyme immunoassay for urinary phenolic glucuronides. Anal Chim Acta444:27-36.
  • Staimer N, Gee SJ, Hammock BD. 2001. Development of a sensitive enzyme immunoassay for the detection of phenyl-b-D-thioglucuronide in human urine. Fresenius J Anal Chem369(3-4):273-279.
  • Viswanathan S, Narayan P, Hammock BD, Meerarani P, Toborek M, Hennig B. 2001. Linoleic acid-derived epoxides alter calcium and nitric oxide metabolism in endothelial cells. FASEB Journal15:A190.
  • Watanabe T, Hammock BD. 2001. Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high performance liquid chromatography with electrospray tandem mass spectrometry. Anal Biochem299(2):227-234.
  • Watanabe T, Shan G, Stoutamire DW, Gee SJ, Hammock BD. 2001. Development of a class-specific immunoassay for the type I pyrethroid insecticides. Anal Chim Acta444:119-129.
  • Watkins SM, Hammock BD, Newman JW, German JB. 2001. Individual metabolism should guide agriculture toward foods for improved health and nutrition. American Journal of Clinical Nutrition74(3):283-286.
  • Wheelock CE, Severson T, Hammock BD. 2001. Synthesis of new carboxylesterase inhibitors and evaluation of potency and water solubility. Chem Res Toxicol14(12):1563-1572.
  • Wudayagiri R, Inceoglu B, Herrmann R, Derbel M, Choudary P, Hammock BD. 2001. Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus. BMC Biochem2:16.
  • Zheng J, Plopper CG, Lakritz J, Storms DH, Hammock BD. 2001. Leukotoxin-diol - A putative toxic mediator involved in acute respiratory distress syndrome. Am J Respir Cell Mol Biol25(4):434-438.

2000

  • Argiriadi MA, Morisseau C, Goodrow MH, Dowdy DL, Hammock BD, Christianson DW. 2000. Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation. Journal of Biological Chemistry275(20):15265-15270.
  • Draper AJ, Hammock BD. 2000. Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. Arch Biochem Biophys376(1):199-205.
  • Fanucchi MV, Buckpitt AR, Murphy M, Storms DH, Hammock BD, Plopper CG. 2000. Development of phase II xenobiotic metabolizing enzymes in differentiating murine Clara cells. Toxicol Appl Pharmacol168(3):253-267.
  • Greene JF, Newman JW, Williamson K, Hammock BD. 2000. Toxicity of epoxy fatty acids and related compounds to cells expressing human soluble epoxide hydrolase. Chem Res Toxicol13(4):217-226.
  • Greene JF, Williamson K, Newman JW, Morisseau C, Hammock BD. 2000. Metabolism of monoepoxides of methyl linoleate: bioactivation and detoxification. Arch Biochem Biophys376(2):420-432.
  • Greene JF, Zheng J, Grant DF, Hammock BD. 2000. Cytotoxicity of 1,2-epoxynaphthalene is correlated with protein binding and in situ glutathione depletion in cytochrome P4501A1 expressing Sf-21 cells. Toxicological Sciences53(2):352-360.
  • Huang Q, Deveraux QL, Maeda S, Salvesen GS, Stennicke HR, Hammock BD, Reed JC. 2000. Evolutionary conservation of apoptosis mechanisms: Lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9. Proceedings of the National Academy of Sciences of the United States of America (USA)97:1427-1432.
  • Kido H, Maquieira A, Hammock BD. 2000. Disc-based immunoassay microarrays. Anal Chim Acta411(1-2):1-11.
  • Lakritz J, Winder BS, Noorouz-Zadeh J, Huang TL, Buckpitt AR, Hammock BD, Plopper CG. 2000. Hepatic and pulmonary enzyme activities in horses. Am J Vet Res61(2):152-157.
  • Lohse C, Jaeger LL, Staimer N, Sanborn JR, Jones AD, Lango J, Gee SJ, Hammock BD. 2000. Development of a class selective enzyme-linked immunosorbent assay for mercapturic acids in human urine. J Agric Food Chem48(12):5913-5923.
  • Morisseau C, Beetham JK, Pinot F, Debernard S, Newman JW, Hammock BD. 2000. Cress and potato soluble epoxide hydrolases: Purification, biochemical characterization, and comparison to mammalian enzymes. Arch Biochem Biophys378(2):321-332.
  • Nakagawa Y, Wheelock CE, Morisseau C, Goodrow MH, Hammock BG, Hammock BD. 2000. 3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues. Bioorg Med Chem8(11):2663-2673.
  • Shan G, Huang W, Gee SJ, Buchholz BA, Vogel JS, Hammock BD. 2000. Isotope-labeled immunoassays without radiation waste. Proceedings of the National Academy of Sciences of the United States of America (USA)97(6):2445-2449.
  • Shan G, Leeman WR, Stoutamire DW, Gee SJ, Chang DP, Hammock BD. 2000. Enzyme-linked immunosorbent assay for the pyrethroid permethrin. J Agric Food Chem48(9):4032-4040.
  • Shan G, Sanborn JR, Gilman DS, Nagy SR, Gee SJ, Stoutamire DW, Mercer RS, Jones AD, Stanker LH, Denison MS, Hammock BD. 2000. Surrogates for dioxin analyses: analytical, ELISA and toxicological aspects. Organohalogen Compounds 45:188-191.
  • Williamson K, Morisseau C, Maxwell JE, Hammock BD. 2000. Regio- and enantioselective hydrolysis of phenyloxiranes catalyzed by soluble epoxide hydrolase. Tetrahedron: Asymmetry11:4451-4462.
  • Yamada T, Morisseau C, Maxwell JE, Argiriadi MA, Christianson DW, Hammock BD. 2000. Biochemical evidence for the involvement of tyrosine in epoxide activation during the catalytic cycle of epoxide hydrolase. Journal of Biological Chemistry275(30):23082-23088.
  • Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC, Kroetz DL. 2000. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circ Res87(11):992-998.

1999

  • Argiriadi MA, Morisseau C, Hammock BD, Christianson DW. 1999. Detoxification of environmental mutagens and carcinogens: Structure, mechanism, and evolution of liver epoxide hydrolase. Proceedings of the National Academy of Sciences of the United States of America (USA)96:10637-10642.
  • Buchholz BA, Fultz E, Haack KW, Vogel JS, Gilman DS, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. 1999. HPLC-accelerator MS measurement of atrazine metabolites in human urine after dermal exposure. Anal Chem71(16):3519-3525.
  • Draper AJ, Hammock BD. 1999. Inhibition of soluble and microsomal epoxide hydrolase by zinc and other metals. Toxicological Sciences52:26-32.
  • Draper AJ, Hammock BD. 1999. Soluble epoxide hydrolase in rat inflammatory cells is indistinguishable from soluble epoxide hydrolase in rat liver. Toxicological Sciences50:30-35.
  • Kido H, Szurdoki F, Gustin MS, Hammock BD. 1999. Chelate sensor method for mercury. In: Metals and Genetics. Kluwer Academic/Plenum Press, NY. pp.235-259.
  • Morisseau C, Derbel M, Lane TR, Stoutamire DW, Hammock BD. 1999. Differential induction of hepatic drug-metabolizing enzymes by fenvaleric acid in male rats. Toxicological Sciences52(2):148-153.
  • Morisseau C, Goodrow MH, Dowdy DL, Zheng J, Greene JF, Sanborn JR, Hammock BD. 1999. Potent urea and carbamate inhibitors of soluble epoxide hydrolases. Proceedings of the National Academy of Sciences of the United States of America (USA)96(16):8849-8854.
  • Morisseau C, Ward BL, Gilchrist DG, Hammock BD. 1999. Multiple epoxide hydrolases in Alternaria alternata f. sp. lycopersici and their relationship to medium composition and host-specific toxin production. Appl Environ Microbiol65(6):2388-2395.
  • Mullen RT, Trelease RN, Duerk H, Arand M, Hammock BD, Oesch F, Grant DF. 1999. Differential subcellular localization of endogenous and transfected soluble epoxide hydrolase in mammalian cells: evidence for isozyme variants. FEBS Lett445(2-3):301-305.
  • Shan G, Stoutamire DW, Gee SJ, Wengatz I, Hammock BD. 1999. Development of an immunoassay for the pyrethroid insecticide esfenvalerate. J Agric Food Chem47(5):2145-2155.
  • Shan G, Wengatz I, Stoutamire DW, Gee SJ, Hammock BD. 1999. An enzyme-linked immunosorbent assay for the detection of esfenvalerate metabolites in human urine. Chem Res Toxicol12(11):1033-1041.
  • Thomas BA, Church WB, Lane TR, Hammock BD. 1999. Homology model of juvenile hormone esterase from the crop pest, Heliothis virescens. Proteins: Structure, Function, and Genetics 34(2):184-196.
  • Yazynina EV, Zherdev AV, Dzantiev BB, Izumrudov VA, Gee SJ, Hammock BD. 1999. Immunoassay techniques for detection of the herbicide simazine based on use of oppositely charged water-soluble polyelectrolytes. Anal Chem71(16):3538-3543.
  • Yazynina EV, Zherdev AV, Dzantiev BB, Izumrudov VA, Gee SJ, Hammock BD. 1999. Microplate immunoassay technique using polyelectrolyte carriers: kinetic studies and application to detection of the herbicide atrazine. Anal Chim Acta399(1-2):151-160.

1998

  • Gilman DS, Gee SJ, Hammock BD, Vogel JS, Haack KW, Buchholz BA, Freeman SP, Wester RC, Hui X, Maibach HI. 1998. Analytical performance of accelerator mass spectrometry and liquid scintillation counting for detection of 14C-labeled atrazine metabolites in human urine. Anal Chem70(16):3463-3469.
  • Goodrow MH, Hammock BD. 1998. Hapten design for compound-selective antibodies: ELISA's for environmentally deleterious small molecules. Anal Chim Acta376(1):83-91.
  • Harris AS, Wengatz I, Wortberg M, Kreissig SB, Gee SJ, Hammock BD. 1998. Development and application of immunoassays for biological and environmental monitoring. In: Effects of Multiple Impacts on Ecosystems. Lewis Publishers, Chelsea, MI. pp.135-153.
  • Jaeger LL, Jones AD, Hammock BD. 1998. Development of an enzyme-linked immunosorbent assay for atrazine mercapturic acid in human urine. Chem Res Toxicol11(4):342-352. doi:10.1021/tx9701844
  • Marco M, Gee SJ, Hammock BD. 1998. Determination of 1-naphthol in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C.9.1-2C.9.11.
  • Marco M, Gee SJ, Hammock BD. 1998. Determination of carbaryl in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C8.1-2C8.15.
  • Mitchell AE, Zheng J, Hammock BD, Lo Bello M, Jones AD. 1998. Structural and functional consequences of haloenol lactone inactivation of murine and human glutathione S-transferase. Biochemistry37(19):6752-6759.
  • Reimer GJ, Gee SJ, Hammock BD. 1998. Comparison of a time-resolved fluorescence immunoassay and an enzyme-linked immunosorbent assay for the analysis of atrazine in water. J Agric Food Chem46(8):3353-3358.
  • Sanborn JR, Gee SJ, Gilman DS, Sugawara Y, Jones AD, Rogers JM, Szurdoki F, Stanker LH, Stoutamire DW, Hammock BD. 1998. Hapten synthesis and antibody development for polychlorinated dibenzo-p-dioxin immunoassays. J Agric Food Chem46:2407-2416.
  • Sugawara Y, Gee SJ, Sanborn JR, Gilman DS, Hammock BD. 1998. Development of a highly sensitive enzyme-linked immunosorbent assay based on polyclonal antibodies for the detection of polychlorinated dibenzo-p-dioxins. Anal Chem70(6):1092-1099.
  • Wengatz I, Stoutamire DW, Gee SJ, Hammock BD. 1998. Development of an enzymelinked immunosorbent assay for the detection of the pyrethroid insecticide fenpropathrin. J Agric Food Chem46(6):2211-2221.

1997

  • Jones G, Wortberg M, Rocke DM, Hammock BD. 1997. Immunoassay of cross-reacting analytes. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.331-342.
  • Kido H, Goodrow MH, Griffeth V, Lucas AD, Gee SJ, Hammock BD. 1997. Development of an enzyme-linked immunosorbent assay for the detection of hydroxytriazines. J Agric Food Chem45(2):414-424.
  • Moghaddam MF, Grant DF, Cheek JM, Greene JF, Williamson K, Hammock BD. 1997. Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase. Nat Med3(5):562-566.
  • Schutz S, Wengatz I, Goodrow MH, Gee SJ, Hummel HE, Hammock BD. 1997. Development of an enzyme-linked-immunosorbent assay for azadirachtins. J Agric Food Chem45(6):2363-2368.
  • Swamy AR, Danesvar MI, Evans, III L, Strekowski L, Narayanan N, Szurdoki F, Wengatz I, Hammock BD, Patonay G. 1997. Near-infrared fluorescent immunoassays: A novel approach to environmental analysis. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.141-161.
  • Szurdoki F, Kido H, Hammock BD. 1997. Rapid mercury assays. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.38-48.
  • Zheng J, Cho M, Jones AD, Hammock BD. 1997. Evidence of quinone metabolites of naphthalene covalently bound to sulfur nucleophiles of proteins of murine clara cells after exposure to naphthalene. Chem Res Toxicol10(9):1008-1014.

1996

  • Grant DF, Greene JF, Pinot F, Borhan B, Moghaddam MF, Hammock BD, McCutchen B, Ohkawa H, Luo G, Guenthner TM. 1996. Development of an in situ toxicity assay system using recombinant baculoviruses. Biochem Pharmacol51(4):503-515.
  • Jones G, Wortberg M, Hammock BD, Rocke DM. 1996. A procedure for the immunoanalysis of samples containing one or more members of a group of cross-reacting analytes. Anal Chim Acta336(1-3):175-183.
  • Jones G, Wortberg M, Kreissig SB, Hammock BD, Rocke DM. 1996. Application of the bootstrap to calibration experiments. Anal Chem68(5):763-770.
  • Linde CD, Gee SJ, Goh KS, Hsu JC, Hammock BD, Barry TA, Weaver DJ. 1996. Regulatory application of ELISA: Compliance monitoring of bromacil in soil. Bull Environ Contam Toxicol57(2):264-269.
  • Szurdoki F, Jaeger LL, Harris AS, Kido H, Wengatz I, Goodrow MH, Szekacs A, Wortberg M, Zheng J, Stoutamire DW, Sanborn JR, Gilman DS, Jones AD, Gee SJ, Choudary P, Hammock BD. 1996. Rapid assays for environmental and biological monitoring. Journal of Environmental Science and Health31(3):451-458.
  • Wengatz I, Harris AS, Gilman DS, Wortberg M, Kido H, Szurdoki F, Goodrow MH, Jaeger LL, Stoutamire DW, Sanborn JR, Gee SJ, Hammock BD. 1996. Recent developments in immunoassays and related methods for the detection of xenobiotics. In: Environmental Immunochemical Methods, Perspectives and Applications. ACS Symposium Series No. 646, American Chemical Society, Washington, DC. pp.110-126.
  • Wortberg M, Goodrow MH, Gee SJ, Hammock BD. 1996. Immunoassay for simazine and atrazine with low cross-reactivity for propazine. J Agric Food Chem44(8):2210-2219.
  • Wortberg M, Jones G, Kreissig SB, Rocke DM, Gee SJ, Hammock BD. 1996. An approach to the construction of an immunoarray for differentiating and quantitating cross reacting analytes. Anal Chim Acta319(3):291-303.
  • Zheng J, Hammock BD. 1996. Development of polyclonal antibodies for detection of protein modification by 1,2-naphthoquinone. Chem Res Toxicol9(5):904-909.
  • Zheng J, Mitchell AE, Jones AD, Hammock BD. 1996. Haloenol lactone is a new isozyme-selective and active site-directed inactivator of glutathione S-transferase. Journal of Biological Chemistry271(34):20421-20425.

1995

  • Borhan B, Jones AD, Pinot F, Grant DF, Kurth M, Hammock BD. 1995. Mechanism of soluble epoxide hydrolase. Formation of An a-hydroxy ester-enzyme intermediate through Asp-333. Journal of Biological Chemistry270(45):26923-26930.
  • Choudary P, Lee HA, Hammock BD, Morgan MR. 1995. Recombinant antibodies: New tools for immunoassays. Chapter 13 in: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.171-185.
  • Gee SJ, Hammock BD, Skerritt JH. 1995. Diagnostics for plant agrochemicals--a meeting of chemistry and immunoassay. In: New Diagnostics in Crop Sciences. CAB International, Oxon, United Kingdom. pp.243-276.
  • Gee SJ, Lucas AD, Hammock BD. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Proceedings of the NATO (North Atlantic Treaty Organisation) Workshop on Methods of Pesticide Exposure Assessment. Ottawa, Canada.
  • Gee SJ, Lucas AD, Hammock BD. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Methods of Pesticide Exposure Assessment. Plenum Press, NY. pp.143-155.
  • Goodrow MH, Sanborn JR, Stoutamire DW, Gee SJ, Hammock BD. 1995. Strategies for immunoassay hapten design. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.119-139.
  • Hammock BD, Gee SJ. 1995. Impact of emerging technologies on immunochemical methods for environmental analysis. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.1-19.
  • Harris AS, Lucas AD, Kramer PM, Marco M, Gee SJ, Hammock BD. 1995. Use of immunoassay for the detection of urinary biomarkers of exposure. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.217-235.
  • Jones G, Wortberg M, Kreissig SB, Hammock BD, Rocke DM. 1995. Sources of experimental variation in calibration curves for enzyme-linked immunosorbent assay. Anal Chim Acta313:197-207.
  • Kreissig SB, Ward VK, Hammock BD, Choudary P. 1995. Nucleotide sequence of the variable region of the heavy and light chains of a monoclonal lgG antibody reactive to herbicides, terbutryn and prometryn. DNA Sequence6:51-54.
  • Kreissig SB, Ward VK, Hammock BD, Choudary P. 1995. Sequence analysis of individual chains of antibodies to triazine herbicides. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.31-49.
  • Lucas AD, Gee SJ, Hammock BD, Seiber JN. 1995. Integration of immunochemical methods with other analytical techniques for pesticide residue determination. J AOAC Int78(3):585-591.
  • Lucas AD, Goodrow MH, Seiber JN, Hammock BD. 1995. Development of an ELISA for the N-dealkylated s-triazines: Application to environmental and biological samples. Food & Agricultural Immunology7:227-241.
  • Marco M, Chiron S, Gascon J, Hammock BD, Barcelo D. 1995. Validation of two immunoassay methods for environmental monitoring of carbaryl and 1-naphthol in ground water samples. Anal Chim Acta311(3):319-329.
  • Schneider P, Gee SJ, Kreissig SB, Harris AS, Kramer PM, Marco M, Lucas AD, Hammock BD. 1995. Troubleshooting during the development and use of immunoassays for environmental monitoring. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.103-122.
  • Sundaram KM, Sundaram A, Gee SJ, Harrison RO, Hammock BD. 1995. Enzyme-linked immunosorb and assay for quantification of Bacillus thuringiensis var. kurstaki crystaline protein in commerical formulations, in relation to total protein content and insecticidal activity. In: Pesticide Formulations and Applicaiton Systems, 14th Volume. American Society for Testing and Materials, Philadelphia, PA.
  • Szekacs A, Hammock BD. 1995. Development of an enzyme-linked immunosorbent assay for the detection of the triazole fungicide myclobutanil. J Agric Food Chem43(8):2083-2091.
  • Szekacs A, Jung F, Hammock BD. 1995. Chemical modification of haptens: Selective amino group protection by chromophores for an immunoassay for aminotriazoles. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.65-75.
  • Szurdoki F, Bekheit HK, Marco M, Goodrow MH, Hammock BD. 1995. Important factors in hapten design and enzyme-linked immunosorbent assay development. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.39-63.
  • Szurdoki F, Kido H, Hammock BD. 1995. Development of assay for analysis of Hg2+ based on sulfur-containing ligands. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.248-264.
  • Szurdoki F, Kido H, Hammock BD. 1995. Development of rapid mercury assays. Synthesis of sulfur-and mercury-containing conjugates. Bioconjug Chem6(2):145-149.
  • Ward VK, Hammock BD, Maeda S, Choudary P. 1995. Development and application of recombinant antibodies to pesticide residue analysis. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.197-216.
  • Ward VK, Kreissig SB, Hammock BD, Choudary P. 1995. Generation of an expression library in the baculovirus expression vector system. J Virol Methods53(2-3):263-272.
  • Wengatz I, Szurdoki F, Swamy AR, Evans L, Patonay G, Stimman E, Delwiche M, Stoutamire DW, Gee SJ, Hammock BD. 1995. Immunoassays for pesticide monitoring. SPIE Proceedings, San Jose, CA 408-416.
  • Wortberg M, Kreissig SB, Jones G, Rocke DM, Hammock BD. 1995. An immunoarray for the simultaneous determination of multiple triazine herbicides. Anal Chim Acta304:339-352.

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