Superfund Research Program
Diagnostic Microarray Apparatus
Patent Status: Issued
Authors: Hammock, B.D., H. Kido, A. Maquieira
A compact assay system having a solid support has at least one capture binding agent on the support surface. By applying a combination of different binding agents on the support surface, the present invention can conduct multiple chemical reactions on the support solid support to detect analytes of interest. The specific reagents, or capture binding agents, are preferably immobilized on the solid support by means of a computer controlled, miniaturized printing system. Specifically, the reagents can be applied onto the solid support using a commercial available printhead of an ink-jet printer. In addition, the support surface also includes areas adapted to be digitally readable by laser to store information concerning binding between capture agents and analytes. The assay system is useful as a sample array holder for performing a variety of chemical analyses, such as matrix assisted laser desorption ionization mass spectrometry analyses.
- University of California-Davis: Immunoassays for Human and Environmental Health Monitoring