Superfund Research Program
Epoxide Hydrolase Inhibitor Methods
Patent Status: Issued
Authors: Hammock, B.D., M.F. Moghaddam, J.M. Cheek, B. Borhan, J. Fergusson, D.F. Grant, J.F. Greene, K. Matoba, J. Zheng, M.F. Sisemore
The present invention provides methods of treating inflammatory diseases mediated by poly-unsaturated lipid metabolites by inhibiting epoxide hydrolase, methods for assaying or screening the epoxide hydrolase inhibitors for inhibitory specificity and for toxicity, and novel biologically active tetrahydrofuran diols of arachidonic acid, including antibodies thereto.
- University of California-Davis: Immunoassays for Human and Environmental Health Monitoring