Skip Navigation

Your Environment. Your Health.

Person Details

Superfund Research Program

Bruce D. Hammock

University of California-Davis
Department of Entomology
90 Briggs Hall
One Shields Avenue
Davis, CA 95616
Phone: 530-752-7519
Fax: 530-752-1537
Email: bdhammock@ucdavis.edu

Projects

Research Briefs

Patents

Hazardous Waste Sites

Frontier Fertilizer

  • University of California-Davis: Immunoassays for Human and Environmental Monitoring

Sulphur Bank Mercury Mine

  • University of California-Davis: Immunoassays for Human and Environmental Monitoring

Publications

2017

  • Wagner SD, Kurobe T, Hammock BG, Lam CH, Wu G, Vasylieva N, Gee SJ, Hammock BD, Teh SJ. 2017. Developmental effects of fipronil on Japanese Medaka (Oryzias latipes) embryos. Chemosphere 166:511-520. doi:10.1016/j.chemosphere.2016.09.069 PMID:27710886

2016

  • Ahn K, Ranganathan A, Bever C, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. 2016. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environ Sci Technol 50(7):3754-3761. doi:10.1021/acs.est.5b05357 PMID:26937944 PMCID:PMC4821808
  • Akintoye E, Wu JH, Hou T, Song X, Yang J, Hammock BD, Mozaffarian D. 2016. Effect of fish oil on monoepoxides derived from fatty acids during cardiac surgery. J Lipid Res 57(3):492-498. doi:10.1194/jlr.P062398 PMID:26749073 PMCID:PMC4766998
  • Bever C, Dong J, Vasylieva N, Barnych B, Cui Y, Hammock BD, Gee SJ. 2016. VHH antibodies: emerging reagents for the analysis of environmental chemicals. Anal Bioanal Chem 408(22):5985-6002. doi:10.1007/s00216-016-9585-x PMID:27209591 PMCID:PMC4983233
  • Ghosh R, Goswami SK, Feitoza LB, Hammock BD, Gomes AV. 2016. Diclofenac induces proteasome and mitochondrial dysfunction in murine cardiomyocytes and hearts. Int J Cardiol 223:923-935. doi:10.1016/j.ijcard.2016.08.233 PMID:27589040 PMCID:PMC5076377
  • Gong Y, Fu Z, Edin ML, Liu C, Wang Z, Shao Z, Fredrick TW, Saba NJ, Morss PC, Burnim SB, Meng SS, Lih FB, Lee KS, Moran EP, SanGiovanni JP, Hellstrom A, Hammock BD, Zeldin DC, Smith LE. 2016. Cytochrome P450 Oxidase 2C Inhibition Adds to ω-3 Long-Chain Polyunsaturated Fatty Acids Protection Against Retinal and Choroidal Neovascularization. Arterioscler Thromb Vasc Biol 36(9):1919-1927. doi:10.1161/ATVBAHA.116.307558 PMID:27417579 PMCID:PMC5010176
  • Goswami SK, Wan D, Yang J, Trindade da Silva CA, Morisseau C, Kodani SD, Yang G, Inceoglu B, Hammock BD. 2016. Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers. J Pharmacol Exp Ther 357(3):529-536. doi:10.1124/jpet.116.232108 PMID:26989141 PMCID:PMC4885505
  • Harris TR, Kodani SD, Yang J, Imai DM, Hammock BD. 2016. An ω-3-enriched diet alone does not attenuate CCl4-induced hepatic fibrosis. J Nutr Biochem 38:93-101. doi:10.1016/j.jnutbio.2016.08.010 PMID:27732914 PMCID:PMC5102762
  • Kim J, Ulu A, Wan DB, Yang J, Hammock BD, Weiss RH. 2016. Addition of DHA Synergistically Enhances the Efficacy of Regorafenib for Kidney Cancer Therapy. Mol Cancer Ther 15(5):890-898. doi:10.1158/1535-7163.MCT-15-0847 PMID:26921392 PMCID:PMC4873345
  • Kitamura S, Hvorecny KL, Niu J, Hammock BD, Madden DR, Morisseau C. 2016. Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa. J Med Chem 59(10):4790-4799. doi:10.1021/acs.jmedchem.6b00173 PMID:27120257 PMCID:PMC4957648
  • Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD. 2016. Parabens inhibit fatty acid amide hydrolase: A potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicol Lett 262:92-99. doi:10.1016/j.toxlet.2016.09.011 PMID:27659731 PMCID:PMC5096949
  • Li D, Liu Y, Zhang X, Lv H, Pang W, Sun X, Gan L, Hammock BD, Ai D, Zhu Y. 2016. Inhibition of soluble epoxide hydrolase alleviated atherosclerosis by reducing monocyte infiltration in Ldlr(-/-) mice. J Mol Cell Cardiol 98:128-137. doi:10.1016/j.yjmcc.2016.08.001 PMID:27496380
  • Mouchlis VD, Morisseau C, Hammock BD, Li S, McCammon JA, Dennis EA. 2016. Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and selective inhibitors of Group VIA calcium-independent phospholipase A2. Bioorg Med Chem 24(20):4801-4811. doi:10.1016/j.bmc.2016.05.009 PMID:27320659 PMCID:PMC5053890
  • Ren Q, Ma M, Ishima T, Morisseau C, Yang J, Wagner KM, Zhang J, Yao W, Dong C, Han M, Hammock BD, Hashimoto K. 2016. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proc Natl Acad Sci U S A 113(13):E1944-E1952. doi:10.1073/pnas.1601532113 PMID:26976569 PMCID:PMC4822604
  • Sharma A, Hye Khan A, Levick SP, Sing K, Hammock BD, Imig JD. 2016. Novel Omega-3 Fatty Acid Epoxygenase Metabolite Reduces Kidney Fibrosis. Int J Mol Sci 17(5):doi:10.3390/ijms17050751 PMID:27213332 PMCID:PMC4881572
  • Shih P, Yang J, Morisseau C, German JB, Zeeland AA, Armando AM, Quehenberger O, Bergen AW, Magistretti P, Berrettini W, Halmi KA, Schork N, Hammock BD, Kaye W. 2016. Dysregulation of soluble epoxide hydrolase and lipidomic profiles in anorexia nervosa. Mol Psychiatry 21(4):537-546. doi:10.1038/mp.2015.26 PMID:25824304 PMCID:PMC4591075
  • Sirish P, Li N, Timofeyev V, Zhang X, Wang L, Yang J, Lee KS, Bettaieb A, Ma S, Lee JH, Su D, Lau V, Myers R, Lieu DK, Lopez JE, Young JN, Yamoah EN, Haj FG, Ripplinger C, Hammock BD, Chiamvimonvat N. 2016. Molecular Mechanisms and New Treatment Paradigm for Atrial Fibrillation. Circ Arrhythm Electrophysiol 9(5):doi:10.1161/CIRCEP.115.003721 PMID:27162031 PMCID:PMC4869994
  • Taha AY, Hennebelle M, Yang J, Zamora D, Rapoport SI, Hammock BD, Ramsden CE. 2016. Regulation of rat plasma and cerebral cortex oxylipin concentrations with increasing levels of dietary linoleic acid. Prostaglandins Leukot Essent Fatty Acids doi:10.1016/j.plefa.2016.05.004 PMID:27282298 PMCID:PMC5106341
  • Tong X, Khandelwal AR, Wu X, Xu Z, Yu W, Chen C, Zhao W, Yang J, Qin Z, Weisbrod RM, Seta F, Ago T, Sing K, Lee S, Hammock BD, Sadoshima J, Cohen RA, Zeng C. 2016. Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase. J Mol Cell Cardiol 92:30-40. doi:10.1016/j.yjmcc.2016.01.020 PMID:26812119 PMCID:PMC5008453
  • Wagner KM, Lee KS, Yang J, Hammock BD. 2016. Epoxy fatty acids mediate analgesia in murine diabetic neuropathy. Eur J Pain doi:10.1002/ejp.939 PMID:27634339
  • Wu X, Yang J, Morisseau C, Robertson LW, Hammock BD, Lehmler H. 2016. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats. J Toxicol Sci 152(2):309-322. doi:10.1093/toxsci/kfw084 PMID:27208083 PMCID:PMC4960907
  • Xu J, Morisseau C, Yang J, Lee KS, Kamita SG, Hammock BD. 2016. Ingestion of the epoxide hydrolase inhibitor AUDA modulates immune responses of the mosquito, Culex quinquefasciatus during blood feeding. Insect Biochem Mol Biol 76:62-69. doi:10.1016/j.ibmb.2016.06.011 PMID:27369469 PMCID:PMC5010450

2015

  • Bahl CD, Hvorecny KL, Bomberger JM, Stanton BA, Hammock BD, Morisseau C, Madden DR. 2015. Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR. Angew Chem Int Ed Engl 54(34):9881-9885. doi:10.1002/anie.201503983 PMID:26136396 PMCID:PMC4556431
  • Berthelot CC, Kamita SG, Sacchi R, Yang J, Nording ML, Georgi K, Karbowski CH, German JB, Weiss RH, Hogg RJ, Hammock BD, Zivkovic AM. 2015. Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation. PLoS One 10(12):e0144996. doi:10.1371/journal.pone.0144996 PMID:26672987 PMCID:PMC4681469
  • Bettaieb A, Chahed S, Bachaalany S, Griffey S, Hammock BD, Haj FG. 2015. Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice. Mol Pharmacol 88(2):281-290. doi:10.1124/mol.114.097501 PMID:25993999 PMCID:PMC4518092
  • Burmistrov V, Morisseau C, Danilov D, Harris TR, Dalinger I, Vatsadze I, Shkineva T, Butov GM, Hammock BD. 2015. 1,3-Disubstituted and 1,3,3-trisubstituted adamantyl-ureas with isoxazole as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett 25(23):5514-5519. doi:10.1016/j.bmcl.2015.10.066 PMID:26520661 PMCID:PMC4654407
  • Cui Y, Li D, Morisseau C, Dong J, Yang J, Wan D, Rossotti MA, Gee SJ, Gonzalez-Sapienza GG, Hammock BD. 2015. Heavy chain single-domain antibodies to detect native human soluble epoxide hydrolase. Anal Bioanal Chem 407(24):7275-7283. doi:10.1007/s00216-015-8889-6 PMID:26229025 PMCID:PMC4573264
  • Fahrmann J, Grapov D, Yang J, Hammock BD, Fiehn O, Bell GI, Hara M. 2015. Systemic alterations in the metabolome of diabetic NOD mice delineate increased oxidative stress accompanied by reduced inflammation and hypertriglyceremia. Am J Physiol Endocrinol Metab 308(11):E978-E989. doi:10.1152/ajpendo.00019.2015 PMID:25852003 PMCID:PMC4451288
  • Flannery BM, Silverman JL, Bruun DA, Puhger KR, McCoy MR, Hammock BD, Crawley JN, Lein PJ. 2015. Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine. Neurotoxicol Teratol 47:36-45. doi:10.1016/j.ntt.2014.10.008 PMID:25446016 PMCID:PMC4291292
  • Goswami SK, Inceoglu B, Yang J, Wan D, Kodani SD, Trindade da Silva CA, Morisseau C, Hammock BD. 2015. Omeprazole increases the efficacy of a soluble epoxide hydrolase inhibitor in a PGE₂ induced pain model. Toxicol Appl Pharmacol 289(3):419-427. doi:10.1016/j.taap.2015.10.018 PMID:26522832 PMCID:PMC4666679
  • Hammock BD, Hobbs JA, Slater SB, Acuna S, Teh SJ. 2015. Contaminant and food limitation stress in an endangered estuarine fish. Sci Total Environ 532:316-326. doi:10.1016/j.scitotenv.2015.06.018 PMID:26081734 PMCID:PMC4843802
  • Harris TR, Bettaieb A, Kodani SD, Dong H, Myers R, Chiamvimonvat N, Haj FG, Hammock BD. 2015. Inhibition of soluble epoxide hydrolase attenuates hepatic fibrosis and endoplasmic reticulum stress induced by carbon tetrachloride in mice. Toxicol Appl Pharmacol 286(2):102-111. doi:10.1016/j.taap.2015.03.022 PMID:25827057 PMCID:PMC4458210
  • Hua X, Zhou L, Feng L, Ding Y, Shi H, Wang L, Gee SJ, Hammock BD, Wang M. 2015. Competitive and noncompetitive phage immunoassays for the determination of benzothiostrobin. Anal Chim Acta 890:150-156. doi:10.1016/j.aca.2015.07.056 PMID:26347177 PMCID:PMC4791039
  • Hwang VJ, Kim J, Rand A, Yang C, Sturdivant S, Hammock BD, Bell P, Guay-Woodford LM, Weiss RH. 2015. The cpk model of recessive PKD shows glutamine dependence associated with the production of the oncometabolite 2-hydroxyglutarate. Am J Physiol Renal Physiol 309(6):F492-F498. doi:10.1152/ajprenal.00238.2015 PMID:26155843 PMCID:PMC4572393
  • Inceoglu B, Bettaieb A, Trindade da Silva CA, Lee KS, Haj FG, Hammock BD. 2015. Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain. Proc Natl Acad Sci U S A 112(29):9082-9087. doi:10.1073/pnas.1510137112 PMID:26150506 PMCID:PMC4517273
  • Kim J, Yoon SP, Toews ML, Imig JD, Hwang SH, Hammock BD, Padanilam BJ. 2015. Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy. Am J Physiol Renal Physiol 308(2):F131-F139. doi:10.1152/ajprenal.00531.2014 PMID:25377915 PMCID:PMC4338924
  • Kitamura S, Morisseau C, Inceoglu B, Kamita SG, De Nicola GR, Nyegue M, Hammock BD. 2015. Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo. PLoS One 10(2):e0117438. doi:10.1371/journal.pone.0117438 PMID:25659109 PMCID:PMC4319826
  • Liu X, Xu Y, Wan D, Xiong Y, He Z, Wang X, Gee SJ, Ryu D, Hammock BD. 2015. Development of a nanobody-alkaline phosphatase fusion protein and its application in a highly sensitive direct competitive fluorescence enzyme immunoassay for detection of ochratoxin A in cereal. Anal Chem 87(2):1387-1394. doi:10.1021/ac504305z PMID:25531426 PMCID:PMC4476795
  • Lopez-Vicario C, Alcaraz-Quiles J, Garcia-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BD, Arroyo V, Claria J. 2015. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides. Proc Natl Acad Sci U S A 112(2):536-541. doi:10.1073/pnas.1422590112 PMID:25550510 PMCID:PMC4299190
  • Nording M, Yang J, Hoang L, Zamora V, Uyeminami DL, Espiritu I, Pinkerton KE, Hammock BD, Luria A. 2015. Bioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposure. Metabolomics 1:doi:10.7243/2059-0008-1-1 PMID:27076918 PMCID:PMC4827720
  • Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb N. 2015. Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea (TPPU): Resulting drug levels and modulation of oxylipin pattern. Prostaglandins Other Lipid Mediat 121(PtA):131-137. doi:10.1016/j.prostaglandins.2015.06.005 PMID:26117215 PMCID:PMC4688279
  • Ranganathan A, Gee SJ, Hammock BD. 2015. An immunoassay for the detection of triclosan-O-glucuronide, a primary human urinary metabolite of triclosan. Anal Bioanal Chem 407(24):7263-7273. doi:10.1007/s00216-015-8918-5 PMID:26255293 PMCID:PMC4580343
  • Rossotti MA, Pirez M, Gonzalez-Techera A, Cui Y, Bever C, Lee KS, Morisseau C, Leizagoyen C, Gee SJ, Hammock BD, Gonzalez-Sapienza GG. 2015. Method for Sorting and Pairwise Selection of Nanobodies for the Development of Highly Sensitive Sandwich Immunoassays. Anal Chem 87(23):11907-11914. doi:10.1021/acs.analchem.5b03561 PMID:26544909 PMCID:PMC4666776
  • Samokhvalov V, Zlobine I, Jamieson KL, Jurasz P, Chen C, Lee KS, Hammock BD, Seubert JM. 2015. PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells. Toxicol Lett 232(1):10-20. doi:10.1016/j.toxlet.2014.09.029 PMID:25300478 PMCID:PMC4486642
  • Sasso O, Wagner KM, Morisseau C, Inceoglu B, Hammock BD, Piomelli D. 2015. Peripheral FAAH and soluble epoxide hydrolase inhibitors are synergistically antinociceptive. Pharmacol Res 97:7-15. doi:10.1016/j.phrs.2015.04.001 PMID:25882247 PMCID:PMC4464910
  • Shihadih DS, Harris TR, Yang J, Merzlikin O, Lee KS, Hammock BD, Morisseau C. 2015. Identification of potent inhibitors of the chicken soluble epoxide hydrolase. Bioorg Med Chem Lett 25(2):276-279. doi:10.1016/j.bmcl.2014.11.053 PMID:25479771 PMCID:PMC4277729
  • Vasylieva N, Ahn K, Barnych B, Gee SJ, Hammock BD. 2015. Development of an Immunoassay for the Detection of the Phenylpyrazole Insecticide Fipronil. Environ Sci Technol 49(16):10038-10047. doi:10.1021/acs.est.5b01005 PMID:26196357 PMCID:PMC4605820
  • Walkowska A, Kuczeriszka M, Sadowski J, Olszyñski KH, Dobrowolski L, Červenka L, Hammock BD, Kompanowska-Jezierska E. 2015. High salt intake increases blood pressure in normal rats: putative role of 20-HETE and no evidence on changes in renal vascular reactivity. Kidney Blood Press Res 40(3):323-334. doi:10.1159/000368508 PMID:26067851 PMCID:PMC4583220
  • Wang J, Majkova Z, Bever C, Yang J, Gee SJ, Li J, Xu T, Hammock BD. 2015. One-step immunoassay for tetrabromobisphenol a using a camelid single domain antibody-alkaline phosphatase fusion protein. Anal Chem 87(9):4741-4748. doi:10.1021/ac504735p PMID:25849972 PMCID:PMC4476793
  • Wecksler AT, Hwang SH, Liu J, Wettersten HI, Morisseau C, Wu J, Weiss RH, Hammock BD. 2015. Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemother Pharmacol 75(1):161-171. doi:10.1007/s00280-014-2626-2 PMID:25413440 PMCID:PMC4400119
  • Xu J, Morisseau C, Yang J, Mamatha DM, Hammock BD. 2015. Epoxide hydrolase activities and epoxy fatty acids in the mosquito Culex quinquefasciatus. Insect Biochem Mol Biol 59:41-49. doi:10.1016/j.ibmb.2015.02.004 PMID:25686802 PMCID:PMC4387068
  • Yang J, Bratt J, Franzi L, Liu J, Zhang G, Zeki AA, Vogel CF, Williams K, Dong H, Lin Y, Hwang SH, Kenyon NJ, Hammock BD. 2015. Soluble epoxide hydrolase inhibitor attenuates inflammation and airway hyperresponsiveness in mice. Am J Respir Cell Mol Biol 52(1):46-55. doi:10.1165/rcmb.2013-0440OC PMID:24922186 PMCID:PMC4370250

2014

  • Bettaieb A, Chahed S, Tabet G, Yang J, Morisseau C, Griffey S, Hammock BD, Haj FG. 2014. Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice. PLoS One 9(11):e113019. doi:10.1371/journal.pone.0113019 PMID:25402489 PMCID:PMC4234494
  • Bever C, Majkova Z, Radhakrishnan R, Suni II, McCoy MR, Wang Y, Dechant JE, Gee SJ, Hammock BD. 2014. Development and utilization of camelid VHH antibodies from alpaca for 2,2',4,4'-tetrabrominated diphenyl ether detection. Anal Chem 86(15):7875-7882. doi:10.1021/ac501807j PMID:25005746 PMCID:PMC4144723
  • Burmistrov V, Morisseau C, Lee KS, Shihadih DS, Harris TR, Butov GM, Hammock BD. 2014. Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett 24(9):2193-2197. doi:10.1016/j.bmcl.2014.03.016 PMID:24685540 PMCID:PMC4019751
  • Charles RL, Rudyk O, Prysyazhna O, Kamynina A, Yang J, Morisseau C, Hammock BD, Freeman BA, Eaton P. 2014. Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase. Proc Natl Acad Sci U S A 111(22):8167-8172. doi:10.1073/pnas.1402965111 PMID:24843165 PMCID:PMC4050620
  • Chen A, Wang R, Bever C, Xing S, Hammock BD, Pan T. 2014. Smartphone-interfaced lab-on-a-chip devices for field-deployable enzyme-linked immunosorbent assay. Biomicrofluidics 8(6):064101. doi:10.1063/1.4901348 PMID:25553178 PMCID:PMC4241779
  • Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F. 2014. Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. J Am Heart Assoc 3(4):doi:10.1161/JAHA.114.001015 PMID:25146704 PMCID:PMC4310392
  • Dong J, Xu C, Wang H, Xiao Z, Gee SJ, Li Z, Wang F, Wu W, Shen Y, Yang J, Sun Y, Hammock BD. 2014. Enhanced sensitive immunoassay: noncompetitive phage anti-immune complex assay for the determination of malachite green and leucomalachite green. J Agric Food Chem 62(34):8752-8758. doi:10.1021/jf5019824 PMID:25077381 PMCID:PMC4150606
  • Hua X, Yin W, Shi H, Li M, Wang Y, Wang H, Ye Y, Kim H, Gee SJ, Wang M, Liu F, Hammock BD. 2014. Development of phage immuno-loop-mediated isothermal amplification assays for organophosphorus pesticides in agro-products. Anal Chem 86(16):8441-8447. doi:10.1021/ac5020657 PMID:25135320 PMCID:PMC4139188
  • Kim J, Imig JD, Yang J, Hammock BD, Padanilam BJ. 2014. Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation. Am J Physiol Renal Physiol 307(8):F971-F980. doi:10.1152/ajprenal.00256.2014 PMID:25164080 PMCID:PMC4200297
  • Kujal P, Chabova VC, Skaroupkova P, Huskova Z, Vernerova Z, Kramer HJ, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Cervenka L. 2014. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clin Exp Pharmacol Physiol 41(3):227-237. doi:10.1111/1440-1681.12204 PMID:24471737 PMCID:PMC4038339
  • Lee KS, Liu J, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, Wulff H, Newcomer ME, Zeldin DC, Hammock BD. 2014. Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J Med Chem 57(16):7016-7030. doi:10.1021/jm500694p PMID:25079952 PMCID:PMC4148150
  • Liu X, Xu Y, Xiong Y, Tu Z, Li Y, He Z, Qiu Y, Fu J, Gee SJ, Hammock BD. 2014. VHH phage-based competitive real-time immuno-polymerase chain reaction for ultrasensitive detection of ochratoxin A in cereal. Anal Chem 86(15):7471-7477. doi:10.1021/ac501202d PMID:24992514 PMCID:PMC4306448
  • Morisseau C, Wecksler AT, Deng C, Dong H, Yang J, Lee KS, Kodani SD, Hammock BD. 2014. Effect of soluble epoxide hydrolase polymorphism on substrate and inhibitor selectivity and dimer formation. J Lipid Res 55(6):1131-1138. doi:10.1194/jlr.M049718 PMID:24771868 PMCID:PMC4031944
  • Ono E, Dutile S, Kazani S, Weschsler ME, Yang J, Hammock BD, Douda DN, Tabet Y, Khaddaj-Mallat R, Sirois M, Sirois C, Rizcallah E, Rousseau E, Martin R, Sutherland E, Castro M, Jarjour NN, Israel E, Levy BD. 2014. Lipoxin generation is related to soluble epoxide hydrolase activity in severe asthma. Am J Respir Crit Care Med 190(8):886-897. doi:10.1164/rccm.201403-0544OC PMID:25162465 PMCID:PMC4299578
  • Radhakrishnan R, Suni II, Bever C, Hammock BD. 2014. Impedance Biosensors: Applications to Sustainability and Remaining Technical Challenges. ACS Sustain Chem Eng 2(7):1649-1655. doi:10.1021/sc500106y PMID:25068095 PMCID:PMC4105195
  • Schebb N, Muvvala JB, Morin D, Buckpitt AR, Hammock BD, Rice RH. 2014. Metabolic activation of the antibacterial agent triclocarban by cytochrome P450 1A1 yielding glutathione adducts. Drug Metab Dispos 42(7):1098-1102. doi:10.1124/dmd.114.058206 PMID:24733789 PMCID:PMC4170114
  • Schebb N, Ostermann AI, Yang J, Hammock BD, Hahn A, Schuchardt J. 2014. Comparison of the effects of long-chain omega-3 fatty acid supplementation on plasma levels of free and esterified oxylipins. Prostaglandins Other Lipid Mediat 113-115:21-29. doi:10.1016/j.prostaglandins.2014.05.002 PMID:24880049 PMCID:PMC4247815
  • Schuchardt J, Schmidt S, Kressel G, Willenberg I, Hammock BD, Hahn A, Schebb N. 2014. Modulation of blood oxylipin levels by long-chain omega-3 fatty acid supplementation in hyper- and normolipidemic men. Prostaglandins Leukot Essent Fatty Acids 90:27-37. doi:10.1016/j.plefa.2013.12.008 PMID:24411718 PMCID:PMC4130704
  • Schuchardt J, Schneider I, Willenberg I, Yang J, Hammock BD, Hahn A, Schebb N. 2014. Increase of EPA-derived hydroxy, epoxy and dihydroxy fatty acid levels in human plasma after a single dose of long-chain omega-3 PUFA. Prostaglandins Other Lipid Mediat 109-111:23-31. doi:10.1016/j.prostaglandins.2014.03.001 PMID:24667634 PMCID:PMC4172375
  • Sporkova A, Jichova S, Huskova Z, Kopkan L, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L. 2014. Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats. Clin Exp Pharmacol Physiol 41(12):1003-1013. doi:10.1111/1440-1681.12310 PMID:25224811 PMCID:PMC4347520
  • Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn K, Gee SJ, Hammock BD. 2014. Determination of the pyrethroid insecticide metabolite 3-PBA in plasma and urine samples from farmer and consumer groups in northern Thailand. J Environ Sci Health B 49(1):15-22. doi:10.1080/03601234.2013.836862 PMID:24138464 PMCID:PMC4020914
  • Trunnelle KJ, Bennett DH, Ahn K, Schenker MB, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hammock BD. 2014. Concentrations of the urinary pyrethroid metabolite 3-phenoxybenzoic acid in farm worker families in the MICASA study. Environ Res 131:153-159. doi:10.1016/j.envres.2014.03.003 PMID:24721133 PMCID:PMC4152318
  • Ulu A, Lee S, Miyabe C, Yang J, Hammock BG, Dong H, Hammock BD. 2014. An omega-3 epoxide of docosahexaenoic acid lowers blood pressure in angiotensin-II-dependent hypertension. J Cardiovasc Pharmacol 64(1):87-99. doi:10.1097/FJC.0000000000000094 PMID:24691274 PMCID:PMC4092041
  • Wagner KM, Vito S, Inceoglu B, Hammock BD. 2014. The role of long chain fatty acids and their epoxide metabolites in nociceptive signaling. Prostaglandins Other Lipid Mediat 113-115:2-12. doi:10.1016/j.prostaglandins.2014.09.001 PMID:25240260 PMCID:PMC4254344
  • Wagner KM, Yang J, Inceoglu B, Hammock BD. 2014. Soluble epoxide hydrolase inhibition is antinociceptive in a mouse model of diabetic neuropathy. J Pain 15(9):907-914. doi:10.1016/j.jpain.2014.05.008 PMID:24924124 PMCID:PMC4150748
  • Wang J, Bever C, Majkova Z, Dechant JE, Yang J, Gee SJ, Xu T, Hammock BD. 2014. Heterologous antigen selection of camelid heavy chain single domain antibodies against tetrabromobisphenol A. Anal Chem 86(16):8296-8302. doi:10.1021/ac5017437 PMID:25068372 PMCID:PMC4139172
  • Wang W, Zhu J, Lyu F, Panigrahy D, Ferrara KW, Hammock BD, Zhang G. 2014. ω-3 polyunsaturated fatty acids-derived lipid metabolites on angiogenesis, inflammation and cancer. Prostaglandins Other Lipid Mediat 113-115:13-20. doi:10.1016/j.prostaglandins.2014.07.002 PMID:25019221 PMCID:PMC4306447
  • Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD. 2014. Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anticancer Drugs 25(4):433-446. doi:10.1097/CAD.0000000000000079 PMID:24525589 PMCID:PMC3947856
  • Xu J, Morisseau C, Hammock BD. 2014. Expression and characterization of an epoxide hydrolase from Anopheles gambiae with high activity on epoxy fatty acids. Insect Biochem Mol Biol 54:42-52. doi:10.1016/j.ibmb.2014.08.004 PMID:25173592 PMCID:PMC4252830
  • Yueh MF, Taniguchi K, Chen S, Evans RM, Hammock BD, Karin M, Tukey RH. 2014. The commonly used antimicrobial additive triclosan is a liver tumor promoter. Proc Natl Acad Sci U S A 111(48):17200-17205. doi:10.1073/pnas.1419119111 PMID:25404284 PMCID:PMC4260592
  • Zhang G, Kodani SD, Hammock BD. 2014. Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer. Prog Lipid Res 53:108-123. doi:10.1016/j.plipres.2013.11.003 PMID:24345640 PMCID:PMC3914417
  • Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu J, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. 2014. Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. Proc Natl Acad Sci U S A 111(30):11127-11132. doi:10.1073/pnas.1410432111 PMID:25024195 PMCID:PMC4121808

2013

  • Bettaieb A, Nagata N, AbouBechara D, Chahed S, Morisseau C, Hammock BD, Haj FG. 2013. Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue. J Biol Chem 288:14189-14199. doi:10.1074/jbc.M113.458414 PMID:23576437 PMCID:PMC3656275
  • Chen T, Takrouri K, Hee-Hwang S, Rana S, Yefidoff-Freedman R, Halperin J, Natarajan A, Morisseau C, Hammock BD, Chorev M, Aktas BH. 2013. Explorations of substituted urea functionality for the discovery of new activators of the heme-regulated inhibitor kinase. J Med Chem 56(23):9457-9470. doi:10.1021/jm400793v PMID:24261904 PMCID:PMC3938169
  • Falck D, Schebb N, Prihatiningtyas S, Zhang J, Heus F, Morisseau C, Kool J, Hammock BD, Niessen WM. 2013. Development of on-line liquid chromatography-biochemical detection for soluble epoxide hydrolase inhibitors in mixtures. Chromatographia 76:13-21. doi:10.1007/s10337-012-2343-0 PMID:23526703 PMCID:PMC3601784
  • Frolov A, Dong H, Jiang M, Yang L, Cook EC, Matnani R, Hammock BD, Crofford LJ. 2013. Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis. J Biol Chem 288:23696-23703. doi:10.1074/jbc.M112.445916 PMID:23814065 PMCID:PMC3745317
  • Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ. 2013. Anti-inflammatory properties of prostaglandin E2: Deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice. Prostaglandins Leukot Essent Fatty Acids 89(5):351-358. doi:10.1016/j.plefa.2013.08.003 PMID:24055573 PMCID:PMC3897272
  • Gardell AM, Yang J, Sacchi R, Fangue NA, Hammock BD, Kültz D. 2013. Tilapia (Oreochromis mossambicus) brain cells respond to hyperosmotic challenge by inducing myo-inositol biosynthesis. Journal of Experimental Biology 216(24):4615-4625. doi:10.1242/jeb.088906 PMID:24072790 PMCID:PMC3851147
  • Guedes AP, Morisseau C, Sole A, Soares JN, Ulu A, Dong H, Hammock BD. 2013. Use of a soluble epoxide hydrolase inhibitor as an adjunctive analgesic in a horse with laminitis. Vet Anaesth Analg 40(4):440-448. doi:10.1111/vaa.12030 PMID:23463912 PMCID:PMC3956586
  • Han J, Kim H, Sudheendra L, Gee SJ, Hammock BD, Kennedy IM. 2013. Photonic crystal lab-on-a-chip for detecting staphylococcal entertoxin B at low attomolar concentration. Anal Chem 85(6):3104-3109. doi:10.1021/ac303016h PMID:23418954 PMCID:PMC3608201
  • Han J, Kim H, Sudheendra L, Hass EA, Gee SJ, Hammock BD, Kennedy IM. 2013. Electrophoretic build-up of multi nanoparticle array for a highly sensitive immunoassay. Biosens Bioelectron 41:302-308. doi:10.1016/j.bios.2012.08.042 PMID:23021853 PMCID:PMC3525773
  • Hwang SH, Wecksler AT, Wagner KM, Hammock BD. 2013. Rationally designed multitarget agents against inflammation and pain. Curr Med Chem 20(13):1783-1799. doi:10.2174/0929867311320130013 PMID:23410172 PMCID:PMC4113248
  • Hwang SH, Wecksler AT, Zhang G, Morisseau C, Nguyen LV, Fu SH, Hammock BD. 2013. Synthesis and biological evaluation of sorafenib- and regorafenib- like sEH inhibitors. Bioorg Med Chem Lett 23(13):3732-3737. doi:10.1016/j.bmcl.2013.05.011 PMID:23726028 PMCID:PMC3744640
  • Inceoglu B, Zolkowska D, Yoo H, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. 2013. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. PLoS One 8(12):doi:10.1371/journal.pone.0080922 PMID:24349022 PMCID:PMC3862847
  • Kamita SG, Oshita GH, Wang P, Morisseau C, Hammock BD, Nandety R, Falk BW. 2013. Characterization of HOVI-MEH1, a microsomal epoxide hydrolase from the Glassy-Winged Sharpshooter Homalodisca vitripennis. Arch Insect Biochem Physiol 83(4):171-179. doi:10.1002/arch.21100 PMID:23704009 PMCID:PMC3846607
  • Kamita SG, Yamamoto K, Dadala MM, Pha K, Morisseau C, Escaich A, Hammock BD. 2013. Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens. Insect Biochem Mol Biol 43(3):219-228. doi:10.1016/j.ibmb.2012.12.002 PMID:23276675 PMCID:PMC3577957
  • Lee KS, Morisseau C, Yang J, Wang P, Hwang SH, Hammock BD. 2013. Forster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase. Anal Biochem 434(2):259-268. doi:10.1016/j.ab.2012.11.015 PMID:23219719 PMCID:PMC3632402
  • Liu J, Lin Y, Qiu H, Morisseau C, Rose TE, Hwang SH, Chiamvimonvat N, Hammock BD. 2013. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. European Journal of Pharmaceutical Sciences 48(4-5):619-627. doi:10.1016/j.ejps.2012.12.013 PMID:23291046 PMCID:PMC3596469
  • Morisseau C, Hammock BD. 2013. Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annu Rev Pharmacol Toxicol 53:37-58. doi:10.1146/annurev-pharmtox-011112-140244 PMID:23020295 PMCID:PMC3578707
  • Morisseau C, Pakhomova S, Hwang SH, Newcomer ME, Hammock BD. 2013. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorg Med Chem Lett 23(13):3818-3821. doi:10.1016/j.bmcl.2013.04.083 PMID:23684894 PMCID:PMC3703951
  • Morisseau C, Sahdeo S, Cortopassi GA, Hammock BD. 2013. Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries. Anal Biochem 434(1):105-111. doi:10.1016/j.ab.2012.11.017 PMID:23219563 PMCID:PMC3557602
  • Nording ML, Yang J, Georgi K, Karbowski CH, German JB, Weiss RH, Hogg RJ, Trygg J, Hammock BD, Zivkovic AM. 2013. Individual variation in lipidomic profiles of healthy subjects in response to omega-3 Fatty acids. PLoS One 8:e76575. doi:10.1371/journal.pone.0076575 PMID:24204640 PMCID:PMC3811983
  • Panigrahy D, Kalish BT, Huang S, Bielenberg DR, Le HD, Yang J, Edin ML, Lee CR, Benny O, Mudge DK, Butterfield CE, Mammoto A, Mammoto T, Inceoglu B, Jenkins RL, Simpson MA, Akino T, Lih FB, Tomer KB, Ingber DE, Hammock BD, Falck JR, Manthati VL, Kaipainen A, D'Amore PA, Puder M, Zeldin DC, Kieran MW. 2013. Epoxyeicosanoids promote organ and tissue regeneration. Proc Natl Acad Sci U S A 110(33):13528-13533. doi:10.1073/pnas.1311565110 PMID:23898174 PMCID:PMC3746918
  • Poli G, Corda E, Martino P, Dall'Ara P, Bareggi SR, Bondiolotti G, Iulini B, Mazza M, Casalone C, Hwang SH, Hammock BD, Inceoglu B. 2013. Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie. Life Sciences 92(23):1145-1150. doi:10.1016/j.lfs.2013.04.014 PMID:23651659 PMCID:PMC3806320
  • Ranganathan A, Paradise GA, Hansen CA, McCoy MR, Gee SJ, Zhong P, Chang D, Hammock BD. 2013. Indirect homologous competitive enzyme-linked immunosorbent assay for the detection of a class of glycosylated dihydrochalcones. J Agric Food Chem 61(28):6964-6970. doi:10.1021/jf401302y PMID:23767873 PMCID:PMC3723731
  • Schuchardt J, Schmidt S, Kressel G, Dong H, Willenberg I, Hammock BD, Hahn A, Schebb N. 2013. Comparison of free serum oxylipin concentrations in hyper- vs. normolipidemic men. Prostaglandins Leukot Essent Fatty Acids 89(1):19-29. doi:10.1016/j.plefa.2013.04.001 PMID:23694766 PMCID:PMC4057063
  • Sirish P, Li N, Liu J, Lee KS, Hwang SH, Qiu H, Zhao C, Ma S, Lopez JE, Hammock BD, Chiamvimonvat N. 2013. Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis. Proc Natl Acad Sci U S A 110(14):5618-5623. doi:10.1073/pnas.1221972110 PMID:23493561 PMCID:PMC3619365
  • Smilowitz JT, Zivkovic AM, Wan YY, Watkins SM, Nording M, Hammock BD, German JB. 2013. Nutritional lipidomics: Molecular metabolism, analytics, and diagnostics. Mol Nutr Food Res 57(8):1319-1335. doi:10.1002/mnfr.201200808 PMID:23818328 PMCID:PMC3806310
  • Stewart DN, Lango J, Nambiar KP, Falso MS, Fitzgerald PG, Rocke DM, Hammock BD, Buchholz BA. 2013. Carbon turnover in the water-soluble protein of the adult human lens. Mol Vis 19:463-475. PMID:23441119 PMCID:PMC3580966
  • Trunnelle KJ, Bennett DH, Tancredi DJ, Gee SJ, Stoecklin-Marois MT, Hennessy-Burt TE, Hammock BD, Schenker MB. 2013. Pyrethroids in house dust from the homes of farm worker families in the MICASA study. Environ Int 61:57-63. doi:10.1016/j.envint.2013.09.007 PMID:24096042 PMCID:PMC4059492
  • Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif A, Liu J, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. 2013. Anti-inflammatory effects of omega-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II dependent hypertension. J Cardiovasc Pharmacol 62(3):285-297. doi:10.1097/FJC.0b013e318298e460 PMID:23676336 PMCID:PMC3773051
  • Van Bogaert I, Zhang G, Yang J, Liu J, Ye Y, Soetaert W, Hammock BD. 2013. Preparation of 20- HETE using multifunctional enzyme type 2-negative Starmerella bombicola. J Lipid Res 54(11):3215-3219. doi:10.1194/jlr.D042226 PMID:23966667 PMCID:PMC3793626
  • Vanrell L, Gonzalez-Techera A, Hammock BD, Gonzalez-Sapienza GG. 2013. Nanopeptamers for the development of small-analyte lateral flow tests with a positive readout. Anal Chem 85(2):1177-1182. doi:10.1021/ac3031114 PMID:23214940 PMCID:PMC3904493
  • Wagner KM, Inceoglu B, Dong H, Yang J, Hwang SH, Jones PD, Morisseau C, Hammock BD. 2013. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. Eur J Pharmacol 700(1-3):93-101. doi:10.1016/j.ejphar.2012.12.015 PMID:23276668 PMCID:PMC3578047
  • Wang Y, Li P, Majkova Z, Bever C, Kim H, Zhang Q, Dechant JE, Gee SJ, Hammock BD. 2013. Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay. Anal Chem 85(17):8298-8303. doi:10.1021/ac4015885 PMID:23965250 PMCID:PMC3787825
  • Wang Y, Wang H, Li P, Zhang Q, Kim H, Gee SJ, Hammock BD. 2013. Correction to: Phage- displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem 61(16):3994-3994. doi:10.1021/jf401235p PMID:23394544 PMCID:PMC3830680
  • Wang Y, Wang H, Li P, Zhang Q, Kim H, Gee SJ, Hammock BD. 2013. Phage-displayed peptide that mimics aflatoxins and its application in immunoassay. J Agric Food Chem 61(10):2426–2433. doi:10.1021/jf4004048 PMID:23394544 PMCID:PMC3830680
  • Wettersten HI, Hwang SH, Li C, Shiu EY, Wecksler AT, Hammock BD, Weiss RH. 2013. A novel p21 attenuator which is structurally related to sorafenib. Cancer Biol Ther 14:278-285. doi:10.4161/cbt.23374 PMID:23298903 PMCID:PMC3595311
  • Yang J, Solaimani P, Dong H, Hammock BD, Hankinson O. 2013. Treatment of mice with 2,3,7,8-Tetrachlorodibenzo-p-dioxin markedly increases the levels of a number of cytochrome P450 metabolites of omega-3 polyunsaturated fatty acids in the liver and lung. J Toxicol Sci 38(6):833-836. PMID:24213002 PMCID:PMC4068614
  • Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu J, Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. 2013. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A 110(16):6530-6535. doi:10.1073/pnas.1304321110 PMID:23553837 PMCID:PMC3631682
  • Zhang W, Li H, Dong H, Liao J, Hammock BD, Yang G. 2013. Soluble epoxide hydrolase deficiency inhibits dextran sulfate sodium-induced colitis and carcinogenesis in mice. Anticancer Res 33(12):5261-5271. PMID:24324059 PMCID:PMC4076172

2012

  • Ahn K, Kasagami T, Tsai H, Schebb N, Ogunyoku TA, Gee SJ, Young TM, Hammock BD. 2012. An Immunoassay to Evaluate Human/Environmental Exposure to the Antimicrobial Triclocarban. Environ Sci Technol 46:374-381. doi:10.1021/es202494d PMID:22077920 PMCID:PMC3258304 (Completed with ARRA Funds)
  • Cao Z, Hammock BD, McCoy MR, Rogawski MA, Lein PJ, Pessah IN. 2012. Tetramethylenedisulfotetramine alters Ca2+ dynamics in cultured hippocampal neurons: Mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. J Toxicol Sci 130(2):362-372. doi:10.1093/toxsci/kfs244 PMID:22889812 PMCID:PMC3529644
  • Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos G, Schebb N, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN. 2012. Triclosan impairs excitation-contraction coupling and Ca2+ dynamics in striated muscle. Proc Natl Acad Sci U S A 109(35):14158-14163. doi:10.1073/pnas.1211314109 PMID:22891308 PMCID:PMC3435154
  • Eiserich JP, Yang J, Morrissey BM, Hammock BD, Cross CE. 2012. Omics approaches in cystic fibrosis research: A focus on oxylipin profiling in airway secretions. Ann N Y Acad Sci 1259:1-9. doi:10.1111/j.1749-6632.2012.06580.x PMID:22758630 PMCID:PMC3403728
  • Han J, Sudheendra L, Kim H, Gee SJ, Hammock BD, Kennedy IM. 2012. Ultrasensitive on-chip immunoassays with a nanoparticle-assembled photonic crystal. ACS Nano 6(10):8570-8582. doi:10.1021/nn301656c PMID:22957818 PMCID:PMC3479307
  • Inceoglu AB, Clifton HL, Yang J, Hegedus C, Hammock BD, Schaefer S. 2012. Inhibition of soluble epoxide hydrolase limits niacin-induced vasodilation in mice. J Cardiovasc Pharmacol 60:70-75. doi:10.1097/FJC.0b013e3182580a5d PMID:22526297 PMCID:PMC3396292
  • Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb N, Hwang SH, Morisseau C, Haj FG, Hammock BD. 2012. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of Type I Diabetes. Proc Natl Acad Sci U S A 109(28):11390-11395. doi:10.1073/pnas.1208708109 PMID:22733772 PMCID:PMC3396532
  • Kim H, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD, McCoy MR. 2012. Isolation of alpaca anti-hapten heavy chain single domain antibodies for development of sensitive immunoassay. Anal Chem 84(2):1165-1171. doi:10.1021/ac2030255 PMID:22148739 PMCID:PMC3264785
  • Kim H, McCoy MR, Majkova Z, Dechant JE, Gee SJ, Tabares-da Rosa S, Gonzalez-Sapienza GG, Hammock BD. 2012. Correction to isolation of alpaca antihapten heavy chain single domain antibodies for development of sensitive immunioassay. Anal Chem 84(15):6919–6919. doi:10.1021/ac301927h PMID:22830304 PMCID:PMC3460544
  • Kim I, Nishi K, Kasagami T, Morisseau C, Liu J, Tsai H, Hammock BD. 2012. Biologically active ester derivatives as potent inhibitors of the soluble epoxide hydrolase. Bioorg Med Chem Lett 22(18):5889-5892. doi:10.1016/j.bmcl.2012.07.074 PMID:22901393 PMCID:PMC3432147
  • Lin Y, Ubels JL, Schotanus MP, Yin Z, Pintea V, Hammock BD, Watsky MA. 2012. Enhancement of vitamin D metabolites in the eye following vitamin D3 supplementation and UV-B irradiation. Curr Eye Res 37(10):871-878. doi:10.3109/02713683.2012.688235 PMID:22632164 PMCID:PMC3572765
  • McCoy MR, Yang Z, Fu X, Ahn K, Gee SJ, Bom DC, Zhong P, Chang D, Hammock BD. 2012. Monitoring of total type II pyrethroid pesticides in citrus oils and water by converting to a common product 3-phenoxybenzoic acid. J Agric Food Chem 60:5065-5070. doi:10.1021/jf2051653 PMID:22486225 PMCID:PMC3412423
  • Morisseau C, Schebb N, Dong H, Ulu A, Aronov PA, Hammock BD. 2012. Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids. Biochem Biophys Res Commun 419:796-800. doi:10.1016/j.bbrc.2012.02.108 PMID:22387545 PMCID:PMC3313618
  • Qiu H, Liu J, Wei D, Li N, Yamoah EN, Hammock BD, Chiamvimonvat N. 2012. Cardiac-generated prostanoids mediate cardiac myocyte apoptosis after myocardial ischaemia. Cardiovascular Research 95(3):336-345. doi:10.1093/cvr/cvs191 PMID:22707158 PMCID:PMC3400359
  • Schebb N, Ahn K, Dong H, Gee SJ, Hammock BD. 2012. Whole blood is the sample matrix of choice for monitoring systemic triclocarbon levels. Chemosphere 87(7):825-827. doi:10.1016/j.chemosphere.2011.12.077 PMID:22273184 PMCID:PMC3538789 (Completed with ARRA Funds)
  • Schebb N, Buchholz BA, Hammock BD, Rice RH. 2012. Metabolism of the antibacterial triclocarban by human epidermal keratinocytes to yield protein adducts. J Biochem Mol Toxicol 26(6):230-234. doi:10.1002/jbt.21411 PMID:22711420 PMCID:PMC3522462
  • Schebb N, Franze B, Maul R, Ranganathan A, Hammock BD. 2012. In Vitro Glucuronidation of the Antibacterial Triclocarban and Its Oxidative Metabolites. Drug Metab Dispos 40:25-31. doi:10.1124/dmd.111.042283 PMID:21953915 PMCID:PMC3250046 (Completed with ARRA Funds)
  • Thiphom S, Prapamontol T, Chantara S, Mangklabruks A, Suphavilai C, Ahn K, Gee SJ, Hammock BD. 2012. An enzyme-linked immunosorbent assay for detecting 3-phenoxybenzoic acid in plasma and its application to farmers and consumers. Analytical Methods 4:3772-3778. doi:10.1039/c2ay25642h PMID:23667388 PMCID:PMC3646417
  • Yang J, Eiserich JP, Cross CE, Morrissey BM, Hammock BD. 2012. Metabolomic profiling of regulatory lipid mediators in sputum from adult cystic fibrosis patients. Free Radic Biol Med 53(1):160-171. doi:10.1016/j.freeradbiomed.2012.05.001 PMID:22580336 PMCID:PMC3412514
  • Yao H, Liu J, Samra AI, Kamita SG, Cornel AJ, Hammock BD, Huang H. 2012. Development of pyrethroid-like fluorescent substrates for glutathione S-transferase. Anal Biochem 431:77-83. doi:10.1016/j.ab.2012.09.011 PMID:23000005 PMCID:PMC3489985
  • Yueh MF, Li T, Evans RM, Hammock BD, Tukey RH. 2012. Triclocarban Mediates Induction of Xenobiotic Metabolism through Activation of the Constitutive Androstane Receptor and the Estrogen Receptor Alpha. PLoS One 7(6):e37705. doi:10.1371/journal.pone.0037705 PMID:22761658 PMCID:PMC3376094 (Completed with ARRA Funds)
  • Zhang W, Yang AL, Liao J, Li H, Dong H, Chung Y, Bai H, Matkowskyj KA, Hammock BD, Yang G. 2012. Soluble epoxide hydrolase gene deficiency or inhibition attenuates chronic active inflammatory bowel disease in IL-10(-/-) mice. Dig Dis 57(10):2580-2591. doi:10.1007/s10620-012-2217-1 PMID:22588244 PMCID:PMC3664520
  • Zivkovic AM, Yang J, Georgi K, Hegedus C, Nording ML, O'Sullivan A, German JB, Hogg RJ, Weiss RH, Bay C, Hammock BD. 2012. Serum oxylipin profiles in lgA nephropathy patients reflect kidney functional alterations. Metabolomics 8(6):1102-1113. doi:10.1007/s11306-012-0417-5 PMID:23833568 PMCID:PMC3700377
  • Zolkowska D, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA. 2012. Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. J Pharmacol Exp Ther 341(2):435-446. doi:10.1124/jpet.111.190579 PMID:22328574 PMCID:PMC3336809

2011

2010

  • Alihosseini F, Lango J, Ju K, Hammock BD, Sun G. 2010. Mutation of bacterium Vibrio gazogenes for selective preparation of colorants. Biotechnol Prog 26(2):352-360. doi:10.1002/btpr.346 PMID:19902486 PMCID:PMC2864118
  • Baumann A, Lohmann W, Rose TE, Ahn K, Hammock BD, Karst U, Schebb N. 2010. Electrochemistry-mass spectrometry unveils the formation of reactive triclocarban metabolites. Drug Metab Dispos 38(12):2130-2138. doi:10.1124/dmd.110.034546 PMID:20861155 PMCID:PMC2993458 (Completed with ARRA Funds)
  • Carlomagno M, Matho C, Cantou G, Sanborn JR, Last JA, Hammock BD, Roel A, Gonzalez D, Gonzalez-Sapienza GG. 2010. A Clomazone Immunoassay To Study the Environmental Fate of the Herbicide in Rice (Oryza sativa) Agriculture. J Agric Food Chem 58(7):4367-4371. doi:10.1021/jf9043259 PMID:20302341 PMCID:PMC2878771
  • Chabova VC, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kujal P, Vernerova Z, Vanourkova Z, Kopkan L, Kramer HJ, Imig JD, Hammock BD, Vaneckova I, Cervenka L, Falck JR. 2010. Combined inhibition of 20-hydroxyeicosatetraenoic acid formation and of epoxyeicosatrienoic acids degradation attenuates hypertension and hypertension-induced end-organ damage in Ren-2 transgenic rats. Clin Sci (Lond) 118(10):617-632. doi:10.1042/CS20090459 PMID:20050826 PMCID:PMC2854172
  • Garcia-Nieto E, Nichkova MJ, Yanez L, Costilla-Salazar R, Torres-Dosal A, Gee SJ, Hammock BD, Juarez-Santacruz L, Diaz-Barriga F. 2010. Assessment of Dioxin-Like Soil Contamination in Mexico by Enzyme-Linked Immunosorbent Assay. Arch Environ Contam Toxicol 58(4):918-926. doi:10.1007/s00244-009-9422-8 PMID:20091164 PMCID:PMC3033344
  • Hall LM, Kimlin M, Aronov PA, Hammock BD, Slusser J, Woodhouse L, Stephensen CB. 2010. Vitamin D intake needed to maintain target serum 25-hydroxyvitamin D concentrations in participants with low sun exposure and dark skin pigmentation is substantially higher than current recommendations. J Nutr 140(3):542-550. doi:10.3945/jn.109.115253 PMID:20053937 PMCID:PMC2821886
  • Kim H, Rossotti MA, Ahn K, Gonzalez-Sapienza GG, Gee SJ, Musker R, Hammock BD. 2010. Development of a noncompetitive phage anti-immunocomplex assay for brominated diphenyl ether 47. Anal Biochem 401(1):38-46. doi:10.1016/j.ab.2010.01.040 PMID:20152791 PMCID:PMC2861364
  • Kubala L, Schmelzer KR, Klinke A, Kolarova H, Baldus S, Hammock BD, Eiserich JP. 2010. Modulation of arachidonic and linoleic acid metabolites in myeloperoxidase-deficient mice during acute inflammation. Free Radical Biology & Medicine,. Free Radic Biol Med 48(10):1311-1320. doi:10.1016/j.freeradbiomed.2010.02.010 PMID:20156554 PMCID:PMC2856720
  • Liu J, Li N, Yang J, Li N, Qiu H, Ai D, Chiamvimonvat N, Zhu Y, Hammock BD. 2010. Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events. Proc Natl Acad Sci U S A 107(39):17017-17022. doi:10.1073/pnas.1011278107 PMID:20837537 PMCID:PMC2947894
  • Morisseau C, Inceoglu B, Schmelzer KR, Tsai H, Jinks SL, Hegedus CM, Hammock BD. 2010. Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids. J Lipid Res 51:3481-3490. doi:10.1194/jlr.M006007 PMID:20664072 PMCID:PMC2975720
  • Nording ML, Yang J, Hegedus CM, Bhushan A, Kenyon NJ, Davis CE, Hammock BD. 2010. Endogenous levels of five fatty acid metabolites in exhaled breath condensate to monitor asthma by high-performance liquid chromatography: Electrospray tandem mass spectrometry. IEEE/ACM Trans Comput Biol Bioinform 10(1):123-130. doi:10.1109/JSEN.2009.2035736 PMID:21103452 PMCID:PMC2981865
  • Rayo J, Munoz L, Rosell G, Hammock BD, Guerrero A, Luque FJ, Pouplana R. 2010. Reactivity versus steric effects in fluorinated ketones as esterase inhibitors: a quantum mechanical and molecular dynamics study. J Mol Model 16(11):1753-1764. doi:10.1007/s00894-010-0807-4 PMID:20676708 PMCID:PMC3014912
  • Rose TE, Morisseau C, Liu J, Inceoglu B, Jones PD, Sanborn JR, Hammock BD. 2010. 1-Aryl-3-(1-acylpiperidin-4-yl)urea inhibitors of human and murine soluble epoxide hydrolase: structure-activity relationships, pharmacokinetics, and reduction of inflammatory pain. J Med Chem 53(19):7067-7075. doi:10.1021/jm100691c PMID:20812725 PMCID:PMC3285450
  • Rossotti MA, Carlomagno M, Gonzalez-Techera A, Hammock BD, Last JA, Gonzalez-Sapienza GG. 2010. Phage anti-immunocomplex assay for clomazone: Two-site recognition increasing assay specificity and facilitating adaptation into an on-site format. Anal Chem 82(21):8838-8843. doi:10.1021/ac101476f PMID:20886819 PMCID:PMC3025275
  • Tsai H, Hwang SH, Morisseau C, Yang J, Jones PD, Kasagami T, Kim I, Hammock BD. 2010. Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs. European Journal of Pharmaceutical Sciences 40(3):222-238. doi:10.1016/j.ejps.2010.03.018 PMID:20359531 PMCID:PMC3285443
  • Wang Y, Ulu A, Zhang L, Hammock BD. 2010. Soluble epoxide hydrolase in atherosclerosis. Curr Atheroscler Rep 12(3):174-183. doi:10.1007/s11883-010-0108-5 PMID:20425256 PMCID:PMC2857794

2009

  • Ahn K, Gee SJ, Tsai H, Bennett DH, Nishioka M, Blum A, Fishman E, Hammock BD. 2009. Immunoassay for monitoring environmental and human exposure to the polybrominated diphenyl ether BDE-47. Environ Sci Technol 43(20):7784-7790. doi:10.1021/es9009037 PMID:19921894 PMCID:PMC3528349
  • Ai D, Pang W, Li N, Xu M, Jones PD, Yang J, Zhang Y, Chiamvimonvat N, Shyy JY, Hammock BD, Zhu Y. 2009. Soluble epoxide hydrolase plays an essential role in angiotensin II-induced cardiac hypertrophy. Proc Natl Acad Sci U S A 106(2):564-569. doi:10.1073/pnas.0811022106 PMID:19126686 PMCID:PMC2626743
  • Barbosa-Sicard E, Fromel T, Keseru B, Brandes RP, Morisseau C, Hammock BD, Braun T, Kruger M, Fleming I. 2009. Inhibition of the Soluble Epoxide Hydrolase by Tyrosine Nitration. J Biol Chem 284:28156-28163. doi:10.1074/jbc.M109.054759 PMID:19704161 PMCID:PMC2788866
  • Chawengsub Y, Gauthier KM, Nithipatikom K, Hammock BD, Falck JR, Narsimhaswamy D, Campbell WB. 2009. Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries. J Biol Chem 284(45):31280-31290. doi:10.1074/jbc.M109.025627 PMID:19737933 PMCID:PMC2781526
  • Falck JR, Kodela R, Manne R, Atcha KR, Puli N, Dubasi N, Manthati VL, Capdevila JH, Yi X, Goldman DH, Morisseau C, Hammock BD, Campbell WB. 2009. 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition. J Med Chem 52(16):5069-5075. doi:10.1021/jm900634w PMID:19653681 PMCID:PMC2888647
  • Huang H, Tanaka H, Hammock BD, Morisseau C. 2009. Novel and highly sensitive fluorescent assay for leucine aminopeptidases. Anal Biochem 391(1):11-16. doi:10.1016/j.ab.2009.05.004 PMID:19433052 PMCID:PMC2748848
  • Inceoglu AB, Waite T, Christiansen JA, McAbee RD, Kamita SG, Hammock BD, Cornel AJ. 2009. A rapid luminescent assay for measuring cytochrome P450 activity in individual larval Culex pipiens complex mosquitoes (Diptera: Culicidae). Journal of Medical Entomology 46(1):83-92. doi:10.1603/033.046.0111 PMID:19198521 PMCID:PMC3522461
  • Kasagami T, Kim I, Tsai H, Nishi K, Hammock BD, Morisseau C. 2009. Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities. Bioorg Med Chem Lett 19(6):1784-1789. doi:10.1016/j.bmcl.2009.01.069 PMID:19216074 PMCID:PMC2900318
  • Kim HJ, Ahn K, Gonzalez-Techera A, Gonzalez-Sapienza GG, Gee SJ, Hammock BD. 2009. Magnetic bead-based phage anti-immunocomplex assay (PHAIA) for the detection of the urinary biomarker 3-phenoxybenzoic acid to assess human exposure to pyrethroid insecticides. Anal Biochem 386(1):45-52. doi:10.1016/j.ab.2008.12.003 PMID:19101498 PMCID:PMC2863013
  • Li N, Liu J, Timofeyev V, Qiu H, Hwang SH, Tuteja D, Lu L, Yang J, Mochida H, Low R, Hammock BD, Chiamvimonvat N. 2009. Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches. J Mol Cell Cardiol 47(6):835-845. doi:10.1016/j.yjmcc.2009.08.017 PMID:19716829 PMCID:PMC3290524
  • Liu J, Park S, Morisseau C, Hwang SH, Hammock BD, Weiss RH. 2009. Sorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo. Mol Cancer Ther 8(8):2193-2203. doi:10.1158/1535-7163.MCT-09-0119 PMID:19671760 PMCID:PMC2728155
  • Liu J, Tsai H, Hwang SH, Jones PD, Morisseau C, Hammock BD. 2009. Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation. Br J Pharmacol 156(2):284-296. doi:10.1111/j.1476-5381.2008.00009.x PMID:19154430 PMCID:PMC2697843
  • Lu C, Schoenfeld R, Shan Y, Tsai H, Hammock BD, Cortopassi GA. 2009. Frataxin deficiency induces Schwann cell inflammation and death. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1792(11):1052-1061. doi:10.1016/j.bbadis.2009.07.011 PMID:19679182 PMCID:PMC3563672
  • Luria A, Morisseau C, Tsai H, Yang J, Inceoglu B, De Taeye B, Wiest MM, German JB, Hammock BD, Watkins SM. 2009. Alteration in plasma testosterone levels in male mice lacking soluble epoxide hydrolase. Am J Physiol Endocrinol Metab 297(2):E375-E383. doi:10.1152/ajpendo.00131.2009 PMID:19458064 PMCID:PMC2724109
  • Ma Z, Dosev D, Nichkova MJ, Dumas RK, Gee SJ, Hammock BD, Kennedy IM. 2009. Synthesis and characterization of multifunctional silica core-shell nanocomposites with magnetic and fluorescent functionalities. Journal of Magnetism and Magnetic Materials 321(10):1368-1371. doi:10.1016/j.jmmm.2009.02.040 PMID:20336173 PMCID:PMC2844650
  • Ma Z, Dosev D, Nichkova MJ, Gee SJ, Hammock BD, Kennedy IM. 2009. Synthesis and bio-functionalization of multifunctional magnetic Fe3O4@Y2O3:Eu nanocomposites. Journal of Materials Chemistry 19:4695-4700. doi:10.1039/B901427F PMID:20357905 PMCID:PMC2847302
  • Matveeva EG, Morisseau C, Goodrow MH, Mullin C, Hammock BD. 2009. Tryptophan fluorescence quenching by enzyme inhibitors as a tool for enzyme active site structure investigation: epoxide hydrolase. Curr Pharm Biotechnol 10(6):589-599. doi:10.2174/138920109789069260 PMID:19619123 PMCID:PMC2861369
  • Morisseau C, Merzlikin O, Lin A, He G, Feng W, Padilla I, Denison MS, Pessah IN, Hammock BD. 2009. Toxicology in the fast lane: application of high-throughput bioassays to detect modulation of key enzymes and receptors. Environ Health Perspect 117(12):1867-1872. doi:10.1289/ehp.0900834 PMID:20049205 PMCID:PMC2799460
  • Nichkova MJ, Fu X, Yang Z, Zhong P, Sanborn JR, Chang D, Gee SJ, Hammock BD. 2009. Immunochemical Screening of Pesticides (Simazine and Cypermethrin) in Orange Oil. J Agric Food Chem 57(13):56735679. doi:10.1021/jf900652a PMID:19526986 PMCID:PMC3033343
  • Parrish AR, Chen G, Burghardt RC, Watanabe T, Hammock BD, Morisseau C. 2009. Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase. Cell Biol Toxicol 25(3):217-225. doi:10.1007/s10565-008-9071-0 PMID:18386137 PMCID:PMC3033346
  • Shen S, Zhang F, Zeng S, Tian Y, Chai X, Gee SJ, Hammock BD, Zheng J. 2009. Development of enantioselective polyclonal antibodies to detect styrene oxide protein adducts. Anal Chem 81(7):2668-2677. doi:10.1021/ac8023262 PMID:19245253 PMCID:PMC3463234
  • Yang J, Schmelzer KR, Georgi K, Hammock BD. 2009. Quantitative profiling method for oxylipin metabolome by liquid chromatography electrospray ionization tandem mass spectrometry. Anal Chem 81(19):8085-8093. doi:10.1021/ac901282n PMID:19715299 PMCID:PMC3290520

2008

  • Aronov PA, Hall LM, Dettmer K, Stephensen CB, Hammock BD. 2008. Metabolic profiling of major vitamin D metabolites using Diels-Alder derivatization and ultra-performance liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem 391(5):1917-1930. doi:10.1007/s00216-008-2095-8 PMID:18437365 PMCID:PMC3587164
  • Aronova S, Wedaman K, Aronov PA, Fontes K, Ramos K, Hammock BD, Powers T. 2008. Regulation of ceramide biosynthesis by TOR complex 2. Cell Metab 7(2):148-158. doi:10.1016/j.cmet.2007.11.015 PMID:18249174 PMCID:PMC3882310
  • Barbosa-Sicard E, Popp R, Fisslthaler B, Hammock BD, Falck JR, Busse R, Fleming I, Keseru B, Dietrich A, Gudermann T, Weissmann N. 2008. Epoxyeicosatrienoic acids and the soluble epoxide hydrolase are determinants of pulmonary artery pressure and the acute hypoxic pulmonary vasoconstrictor response. FASEB J 22(12):4306-4315. doi:10.1096/fj.08-112821 PMID:18725458 PMCID:PMC2614611
  • Bradbury JA, Graves J, Degraff LM, Zhao X, Imig JD, Pedersen TL, Newman JW, Hammock BD, Conley AJ, Korach KS, Zeldin DC, Athirakul K, Ma J, Zhao Y, Couse JF, Quigley R, Harder DR, Coffman TM. 2008. Increased blood pressure in mice lacking cytochrome P450 2J5. FASEB J 22(12):4096-4108. doi:10.1096/fj.08-114413 PMID:18716027 PMCID:PMC2614614
  • Chawengsub Y, Aggarwal N, Nithipatikom K, Gauthier KM, Anjaiah S, Hammock BD, Falck JR, Campbell WB. 2008. Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta. Am J Physiol Heart Circ Physiol 294(3):1348-56.
  • Chen J, Ahn K, Gee NA, Ahmed MI, Duleba AJ, Zhao L, Gee SJ, Hammock BD, Lasley BL. 2008. Triclocarban enhances testosterone action: a new type of endocrine disruptor?. Endocrinology 149(3):1173-1179. doi:10.1210/en.2007-1057 PMID:18048496 PMCID:PMC2275366
  • Chen J, Ahn K, Zhao B, Denison MS, Lasley BL, Pessah IN, Kültz D, Chang DP, Gee SJ, Hammock BD, Cherednichenko G. 2008. In Vitro Biologic Activities of the Antimicrobials Triclocarban, Its Analogs, and Triclosan in Bioassay Screens: Receptor-Based Bioassay Screens. Environ Health Perspect 116:1203-1210. doi:10.1289/ehp.11200 PMID:18795164 PMCID:PMC2535623
  • Corenblum MJ, Wise VE, Georgi K, Hammock BD, Doris PA, Fornage M. 2008. Altered soluble epoxide hydrolase gene expression and function and vascular disease risk in the stroke-prone spontaneously hypertensive rat. Hypertension 51(2):567-73. PMID:18086949
  • Dreisbach AW, Rice JC, Japa S, Newman JW, Sigel A, Gill R, Hess AE, Cemo AC, Fonseca JP, Hammock BD, Lertora JJ, Hamm LL. 2008. Salt loading increases urinary excretion of linoleic acid diols and triols in healthy human subjects. Hypertension 51:755-761. PMID:18227407
  • Enayetallah AE, Luria A, Luo B, Tsai H, Sura P, Hammock BD, Grant DF. 2008. Opposite regulation of cholesterol levels by the phosphatase and hydrolase domains of soluble epoxide hydrolase. J Biol Chem 283(52):36592-36598. doi:10.1074/jbc.M806315200 PMID:18974052 PMCID:PMC2605982
  • Fife KL, Liu Y, Schmelzer KR, Tsai H, Kim I, Morisseau C, Hammock BD, Kroetz DL. 2008. Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. J Pharmacol Exp Ther 327(3):707-715. doi:10.1124/jpet.108.142398 PMID:18815352 PMCID:PMC2761654
  • Gonzalez-Techera A, Umpierrez-Failache M, Cardozo S, Obal G, Last JA, Gee SJ, Hammock BD, Gonzalez-Sapienza GG, Pritsch O. 2008. High-throughput method for ranking the affinity of peptide ligands selected from phage display libraries. Bioconjug Chem 19(5):993-1000. doi:10.1021/bc700279y PMID:18393454 PMCID:PMC2863005
  • Gross GJ, Gauthier KM, Moore J, Falck JR, Hammock BD, Campbell WB, Nithipatikom K. 2008. Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. Am J Physiol Heart Circ Physiol 294(6):H2838-H2844. doi:10.1152/ajpheart.00186.2008 PMID:18441205 PMCID:PMC2863006
  • Harris TR, Aronov PA, Hammock BD. 2008. Soluble epoxide hydrolase homologs in Strongylocentrotus purpuratus suggest a gene duplication event and subsequent divergence. DNA Cell Biol 27(9):467-477. doi:10.1089/dna.2008.0751 PMID:18554159 PMCID:PMC2858585
  • Hwang H, Park E, Young TM, Hammock BD. 2008. Occurrence of endocrine-disrupting chemicals in indoor dust. Sci Total Environ 404(1):26-35. doi:10.1016/j.scitotenv.2008.05.031 PMID:18632138 PMCID:PMC2858057
  • Inceoglu B, Jinks SL, Ulu A, Hegedus CM, Georgi K, Schmelzer KR, Wagner KM, Jones PD, Morisseau C, Hammock BD. 2008. Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways. Proc Natl Acad Sci U S A 105(48):18901-18906. doi:10.1073/pnas.0809765105 PMID:19028872 PMCID:PMC2596245
  • Jiang H, Zhu AG, Mamczur M, Morisseau C, Hammock BD, Falck JR, McGiff JC. 2008. Hydrolysis of cis- and trans-epoxyeicosatrienoic acids by rat red blood cells. J Pharmacol Exp Ther 326(1):330-337. doi:10.1124/jpet.107.134858 PMID:18445784 PMCID:PMC2732189
  • Kim HJ, Gonzalez-Techera A, Gonzalez-Sapienza GG, Ahn K, Gee SJ, Hammock BD. 2008. Phage-borne peptidomimetics accelerate the development of polyclonal antibody-based heterologous immunoassays for the detection of pesticide metabolites. Environ Sci Technol 42(6):2047-53. doi:10.1021/es702219a PMID:18409635
  • Morisseau C, Hammock BD. 2008. Gerry Brooks and epoxide hydrolases: four decades to a pharmaceutical. Pest Manag Sci 64(6):594-609. doi:10.1002/ps.1583 PMID:18383502
  • Morisseau C, Newman JW, Wheelock CE, Hill T, Morin D, Buckpitt AR, Hammock BD. 2008. Development of metabolically stable inhibitors of Mammalian microsomal epoxide hydrolase. Chem Res Toxicol 21(4):951-957. doi:10.1021/tx700446u PMID:18363382
  • Park E, Duarte Tagles H, Gee SJ, Hammock BD, Lee K, Schenker MB. 2008. Recruiting strategy and 24-hour biomonitoring of paraquat in agricultural workers. J Agromedicine 13(4):207-17.
  • Tanaka H, Kamita SG, Wolf NM, Harris TR, Wu Z, Morisseau C, Hammock BD. 2008. Transcriptional regulation of the human soluble epoxide hydrolase gene EPHX2. Biochim Biophys Acta 1779(1):17-27. doi:10.1016/j.bbagrm.2007.11.005 PMID:18078836 PMCID:PMC2699939
  • Van Emon JM, Chuang J, Lordo RA, Schrock ME, Nichkova MJ, Gee SJ, Hammock BD. 2008. An enzyme-linked immunosorbent assay for the determination of dioxins in contaminated sediment and soil samples. Chemosphere 72(1):95-103. doi:10.1016/j.chemosphere.2008.01.012 PMID:18313102 PMCID:PMC2858573
  • Wheelock CE, Forshed J, Goto S, Hammock BD, Newman JW. 2008. Effects of pyridine exposure upon structural lipid metabolism in Swiss Webster mice. Chem Res Toxicol 21(3):583-590. doi:10.1021/tx7002454 PMID:18251509
  • Wheelock CE, Nishi K, Jones PD, Colvin ME, Olmstead MM, Hammock BD. 2008. Influence of sulfur oxidation state and steric bulk upon trifluoromethyl ketone (TFK) binding kinetics to carboxylesterases and fatty acid amide hydrolase (FAAH). Bioorg Med Chem 16(4):2114-2130. doi:10.1016/j.bmc.2007.10.081 PMID:18023188 PMCID:PMC2720161
  • Wheelock CE, Phillips BM, Miller JL, Miller MG, Hammock BD. 2008. Applications of carboxylesterase activity in environmental monitoring and Toxicity Identification Evaluations (TIEs). Rev Environ Contam Toxicol 195:doi:10.1007/978-0-387-77030-7

2007

  • Ahn K, Lohstroh PN, Gee SJ, Gee NA, Lasley BL, Hammock BD. 2007. High-throughput automated luminescent magnetic particle-based immunoassay to monitor human exposure to pyrethroid insecticides. Anal Chem 79(23):8883-8890. doi:10.1021/ac070675l PMID:17983205
  • Ai D, Fu Y, Guo D, Tanaka H, Wang N, Tang C, Hammock BD, Shyy JY, Zhu Y. 2007. Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo. Proc Natl Acad Sci U S A 104(21):9018-23. PMID:17495027
  • Akatsuka T, Ishikawa T, Kobayashi N, Saito T, Shindo M, Yamauchi M, Kurokohchi K, Miyazawa H, Duan H, Matsunaga T, Komoda T, Morisseau C, Hammock BD. 2007. Autoantibody response to microsomal epoxide hydrolase in hepatitis C and A. J Autoimmun 28(1):7-18. doi:10.1016/j.jaut.2006.12.005 PMID:17296285 PMCID:PMC1892246
  • Chen J, Ahn K, Gee SJ, Gee NA, Hammock BD, Lasley BL. 2007. Antiandrogenic properties of parabens and other phenolic containing small molecules in personal care products. Toxicol Appl Pharmacol 221(a):278-284.
  • Chiamvimonvat N, Ho C, Tsai H, Hammock BD. 2007. The soluble epoxide hydrolase as a pharmaceutical target for hypertension. J Cardiovasc Pharmacol 50:225-237.
  • Chiappe C, Leandri E, Hammock BD, Morisseau C. 2007. Effect of ionic liquids on epoxide hydrolase-catalyzed synthesis of chiral 1,2-diols. Green Chem 2007(9):162-168. doi:10.1039/b612106c PMID:18160974 PMCID:PMC2153531
  • Dettmer K, Aronov PA, Hammock BD. 2007. Mass spectrometry-based metabolomics. Mass Spectrom Rev 26(1):51-78.
  • Dettmer K, Hanna D, Whetstone P, Hansen R, Hammock BD. 2007. Autism and urinary exogenous neuropeptides: development of an on-line SPE-HPLC-tandem mass spectrometry method to test the opioid excess theory. Anal Bioanal Chem 388:1643-1651.
  • Devonshire AL, Heidari R, Huang H, Hammock BD, Russell RJ, Oakeshott JG. 2007. Hydrolysis of individual isomers of fluorogenic pyrethroid analogs by mutant carboxylesterases from Lucilia cuprina. Insect Biochem Mol Biol 37:891-902.
  • Dosev D, Nichkova MJ, Dumas RK, Gee SJ, Hammock BD, Liu K, Kennedy IM. 2007. Magnetic/luminescent core/shell particles synthesized by spray pyrolysis and their application in immunoassays with internal standard. Nanotechnology 18(5):055102(6pp). PMID:18974844
  • Endsley MP, Aggarwal N, Isbell MA, Wheelock CE, Hammock BD, Flack JR, Nithipatikom K, Campbell WB. 2007. Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: location, hydrolysis and 12-lipoxygenase metabolism. Int J Cancer 121:984-991.
  • Fleming I, Rueben A, Popp R, Fisslthaler B, Sander A, Haendeler J, Falck JR, Morisseau C, Hammock BD, Busse R. 2007. Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells. Arteriosclerosis, Thrombosis and Vascular Biology 27(12):2612-8.
  • Gonzalez-Techera A, Kim HJ, Gee SJ, Last JA, Hammock BD. 2007. Polyclonal antibody-based noncompetitive immunoassay for small analytes developed with short peptide loops isolated from phage libraries. Anal Chem 79(23):9191-9196. doi:10.1021/ac7016713 PMID:17973501 PMCID:PMC2556293
  • Gonzalez-Techera A, Vanrell L, Last JA, Hammock BD, Gonzalez-Sapienza GG. 2007. Phage anti-immune complex assay: general strategy for noncompetitive immunodetection of small molecules. Anal Chem 79(20):7799-7806. doi:10.1021/ac071323h PMID:17845007 PMCID:PMC2519879
  • Hillard CJ, Ho WS, Thompson J, Gauthier KM, Wheelock CE, Huang H, Hammock BD. 2007. Inhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. Br J Pharmacol 152(5):691-8. PMID:17891162
  • Huang H, Nishi K, Tsai H, Hammock BD. 2007. Development of highly sensitive fluorescent assays for fatty acid amide hydrolase. Anal Biochem 363(1):12-21. PMID:17291440
  • Hwang SH, Tsai H, Liu J, Morisseau C, Hammock BD. 2007. Orally bioavailable potent soluble epoxide hydrolase inhibitors. J Med Chem 50(16):3825-3840. doi:10.1021/jm070270t PMID:17616115 PMCID:PMC2596069
  • Inceoglu B, Schmelzer KR, Morisseau C, Jinks SL, Hammock BD. 2007. Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs). Prostaglandins Other Lipid Mediat 82(1-4):42-49. PMID:17164131
  • Kim H, Gee SJ, Li QX, Hammock BD. 2007. Noncompetitive Fluorescent Immunoassay for the Detection of the Human Urinary Biomarker 3-Phenoxybenzoic Acid with Bench Top Immunosensor KinExATM 3000. Chapter 11in: Rational Environmental Management of Agrochemicals: Risk Assessment, Monitoring, and Remedial Action. pp.171185.
  • Kim HJ, Ahn K, Ma S, Gee SJ, Hammock BD. 2007. Development of sensitive immunoassays for the detection of the glucuronide conjugate of 3-phenoxybenzyl alcohol, a putative human urinary biomarker for pyrethroid exposure. J Agric Food Chem 55(10):3750-7. PMID:17455946
  • Kim I, Nishi K, Tsai H, Bradford T, Koda Y, Watanabe T, Morisseau C, Blanchfield J, Toth I, Hammock BD. 2007. Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase. Bioorg Med Chem 15(1):312-23. PMID:17046265
  • Kim I, Tsai H, Nishi K, Kasagami T, Morisseau C, Hammock BD. 2007. 1,3-disubstituted ureas functionalized with ether groups are potent inhibitors of the soluble epoxide hydrolase with improved pharmacokinetic properties. J Med Chem 50(21):5217-5226. doi:10.1021/jm070705c PMID:17894481 PMCID:PMC2543935
  • Loch D, Hoey A, Morisseau C, Hammock BD, Brown L. 2007. Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble epoxide hydrolase. Cell Biochem Biophys 47:87-97. PMID:17406062
  • Luria A, Weldon SM, Kabcenell AK, Ingraham RH, Matera D, Jiang H, Gill R, Morisseau C, Newman JW, Hammock BD. 2007. Compensatory mechanism for homeostatic blood pressure regulation in Ephx2 gene-disrupted mice. J Biol Chem 282(5):2891-8. PMID:17135253
  • Newman JW, Kaysen GA, Hammock BD, Shearer GC. 2007. Proteinuria increases oxylipid concentrations in VLDL and HDL, but not LDL particles in the rat. J Lipid Res 48:1792-1800.
  • Nichkova MJ, Dosev D, Davies AE, Gee SJ, Kennedy IM, Hammock BD. 2007. Multiplexed immunoassays for biomonitoring of exposure to agrochemicals using quantum dots as fluorescent reporters. Proceedings of SPIE 6448:644817-1. doi:10.1117/12.699231
  • Nichkova MJ, Dosev D, Davies AE, Gee SJ, Kennedy IM, Hammock BD. 2007. Quantum Dots as Reporters in Multiplexed Immunoassays for Biomarkers of Exposure to Agrochemicals. Anal Lett 40(7):1423-1433. doi:10.1080/00032710701327088 PMID:19079795 PMCID:PMC2600528
  • Nichkova MJ, Dosev D, Gee SJ, Hammock BD, Kennedy IM. 2007. Multiplexed immunoassays for proteins using magnetic luminescent nanoparticles for internal calibration. Anal Biochem 369(a):34-40. PMID:17681270
  • Park E, Mak SK, Hammock BD, Kültz D. 2007. Evaluation of cytotoxicity attributed to thimerosal on murine and human kidney cells. J Toxicol Environ Health A 70(24):2092-5. PMID:18049999
  • Park E, Mak SK, Kültz D, Hammock BD. 2007. Determination of cytotoxicity of nephrotoxins on murine and human kidney cell lines. J Environ Sci Health B 43:71-74.
  • Pedersen TL, Grekin RJ, Hammock BD, Ball DL, Vollmer A. 2007. Heparin, lipoproteins, and oxygenated fatty acids in blood: a cautionary note. Prostaglandins Leukot Essent Fatty Acids 77(5-6):363-366. doi:10.1016/j.plefa.2007.10.012 PMID:18036802 PMCID:PMC2705328
  • Thompson DA, Hammock BD. 2007. Dihydroxyoctadecamonoenoate esters inhibit the neutrophil respiratory burst. J Biosci 32(2):279-91.
  • Wadkins RM, Hyatt JL, Edwards CC, Tsurkan L, Redinbo MR, Wheelock CE, Jones PD, Hammock BD, Potter PM. 2007. Analysis of mammalian carboxylesterase inhibition by trifluoromethylketone-containing compounds. Mol Pharmacol 71(3):713-723. PMID:17167034
  • Wheelock CE, Goto S, Hammock BD, Newman JW. 2007. Clofibrate-induced changes in the liver, heart, brain and white adipose lipid metabolome of Swiss-Webster mice. Metabolomics 3:137-145.
  • Yuan W, Chung JS, Gee SJ, Hammock BD, Zheng J. 2007. Development of polyclonal antibodies for the detection of styrene oxide modified proteins. Chem Res Toxicol 20(2):316-321. doi:10.1021/tx600340c PMID:17266334 PMCID:PMC2565645
  • Zhang W, Koerner IP, Noppens R, Grafe M, Tsai H, Morisseau C, Luria A, Hammock BD, Falck JR, Alkayed NJ. 2007. Soluble epoxide hydrolase: a novel therapeutic target in stroke. J Cereb Blood Flow Metab 27(12):1931-40.

2006

  • Ahn K, Ma S, Tsai H, Gee SJ, Hammock BD. 2006. An immunoassay for a urinary metabolite as a biomarker of human exposure to the pyrethroid insecticide permethrin. Anal Bioanal Chem 384(3):713-722. PMID:16416099
  • Carkeet C, Dueker SR, Lango J, Buchholz BA, Miller JW, Green R, Hammock BD, Roth JR, Anderson PJ. 2006. Human vitamin B12 absorption measurement by accelerator mass spectrometry using specifically labeled 14C-cobalamin. Proc Natl Acad Sci U S A 103(15):5694-5699.
  • Cummins CM, Koivunen ME, Stephanian A, Gee SJ, Hammock BD, Kennedy IM. 2006. Application of europium(III) chelate-dyed nanoparticle labels in a competitive atrazine fluoroimmunoassay on an ITO waveguide. Biosens Bioelectron 21(7):1077-1085. PMID:16368482
  • Davis BB, Morisseau C, Newman JW, Pedersen TL, Hammock BD, Weiss RH. 2006. Attenuation of vascular smooth muscle cell proliferation by 1-cyclohexyl-3-dodecyl urea is independent of soluble epoxide hydrolase inhibition. J Pharmacol Exp Ther 316(2):815-821. PMID:16221742
  • Gomez GA, Morisseau C, Hammock BD, Christianson DW. 2006. Human soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids. Protein Sci 15(1):58-64. doi:10.1110/ps.051720206 PMID:16322563 PMCID:PMC1762130
  • Harris TR, Morisseau C, Walzem RL, Ma S, Hammock BD. 2006. The cloning and characterization of a soluble epoxide hydrolase in chicken. Poultry Science 82(2):278-287. PMID:16523628
  • Huang H, Nishi K, Gee SJ, Hammock BD. 2006. Evaluation of chiral -cyanoesters as general fluorescent substrates for screening enantioselective esterases. J Agric Food Chem 54(3):694-699.
  • Hwang SH, Morisseau C, Do ZN, Hammock BD. 2006. Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett 16(22):5773-7. PMID:16949285
  • Inceoglu B, Jinks SL, Schmelzer KR, Waite T, Kim I, Hammock BD. 2006. Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain. Life Sciences 79(24):2311-2319. PMID:16962614
  • Inceoglu B, Lango J, Whetstone P, Hammock BD. 2006. The neutralizing effect of a polyclonal antibody raised against the N-terminal eighteen-aminoacid residues of birtoxin towards the whole venom of Parabuthus transvaalicus. Toxicology 47(2):144-149. PMID:16356521
  • Jones PD, Tsai H, Do ZN, Morisseau C, Hammock BD. 2006. Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase. Bioorg Med Chem Lett 16(19):5212-5216. PMID:16870439
  • Koivunen ME, Dettmer K, Vermeulen R, Bakke B, Gee SJ, Hammock BD. 2006. Improved methods for urinary atrazine mercapturate analysisAssessment of an enzyme-linked immunosorbent assay (ELISA) and a novel liquid chromatographymass spectrometry (LCMS) method utilizing online solid phase extraction (SPE). Anal Chim Acta 572(2):180-189.
  • Larsen BT, Miura H, Hatoum OA, Campbell WB, Hammock BD, Zeldin DC, Falck JR, Gutterman DD. 2006. Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BKCa channels: implications for soluble epoxide hydrolase inhibition. Am J Pathol 290(2):H491-H499. PMID:16258029
  • Lee CR, North KE, Bray MS, Fornage M, Seubert JM, Newman JW, Hammock BD, Couper DJ, Heiss G, Zeldin DC. 2006. Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study. Hum Mol Genet 15(10):1640-1649. PMID:16595607
  • Morisseau C, Newman JW, Tsai H, Baecker PA, Hammock BD. 2006. Peptidyl-urea based inhibitors of soluble epoxide hydrolases. Bioorg Med Chem Lett 16(20):5439-5444.
  • Ng VY, Morisseau C, Falck JR, Hammock BD, Kroetz DL. 2006. Inhibition of Smooth Muscle Proliferation by Urea-Based Alkanoic Acids via Peroxisome Proliferator-Activated Receptor {alpha}Dependent Repression of Cyclin D1. Arteriosclerosis, Thrombosis and Vascular Biology 26(11):4262.
  • Nichkova MJ, Dosev D, Perron R, Gee SJ, Hammock BD, Kennedy IM. 2006. Eu3+-doped Gd2O3 nanoparticles as reporters for optical detection and visualization of antibodies patterned by microcontact printing. Anal Bioanal Chem 384(3):631-637. PMID:16416096
  • Nishi K, Huang H, Kamita SG, Kim I, Morisseau C, Hammock BD. 2006. Characterization of pyrethroid hydrolysis by the human liver carboxylesterases hCE-1 and hCE-2. Arch Biochem Biophys 445(1):115-123. PMID:16359636
  • Nording M, Nichkova MJ, Spinnel E, Persson Y, Gee SJ, Hammock BD, Haglund P. 2006. Rapid screening of dioxin-contaminated soil by accelerated solvent extraction/purification followed by immunochemical detection. Anal Bioanal Chem 385(2):357-366. PMID:16598456
  • Olearczyk JJ, Field MB, Kim I, Morisseau C, Hammock BD, Imig JD. 2006. Substituted adamantyl-urea inhibitors of the soluble epoxide hydrolase dilate mesenteric resistance vessels. J Pharmacol Exp Ther 318(3):1307-1314. PMID:16772540
  • Pokreisz P, Fleming I, Kiss L, Barbosa-Sicard E, Fisslthaler B, Falck JR, Hammock BD, Kim I, Szelid Z, Vermeersch P, Gillijns H, Pellens M, Grimminger F, van Zonneveld A, Collen D, Busse R, Janssens S. 2006. Cytochrome P450 epoxygenase gene function in hypoxic pulmonary vasoconstriction and pulmonary vascular remodeling. Hypertension 47(4):762-770. PMID:16505204
  • Schmelzer KR, Inceoglu B, Kubala L, Kim I, Jinks SL, Eiserich JP, Hammock BD. 2006. Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors. Proc Natl Acad Sci U S A 103(37):13646-13651. PMID:16950874
  • Schmelzer KR, Wheelock AM, Dettmer K, Morin D, Hammock BD. 2006. The role of inflammatory mediators in the synergistic toxicity of ozone and 1-nitronaphthalene in rat airways. Environ Health Perspect 114(9):1354-1360.
  • Seubert JM, Sinal CJ, Graves J, Degraff LM, Bradbury JA, Lee CR, Goralski K, Carey MA, Luria A, Newman JW, Hammock BD, Falck JR, Roberts H, Rockman HA, Murphy E, Zeldin DC. 2006. Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function. Circulation Research 99(4):442-450.
  • Watanabe T, Schulz D, Morisseau C, Hammock BD. 2006. High-throughput pharmacokinetic method: Cassette dosing in mice. Anal Chim Acta 559(1):37-44.
  • Wheelock AM, Miller JL, Miller MJ, Phillips BM, Huntley SA, Gee SJ, Tjeerdema RS, Hammock BD. 2006. Use of carboxylesterase activity to remove pyrethroid-associated toxicity to Ceriodaphnia dubia and Hyalella azteca in toxicity identification evaluations. Environ Toxicol Chem 25(4):973-984.
  • Wolf NM, Morisseau C, Jones PD, Hock B, Hammock BD. 2006. Development of a high-throughput screen for soluble epoxide hydrolase inhibition. Anal Biochem 355(1):71-80. PMID:16729954
  • Xu D, Li N, He Y, Timofeyev V, Lu L, Tsai H, Kim I, Tuteja D, Mateo RP, Singapuri A, Davis BB, Low R, Hammock BD, Chiamvimonvat N. 2006. Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors. Proc Natl Acad Sci U S A 103(49):18733-18738. PMID:17130447
  • Zhao B, Baston DS, Hammock BD, Denison MS. 2006. Interaction of diuron and related substituted phenylureas with the Ah receptor pathway. J Biochem Mol Toxicol 20(3):103-113. PMID:16788953

2005

  • Ahn K, Gee SJ, Kim HJ, Nichkova MJ, Hammock BD. 2005. Progress in the development of biosensors for environmental and human monitoring of agrochemicals. Proceedings of the American Chemical Society Pacifichem 966:138-154.
  • Aronov PA, Dettmer K, Christiansen JA, Cornel AJ, Hammock BD. 2005. Development of a HPLC/tandem-MS method for the analysis of the larvicides methoprene, hydroprene, and kinoprene at trace levels using Diels-Alder derivatization. J Agric Food Chem 53(9):3306-3312. doi:10.1021/jf0485842 PMID:15853364 PMCID:PMC1479544
  • Dorrance AM, Rupp N, Pollock DM, Newman JW, Hammock BD, Imig JD. 2005. An epoxide hydrolase inhibitor, 12-(3-Adamantan-1-yl-ureido)dodecanoic acid (AUDA) reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol 46(6):842-848.
  • Dosev D, Nichkova MJ, Liu M, Guo B, Liu G, Hammock BD, Kennedy IM. 2005. Application of luminescent Eu:Gd2O3 nanoparticles to the visualization of protein micropatterns. J Biomed Opt 10(6):1-7.
  • Dosev D, Nichkova MJ, Liu M, Guo B, Liu G, Xia Y, Hammock BD, Kennedy IM. 2005. Application of fluorescent Eu:Gd2O3 nanoparticles to the visualization of protein micropatterns. Chapter 5699 in: Imaging, Manipulation, and Analysis of Biomolecules and Cells: Fundamentals and Applications: III (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, San Jose, CA. pp.473-481.
  • Fang X, Hu S, Watanabe T, Weintraub NL, Snyder GD, Yao J, Liu Y, Shyy JY, Hammock BD, Spector AA. 2005. Activation of Peroxisome Proliferator-Activated Receptor by Substituted Urea-Derived Soluble Epoxide Hydrolase Inhibitors. J Pharmacol Exp Ther 314(1):260-270.
  • German JB, Hammock BD, Watkins SM. 2005. Metabolomics: building on a century of biochemistry to guide human health. Metabolomics 1(1):3-9. PMID:16680201
  • Hennebold JD, Mah K, Perez W, Vance JE, Stouffer RL, Morisseau C, Hammock BD, Adashi EY. 2005. Identification and characterization of an ovary-selective isoform of epoxide hydrolase. Biol Reprod 72(4):968-975. doi:10.1095/biolreprod.104.035899 PMID:15601917
  • Huang H, Fleming CD, Nishi K, Redinbo MR, Hammock BD. 2005. Stereoselective hydrolysis of pyrethroid-like fluorescent substrates by human and other mammalian liver carboxylesterases. Chem Res Toxicol 18(9):1371-1377. PMID:16167828
  • Huang H, Stok JE, Stoutamire DW, Gee SJ, Hammock BD. 2005. Development of optically pure pyrethroid-like fluorescent substrates for carboxylesterases. Chem Res Toxicol 18(3):516-527. doi:10.1021/tx049773h PMID:15777092
  • Imig JD, Zhao X, Zaharis CZ, Olearczyk JJ, Pollock DM, Newman JW, Kim I, Watanabe T, Hammock BD. 2005. An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension 46(4):975-981.
  • Inceoglu B, Lango J, Pessah IN, Hammock BD. 2005. Three structurally related, highly potent, peptides from the venom of Parabuthus transvaalicus possess divergent biological activity. Toxicon 45(6):727-733. PMID:15804521
  • Jones PD, Wolf NM, Morisseau C, Whetstone P, Hock B, Hammock BD. 2005. Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies. Anal Biochem 343(1):66-75. PMID:15963942
  • Jung O, Brandes RP, Kim I, Schweda F, Schmidt R, Hammock BD, Busse R, Fleming I. 2005. Soluble epoxide hydrolase is a main effector of angiotensin ll-induced hypertension. Hypertension 45(4):759-765.
  • Kang K, Jones PD, Huang H, Zhang R, Mostovich LA, Wheelock CE, Watanabe T, Gulyaeva LF, Hammock BD. 2005. Evaluation of a-cyano ethers as fluorescent substrates for assay of cytochrome P450 enyzme activity. Anal Biochem 344(2):183-192.
  • Kim I, Heirtzler FR, Morisseau C, Nishi K, Tsai H, Hammock BD. 2005. Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility. J Med Chem 48(10):3621-3629. doi:10.1021/jm0500929 PMID:15887969 PMCID:PMC1450255
  • Koivunen ME, Gee SJ, Park E, Lee K, Schenker MB, Hammock BD. 2005. Application of an enzyme-linked immunosorbent assay for the analysis of paraquat in human exposure samples. Arch Environ Contam Toxicol 48(2):184-190.
  • Liu Y, Zhang Y, Schmelzer KR, Lee T, Fang X, Zhu Y, Spector AA, Gill S, Morisseau C, Hammock BD, Shyy JY. 2005. The antiinflammatory effect of laminar flow: The role of PPAR, epoxyeicosatrienoic acids, and soluble epoxide hydrolase. Proc Natl Acad Sci U S A 102(46):16747-16752.
  • Mak SK, Shan G, Lee H, Watanabe T, Stoutamire DW, Gee SJ, Hammock BD. 2005. Development of a class selective immunoassay for the type II pyrethroid insecticides. Anal Chim Acta 534:109-120.
  • Morisseau C, Hammock BD. 2005. Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles. Annu Rev Pharmacol Toxicol 45:311-333.
  • Newman JW, Morisseau C, Hammock BD. 2005. Epoxide hydrolases: their roles and interactions with lipid metabolism. Prog Lipid Res 44(1):1-50. PMID:15748653
  • Nichkova MJ, Dosev D, Gee SJ, Hammock BD, Kennedy IM. 2005. Microarray of immunoassay for phenoxybenzoic acid using polymer encapsulated Eu:Gd2O3 nanoparticles as fluorescent labels. Anal Chem 77(21):6864-6873.
  • Nithipatikom K, Endsley MP, Isbell MA, Wheelock CE, Hammock BD, Campbell WB. 2005. A new class of inhibitors of 2-arachidonoylglycerol hydrolysis and invasion of prostate cancer cells. Biochem Biophys Res Commun 332(4):1028-1033. PMID:15919052
  • Schmelzer KR, Kubala L, Newman JW, Kim I, Eiserich JP, Hammock BD. 2005. Soluble epoxide hydrolase is a therapeutic target for acute inflammation. Proc Natl Acad Sci U S A 102(28):9772-9777. PMID:15994227
  • Sellers KW, Sun C, Diez-Freire C, Waki H, Morisseau C, Falck JR, Hammock BD, Paton JF, Raizada MK. 2005. Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat. FASEB J 19:626-628. PMID:15659536
  • Shearer GC, Newman JW, Hammock BD, Kaysen GA. 2005. Graded effects of proteinuria on HDL structure in nephrotic rats. J Am Soc Nephrol 16(5):1309-1319. PMID:15788471
  • Smith KR, Pinkerton KE, Watanabe T, Pedersen TL, Ma S, Hammock BD. 2005. Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor. Proc Natl Acad Sci U S A 102(6):2186-2191. PMID:15684051
  • Tran KL, Aronov PA, Tanaka H, Newman JW, Hammock BD, Morisseau C. 2005. Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase. Biochemistry 44(36):12179-12187. PMID:16142916
  • Wheelock CE, Eder KJ, Werner I, Huang H, Jones PD, Brammell BF, Elskus AA, Hammock BD. 2005. Individual variability in esterase activity and CYP1A levels in Chinook salmon (Oncorhynchus tshawytscha) exposed to esfenvalerate and chlorpyrifos. Aquat Toxicol 74(2):172-192.
  • Wheelock CE, Miller JL, Miller MJ, Phillips BM, Gee SJ, Tjeerdema RS, Hammock BD. 2005. Influence of container adsorption upon observed pyrethroid toxicity to Ceriodaphnia dubia and Hyalella azteca. Aquat Toxicol 74(1):47-52. PMID:15951033

2004

  • Ahn K, Watanabe T, Gee SJ, Hammock BD. 2004. Hapten and antibody production for a sensitive immunoassay determinining a human urinary metabolite of the pyrethroid insecticide permethrin. J Agric Food Chem 52(15):4583-4594.
  • Denison MS, Rogers WJ, Bohonowych JE, Zhao B, Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. 2004. Promiscuous ligand-dependent activation of the Ah receptor: chemicals in crude extracts from commercial and consumer products bind to and activate the Ah receptor and Ah receptor-dependent gene expression. Organohalogen Compounds 66:2966-2971.
  • Dey A, Williams RS, Pollock DM, Stepp DW, Newman JW, Hammock BD, Imig JD. 2004. Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obes Res 12(8):1278-1289. doi:10.1038/oby.2004.162 PMID:15340111
  • DuTeaux SB, Newman JW, Morisseau C, Fairbairn EA, Jelks K, Hammock BD, Miller MG. 2004. Epoxide hydrolases in the rat epididymis: possible roles in xenobiotic and endogenous fatty acid metabolism. J Toxicol Sci 78(2):187-195. PMID:14737000
  • Fang X, Weintraub NL, McCaw RB, Hu S, Harmon S, Rice JB, Hammock BD, Spector AA. 2004. Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels. Am J Physiol Cell Physiol 287:H2412-H2420. PMID:15284062
  • Gomez GA, Morisseau C, Hammock BD, Christianson DW. 2004. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry 43(16):4716-4723. doi:10.1021/bi036189j PMID:15096040
  • Kennedy IM, Koivunen ME, Gee SJ, Cummins CM, Perron R, Dosev D, Hammock BD. 2004. Nanoscale fluoro-immuno assays with lanthanide oxide nanoparticles. Chapter 5593 in: Nanosensing: Materials and Devices (Proceedings of SPIE). SPIE Society of Photo-Optical Instrumentation Engineering, Bellingham, WA. pp.329-339.
  • Kim I, Morisseau C, Watanabe T, Hammock BD. 2004. Design, synthesis, and biological activity of 1,3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility. J Med Chem 47(8):2110-2122. doi:10.1021/jm030514j PMID:15056008
  • Lee H, Shan G, Ahn K, Park E, Watanabe T, Gee SJ, Hammock BD. 2004. Development of an enzyme-linked Immunosorbent assay for the pyrethroid cypermethrin. J Agric Food Chem 52(2):1039-1043. PMID:14995094
  • Newman JW, Stok JE, Vidal JD, Corbin CJ, Huang Q, Hammock BD, Conley AJ. 2004. Cytochrome P450-dependent lipid metabolism in preovulatory follicles. Endocrinology 145(11):5097-5105. PMID:15308618
  • Nichkova MJ, Park E, Koivunen ME, Kamita SG, Gee SJ, Chuang J, Van Emon JM, Hammock BD. 2004. Immunochemical determination of dioxins in environmental and biological samples. Talanta 63:1213-1223.
  • Park E, Kim J, Gee SJ, Watanabe T, Ahn K, Hammock BD. 2004. Determination of pyrethroid residues in agricultural products by an enzyme-linked immunosorbent assay. J Agric Food Chem 52(18):5572-5576. PMID:15373394
  • Rufo C, Hammock BD, Gee SJ, Last JA, Gonzalez-Sapienza GG. 2004. Robust and sensitive monoclonal enzyme-linked immunosorbent assay for the herbicide molinate. J Agric Food Chem 52(2):182-187. PMID:14733492
  • Seubert JM, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman JW, Mao L, Rockman HA, Hammock BD, Murphy E, Zeldin DC. 2004. Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K+ Channels and p42/p44 MAPK Pathway. Circulation Research 95(5):506-514. PMID:15256482
  • Shan G, Huang H, Stoutamire DW, Gee SJ, Leng G, Hammock BD. 2004. A sensitive class specific immunoassay for the detection of pyrethroid metabolites in human urine. Chem Res Toxicol 17(2):218-225. PMID:14967009
  • Stok JE, Goloshchapov A, Song C, Wheelock CE, Derbel M, Morisseau C, Hammock BD. 2004. Investigation of the role of a second conserved serine in carboxylesterases via site-directed mutagenesis. Arch Biochem Biophys 430(2):247-255. PMID:15369824
  • Stok JE, Huang H, Jones PD, Wheelock CE, Morisseau C, Hammock BD. 2004. Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes. J Biol Chem 279(28):29863-29869. doi:10.1074/jbc.M403673200 PMID:15123619
  • Wheelock CE, Miller JL, Miller MJ, Gee SJ, Shan G, Hammock BD. 2004. Development of toxicity identification evaluation procedures for pyrethroid detection using esterase activity. Environ Toxicol Chem 23(11):2699-2708. PMID:15559286
  • Yu Z, Davis BB, Morisseau C, Hammock BD, Olson JL, Kroetz DL, Weiss RH. 2004. Vascular localization of soluble epoxide hydrolase in the human kidney. Am J Physiol Renal Physiol 286(4):F720-F726. PMID:14665429
  • Zhao X, Yamamoto T, Newman JW, Kim I, Watanabe T, Hammock BD, Stewart J, Imig JD. 2004. Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. J Am Soc Nephrol 15(5):1244-53. PMID:15100364

2003

  • Chen S, Yuen P, Collins SD, Smith R, Koivunen ME, Hammock BD. 2003. Time gated detection of europium nanoparticles in a microchannel-based environmental immunoassay. In: Proceedings of SPIE (The International Society for Optical Engineering).
  • Cho YA, Kim Y, Hammock BD, Lee YT, Lee H. 2003. Development of a microtiter plate ELISA and a dipstick ELISA for the determination of the organophosphorus insecticide fenthion. J Agric Food Chem 51(27):7854-7860. PMID:14690364
  • Denton DL, Wheelock CE, Murray SA, Deanovic LA, Hammock BD, Hinton DE. 2003. Joint acute toxicity of esfenvalerate and diazinon to fathead minnow (Pimephales promelas) larvae. Environ Toxicol Chem 22(2):336-341.
  • Feng J, Mack JS, Shan G, Hammock BD. 2003. C60 nanoparticle quenching used as a biological label. In: Proceedings of SPIE (The International Society for Optical Engineering). pp.156-163.
  • Feng J, Shan G, Hammock BD, Kennedy IM. 2003. Fluorescence quenching competitive immunoassay in micro droplets. Biosens Bioelectron 18(8):1055-1063. PMID:12782469
  • Feng J, Shan G, Maquieira A, Koivunen ME, Guo B, Hammock BD. 2003. Functionalized Europium Oxide Nanoparticles Used as a Fluorescent Label in an Immunoassay for Atrazine. Anal Chem 75(19):5282-5286.
  • Inceoglu B, Lango J, Jing J, Chen L, Doymaz F, Pessah IN, Hammock BD. 2003. One scorpion, two venoms: Prevenom of Parabuthus transvaalicus acts as an alternative type of venom with distinct mechanism of action. Proc Natl Acad Sci U S A 100(3):922-927. PMID:12552107
  • Kim Y, Cho YA, Lee H, Lee YT, Gee SJ, Hammock BD. 2003. Synthesis of haptens for immunoassay of organophosphorus pesticides and effect of heterology in hapten spacer arm length of immunoassay sensitivity. Anal Chim Acta 475(1-2):85-96.
  • Koivunen ME, Morisseau C, Newman JW, Horwath WR, Hammock BD. 2003. Purification and characterization of a methylene urea-hydrolyzing enzyme from Rhizobium radiobacter (Agrobacterium tumefaciens). Soil Biol Biochem 35(11):1433-1442.
  • Lee H, Watanabe T, Gee SJ, Hammock BD. 2003. Application of an Enzyme-Linked Immunosorbent Assay (ELISA) to Determine Deltamethrin Residues in Milk. Bull Environ Contam Toxicol 71(1):14-20. PMID:12945836
  • Lee JK, Ahn K, Stoutamire DW, Gee SJ, Hammock BD. 2003. Development of an Enzyme-Linked Immunosorbent Assay for the Detection of the Organophosphorus Insecticide Acephate. J Agric Food Chem 51(13):3695-3703. PMID:12797729
  • McElroy NR, Jurs PC, Morisseau C, Hammock BD. 2003. QSAR and classification of murine and human soluble epoxide hydrolase inhibition by urea-like compounds. J Med Chem 46(6):1066-1080. PMID:12620084
  • Morisseau C, Hammock BD. 2003. Measurements of soluble epoxide hydrolase (sEH) activity. Chapter 4 in: Current Protocals in Toxicology. John Wiley & Sons, NY. pp.1-4.
  • Newman JW, Morisseau C, Harris TR, Hammock BD. 2003. The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity. Proc Natl Acad Sci U S A 100(4):1558-1563. PMID:12574510
  • Nichkova MJ, Feng J, Sanchez-Baeza F, Marco M, Hammock BD, Kennedy IM. 2003. Competitive quenching fluorescence immunoassy for chlorophenols based on laser-induced fluorescence detection in microdroplets. Anal Chem 75(1):83-90.
  • Przybyla-Zawislak BD, Srivastava PK, Vazquez-Matias J, Mohrenweiser HW, Maxwell JE, Hammock BD, Bradbury JA, Enayetallah AE, Zeldin DC, Grant DF. 2003. Polymorphisms in human soluble epoxide hydrolase. Mol Pharmacol 64(2):482-490. PMID:12869654
  • Szekacs A, Le HM, Szurdoki F, Hammock BD. 2003. Optimization and validation of an enzyme immunoassay for the insect growth regulator fenoxycarb. Anal Chim Acta 487(1):15-29.
  • Taniai K, Inceoglu AB, Yukuhiro K, Hammock BD. 2003. Characterization and cDNA cloning of a clofibrate-inducible microsomal epoxide hydrolase in Drosophila melanogaster. FEBS J 270(23):4696-4705. PMID:14622257
  • Viswanathan S, Hammock BD, Newman JW, Meerarani P, Toborek M, Hennig B. 2003. Involvement of CYP 2C9 in Mediating the Proinflammatory Effects of Linoleic Acid in Vascular Endothelial Cells. J Am Coll Nutr 22(6):502-510.
  • Watanabe T, Morisseau C, Newman JW, Hammock BD. 2003. In vitro metabolism of the mammalian soluble epoxide hydrolase inhibitor, 1-cyclohexyl-3-dodecy1-urea. Drug Metab Dispos 31(7):846-853.
  • Wheelock CE, Nakagawa Y, Akamatsu M, Hammock BD. 2003. Use of classical and 3-D QSAR to examine the hydration state of juvenile hormone esterase inhibitors. Bioorg Med Chem 11(23):5101-5116.
  • Wheelock CE, Wheelock AM, Zhang RH, Stok JE, Morisseau C, Le Valley SE, Green CE, Hammock BD. 2003. Evaluation of alpha-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes. Anal Biochem 315(2):208-222. PMID:12689831
  • Zhang RH, Kang K, Shan G, Hammock BD. 2003. Design, synthesis and evaluation of novel P450 fluorescent probes bearing -cyanoether. Tetrahedron Lett 44(23):4331-4334.

2002

  • Cho YA, Lee H, Park EY, Lee YT, Hammock BD, Ahn K, Lee JK. 2002. Development of an ELISA for the organophosphorus insecticide chlorpyrifos. Bulletin of the Korean Chemical Society 23(3):481-487.
  • Davis BB, Thompson DA, Howard LL, Morisseau C, Hammock BD, Weiss RH. 2002. Inhibitors of soluble epoxide hydrolase attenuate vascular smooth muscle cell proliferation. Proc Natl Acad Sci U S A 99(4):2222-2227. PMID:11842228
  • Dedos SG, Szurdoki F, Szekacs A, Shiotsuki T, Hammock BD, Shimada J, Fugo H. 2002. Fenoxycarb levels and their effects on general and juvenile hormone esterase activity in the hemolymph of the silkworm, Bombyx mori. Pesticide Biochemistry and Physiology 73(3):174-187.
  • Denison MS, Nagy SR, Ziccardi MH, Clark GC, Chu MD, Brown DJ, Shan G, Sugawara Y, Gee SJ, Sanborn JR, Hammock BD. 2002. Bioanalytical approaches for the detection of dioxin and related halogenated aromatic hydrocarbons. In: Biomarkers of Environmentally Associated Disease: Technologies, Concepts, and Perspectives. CRC Press Company, Boca Raton, FL. pp.483-494.
  • Fang X, Weintraub NL, Oltman CL, Stoll LL, Kaduce TL, Harmon S, Dellsperger KC, Morisseau C, Hammock BD, Spector AA. 2002. Human coronary endothelial cells convert 14, 15-EET to a biologically active chain-shortened epoxide. Am J Physiol Heart Circ Physiol 283(6):H2306-H2314.
  • Feng J, Shan G, Hammock BD, Kennedy IM. 2002. Fluorescence quenching competitive fluoroimmunoassay in micro droplets. In: Methods for Ultrasensitive Detection II, Proceedings of the International Society for Optical Engineering. SPIE, Bellingham, WA. pp.118-127.
  • Fornage M, Hinojos CA, Nurowska BW, Boerwinkle E, Hammock BD, Morisseau C, Doris PA. 2002. Polymorphism in soluble epoxide hydrolase and blood pressure in spontaneously hypertensive rats. Hypertension 40(4):485-490. PMID:12364351
  • Harcourt RL, Horne I, Sutherland TD, Hammock BD, Russell RJ, Oakeshott JG. 2002. Development of a simple and sensitive fluorimetric method for isolation or coumaphos-hydrolysing bacteria. Lett Appl Microbiol 34(4):263-268.
  • Hennig B, Hammock BD, Slim RM, Toborek M, Viswanathan S, Robertson LW. 2002. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. Int J Hyg Environ Health 205(1-2):95-102.
  • Imig JD, Zhao X, Capdevila JH, Morisseau C, Hammock BD. 2002. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension. Hypertension 39(2):690-694. PMID:11882632
  • Inceoglu B, Hayashida Y, Lango J, Ishida AT, Hammock BD. 2002. A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus. FEBS J 269(22):5369-5376.
  • Kim K, Kim Y, Lee YT, Hammock BD, Lee H. 2002. Development of an enzyme-linked immunosorbent assay for the organophosphorus insecticide bromophos-ethyl. J Agric Food Chem 50(23):6675-6682. PMID:12405760
  • Lee H, Shan G, Watanabe T, Stoutamire DW, Gee SJ, Hammock BD. 2002. Enzyme-linked immunosorbent assay for the pyrethroid deltamethrin. J Agric Food Chem 50(20):5526-5532. PMID:12236674
  • Leppert VJ, Harvey AS, McCool GD, Quinlan FT, Feng J, Shan G, Stroeve P, Risbud SH, Hammock BD, Kennedy IM. 2002. Long-wavelength emitting nanocrystals for bioassay applications. In: Nanoscale Optics and Applications. Proceedings of SPIE, pp.110-121.
  • Morisseau C, Goodrow MH, Newman JW, Wheelock CE, Dowdy DL, Hammock BD. 2002. Structural refinement of inhibitors of urea based soluble epoxide hydrolases. Biochem Pharmacol 63(9):1599-1608.
  • Morisseau C, Hammock BD. 2002. Epoxide Hydrolases. In: Wiley Encyclopedia of Molecular Medicine. Medicine John Wiley & Sons Inc., New York, NY. pp.1194-1197.
  • Nagy SR, Sanborn JR, Hammock BD, Denison MS. 2002. Development of a green fluorescent protein based cell bioassay for the rapid and inexpensive detection and characterization of AhR agonists. J Toxicol Sci 65(2):200-210.
  • Newman JW, Watanabe T, Hammock BD. 2002. The simultaneous quantification of cytochrome P450 dependent linoleate and arachidonate metabolites in urine by HPLC-MS/MS. J Lipid Res 43(9):1563-1578. PMID:12235189
  • Park WC, Cho YA, Kim Y, Hammock BD, Lee YT, Lee H. 2002. Development of an enzyme-linked immunosorbent assay for the organophosphorus insecticide bromophos. Bulletin of the Korean Chemical Society 23(10):1399-1403.
  • Severson T, Goodrow MH, Morisseau C, Dowdy DL, Hammock BD. 2002. Urea and amide-based inhibitors of the juvenile hormone epoxide hydrolase of the tobacco hornworm(Manduca sexta: Sphingidae). Insect Biochem Mol Biol 32:1741-1756.
  • Shelver WL, Shan G, Gee SJ, Stanker LH, Hammock BD. 2002. Comparison of immunoaffinity column recovery patterns of polychlorinated dibenzo-p-dioxins/polychlorinated dibenzofurans on columns generated with different monoclonal antibody clones and polyclonal antibodies. Anal Chim Acta 457:199-209.
  • Sugawara Y, Saito K, Ogawa M, Kobayashi S, Shan G, Sanborn JR, Hammock BD, Nakazawa H, Matsuki Y. 2002. Development of dioxin toxicity evaluation method in human milk by enzyme-linked immunosorbent assay--assay validation for human milk. Chemosphere 46(9-10):1471-1476.
  • Szurdoki F, Szekacs A, Le HM, Hammock BD. 2002. Synthesis of haptens and protein conjugates for the development of immunoassays for the insect growth regulator fenoxycarb. J Agric Food Chem 50(1):29-40. PMID:11754538
  • Viswanathan S, Hammock BD, Meerarani P, Toborek M, Hennig B. 2002. Mechanisms of linoleic acid-induced endothelial activation: possible involvement of epoxide metabolites in mediating the inflammatory response. FASEB J 16:A157.
  • Wheelock CE, Colvin ME, Uemura I, Olmstead MM, Sanborn JR, Nakagawa Y, Jones AD, Hammock BD. 2002. Use of ab initio calculations to predict the biological potency of carboxylesterase inhibitors. J Med Chem 45(25):5576-5593. PMID:12459025
  • Zurek G, Gee SJ, Hammock BD. 2002. Development of an enzyme immunoassay for linoleic acid diols in urine. Anal Chim Acta 466(2):247-256.

2001

  • Buchholz BA, Vogel JS, Gilman DS, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. 2001. Determining an occupational dermal exposure biomarker for atrazine through measurement of metabolites in human urine by HPLC-accelerator mass spectrometry. In: Toxicology of Skin. Taylor & Francis, Philadelphia, PA. pp.145-157.
  • Fang X, Kaduce TL, Weintraub NL, Harmon S, Teesch LM, Morisseau C, Thompson DA, Hammock BD, Spector AA. 2001. Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells: Implications for the vascular effects of soluble epoxide hydrolase inhibition. J Biol Chem 276(18):14867-14874.
  • Hennig B, Slim RM, Toborek M, Hammock BD, Robertson LW. 2001. Cardiovascular disease: endothelial cells as a target for PCB toxicity. In: PCBs: Recent Advances in Environmental Toxicology and Health Effects. University Kentucky Press, Lexington, KY. pp.211-220.
  • Hennig B, Viswanathan S, Toborek M, Hammock BD. 2001. Mechanisms of fatty-acid mediated endothelial cell activation. J Am Coll Nutr 20:574.
  • Huang Q, Deveraux QL, Maeda S, Stennicke HR, Hammock BD, Reed JC. 2001. Cloning and characterization of an inhibitor of apoptosis protein (IAP) from Bombyx mori. Biochim Biophys Acta 1499(3):191-198. PMID:11341966
  • Inceoglu B, Lango J, Wu J, Hawkins P, Southern J, Hammock BD. 2001. Isolation and characterization of a novel type of neurotoxic peptide from the venom of the South African scorpion Parabuthus transvaalicus (Buthidae). FEBS J 268(20):5407-5413. PMID:11606203
  • Lee JK, Ahn K, Park OS, Kang SY, Hammock BD. 2001. Development of an ELISA for the detection of the residues of the insecticide imidacloprid in agricultural and environmental samples. J Agric Food Chem 49(5):2159-2167. PMID:11368571
  • Matveeva EG, Gribkova EV, Sanborn JR, Gee SJ, Hammock BD, Savitsky AP. 2001. Development of a homogeneous phosphorescent immunoassay for the detection of polychlorinated dibenzo-p-dioxins. Anal Lett 34(13):2311-2320.
  • Matveeva EG, Shan G, Kennedy IM, Gee SJ, Hammock BD. 2001. Homogeneous fluoroimmunoassay of a pyrethroid metabolite in urine. Anal Chim Acta 444:103-117.
  • Miyashita M, Presley JM, Buchholz BA, Lam KS, Lee YM, Vogel JS, Hammock BD. 2001. Attomole level protein sequencing by Edman degradation coupled with accelerator mass spectrometry. Proc Natl Acad Sci U S A 98(8):4403-4408. PMID:11287636
  • Morisseau C, Newman JW, Dowdy DL, Goodrow MH, Hammock BD. 2001. Inhibition of microsomal epoxide hydrolases by ureas, amides and amines. Chem Res Toxicol 14(4):409-415.
  • Newman JW, Denton DL, Morisseau C, Koger CS, Wheelock CE, Hinton DE, Hammock BD. 2001. Evaluation of fish models of soluble epoxide hydrolase inhibition. Environ Health Perspect 109(1):61-66. PMID:11171526 PMCID:PMC1242052
  • Newman JW, Hammock BD. 2001. Optimized thiol derivatizing reagent for the mass spectral analysis of disubstituted epoxy fatty acids. J Chromatogr A 925(1-2):223-240. PMID:11519808
  • Shan G, Hammock BD. 2001. Development of sensitive esterase assays based on alpha-cyano-containing esters. Anal Biochem 299(1):54-62. PMID:11726184
  • Shan G, Leeman WR, Gee SJ, Sanborn JR, Jones AD, Chang DP, Hammock BD. 2001. Highly sensitive dioxin immunoassay and its application to soil and biota samples. Anal Chim Acta 444:169-178.
  • Sisemore MF, Zheng J, Yang JC, Thompson DA, Plopper CG, Cortopassi GA, Hammock BD. 2001. Cellular characterization of leukotoxin diol-induced mitochondrial dysfunction. Arch Biochem Biophys 392(1):32-37. PMID:11469791
  • Slim RM, Hammock BD, Toborek M, Robertson LW. 2001. The role of methyl linoleic acid epoxide and diol metabolites in the synergistic toxicity of linoleic acid and PCBs to vascular endothelial cells. J Toxicol Sci 60:13.
  • Slim RM, Hammock BD, Toborek M, Robertson LW, Newman JW, Morisseau C, Watkins BA, Viswanathan S, Hennig B. 2001. The role of methyl-linoleic acid epoxide and diol metabolites in the amplified toxicity of linoleic acid and polychlorinated biphenyls to vascular endothelial cells. Toxicol Appl Pharmacol 171(3):184-193. PMID:11243918
  • Staimer N, Gee SJ, Hammock BD. 2001. Development of a class-selective enzyme immunoassay for urinary phenolic glucuronides. Anal Chim Acta 444:27-36.
  • Staimer N, Gee SJ, Hammock BD. 2001. Development of a sensitive enzyme immunoassay for the detection of phenyl-b-D-thioglucuronide in human urine. Fresenius J Anal Chem 369(3-4):273-279.
  • Viswanathan S, Narayan P, Hammock BD, Meerarani P, Toborek M, Hennig B. 2001. Linoleic acid-derived epoxides alter calcium and nitric oxide metabolism in endothelial cells. FASEB J 15:A190.
  • Watanabe T, Hammock BD. 2001. Rapid determination of soluble epoxide hydrolase inhibitors in rat hepatic microsomes by high performance liquid chromatography with electrospray tandem mass spectrometry. Anal Biochem 299(2):227-234.
  • Watanabe T, Shan G, Stoutamire DW, Gee SJ, Hammock BD. 2001. Development of a class-specific immunoassay for the type I pyrethroid insecticides. Anal Chim Acta 444:119-129.
  • Watkins SM, Hammock BD, Newman JW, German JB. 2001. Individual metabolism should guide agriculture toward foods for improved health and nutrition. Am J Clin Nutr 74(3):283-286. PMID:11522549
  • Wheelock CE, Severson T, Hammock BD. 2001. Synthesis of new carboxylesterase inhibitors and evaluation of potency and water solubility. Chem Res Toxicol 14(12):1563-1572. PMID:11743738
  • Wudayagiri R, Inceoglu B, Herrmann R, Derbel M, Choudary P, Hammock BD. 2001. Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus. BMC Bioinformatics 2:16. PMID:11782289
  • Zheng J, Plopper CG, Lakritz J, Storms DH, Hammock BD. 2001. Leukotoxin-diol - A putative toxic mediator involved in acute respiratory distress syndrome. Am J Respir Cell Mol Biol 25(4):434-438. PMID:11694448

2000

  • Argiriadi MA, Morisseau C, Goodrow MH, Dowdy DL, Hammock BD, Christianson DW. 2000. Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation. J Biol Chem 275(20):15265-15270. PMID:10747889
  • Draper AJ, Hammock BD. 2000. Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase. Arch Biochem Biophys 376(1):199-205. PMID:10729206
  • Fanucchi MV, Buckpitt AR, Murphy M, Storms DH, Hammock BD, Plopper CG. 2000. Development of phase II xenobiotic metabolizing enzymes in differentiating murine Clara cells. Toxicol Appl Pharmacol 168(3):253-267. PMID:11042098
  • Greene JF, Newman JW, Williamson K, Hammock BD. 2000. Toxicity of epoxy fatty acids and related compounds to cells expressing human soluble epoxide hydrolase. Chem Res Toxicol 13(4):217-226. PMID:10775319
  • Greene JF, Williamson K, Newman JW, Morisseau C, Hammock BD. 2000. Metabolism of monoepoxides of methyl linoleate: bioactivation and detoxification. Arch Biochem Biophys 376(2):420-432. PMID:10775430
  • Greene JF, Zheng J, Grant DF, Hammock BD. 2000. Cytotoxicity of 1,2-epoxynaphthalene is correlated with protein binding and in situ glutathione depletion in cytochrome P4501A1 expressing Sf-21 cells. J Toxicol Sci 53(2):352-360. PMID:10696783
  • Huang Q, Deveraux QL, Maeda S, Salvesen GS, Stennicke HR, Hammock BD, Reed JC. 2000. Evolutionary conservation of apoptosis mechanisms: lepidopteran and baculoviral inhibitor of apoptosis proteins are inhibitors of mammalian caspase-9. Proc Natl Acad Sci U S A 97(4):1427-1432. PMID:10677478 PMCID:PMC26450
  • Kido H, Maquieira A, Hammock BD. 2000. Disc-based immunoassay microarrays. Anal Chim Acta 411(1-2):1-11.
  • Lakritz J, Winder BS, Noorouz-Zadeh J, Huang TL, Buckpitt AR, Hammock BD, Plopper CG. 2000. Hepatic and pulmonary enzyme activities in horses. American Journal of Veterinary Research 61(2):152-157. PMID:10685686
  • Lohse C, Jaeger LL, Staimer N, Sanborn JR, Jones AD, Lango J, Gee SJ, Hammock BD. 2000. Development of a class selective enzyme-linked immunosorbent assay for mercapturic acids in human urine. J Agric Food Chem 48(12):5913-5923. PMID:11312767
  • Morisseau C, Beetham JK, Pinot F, Debernard S, Newman JW, Hammock BD. 2000. Cress and potato soluble epoxide hydrolases: Purification, biochemical characterization, and comparison to mammalian enzymes. Arch Biochem Biophys 378(2):321-332. PMID:10860549
  • Nakagawa Y, Wheelock CE, Morisseau C, Goodrow MH, Hammock BG, Hammock BD. 2000. 3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues. Bioorg Med Chem 8(11):2663-2673. PMID:11092551
  • Shan G, Huang W, Gee SJ, Buchholz BA, Vogel JS, Hammock BD. 2000. Isotope-labeled immunoassays without radiation waste. Proc Natl Acad Sci U S A 97(6):2445-2449. PMID:10706612
  • Shan G, Leeman WR, Stoutamire DW, Gee SJ, Chang DP, Hammock BD. 2000. Enzyme-linked immunosorbent assay for the pyrethroid permethrin. J Agric Food Chem 48(9):4032-4040. PMID:10995309
  • Shan G, Sanborn JR, Gilman DS, Nagy SR, Gee SJ, Stoutamire DW, Mercer RS, Jones AD, Stanker LH, Denison MS, Hammock BD. 2000. Surrogates for dioxin analyses: analytical, ELISA and toxicological aspects. Organohalogen Compounds 45:188-191.
  • Williamson K, Morisseau C, Maxwell JE, Hammock BD. 2000. Regio- and enantioselective hydrolysis of phenyloxiranes catalyzed by soluble epoxide hydrolase. Tetrahedron: Asymmetry 11:4451-4462.
  • Yamada T, Morisseau C, Maxwell JE, Argiriadi MA, Christianson DW, Hammock BD. 2000. Biochemical evidence for the involvement of tyrosine in epoxide activation during the catalytic cycle of epoxide hydrolase. J Biol Chem 275(30):23082-23088. PMID:10806198
  • Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC, Kroetz DL. 2000. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circulation Research 87(11):992-998. PMID:11090543

1999

  • Argiriadi MA, Morisseau C, Hammock BD, Christianson DW. 1999. Detoxification of environmental mutagens and carcinogens: Structure, mechanism, and evolution of liver epoxide hydrolase. Proc Natl Acad Sci U S A 96:10637-10642. PMID:10485878
  • Buchholz BA, Fultz E, Haack KW, Vogel JS, Gilman DS, Gee SJ, Hammock BD, Hui X, Wester RC, Maibach HI. 1999. HPLC-accelerator MS measurement of atrazine metabolites in human urine after dermal exposure. Anal Chem 71(16):3519-3525. PMID:10464479
  • Draper AJ, Hammock BD. 1999. Inhibition of soluble and microsomal epoxide hydrolase by zinc and other metals. J Toxicol Sci 52:26-32. PMID:10568695
  • Draper AJ, Hammock BD. 1999. Soluble epoxide hydrolase in rat inflammatory cells is indistinguishable from soluble epoxide hydrolase in rat liver. J Toxicol Sci 50:30-35. PMID:10445750
  • Kido H, Szurdoki F, Gustin MS, Hammock BD. 1999. Chelate sensor method for mercury. In: Metals and Genetics. Kluwer Academic/Plenum Press, NY. pp.235-259.
  • Morisseau C, Derbel M, Lane TR, Stoutamire DW, Hammock BD. 1999. Differential induction of hepatic drug-metabolizing enzymes by fenvaleric acid in male rats. J Toxicol Sci 52(2):148-153. PMID:10630566
  • Morisseau C, Goodrow MH, Dowdy DL, Zheng J, Greene JF, Sanborn JR, Hammock BD. 1999. Potent urea and carbamate inhibitors of soluble epoxide hydrolases. Proc Natl Acad Sci U S A 96(16):8849-8854. PMID:10430859
  • Morisseau C, Ward BL, Gilchrist DG, Hammock BD. 1999. Multiple epoxide hydrolases in Alternaria alternata f. sp. lycopersici and their relationship to medium composition and host-specific toxin production. Appl Environ Microbiol 65(6):2388-2395.
  • Mullen RT, Trelease RN, Duerk H, Arand M, Hammock BD, Oesch F, Grant DF. 1999. Differential subcellular localization of endogenous and transfected soluble epoxide hydrolase in mammalian cells: evidence for isozyme variants. FEBS Lett 445(2-3):301-305. PMID:10094477
  • Shan G, Stoutamire DW, Gee SJ, Wengatz I, Hammock BD. 1999. Development of an immunoassay for the pyrethroid insecticide esfenvalerate. J Agric Food Chem 47(5):2145-2155. PMID:10552511
  • Shan G, Wengatz I, Stoutamire DW, Gee SJ, Hammock BD. 1999. An enzyme-linked immunosorbent assay for the detection of esfenvalerate metabolites in human urine. Chem Res Toxicol 12(11):1033-1041. PMID:10563828
  • Thomas BA, Church WB, Lane TR, Hammock BD. 1999. Homology model of juvenile hormone esterase from the crop pest, Heliothis virescens. Proteins: Structure, Function, and Genetics 34(2):184-196. PMID:10022354
  • Yazynina EV, Zherdev AV, Dzantiev BB, Izumrudov VA, Gee SJ, Hammock BD. 1999. Immunoassay techniques for detection of the herbicide simazine based on use of oppositely charged water-soluble polyelectrolytes. Anal Chem 71(16):3538-3543. PMID:10464482
  • Yazynina EV, Zherdev AV, Dzantiev BB, Izumrudov VA, Gee SJ, Hammock BD. 1999. Microplate immunoassay technique using polyelectrolyte carriers: kinetic studies and application to detection of the herbicide atrazine. Anal Chim Acta 399(1-2):151-160.

1998

  • Gilman DS, Gee SJ, Hammock BD, Vogel JS, Haack KW, Buchholz BA, Freeman SP, Wester RC, Hui X, Maibach HI. 1998. Analytical performance of accelerator mass spectrometry and liquid scintillation counting for detection of 14C-labeled atrazine metabolites in human urine. Anal Chem 70(16):3463-3469.
  • Goodrow MH, Hammock BD. 1998. Hapten design for compound-selective antibodies: ELISA's for environmentally deleterious small molecules. Anal Chim Acta 376(1):83-91.
  • Harris AS, Wengatz I, Wortberg M, Kreissig SB, Gee SJ, Hammock BD. 1998. Development and application of immunoassays for biological and environmental monitoring. In: Effects of Multiple Impacts on Ecosystems. Lewis Publishers, Chelsea, MI. pp.135-153.
  • Jaeger LL, Jones AD, Hammock BD. 1998. Development of an enzyme-linked immunosorbent assay for atrazine mercapturic acid in human urine. Chem Res Toxicol 11(4):342-352. doi:10.1021/tx9701844 PMID:9548805
  • Marco M, Gee SJ, Hammock BD. 1998. Determination of 1-naphthol in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C.9.1-2C.9.11.
  • Marco M, Gee SJ, Hammock BD. 1998. Determination of carbaryl in well water samples by ELISA. In: Current Protocols in Field Analytical Chemistry. (V. Lopez-Avila, ed.) John Wiley & Sons, New York, NY. pp.2C8.1-2C8.15.
  • Mitchell AE, Zheng J, Hammock BD, Lo Bello M, Jones AD. 1998. Structural and functional consequences of haloenol lactone inactivation of murine and human glutathione S-transferase. Biochemistry 37(19):6752-6759. PMID:9578559
  • Reimer GJ, Gee SJ, Hammock BD. 1998. Comparison of a time-resolved fluorescence immunoassay and an enzyme-linked immunosorbent assay for the analysis of atrazine in water. J Agric Food Chem 46(8):3353-3358.
  • Sanborn JR, Gee SJ, Gilman DS, Sugawara Y, Jones AD, Rogers JM, Szurdoki F, Stanker LH, Stoutamire DW, Hammock BD. 1998. Hapten synthesis and antibody development for polychlorinated dibenzo-p-dioxin immunoassays. J Agric Food Chem 46:2407-2416.
  • Sugawara Y, Gee SJ, Sanborn JR, Gilman DS, Hammock BD. 1998. Development of a highly sensitive enzyme-linked immunosorbent assay based on polyclonal antibodies for the detection of polychlorinated dibenzo-p-dioxins. Anal Chem 70(6):1092-1099. PMID:9530001
  • Wengatz I, Stoutamire DW, Gee SJ, Hammock BD. 1998. Development of an enzymelinked immunosorbent assay for the detection of the pyrethroid insecticide fenpropathrin. J Agric Food Chem 46(6):2211-2221.

1997

  • Jones G, Wortberg M, Rocke DM, Hammock BD. 1997. Immunoassay of cross-reacting analytes. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.331-342.
  • Kido H, Goodrow MH, Griffeth V, Lucas AD, Gee SJ, Hammock BD. 1997. Development of an enzyme-linked immunosorbent assay for the detection of hydroxytriazines. J Agric Food Chem 45(2):414-424.
  • Moghaddam MF, Grant DF, Cheek JM, Greene JF, Williamson K, Hammock BD. 1997. Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase. Nat Med 3(5):562-566. PMID:9142128
  • Schutz S, Wengatz I, Goodrow MH, Gee SJ, Hummel HE, Hammock BD. 1997. Development of an enzyme-linked-immunosorbent assay for azadirachtins. J Agric Food Chem 45(6):2363-2368.
  • Swamy AR, Danesvar MI, Evans, III L, Strekowski L, Narayanan N, Szurdoki F, Wengatz I, Hammock BD, Patonay G. 1997. Near-infrared fluorescent immunoassays: A novel approach to environmental analysis. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.141-161.
  • Szurdoki F, Kido H, Hammock BD. 1997. Rapid mercury assays. In: Immunochemical Technology for Environmental Applications (ACS Symposium Series No. 657). American Chemical Society, Washington, DC. pp.38-48.
  • Zheng J, Cho M, Jones AD, Hammock BD. 1997. Evidence of quinone metabolites of naphthalene covalently bound to sulfur nucleophiles of proteins of murine clara cells after exposure to naphthalene. Chem Res Toxicol 10(9):1008-1014. PMID:9305583

1996

  • Grant DF, Greene JF, Pinot F, Borhan B, Moghaddam MF, Hammock BD, McCutchen B, Ohkawa H, Luo G, Guenthner TM. 1996. Development of an in situ toxicity assay system using recombinant baculoviruses. Biochem Pharmacol 51(4):503-515. PMID:8619897
  • Jones G, Wortberg M, Hammock BD, Rocke DM. 1996. A procedure for the immunoanalysis of samples containing one or more members of a group of cross-reacting analytes. Anal Chim Acta 336(1-3):175-183.
  • Jones G, Wortberg M, Kreissig SB, Hammock BD, Rocke DM. 1996. Application of the bootstrap to calibration experiments. Anal Chem 68(5):763-770. PMID:8779441
  • Linde CD, Gee SJ, Goh KS, Hsu JC, Hammock BD, Barry TA, Weaver DJ. 1996. Regulatory application of ELISA: Compliance monitoring of bromacil in soil. Bull Environ Contam Toxicol 57(2):264-269.
  • Szurdoki F, Jaeger LL, Harris AS, Kido H, Wengatz I, Goodrow MH, Szekacs A, Wortberg M, Zheng J, Stoutamire DW, Sanborn JR, Gilman DS, Jones AD, Gee SJ, Choudary P, Hammock BD. 1996. Rapid assays for environmental and biological monitoring. Journal of Environmental Science and Health 31(3):451-458. PMID:8642182
  • Wengatz I, Harris AS, Gilman DS, Wortberg M, Kido H, Szurdoki F, Goodrow MH, Jaeger LL, Stoutamire DW, Sanborn JR, Gee SJ, Hammock BD. 1996. Recent developments in immunoassays and related methods for the detection of xenobiotics. In: Environmental Immunochemical Methods, Perspectives and Applications. ACS Symposium Series No. 646, American Chemical Society, Washington, DC. pp.110-126.
  • Wortberg M, Goodrow MH, Gee SJ, Hammock BD. 1996. Immunoassay for simazine and atrazine with low cross-reactivity for propazine. J Agric Food Chem 44(8):2210-2219.
  • Wortberg M, Jones G, Kreissig SB, Rocke DM, Gee SJ, Hammock BD. 1996. An approach to the construction of an immunoarray for differentiating and quantitating cross reacting analytes. Anal Chim Acta 319(3):291-303.
  • Zheng J, Hammock BD. 1996. Development of polyclonal antibodies for detection of protein modification by 1,2-naphthoquinone. Chem Res Toxicol 9(5):904-909. PMID:8828928
  • Zheng J, Mitchell AE, Jones AD, Hammock BD. 1996. Haloenol lactone is a new isozyme-selective and active site-directed inactivator of glutathione S-transferase. J Biol Chem 271(34):20421-20425. PMID:8702779

1995

  • Borhan B, Jones AD, Pinot F, Grant DF, Kurth M, Hammock BD. 1995. Mechanism of soluble epoxide hydrolase. Formation of An a-hydroxy ester-enzyme intermediate through Asp-333. J Biol Chem 270(45):26923-26930.
  • Choudary P, Lee HA, Hammock BD, Morgan MR. 1995. Recombinant antibodies: New tools for immunoassays. Chapter 13 in: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.171-185.
  • Gee SJ, Hammock BD, Skerritt JH. 1995. Diagnostics for plant agrochemicals--a meeting of chemistry and immunoassay. In: New Diagnostics in Crop Sciences. CAB International, Oxon, United Kingdom. pp.243-276.
  • Gee SJ, Lucas AD, Hammock BD. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Proceedings of the NATO (North Atlantic Treaty Organisation) Workshop on Methods of Pesticide Exposure Assessment. Ottawa, Canada.
  • Gee SJ, Lucas AD, Hammock BD. 1995. Using immunochemical methods to analyze for biomarkers of exposure. In: Methods of Pesticide Exposure Assessment. Plenum Press, NY. pp.143-155.
  • Goodrow MH, Sanborn JR, Stoutamire DW, Gee SJ, Hammock BD. 1995. Strategies for immunoassay hapten design. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.119-139.
  • Hammock BD, Gee SJ. 1995. Impact of emerging technologies on immunochemical methods for environmental analysis. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.1-19.
  • Harris AS, Lucas AD, Kramer PM, Marco M, Gee SJ, Hammock BD. 1995. Use of immunoassay for the detection of urinary biomarkers of exposure. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.217-235.
  • Jones G, Wortberg M, Kreissig SB, Hammock BD, Rocke DM. 1995. Sources of experimental variation in calibration curves for enzyme-linked immunosorbent assay. Anal Chim Acta 313:197-207.
  • Kreissig SB, Ward VK, Hammock BD, Choudary P. 1995. Nucleotide sequence of the variable region of the heavy and light chains of a monoclonal lgG antibody reactive to herbicides, terbutryn and prometryn. DNA Seq 6:51-54.
  • Kreissig SB, Ward VK, Hammock BD, Choudary P. 1995. Sequence analysis of individual chains of antibodies to triazine herbicides. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.31-49.
  • Lucas AD, Gee SJ, Hammock BD, Seiber JN. 1995. Integration of immunochemical methods with other analytical techniques for pesticide residue determination. J AOAC Int 78(3):585-591.
  • Lucas AD, Goodrow MH, Seiber JN, Hammock BD. 1995. Development of an ELISA for the N-dealkylated s-triazines: Application to environmental and biological samples. Anal Chim Acta 7:227-241.
  • Marco M, Chiron S, Gascon J, Hammock BD, Barcelo D. 1995. Validation of two immunoassay methods for environmental monitoring of carbaryl and 1-naphthol in ground water samples. Anal Chim Acta 311(3):319-329.
  • Schneider P, Gee SJ, Kreissig SB, Harris AS, Kramer PM, Marco M, Lucas AD, Hammock BD. 1995. Troubleshooting during the development and use of immunoassays for environmental monitoring. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.103-122.
  • Sundaram KM, Sundaram A, Gee SJ, Harrison RO, Hammock BD. 1995. Enzyme-linked immunosorb and assay for quantification of Bacillus thuringiensis var. kurstaki crystaline protein in commerical formulations, in relation to total protein content and insecticidal activity. In: Pesticide Formulations and Applicaiton Systems, 14th Volume. American Society for Testing and Materials, Philadelphia, PA.
  • Szekacs A, Hammock BD. 1995. Development of an enzyme-linked immunosorbent assay for the detection of the triazole fungicide myclobutanil. J Agric Food Chem 43(8):2083-2091.
  • Szekacs A, Jung F, Hammock BD. 1995. Chemical modification of haptens: Selective amino group protection by chromophores for an immunoassay for aminotriazoles. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.65-75.
  • Szurdoki F, Bekheit HK, Marco M, Goodrow MH, Hammock BD. 1995. Important factors in hapten design and enzyme-linked immunosorbent assay development. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.39-63.
  • Szurdoki F, Kido H, Hammock BD. 1995. Development of assay for analysis of Hg2+ based on sulfur-containing ligands. In: Immunoanalysis of Agrochemicals: Emerging Technologies (ACS Symposium Series 586). American Chemical Society, Washington, DC. pp.248-264.
  • Szurdoki F, Kido H, Hammock BD. 1995. Development of rapid mercury assays. Synthesis of sulfur-and mercury-containing conjugates. Bioconjug Chem 6(2):145-149.
  • Ward VK, Hammock BD, Maeda S, Choudary P. 1995. Development and application of recombinant antibodies to pesticide residue analysis. In: New Frontiers in Agrochemical Immunoassay. AOAC International, Arlington, VA. pp.197-216.
  • Ward VK, Kreissig SB, Hammock BD, Choudary P. 1995. Generation of an expression library in the baculovirus expression vector system. J Virol Methods 53(2-3):263-272. PMID:7673393
  • Wengatz I, Szurdoki F, Swamy AR, Evans L, Patonay G, Stimman E, Delwiche M, Stoutamire DW, Gee SJ, Hammock BD. 1995. Immunoassays for pesticide monitoring. SPIE Proceedings, San Jose, CA 408-416.
  • Wortberg M, Kreissig SB, Jones G, Rocke DM, Hammock BD. 1995. An immunoarray for the simultaneous determination of multiple triazine herbicides. Anal Chim Acta 304:339-352.

Share This Page:

Page Options:

Request Translation Services