Superfund Research Program
Detection and Models of Toxicant Exposure
Center Director: Robert H. Tukey
Grant Number: P42ES010337
Funding Period: 2000-2023
Program Links
Title: Murine hepatocellular carcinoma of AlbLTa/b transgenic mice and age matched C57BL/6 mice - 18 months old
Accession Number: E-GEOD-14467
Repository: ArrayExpress
Data Type(s): Gene Expression
Experiment Type(s): Comparative genomic hybridization by array
Organism(s): Mus musculus
Summary: aCGH analysis of murine transgenic liver tissues affected with HCC, hybridized with age (18 months) and sex matched C57BL/6 mice. Moreover, 18months old C57BL/6 livers were hybridized with independent 18 months old C57BL/6 livers for control. Keywords: Array comparative genomic hybridization analysis (aCGH). Independent HCC of AlbLTab mice were hybridized with independent C57BL/6 mice.
Publication(s) associated with this dataset:- Haybaeck J, Zeller N, Wolf MJ, Weber A, Kurrer M, Bremer J, lezzi G, Graf R, Clavien P, Ndeospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A, Heikenwalder M, Wagner U, Thimme R, Blum H. 2009. A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell 16(4):295-308. doi:10.1016/j.ccr.2009.08.021 PMID:19800575 PMCID:PMC4422166