Superfund Research Program
Molecular Mechanisms and Models for Exposure
Center Director: Robert H. Tukey
Grant Number: P42ES010337
Funding Period: 2000-2023
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Research BriefsConnect with the Grant Recipients
Projects and Cores funded in 2005-2010
Projects:
A Mouse Strain That Exhibits Elevated Sensitivity to Chemical Carcinogens and Hepatotoxins and the Mechanism Underlying That Increase
Project Leader: Michael Karin
Funding Period: 2000-2017
Cholinesterase Inhibition as a Target of Pesticide Residues and the Effect of Cholinergic Intervention on Gene Expression
Project Leader: Palmer W. Taylor
Funding Period: 2000-2010
Endocrine Disruptors in the Environment and their Influence
Project Leader: Christopher K. Glass
Funding Period: 2000-2010
Glutathione Conjugation of Environmental Toxins
Project Leader: Michael J. Kelner
Funding Period: 2000-2010
Microscale Engineered Liver Tissue for Toxicant Testing
Project Leader: Sangeeta N. Bhatia
Funding Period: 2005-2010
Molecular Mechanisms of Bacterial Metal Redox Transformations
Project Leader: Bradley M. Tebo (Oregon Health and Science University)
Funding Period: 2000-2010
Molecular Mechanisms of Heavy Metal Detoxification and Accumulation in Plants
Project Leader: Julian I. Schroeder
Funding Period: 2000-2017
The Expression in Mice of Human Xenobiotic Drug Metabolizing Genes Responsive to Ah Receptor Toxicants
Project Leader: Robert H. Tukey
Funding Period: 2000-2017
Toxicogenomic Analysis of Nuclear Xenobiotic Receptors, PXR and CAR, in Chemical Metabolism and Human Health
Project Leader: Ronald M. Evans (Salk Institute for Biological Studies)
Funding Period: 2005-2017
Yeast Genetics and Stress Response Genes
Project Leader: Paul Russell (The Scripps Research Institute)
Funding Period: 2000-2017
Cores:
Administrative Core
Project Leader: Robert H. Tukey
Funding Period: 2000-2023
Integrating Superfund-Related Science and Native Cultural Traditions
Project Leader: Keith Pezzoli
Funding Period: 2005-2023
Molecular Imaging
Project Leader: Mark H. Ellisman
Funding Period: 2005-2017
Mouse Genetics Core
Project Leader: Pamela L. Mellon
Funding Period: 2000-2017
Protein Characterization
Project Leader: Elizabeth A. Komives
Funding Period: 2005-2010
Research Translation Core: Applying Toxicogenomics and Biomolecular Technologies to Environmental Monitoring, Risk Assessment and Bioremediation
Project Leader: Keith Pezzoli
Funding Period: 2005-2023
Training Core
Project Leader: Palmer W. Taylor
Funding Period: 2000-2023