Skip Navigation

University of California-San Diego: Dataset Details, ID=GSE144864

Maintenance notice: We are currently addressing issues with broken links due to recent major website changes. We apologize for any inconvenience and appreciate your patience. Please contact brittany.trottier@niehs.nih.gov for assistance.

Superfund Research Program

Detection and Models of Toxicant Exposure

Center Director: Robert H. Tukey
Grant Number: P42ES010337
Funding Period: 2000-2023
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

Program Links

Connect with the Grant Recipients

Visit the grantee's eNewsletter page Visit the grantee's Instagram page Visit the grantee's Facebook page

Title: NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegaly (RNA-seq dataset 2)

Accession Number: GSE144864

Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE144864

Repository: Gene Expression Omnibus (GEO)

Data Type(s): Gene Expression

Experiment Type(s): Expression profiling by high throughput sequencing

Organism(s): Mus musculus

Summary: The goal of this study is to provide the liver metabolic changes in the liver specific constitutively NRF2 activated (Nrf2Act-hep) mice. Overall design: RNAs were extracted from livers of 6 week-old Wild Type (WT) B6 and Nrf2Act-hep mice for RNA-seq analysis.

Publication(s) associated with this dataset:
  • He F, Antonucci L, Yamachika S, Zhang Z, Taniguchi K, Umemura A, Hatzivassiliou G, Roose-Girma M, Reina-Campos M, Molina AD, Diaz-Meco MT, Moscat J, Sun B, Karin M. 2020. NRF2 activates growth factor genes and downstream AKT signaling to induce mouse and human hepatomegaly. J Hepatol 72:1182-1195. doi:10.1016/j.jhep.2020.01.023 PMID:32105670
Back
to Top