Superfund Research Program
The MIT Superfund Research Program: A Systems Approach for the Protection of Human Health from Hazardous Chemicals
Center Director: Bevin P. Engelward
Grant Number: P42ES027707
Funding Period: 2017-2027
News Items List
Studying DNA Damage and Repair Unlocks Key to Cancer Treatments
Environmental Factor - September 2023
How the body repairs DNA damage following exposure to a chemical called N-nitrosodimethylamine (NDMA) can provide new insights for cancer treatment, according to Jennifer Kay, Ph.D. The former Massachusetts Institute of Technology SRP Center trainee presented her findings during the August 1 Wetterhahn Award Seminar.
Tackling Environmental Health Problems from Many Angles
Environmental Factor - July 2023
Current and upcoming research to address complex environmental health issues related to hazardous contaminants, climate-related disasters, and more, headlined the recent NIEHS Superfund Research Program (SRP) Progress in Research webinar series. Over the course of four sessions in April and May, the series highlighted 11 new and renewed SRP multiproject centers funded in 2022.
Exposure to NDMA Causes Tell-Tale Mutational Pattern
SRP News Page - June 2023
Researchers with the NIEHS-funded Massachusetts Institute of Technology (MIT) Superfund Research Program (SRP) Center have found distinctive genetic patterns signifying damage from the toxic chemical N-nitrosodimethylamine, or NDMA. The patterns could potentially be used to monitor cancer development and inform therapeutic interventions.
New Resource Guides Community Groups Struggling with Environmental Cleanups
SRP News Page - June 2023
NIEHS-funded researchers recently developed a new online course to aid concerned residents and other community members through the process of cleaning up environmental contamination. The course includes educational and interactive modules, short videos, and questions for reflection to help guide participants to identify and address chemical exposures in their homes, neighborhoods, and local communities.
SRP Centers Share Science With Students
SRP News Page - May 2023
A key goal of the NIEHS Superfund Research Program (SRP) is to train future generations of scientists - in the lab and in the community. SRP Centers across the country have been doing just that, participating in community events to teach school-aged children about science.
SRP Highlighted at SOT
SRP News Page - April 2023
NIEHS Superfund Research Program (SRP)-funded scientists from across the country gathered in person for the 2023 Society of Toxicology (SOT) Annual Meeting to share their research and exchange ideas. Held March 19 - 23 in Nashville, Tennessee, the 62nd SOT meeting and ToxExpo drew more than 5,000 attendees who gave more than 2,000 presentations and participated in more than 70 sessions.
SRP Shines at SOT
SRP News Page - April 2022
NIEHS Superfund Research Program (SRP) grantees from across the country gathered in person and virtually for the 2022 Society of Toxicology (SOT) Annual Meeting, held March 27-31 in San Diego. The meeting highlighted diverse, cutting-edge research.
SRP Teams Tackle Pandemic Challenges from Many Angles
SRP News Page - March 2022
Throughout the COVID-19 pandemic, NIEHS Superfund Research Program (SRP) teams have shown resourcefulness, updating existing projects and pursuing new research to address environmental health needs.
Combined Approach Sheds Light on Global Cancer Risk
Research Brief - December 2021
About 90 percent of the global lung cancer risk from polycyclic aromatic hydrocarbons (PAHs) does not come from benzo(a)pyrene, according to a study funded by the NIEHS Superfund Research Program (SRP). Some of these compounds are not regularly monitored.
Three-Dimensional Cell Model Enhances DNA Damage Testing
Research Brief - June 2020
Superfund Research Program (SRP) Center scientists developed a new platform, known as the SpheroidChip analysis method, to rapidly test for DNA damage in three-dimensional (3D) cell models. Development was led by Bevin Engelward, Sc.D., at the Massachusetts Institute of Technology.
New quick screen for different types of DNA damage
Paper of the Month - February 2020
NIEHS grantees developed a new screening method that can detect a broad range of DNA damage in cells. According to the authors, this new method fills a gap in DNA damage testing and could make chemical safety testing faster, easier, and more accurate.
Nanotube Sensor Detects Nitrosamines in Air
Research Brief - December 2019
Massachusetts Institute of Technology Superfund Research Program researchers have developed a sensitive and inexpensive carbon nanotube-based sensor that can measure N-nitrosamines in air.
Supplements Expand SRP's Capacity for Data Sharing
SRP News Page - October 2019
The Superfund Research Program (SRP) awarded administrative supplements to its Multiproject Center (P42) and Individual Research (R01) grantees to expand data integration, interoperability, and reuse. The SRP encourages data sharing among its grantees to accelerate new discoveries, stimulate new collaborations, and increase scientific transparency and rigor.
New tool rapidly evaluates chemical effects on cells
Paper of the Month - April 2019
NIEHS grantees have developed a new toxicity test that can measure the effects of chemicals on cell survival. The tool is much faster than the gold standard cell survival tool and more sensitive than other rapid cell toxicity tests.
SRP Grantees Develop a Better Way to Measure Cell Survival
SRP News Page - March 2019
Researchers from the Massachusetts Institute of Technology (MIT) Superfund Research Program (SRP) Center recently developed a new test that rapidly measures the effect of different chemicals on cell survival. Measuring cell survival is critical for screening potentially toxic chemicals and protecting human health. The technology was developed as part of an NIEHS small business grant, with partial funding from the MIT SRP Center.
Eight Northeast SRP Centers Convene at Regional Meeting
SRP News Page - April 2018
The Northeast Superfund Research Program (SRP) Meeting brought together eight SRP Centers to discuss collaborations and network. Held in Woods Hole, Massachusetts, on March 26 - 27, the meeting included scientific presentations and poster sessions.