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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Research Briefs: Michigan State University

Superfund Research Program

Environmental, Microbial and Mammalian Biomolecular Responses to AhR Ligands

Center Director: Norbert E. Kaminski
Grant Number: P42ES004911
Funding Period: 1989-2027
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Research Briefs

  • 337 - Dioxin Disrupts Liver Cells in Mice, Potential Link with Liver Disease -- Zacharewski, Nault
    Release Date: 01/11/2023

    An NIEHS Superfund Research Program (SRP)-funded study in mice reported that exposure to a type of dioxin can alter cells in the liver, their metabolic characteristics, and how they are organized within the liver. According to the researchers, these changes in cell behavior and organization play a role in the development of dioxin-induced liver diseases, such as fibrosis and fatty liver disease.

  • 312 - Improved Sequencing Method Leads to Advancements in Toxicology Research -- Zacharewski
    Release Date: 12/02/2020

    NIEHS-funded Superfund Research Program (SRP) scientists are employing a new RNA sequencing method to assess mechanisms of toxicity on a finer and more accessible scale. Researchers in SRP grantee Tim Zacharewski's Lab at the Michigan State University (MSU) SRP Center conducted the study.

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Last Reviewed: April 09, 2025