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North Carolina State University

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Superfund Research Program

Core of Advanced Platform Technologies Used for Remediation and Exploration (CAPTURE)

Project Leader: David C. Muddiman
Co-Investigator: Erin S. Baker (University of North Carolina-Chapel Hill)
Grant Number: P42ES031009
Funding Period: 2020-2025
View this project in the NIH Research Portfolio Online Reporting Tools (RePORT)

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Project Summary (2020-2025)

Responding to newly discovered environmental contaminants requires novel analytical approaches. The Core of Advanced Platform Technologies Used for Remediation and Exploration (CAPTURE) provides analytical capabilities to the four projects to enable rapid, comprehensive assessment of PFAS presence. CAPTURE is composed of the Genomic Sciences Laboratory (GSL); the Analytical Instrumentation Facility (AIF); and the Molecular Education, Technology, and Research Innovation Center (METRIC) at North Carolina State University, which have over $25 million in modern instrumentation and are operated by more than 20 Ph.D.-level, highly qualified personnel. These capabilities provide CAPTURE with the ability to explore the diversity of scientific questions with a broad range of measurements including RNA-seq, materials characterization, and mass spectrometry analyses for the known and unknown per- and polyfluoroalkyl substances (PFAS). New methods and reagents are resulting from this work, which is enabling and informing the entire scientific community about PFAS in the environment. Additionally, CAPTURE enhances interactions among Center projects and other cores, increasing their impact by ensuring synchronization of exposure measurements and increasing their value in decision making, translation, and community engagement.

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