Superfund Research Program

May 2022

Paper of the Month or Year

An SRP-funded study in mice showed that prenatal exposure to polychlorinated biphenyls (PCBs) altered DNA methylation in both the placenta and fetal brain in a manner consistent with neurodevelopmental disorders. The research was conducted at the University of California, Davis SRP Center.

According to the authors, DNA methylation profiles of placenta with measured PCB exposures could serve as predictive biomarkers to enable early intervention of PCB-associated neurodevelopmental disorders.

Read more in the NIEHS Environmental Factor Newsletter.