Superfund Research Program
Title: A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers
Accession Number: GSE72353
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE72353
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Expression profiling by array
Organism(s): Homo sapiens
Summary: Gene expression changes linked to two step immortalization of human mammary epithelial cells (HMEC). A lincRNA, MORT, associated with the mortal state, was identified MORT is silenced by DNA methylation in immortal mammary epithelial cells
Publication(s) associated with this dataset:- Vrba L, Garbe JC, Stampfer MR, Futscher BW. 2015. A lincRNA connected to cell mortality and epigenetically-silenced in most common human cancers. Epigenetics 10(11):1074-1083. doi:10.1080/15592294.2015.1106673 PMID:26646903 PMCID:PMC4844203
- University of Arizona: Epigenomic Actions of Environmental Arsenicals