Superfund Research Program
Title: Histone modifications in primary intestinal epithelial cells from wild type (F/FUN) and intesinal NCoR1 deletion (ΔIECUN) neonates.
Accession Number: GSE86996
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE86996
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Genome binding/occupancy profiling by high throughput sequencing
Organism(s): Mus musculus
Summary: ChIP-seq analyses were carried out in intestinanl epithelial cells (IECs) isolated from F/FUN and ΔIECUN mice to assess histone modifications across the genome, an event that links the actions of corepressors with molecular insight towards a mechanism.
Publication(s) associated with this dataset:- Chen S, Lu W, Yueh MF, Rettenmeier E, Liu M, Auwerx J, Yu RT, Evans RM, Wang K, Karin M, Tukey RH. 2017. Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia. Proc Natl Acad Sci U S A 114(8):E1432-E1440. doi:10.1073/pnas.1700232114 PMID:28167773 PMCID:PMC5338369
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