Superfund Research Program
Title: Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway [methylation]
Accession Number: GSE73375
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE73375
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Methylation profiling by genome tiling array
Organism(s): Homo sapiens
Summary: Placental Tissue Samples from 36 women (17 normotensive women, denoted with a P, and 19 preeclamptic women, denoted with a Q) were analyzed for differenital methylation. Preeclamptic womene were compared direclty to normotensive women controlling for gestational age, race, maternal age, and baby sex.
Publication(s) associated with this dataset:- Martin EA, Ray PD, Smeester L, Grace MR, Boggess K, Fry RC. 2015. Epigenetics and preeclampsia: defining functional epimutations in the preeclamptic placenta related to the TGF-β pathway. PLoS One 10(10):e0141294. doi:10.1371/journal.pone.0141294 PMID:26510177 PMCID:PMC4624949
- University of North Carolina-Chapel Hill: Elucidating Mechanisms of Heavy Metal-Induced Toxicity and Disease