Superfund Research Program
Title: Orphan Nuclear Receptor ERRγ is required for pancreatic islet beta-cell maturation
Accession Number: GSE56080
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE56080
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Expression profiling by array
Organism(s): Mus musculus
Summary: We characterized the effect of loss of ERRγ expression in mouse pancreatic islets using adenoviral constructs.
Publication(s) associated with this dataset:- Yoshihara E, Wei Z, Lin CS, Fang S, Ahmadian M, Kida Y, Tseng TW, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. 2016. ERRγ is required for the metabolic maturation of therapeutically functional glucose-responsive β cells. Cell Metab 23(4):622-634. doi:10.1016/j.cmet.2016.03.005 PMID:27076077 PMCID:PMC4832237
- University of California-San Diego: Toxicogenomic Analysis of Nuclear Xenobiotic Receptors