Superfund Research Program
Title: RNA-seq of maturation stage pituitary mouse cell lines and NIH-3T3
Accession Number: GSE104513
Link to Dataset: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE104513
Repository: Gene Expression Omnibus (GEO)
Data Type(s): Gene Expression
Experiment Type(s): Array expression profiling by high throughput sequencing
Organism(s): Mus musculus
Summary: Proper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for reproduction. We performed RNAseq of 3 maturaton staged gonadotrope cell lines, a thyroptrope cell line and NIH-3T3 cells to establish the timing and expression levels of genes involved in gonadotrope maturation.
Publication(s) associated with this dataset:- Xie H, Hoffmann HM, Iyer AK, Brayman MJ, Ngo C, Sunshine M, Mellon PL. 2017. Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. Reprod Biol Endocrinol 15(1):86. doi:10.1186/s12958-017-0304-z PMID:29065928 PMCID:PMC5655979
- University of California-San Diego: Genetics and Metabolomics Core
- University of California-San Diego: Mouse Molecular Genetics Core