Title: Fatty Liver and Impaired Hepatic Metabolism Alter the Congener-specific Distribution of Polychlorinated Biphenyls (PCBs) in Mice with A Liver-specific Deletion of Cytochrome P450 Reductase

Accession Number: doi:10.25820/data.006117

Link to Dataset: https://doi.org/10.25820/data.006117

Repository: Iowa Research Online

Data Type(s): Exposure Data

Organism(s): Mus musculus

Summary: This excel data sheet summarizes quality assurance /quality control (QA/QC) data, including method detection limits (MDL), recovery rates of spiked ongoing precision and recovery standards (OPR) in both blank solvent and tissue matrix, limits of detection in both mass (ng) and concentration (ng/g tissue) from a study investigating the congener specific tissue distribution in mice exposed orally to Aroclor 1254. In addition, data from individual animals are tabulated for PCB homolog group, PCB Class, or individual levels congeners, as appropriate.

Publication(s) associated with this dataset:

• Li X, Zhang C, Wang K, Lehmler H. 2020. Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorinated biphenyls (PCBs) in mice with a liver-specific deletion of cytochrome P450 reductase. Environ Pollut 266:115233. doi:10.1016/j.envpol.2020.115233 PMID:32712482 PMCID:PMC7492420

Project(s) associated with this dataset:

• University of Iowa: Research Support Core: Synthesis Core