Superfund Research Program
Title: A dataset pertaining to the sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ cells and on transcriptomic profiles and diabetic phenotype of offspring
Accession Number: doi: 10.15139/S3/XUO3X9
Link to Dataset: https://dataverse.unc.edu/dataset.xhtml?persistentId=doi:10.15139/S3/XUO3X9
Repository: Dataverse
Data Type(s): Gene Expression, Underlying data from publication
Summary: RNA sequencing was conducted to evaluate transcriptional status in sperm and oocytes of C57BL/6J mice exposed to 200ppb of sodium arsenite. Gene expression was also evaluated in off spring livers and islets that were exposed to inorganic arsenic prior to conception.
Publication(s) associated with this dataset:- Venkatratnam A, Douillet C, Topping BC, Shi Q, Addo KA, Ideraabdullah FY, Fry RC, Styblo M. 2020. Sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ cells and on transcriptomic profiles and diabetic phenotype of offspring. Arch Toxicol doi:10.1007/s00204-020-02941-w PMID:33145626
- University of North Carolina-Chapel Hill: Arsenic-Obesity-Diabetes Interactions
- University of North Carolina-Chapel Hill: Molecular Drivers of Arsenic-Induced Diabetes