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National Institute of Environmental Health Sciences

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Your Environment. Your Health.

Dataset Details (doi: 10.15139/S3/XUO3X9)

Superfund Research Program

Title: A dataset pertaining to the sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ cells and on transcriptomic profiles and diabetic phenotype of offspring

Accession Number: doi: 10.15139/S3/XUO3X9

Link to Dataset: https://dataverse.unc.edu/dataset.xhtml?persistentId=doi:10.15139/S3/XUO3X9

Repository: Dataverse

Data Type(s): Gene Expression, Underlying data from publication

Summary: RNA sequencing was conducted to evaluate transcriptional status in sperm and oocytes of C57BL/6J mice exposed to 200ppb of sodium arsenite. Gene expression was also evaluated in off spring livers and islets that were exposed to inorganic arsenic prior to conception.

Publication(s) associated with this dataset:
  • Venkatratnam A, Douillet C, Topping BC, Shi Q, Addo KA, Ideraabdullah FY, Fry RC, Styblo M. 2020. Sex-dependent effects of preconception exposure to arsenite on gene transcription in parental germ cells and on transcriptomic profiles and diabetic phenotype of offspring. Arch Toxicol doi:10.1007/s00204-020-02941-w PMID:33145626
Project(s) associated with this dataset:
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