Superfund Research Program


September 2022

Image of the sensor
The sensor contains engineered bacterial strains designed to fluoresce in the presence of specific water contaminants. (Photo courtesy of Quantitative BioSciences, Inc.)


Quantitative BioSciences, Inc., has developed a customizable sensor to continuously monitor water for arsenic, mercury, and cadmium, among other contaminants. A Business Innovation Research Grant from the NIEHS Superfund Research Program supported early work on the device.

The sensor employs a quarter-sized cartridge that can house many different bacterial strains, each engineered to fluoresce when it detects a specific contaminant. A machine learning platform, embedded in the device, translates those light signals into concentrations. Once deployed, the sensors can collect an ongoing stream of data on multiple contaminants simultaneously for at least a month, after which cartridges are easily replaced.

TechnologyA customizable sensor for continuously monitoring water for contaminants.
InnovationThe sensor employs engineered bacterial strains designed to fluoresce in response to contaminants of interest in water. Machine learning translates those signals into concentrations. Once deployed, the sensor collects a continuous stream of data on many contaminants simultaneously, without intervention, for 30 days.
Contaminant and MediaArsenic, cadmium, iron, mercury, lead, manganese, copper, zinc, uranium, nitrate, nitrite, ammonium, and phosphate
Technology Readiness Level7
Principal InvestigatorScott Cookson, Ph.D.
InstitutionQuantitative BioSciences, Inc.
Grant NumberR43ES028993