Project Summary (2000-2006)

The Trace Metals Research Support Core Laboratory enables numerous investigators to precisely measure a broad range of metals in biological specimens, including Pb, As, and a host of other metals and metaloproteins. The NIEHS Center provides support for instrumentation, service contracts, methods development, and pilot study analyses. Three biomedical projects (1,3,4) require large numbers of trace metal analyses in urine and/or blood samples. The analyses include blood Pb analyses, total urinary As analyses, and urinary inorganic arsenic (InAs), monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA). The Trace Metal Core Laboratory also provides investigators with bar-coded metal-free urine and blood collection tubes.