Superfund Research Program

Search Results

Toxicology Letters (60 articles)

2023

• Walls KM, Hong KU, Hein DW. 2023. Induction of glucose production by heterocyclic amines is dependent on N-acetyltransferase 2 genetic polymorphism in cryopreserved human hepatocytes. Toxicol Lett 383:192-195. doi:10.1016/j.toxlet.2023.07.002 PMID:37423373

2021

• Medina S, Bolt AM, Zhou X, Wan G, Xu H, Lauer FT, Liu K, Burchiel SW. 2021. Arsenite and monomethylarsonous acid disrupt erythropoiesis through combined effects on differentiation and survival pathways in early erythroid progenitors. Toxicol Lett 350:111-120. doi:10.1016/j.toxlet.2021.07.008 PMID:34274428 PMCID:PMC8487637

2020

• Dashner-Titus EJ, Schilz JR, Simmons KA, Duncan TR, Alvarez SC, Hudson LG. 2020. Differential response of human T-lymphocytes to arsenic and uranium. Toxicol Lett 333:269-278. doi:10.1016/j.toxlet.2020.08.013 PMID:32866568 PMCID:PMC7590629

2019

• Hennig B, Petriello MC. 2019. Nutritional modulation of environmental toxicity and implications in inflammatory diseases. Toxicol Lett 314:S88. doi:10.1016/j.toxlet.2019.09.002

2018

• Hein DW, Zhang X, Doll MA. 2018. Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation. Toxicol Lett 283:100-105. doi:10.1016/j.toxlet.2017.11.028 PMID:29180287 PMCID:PMC5745265
• Spade DJ, Bai CY, Lambright C, Conley JM, Boekelheide K, Gray LE. 2018. Validation of an automated counting procedure for phthalate-induced testicular multinucleated germ cells. Toxicol Lett 290:55-61. doi:10.1016/j.toxlet.2018.03.018 PMID:29571896 PMCID:PMC5921076

2017

• Oliva-Gonzalez C, Uresti-Rivera E, Galicia-Cruz O, Jasso-Robles F, Gandolfi A, Escudero-Lourdes C. 2017. The tumor suppressor phosphatase and tensin homolog protein (PTEN) is negatively regulated by NF-kappa b p50 homodimers and involves histone 3 methylation/deacetylation in UROtsa cells chronically exposed to monomethylarsonous acid. Toxicol Lett 280:92-98. doi:10.1016/j.toxlet.2017.08.013 PMID:28823542
• Smith JN, Mehinagic D, Nag S, Crowell SR, Corley RA. 2017. In vitro metabolism of benzo[a]pyrene-7,8-dihydrodiol and dibenzo[def,p]chrysene-11,12 diol in rodent and human hepatic microsomes. Toxicol Lett 269:23-32. doi:10.1016/j.toxlet.2017.01.008 PMID:28119020

2016

• Carratt SA, Morin D, Buckpitt AR, Edwards PC, Van Winkle LS. 2016. Naphthalene cytotoxicity in microsomal epoxide hydrolase deficient mice. Toxicol Lett 246:35-41. doi:10.1016/j.toxlet.2016.01.019 PMID:26840748 PMCID:PMC4774530
• Kodani SD, Overby HB, Morisseau C, Chen J, Zhao L, Hammock BD. 2016. Parabens inhibit fatty acid amide hydrolase: a potential role in paraben-enhanced 3T3-L1 adipocyte differentiation. Toxicol Lett 262:92-99. doi:10.1016/j.toxlet.2016.09.011 PMID:27659731 PMCID:PMC5096949
• Stanford EA, Wang Z, Novikov O, Ramirez-Cardenas A, Mulas F, Landesman-Bollag E, Monti S, Smith BW, Bais MV, Kukuruzinska M, Murphy GJ, Sherr DH. 2016. A role for the aryl hydrocarbon receptor (Ahr) in the production and function of breast and oral cancer stem-like cells and the potential therapeutic value of Ahr modulators. Toxicol Lett 259:S20. doi:10.1016/j.toxlet.2016.07.090

2015

• Samokhvalov V, Zlobine I, Jamieson KL, Jurasz P, Chen C, Lee KS, Hammock BD, Seubert JM. 2015. PPARδ signaling mediates the cytotoxicity of DHA in H9c2 cells. Toxicol Lett 232(1):10-20. doi:10.1016/j.toxlet.2014.09.029 PMID:25300478 PMCID:PMC4486642
• Xiao W, Son J, Vorrink SU, Domann FE, Goswami PC. 2015. Ligand-independent activation of aryl hydrocarbon receptor signaling in PCB3-quinone treated HaCaT human keratinocytes. Toxicol Lett 233(3):258-266. doi:10.1016/j.toxlet.2015.02.005 PMID:25668756 PMCID:PMC4341842

2014

• Costa LG, de Laat R, Tagliaferri S, Pellacani C. 2014. A mechanistic view of polybrominated diphenyl ether (PBDE) developmental neurotoxicity. Toxicol Lett 230(2):282-294. doi:10.1016/j.toxlet.2013.11.011 PMID:24270005 PMCID:PMC4028440

2013

• Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Anzenbacher P, Dvorak Z. 2013. Pelargonidin activates the AhR and induces CYP1A1 in primary human hepatocytes and human cancer cell lines HepG2 and LS174T. Toxicol Lett 218(3):253-259. doi:10.1016/j.toxlet.2013.01.020 PMID:23419638 PMCID:PMC3644221
• Kamenickova A, Anzenbacherova E, Pavek P, Soshilov AA, Denison MS, Zapletalova M, Anzenbacher P, Dvorak Z. 2013. Effects of anthocyanins on the AhR-CYP1A1 signaling pathway in human hepatocytes and human cancer cell lines. Toxicol Lett 221(1):1-8. doi:10.1016/j.toxlet.2013.05.007 PMID:23735880 PMCID:PMC3759295
• Nault R, Forgacs AL, Dere E, Zacharewski TR. 2013. Comparisons of differential gene expression elicited by TCDD, PCB126, βNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver. Toxicol Lett 223(1):52-59. doi:10.1016/j.toxlet.2013.08.013 PMID:23994337 PMCID:PMC4096832

2012

• Lesseur C, Gilbert-Diamond D, Andrew AS, Ekstrom RM, Li Z, Kelsey KT, Marsit CJ, Karagas MR. 2012. A case-control study of polymorphisms in zenobiotic and arsenic metabolism genes and arsenic-related bladder cancer in New Hampshire. Toxicol Lett 210:100-106. doi:10.1016/j.toxlet.2012.01.015 PMID:22306368 PMCID:PMC3374400
• Shen H, Robertson LW, Ludewig G. 2012. Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male Sprague Dawley rats. Toxicol Lett 209(3):291-298. doi:10.1016/j.toxlet.2012.01.003 PMID:22266287 PMCID:PMC3288253

2011

• Senthilkumar PK, Klingelhutz AJ, Jacobus JA, Lehmler H, Robertson LW, Ludewig G. 2011. Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat). Toxicol Lett 204:64-70. doi:10.1016/j.toxlet.2011.04.012 PMID:21530622 PMCID:PMC3109099

2010

• Bolt AM, Douglas R, Klimecki WT. 2010. Arsenite exposure in human lymphoblastoid cell lines induces autophagy and coordinated induction of lysosomal genes. Toxicol Lett 199(2):153-159. doi:10.1016/j.toxlet.2010.08.017 PMID:20816728 PMCID:PMC2956852
• Venkatesha VA, Kalen AL, Sarsour EH, Goswami PC. 2010. PCB-153 exposure coordinates cell cycle progression and cellular metabolism in human mammary epithelial cells. Toxicol Lett 196(2):110-116. doi:10.1016/j.toxlet.2010.04.005 PMID:20394812 PMCID:PMC2891036

2009

• Andrew AS, Mason RA, Kelsey KT, Schned AR, Marsit CJ, Nelson HH, Karagas MR. 2009. DNA repair genotype interacts with arsenic exposure to increase bladder cancer risk. Toxicol Lett 187(1):10-14. doi:10.1016/j.toxlet.2009.01.013 PMID:19429237 PMCID:PMC2680739
• Arzuaga X, Ren N, Stromberg AJ, Black EP, Arsenescu V, Cassis LA, Majkova Z, Toborek M, Hennig B. 2009. Induction of gene pattern changes associated with dysfunctional lipid metabolism induced by dietary fat and exposure to a persistent organic pollutant. Toxicol Lett 189(2):96-101. doi:10.1016/j.toxlet.2009.05.008 PMID:19467301 PMCID:PMC2729430
• Rodriguez-Fuentes G, Coburn C, Currás-Collazo M, Schlenk D, Guillén G. 2009. Effect of hyperosmotic conditions on flavin-containing monooxygenase activity, protein and mRNA expression in rat kidney. Toxicol Lett 187(2):115-118. doi:10.1016/j.toxlet.2009.02.006 PMID:19429252 PMCID:PMC2858923

2008

• Kim D, Farthing MW, Miller CT, Nylander-French LA. 2008. Mathematical description of the uptake of hydrocarbons in jet fuel into the stratum corneum of human volunteers. Toxicol Lett 178(3):146-151. doi:10.1016/j.toxlet.2008.03.005 PMID:18423910 PMCID:PMC2443700
• Oesteriing E, Chopra N, Gavalas VG, Arzuaga X, Lim EJ, Sultana R, Butterfield DA, Bachas LG, Hennig B. 2008. Alumina nanoparticles induce expression of endothelial cell adhesion molecules. Toxicol Lett 178(3):160-166. doi:10.1016/j.toxlet.2008.03.011 PMID:18456438
• Wang F, Sobel ES, Butfiloski EJ, Roberts SM. 2008. Comparison of chlordecone and estradiol effects on splenic T-cells in (NZBxNZW)F(1) mice. Toxicol Lett 183(1-3):1-9. doi:10.1016/j.toxlet.2008.08.020 PMID:18951962

2007

• Heyer NJ, Bittner AC, Echeverria D, Woods JS. 2007. Reply to the Letter to the Editor: Response to comment on: " A cascade analysis of the interaction of mercury and coproporphyrinogen oxidase (CPOX) polymorphism on the heme biosynthetic pathway and porphyrin production" by Heyer et al [Toxicol Lett 1612006 159-166]. Toxicol Lett 169(1):93-94. doi:10.1016/j.toxlet.2006.11.011 PMID:17987105
• Kibriya MG, Jasmine F, Argos M, Verret WJ, Rakibuz-Zaman M, Ahmed A, Parvez F, Ahsan H. 2007. Changes in gene expression profiles in response to selenium supplementation among individuals with arsenic-induced pre-malignant skin lesions. Toxicol Lett 169(2):162-176. doi:10.1016/j.toxlet.2007.01.006 PMID:17293063 PMCID:PMC1924917

2006

• Barhoumi R, Awooda I, Mouneimne Y, Safe SH, Burghardt RC. 2006. Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells. Toxicol Lett 165(2):133-141. PMID:16567066
• Kim D, Andersen ME, Nylander-French LA. 2006. Dermal absorption and penetration of jet fuel components in humans. Toxicol Lett 165(1):11-21. doi:10.1016/j.toxlet.2006.01.009 PMID:16497449
• Kunz S, Schwarz M, Schilling B, Papke O, Lehmler H, Robertson LW, Schrenk D, Schmitz H. 2006. Tumor promoting potency of PCBs 28 and 101 in rat liver. Toxicol Lett 164(2):133-143. PMID:16426774
• Peters AK, Leonards PE, Zhao B, Bergman A, Denison MS, van den Berg M. 2006. Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal. Toxicol Lett 165(3):230-241. PMID:16750337
• Ptak A, Ludewig G, Kapiszewska M, Magnowska Z, Lehmler H, Robertson LW, Gregoraszczuk EL. 2006. Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary. Toxicol Lett 166(3):200-211. PMID:16949219
• Ptak A, Ludewig G, Robertson LW, Lehmler H, Gregoraszczuk EL. 2006. In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: Effects on sex hormone levels and aromatase activity. Toxicol Lett 164(2):113-122. PMID:16412591

2003

• Ahsan H, Chen Y, Wang Q, Slavkovich VN, Graziano JH, Santella RM. 2003. DNA repair gene XPD and susceptibility to arsenic-induced hyperkeratosis. Toxicol Lett 143(2):123-131. doi:10.1016/S0378-4274(03)00117-6 PMID:12749816
• Sabri MI, Hashemi SB, Spencer PS. 2003. Neurotoxicity and reactivity of 1,2-diacetylbenzene (1,2-DAB) with motor and cytoskeletal proteins in rat spinal cord and sciatic nerves. Toxicol Lett 144(Suppl.1):s130.
• Spiegelstein O, Lu X, Le X, Troen A, Selhub J, Melnyk SB, James S, Finnell RH. 2003. Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicol Lett 145(2):167-174. doi:10.1016/S0378-4274(03)00307-2 PMID:14581169
• Tampal N, Myers S, Robertson LW. 2003. Binding of polychlorinated biphenyls/metabolites to hemoglobin. Toxicol Lett 142(1-2):53-60. PMID:12765239

2002

• Cangul H, Broday L, Salnikow K, Sutherland JE, Peng W, Zhang Q, Poltaratsky V, Yee H, Zoroddu MA, Costa M. 2002. Molecular mechanisms of nickel carcinogenesis. Toxicol Lett 127(1-3):69-75. PMID:12052643
• Pierce RH, Chen Y, Dills RL, Morgan MS, Kalman DA. 2002. Toluene metabolites as biological indicators of exposure. Toxicol Lett 129(1-2):65-76. PMID:11879975

2001

• Diaz D, Krejsa CM, Kavanagh TJ. 2001. Localization of glutamate-cysteine ligase mRNA and protein in mouse kidney and induction with methylmercury. Toxicol Lett 123(1):33-41. PMID:11514103
• Diaz D, Krejsa CM, White CC, Keener CL, Farin FM, Kavanagh TJ. 2001. Tissue specific changes in the expression of glutamate-cysteine ligase mRNAs in mice exposed to methylmercury. Toxicol Lett 122(2):119-129. PMID:11439218

2000

• Chun H, Kuzmicky A, Rucoba L, Kado NY, Rice RH. 2000. Cytotoxicity and keratinocyte microsome mediated mutagenic activation of carcinogens in cultured epidermal cells. Toxicol Lett 115(2):165-172. PMID:10802392
• Ruan Y, Petersen MH, Wauson EM, Gelineau-van Waes J, Vorce RL, Finnell RH. 2000. Folic acid protects SWV/Fnn embryo fibroblasts against arsenic toxicity. Toxicol Lett 117:129-137. PMID:11087978
• Sabri MI, Kim M, Spencer PS. 2000. The aromatic hydrocarbon 1,2-diacetylbenzene induces pathological changes in the rodent nervous system. Toxicol Lett 116(1):72.
• Vakharia D, Gierthy JF. 2000. Use of a combined human liver microsome-estrogen receptor assay to assess potential estrogen modulating activity of PCB metabolites. Toxicol Lett 114(1-3):55-65. PMID:10713469

1999

• Rappaport SM, Yeowell-O'Connell K. 1999. Protein adducts as dosimeters of human exposure to styrene, styrene-7, 8-oxide, and benzene. Toxicol Lett 108:117-126. PMID:10511253
• Thompson SA, White CC, Krejsa CM, Diaz D, Woods JS, Kavanagh TJ. 1999. Induction of glutamate-cysteine ligase in the brains of adult female mice sub-chronically exposed to methylmercury. Toxicol Lett 110:1-10. PMID:10593589

1998

• Marion M. 1998. Critical genes as early warning signs: example of vinyl chloride. Toxicol Lett 102/103:603-607. PMID:10022320
• Safe SH, Connor K, Gaido KW. 1998. Methods for xenoestrogen testing. Toxicol Lett 102/103:661-666. PMID:10022332
• Trosko JE, Chang C, Upham BL, Wilson MR. 1998. Epigenetic toxicology as toxicant-induced changes in intracellular signalling leading to altered gap junctional intercellular communication. Toxicol Lett 102-103:71-78. PMID:10022235

1996

• Leung LK, Glauert HP. 1996. Reduction of the concentrations of prostaglandins E₂ and F_2±, and thromboxane b₂ in cultured rat hepatocytes treated with the peroxisome proliferator ciprofibrate. Toxicol Lett 85(3):143-149.
• Swenberg JA, La DK, Scheller NA, Wu K. 1996. Dose-response relationships for carcinogens. Toxicol Lett 82-3:751-756. PMID:8597138

1995

• Costa LG, Manzo L. 1995. Biochemical markers of neurotoxicity: research strategies and epidemiological applications. Toxicol Lett 77(1-3):137-144. PMID:7618127
• Manzo L, Castoldia AF, Coccinia T, Rossia AD, Nicoteraa P, Costa LG. 1995. Mechanisms of neurotoxicity: applications to human biomonitoring. Toxicol Lett 77(1-3):63-72. PMID:7618170
• Yang RH, El-Masri HA, Thomas RS, Constan AA. 1995. The use of physiologically based pharmacokinetic/pharmacodynamic dosimetry models for chemical mixtures. Toxicol Lett 82/83:497-504. PMID:8597101
• Yang RH, El-Masri HA, Thomas RS, Constan AA, Tessari JD. 1995. The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixtures. Toxicol Lett 79(1-3):193-200. PMID:7570656
• Zhao F, Mayura K, Hutchinson RW, Lewis RP, Burghardt RC, Phillips TD. 1995. Developmental toxicity and structure-activity relationships of chlorophenols using human embryonic palatal mesenchymal cells. Toxicol Lett 78(1):35-42. doi:10.1016/0378-4274(95)99684-A PMID:7604397