Superfund Research Program

Nature (impact factor: 49.962)

2024

• Gentry E, Collins S, Panitchpakdi M, Belda-Ferre P, Stewart AK, Carrillo Terrazas M, Lu H, Zuffa S, Yan T, Avila-Pacheco J, Plichta D, Aron A, Wang M, Jarmusch A, Hao F, Syrkin-Nikolau M, Vlamakis H, Ananthakrishnan AN, Boland BS, Hemperly A, Vande Casteele N, Gonzalez FJ, Clish C, Xavier R, Chu H, Baker ES, Patterson A, Knight R, Siegel D, Dorrestein PC. 2024. Reverse metabolomics for the discovery of chemical structures from humans. Nature 626(7998):419-426. doi:10.1038/s41586-023-06906-8 PMID:38052229

2022

• Bapat SP, Whitty C, Mowery CT, Liang Y, Yoo A, Jiang Z, Peters MC, Zhang L, Vogel I, Zhou C, Nguyen V, Li Z, Chang C, Zhu WS, Hastie AT, He H, Ren X, Qiu W, Gayer SG, Liu C, Choi EJ, Fassett M, Cohen JN, Sturgill JL, Alexander LE, Suh J, Liddle C, Atkins AR, Yu RT, Downes M, Liu S, Nikolajczyk BS, Lee I, Guttman-Yassky E, Ansel KM, Woodruff PG, Fahy JV, Sheppard D, Gallo RL, Ye CJ, Evans RM, Zheng Y, Marson A. 2022. Obesity alters pathology and treatment response in inflammatory disease. Nature 604:337-342. doi:10.1038/s41586-022-04536-0 PMID:35355021
• Gentry E, Collins S, Panitchpakdi M, Belda-Ferre P, Stewart AK, Wang M, Jarmusch A, Avila-Pacheco J, Plichta D, Aron A, Vlamakis H, Ananthakrishnan AN, Clish C, Xavier R, Baker ES, Patterson A, Knight R, Siegel D. 2022. Synthesis-based reverse metabolomics approach for the discovery of chemical structures from humans and animals. Nature PMID:38052229

2021

• Yoshihara E, O'Connor C, Gasser E, Wei Z, Oh TG, Tseng TW, Wang D, Cayabyab F, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. 2021. Immune-evasive human islet-like organoids ameliorate diabetes. Nature 590:doi:10.1038/s41586-020-03109-3 PMID:33469222

2020

• Quinn RA, Melnik A, Vrbanac AF, Fu T, Patras K, Christy M, Bodai Z, Belda-Ferre P, Tripathi A, Chung L, Downes M, Welch R, Quinn M, Humphrey G, Panitchpakdi M, Weldon K, Aksenov AA, da Silva R, Avila-Pacheco J, Clish C, Bae S, Mallick H, Franzosa E, Lloyd-Price J, Bussell R, Thron T, Nelson AT, Wang M, Leszczynski E, Vargas F, Gauglitz J, Meehan M, Gentry E, Arthur T, Komor A, Poulsen O, Boland BS, Chang JT, Sandborn W, Lim M, Garg N, Lumeng J, Xavier R, Kazmierczak B, Jain R, Egan M, Rhee K, Ferguson D, Raffatellu M, Vlamakis H, Haddad G, Siegel D, Huttenhower C, Mazmanian S, Evans RM, Nizet V, Knight R, Dorrestein PC. 2020. Global chemical effects of the microbiome include new bile-acid conjugations. Nature 579:123-129. doi:10.1038/s41586-020-2047-9 PMID:32103176

2019

• Bailey-Serres J, Parker JE, Ainsworth EA, Oldroyd GE, Schroeder JI. 2019. Genetic strategies for improving crop yields. Nature 575:109-118. doi:10.1038/s41586-019-1679-0 PMID:31695205 PMCID:PMC7024682
• Bersuker K, Hendricks JM, Li Z, Magtanong L, Ford B, Tang PH, Roberts MA, Tong B, Maimone T, Zoncu R, Bassik MC, Nomura DK, Dixon SJ, Olzmann J. 2019. The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature 575:688-692. doi:10.1038/s41586-019-1705-2 PMID:31634900 PMCID:PMC6883167
• Lim X. 2019. Tainted water: the scientists tracing thousands of fluorinated chemicals in our environment. Nature 566:26-29. doi:10.1038/d41586-019-00441-1 PMID:30728524

2018

• Que X, Hung M, Yeang C, Gonen A, Prohaska TA, Sun X, Diehl C, Maatta A, Gaddis DE, Bowden K, Pattison J, MacDonald JG, Yla-Herttuala S, Mellon PL, Hedrick CC, Ley K, Miller YI, Glass CK, Peterson KL, Binder CJ, Tsimikas S, Witztum JL. 2018. Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice. Nature 558:301. doi:10.1038/s41586-018-0198-8 PMID:29875409 PMCID:PMC6033669
• Rappaport SM. 2018. Redefining environmental exposure for disease etiology. Nature 4(30):doi:10.1038/s41540-018-0065-0 PMID:30181901 PMCID:PMC6119193
• Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin X, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M. 2018. New mitochondrial DNA synthesis enables NLRP3 inflammasome activation. Nature 560:198-203. doi:10.1038/s41586-018-0372-z PMID:30046112 PMCID:PMC6329306

2017

• Burgos-Barragan G, Wit N, Meiser J, Dingler FA, Pietzke M, Mulderrig L, Pontel LB, Rosado IV, Brewer TF, Cordell RL, Monks PS, Chang C, Vazquez A, Patel KJ. 2017. Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism. Nature 548:549-554. doi:10.1038/nature23481 PMID:28813411 PMCID:PMC5714256
• Shalapour S, Lin X, Bastian IN, Brain J, Burt AD, Aksenov AA, Vrbanac AF, Li W, Perkins A, Matsutani T, Zhong Z, Dhar D, Navas-Molina JA, Xu J, Loomba R, Downes M, Yu RT, Evans RM, Dorrestein PC, Knight R, Benner CW, Anstee QM, Karin M. 2017. Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature 551(7680):340-345. doi:10.1038/nature24302 PMID:29144460 PMCID:PMC5884449

2016

• Karin M, Clevers H. 2016. Reparative inflammation takes charge of tissue regeneration. Nature 529(7586):307-315. doi:10.1038/nature17039 PMID:26791721 PMCID:PMC5228603
• Wu TP, Wang T, Seetin MG, Lai Y, Zhu S, Lin K, Liu Y, Byrum SD, Mackintosh SG, Zhong M, Tackett A, Wang G, Hon LS, Fang G, Swenberg JA, Xiao AZ. 2016. DNA methylation on N(6)-adenine in mammalian embryonic stem cells. Nature 532(7599):329-333. doi:10.1038/nature17640 PMID:27027282 PMCID:PMC4977844

2015

• Bapat SP, Suh J, Fang S, Liu S, Zhang Y, Cheng A, Zhou C, Liang Y, Leblanc M, Liddle C, Atkins AR, Yu RT, Downes M, Evans RM, Zheng Y. 2015. Depletion of fat-resident Treg cells prevents age-associated insulin resistance. Nature 528(7580):137-141. doi:10.1038/nature16151 PMID:26580014 PMCID:PMC4670283
• Suh J, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin Y, Yu RT, Liddle C, Atkins AR, Olefsky J, Mohammadi M, Downes M, Evans RM. 2015. Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature 520(7547):388. doi:10.1038/nature14304 PMID:25739500 PMCID:PMC4184286

2014

• Engineer C, Ghassemian M, Anderson JC, Peck SC, Hu H, Schroeder JI. 2014. Carbonic anhydrases, EPF2 and a novel protease mediate CO2 control of stomatal development. Nature 513(7517):246-250. doi:10.1038/nature13452 PMID:25043023 PMCID:PMC4274335

2013

• Amemiya CT, Alfoldi J. 2013. The African coelacanth genome provides insights into tetrapod evolution. Nature 496:311–316. doi:10.1038/nature12027 PMID:23598338 PMCID:PMC3633110
• Schroeder JI, Delhaize E, Frommer WB, Guerinot ML, Harrison MJ, Herrera-Estrella L, Horie T, Kochian LV, Munns R, Nishizawa NK, Tsay Y, Sanders D. 2013. Using membrane transporters to improve crops for sustainable food production. Nature 497:60-66. doi:10.1038/nature11909 PMID:23636397 PMCID:PMC3954111
• van Geen AF, Bostick BC, Trang PK, Lan V, Mai N, Manh PD, Viet PH, Radloff KA, Aziz Z, Mey JL, Stahl MO, Harvey CF, Oates P, Weinman B, Stengel C, Frei F, Kipfer R, Berg M. 2013. Retardation of arsenic transport through a Pleistocene aquifer. Nature 501:204-207. doi:10.1038/nature12444 PMID:24025840 PMCID:PMC3772538

2010

• Atwell S, Huang YS, Vilhjalmsson BJ, Willems G, Horton M, Li Y, Meng D, Platt A, Tarone AM, Hu TT, Jiang R, Muliyati N, Zhang X, Amer M, Baxter I, Brachi B, Chory J, Dean C, Debieu M, de Meaux J, Ecker JR, Faure N, Kniskern JM, Jones JD, Michael T, Nemri A, Roux F, Salt DE, Tang C, Todesco M, Traw M, Weigel D, Marjoram P, Borevitz JO, Bergelson J, Nordborg M. 2010. Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature 465(7298):627-631. doi:10.1038/nature08800 PMID:20336072 PMCID:PMC3023908 (Completed with ARRA Funds)

2008

• VAHISALU T, KOLLIST H, Wang Y, Nishimura N, Chan W, Valerio G, LAMMINMÄKI A, BROSCHE M, DESIKAN R, Schroeder JI, KANGASJÄRVI J, MOLDAU H. 2008. SLAC1 is required for plant guard cell S-type anion channel function in stomatal signalling. Nature 452:487-491. PMID:18305484

2006

• Schroeder JI, Kuhn JM. 2006. Plant biology: abscisic acid in bloom. Nature 439(7074):277-278. doi:10.1038/439277a PMID:16421556

2004

• Hsu L, Park JM, Zhang K, Luo J, Maeda S, Kaufman RJ, Eckmann L, Guiney DG, Karin M. 2004. The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4. Nature 428(6980):341-345. PMID:15029200
• Sil AK, Maeda S, Sano Y, Roop DR, Karin M. 2004. Abstract IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis. Nature 428(6983):660-664. PMID:15071597

2002

• Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS. 2002. A central role for JNK in obesity and insulin resistance. Nature 420(6913):333-336. PMID:12447443

2001

• Schroeder JI, Kwak JM, Allen GJ. 2001. Guard cell abscisic acid signalling and engineering drought hardiness in plants. Nature 410:327-330. PMID:11268200
• Tang G, Minemoto Y, Dibling B, Purcell NH, Li Z, Karin M, Lin A. 2001. Inhibition of JNK activation by NF-kB target genes. Nature 414(6861):313-317. PMID:11713531

2000

• Pei Z, Murata Y, Benning G, Thomine S, Klusener B, Allen GJ, Grill E, Schroeder JI. 2000. Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells. Nature 406:731-734. PMID:10963598

1997

• Kennedy BP, Folt CL, Blum JD, Chamberlain CP. 1997. Natural isotope markers in salmon. Nature 387:766-767.
• Kennedy BP, Folt CL, Blum JD, Chamberlain CP. 1997. Tracing rearing tributaries of migrating Atlantic salmon (Salmo salar) using Sr isotopes. Nature 387:766.