Superfund Research Program

Cell Metabolism (impact factor: 27.287)

2022

• Gao H, Jin Z, Bandyopadhyay G, Rocha KC, Liu X, Zhao H, Zhang D, Jouihan H, Pourshahian S, Kisseleva T, Brenner DA, Ying W, Olefsky J. 2022. MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH. Cell Metab 34(7):978-990. doi:10.1016/j.cmet.2022.05.008 PMID:35700738 PMCID:PMC9262870
• Gao H, Jin Z, Bandyopadhyay G, Wang G, Zhang D, Rocha KC, Liu X, Zhao H, Kisseleva T, Brenner DA, Karin M, Ying W. 2022. Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis. Cell Metab 34(8):1201-1213. doi:10.1016/j.cmet.2022.07.006 PMID:35921818 PMCID:PMC9365100
• Huang DQ, Singal AG, Kono Y, Tan DJ, El-Serag HB, Loomba R. 2022. Changing global epidemiology of liver cancer from 2010 to 2019: NASH is the fastest growing cause of liver cancer. Cell Metab 34(7):969-977. doi:10.1016/j.cmet.2022.05.003 PMID:35793659
• Kim J, Wang LQ, Sladky VC, Oh TG, Liu J, Trinh K, Eichin F, Downes M, Hosseini M, Jacotot ED, Evans RM, Villunger A, Karin M. 2022. PIDDosome-SCAP crosstalk controls high-fructose-diet-dependent transition from simple steatosis to steatohepatitis. Cell Metab 34(10):1548-1560. doi:10.1016/j.cmet.2022.08.005 PMID:36041455 PMCID:PMC9547947
• Liu Y, Meric G, Havulinna AS, Teo SM, Aberg F, Ruuskanen MO, Sanders JG, Zhu Q, Tripathi A, Verspoor K, Cheng S, Jain M, Jousilahti P, Vazquez-Baeza Y, Loomba R, Lahti L, Niiranen TJ, Salomaa VV, Knight R, Inouye M. 2022. Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting. Cell Metab 34(5):719-730. doi:10.1016/j.cmet.2022.03.002 PMID:35354069 PMCID:PMC9097589
• Sancar G, Liu S, Gasser E, Alvarez JG, Moutos CP, Kim K, van Zutphen T, Wang Y, Huddy T, Ross B, Dai Y, Zepeda D, Collins B, Tilley E, Kolar MJ, Yu RT, Atkins AR, van Dijk TH, Saghatelian A, Jonker JW, Downes M, Evans RM. 2022. FGF1 and insulin control lipolysis by convergent pathways. Cell Metab 34(1):171-183. doi:10.1016/j.cmet.2021.12.004 PMID:34986332 PMCID:PMC886306

2021

• Febbraio MA, Karin M. 2021. Sweet death: Fructose as a metabolic toxin that targets the gut-liver axis. Cell Metab 33(12):doi:10.1016/j.cmet.2021.09.004 PMID:34619076 PMCID:PMC8665123
• Sharpton SR, Schnabl B, Knight R, Loomba R. 2021. Current concepts, opportunities, and challenges of gut microbiome-based personalized medicine in nonalcoholic fatty liver disease. Cell Metab 33(1):21-32. doi:10.1016/j.cmet.2020.11.010 PMID:33296678 PMCID:PMC8414992

2020

• Carter CS, Huang SC, Searby CC, Cassaidy B, Miller MJ, Grzesik WJ, Piorczynski TB, Pak TK, Walsh SA, Acevedo M, Zhang Q, Mapuskar KA, Milne GL, Hinton AO, Guo D, Weiss R, Bradberry K, Taylor EB, Rauckhorst AJ, Dick DW, Akurathi V, Falls-Hubert KC, Wagner BA, Carter WA, Wang K, Norris AW, Rahmouni K, Buettner GR, Hansen JM, Spitz DR, Abel ED, Sheffield VC. 2020. Exposure to static magnetic and electric fields treats type 2 diabetes. Cell Metab 32:561-574. doi:10.1016/j.cmet.2020.09.012 PMID:33027675
• Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba E, Bettencourt R, Richards L, Raffatellu M, Dorrestein PC, Yu RT, Atkins AR, Huan T, Brenner DA, Sirlin C, Knight R, Downes M, Evans RM, Loomba R. 2020. A universal gut-microbiome-derived signature predicts cirrhosis. Cell Metab 32:doi:10.1016/j.cmet.2020.10.015 PMID:33147487 PMCID:PMC7891106 (accepted for publication)
• Sun X, Seidman J, Zhao P, Troutman T, Spann N, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida J, Kisseleva T, Brenner DA, Downes M, Evans RM, Saltiel AR, Tsimikas S, Glass CK, Witztum JL. 2020. Neutralization of oxidized phospholipids ameliorates non-alcoholic steatohepatitis. Cell Metab 31(1):189-206. doi:10.1016/j.cmet.2019.10.014 PMID:31761566 PMCID:PMC7028360

2019

• Febbraio MA, Reibe S, Shalapour S, Ooi GJ, Watt MJ, Karin M. 2019. Preclinical models for studying NASH-driven HCC: How useful are they?. Cell Metab 29:18-26. doi:10.1016/j.cmet.2018.10.012 PMID:30449681 PMCID:PMC6326872
• Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, Murphy AN, Hoffman HM, Tiziani S, Guma M, Karin M. 2019. Choline Uptake and metabolism modulate macrophage IL-1 beta and IL-18 production. Cell Metab 29:1350. doi:10.1016/j.cmet.2019.03.011 PMID:30982734 PMCID:PMC6675591

2017

• Fan W, Evans RM. 2017. Exercise mimetics: impact on health and performance. Cell Metab 25(2):242-247. doi:10.1016/j.cmet.2016.10.022 PMID:27889389
• Fan W, Waizenegger W, Lin CS, Sorrentino V, He M, Wall CE, Li H, Liddle C, Yu RT, Atkins AR, Auwerx J, Downes M, Evans RM. 2017. PPARdelta promotes running endurance by preserving glucose. Cell Metab 25:1186-1193.e4. doi:10.1016/j.cmet.2017.04.006 PMID:28467934 PMCID:PMC549297
• Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, Chen C, Brenner DA, Biggs W, Yooseph S, Venter JC, Nelson KE. 2017. Gut microbiome-based metagenomic signature for non-invasive detection of advanced fibrosis in human nonalcoholic fatty liver disease. Cell Metab 25(5):1054-1062.e5. doi:10.1016/j.cmet.2017.04.001 PMID:28467925 PMCID:PMC550273

2016

• Yoshihara E, Wei Z, Lin CS, Fang S, Ahmadian M, Kida Y, Tseng TW, Dai Y, Yu RT, Liddle C, Atkins AR, Downes M, Evans RM. 2016. ERRγ is required for the metabolic maturation of therapeutically functional glucose-responsive β cells. Cell Metab 23(4):622-634. doi:10.1016/j.cmet.2016.03.005 PMID:27076077 PMCID:PMC4832237

2014

• Dhar D, Seki E, Karin M. 2014. NCOA5, IL-6, type 2 diabetes, and HCC: the deadly quartet. Cell Metab 19(1):6-7. doi:10.1016/j.cmet.2013.12.010 PMID:24411937 PMCID:PMC3947913
• Umemura A, Park E, Taniguchi K, Lee J, Shalapour S, Valasek MA, Aghajan M, Nakagawa H, Seki E, Hall MN, Karin M. 2014. Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell Metab 20(1):133-144. doi:10.1016/j.cmet.2014.05.001 PMID:24910242 PMCID:PMC4079758

2013

• Lee J, Budanov AV, Karin M. 2013. Sestrins orchestrate cellular metabolism to attenuate aging. Cell Metab 18(6):792-801. doi:10.1016/j.cmet.2013.08.018 PMID:24055102 PMCID:PMC3858445

2012

• Lee J, Budanov AV, Talukdar S, Park E, Park H, Park H, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M. 2012. Maintenance of metabolic homeostasis by Sestrin 2 and Sestrin 3. Cell Metab 16(3):311-321. doi:10.1016/j.cmet.2012.08.004 PMID:22958918 PMCID:PMC3687365

2010

• Kim B, Turski ML, Nose Y, Casad M, Rockman HA, Thiele D. 2010. Cardiac copper deficiency activates a systemic signaling mechanism that communicates with the copper acquisition and storage organs. Cell Metab 11(5):353-63. doi:10.1016/j.cmet.2010.04.003 PMID:20444417 PMCID:PMC2901851

2008

• Aronova S, Wedaman K, Aronov PA, Fontes K, Ramos K, Hammock BD, Powers T. 2008. Regulation of ceramide biosynthesis by TOR complex 2. Cell Metab 7(2):148-158. doi:10.1016/j.cmet.2007.11.015 PMID:18249174 PMCID:PMC3882310