An official website of the United States government
The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.
The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Internet Explorer is no longer a supported browser.
This website may not display properly with Internet Explorer. For the best experience, please use a more recent browser such as the latest versions of Google Chrome, Microsoft Edge, and/or Mozilla Firefox. Thank you.
COVID-19 is an emerging, rapidly evolving situation.
Isobe Y, Okumura M, McGregor LM, Brittain SM, Jones MD, Liang X, White R, Forrester W, McKenna JM, Tallarico JA, Schirle M, Maimone T, Nomura DK. 2020. Manumycin polyketides act as molecular glues between UBR7 and P53. Nat Chem Biol 16:1189-1198. doi:10.1038/s41589-020-0557-2PMID:32572277PMCID:PMC7572527
2019
Black WB, Zhang L, Mak WS, Maxel S, Cui Y, King E, Fong B, Sanchez Martinez A, Siegel JB, Li H. 2019. Engineering a nicotinamide mononucleotide redox cofactor system for biocatalysis. Nat Chem Biol 16:87-94. doi:10.1038/s41589-019-0402-7PMID:31768035
2018
Yan J, Bi M, Bourdon AK, Farmer AT, Wang P, Molenda O, Quaile AT, Jiang N, Yang Y, Yin Y, Şimşir B, Campagna SR, Edwards EA, Loeffler FE. 2018. Purinyl-cobamide is a native prosthetic group of reductive dehalogenases. Nat Chem Biol 14:8-14. doi:10.1038/nchembio.2512PMID:29106396