An official website of the United States government
The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
National Institute of Environmental Health Sciences
Use this QR code to view the newest version of this document
Your Environment. Your Health.
Details for High Impact Journal
Superfund Research Program
Cancer Research (impact factor: 12.701)
2024
Ahn S, Park J, Grimm SL, Piyarathna DW, Samanta T, Putluri V, Mezquita D, Fuqua SA, Putluri N, Coarfa C, Kaipparettu B. 2024. Metabolomic rewiring promotes endocrine therapy resistance in breast cancer. Cancer Res 84(2):291-304. doi:10.1158/0008-5472.Can-23-0184PMID:37906431PMCID:10842725
2021
Kohale I, Burgenske DM, Mladek AC, Bakken KK, Kuang J, Boughey J, Wang L, Carter JM, Haura EB, Goetz MP, Sarkaria JN, White FM. 2021. Quantitative analysis of tyrosine phosphorylation from FFPE tissues reveals patient-specific signaling networks. Cancer Res doi:10.1158/0008-5472.CAN-21-0214PMID:34016623
Stopfer LE, Flower CT, Gajadhar AS, Patel B, Gallien S, Lopez-Ferrer D, White FM. 2021. High-density, targeted monitoring of tyrosine phosphorylation reveals activated signaling networks in human tumors. Cancer Res 81:2495-2509. doi:10.1158/0008-5472.CAN-20-3804PMID:33509940PMCID:PMC8137532
2020
Lenkiewicz E, Malasi S, Hogenson TL, Flores LF, Barham W, Phillips WJ, Roesler AS, Chambers KR, Rajbhandari N, Hayashi A, Antal CE, Downes M, Grandgenett PM, Hollingsworth MA, Cridebring D, Xiong Y, Lee J, Ye Z, Yan H, Hernandez MC, Leiting JL, Evans RM, Ordog T, Truty MJ, Borad MJ, Reya T, Von Hoff DD, Fernandez-Zapico ME, Barrett MT. 2020. Genomic and epigenomic landscaping defines new therapeutic targets for adenosquamous carcinoma of the pancreas. Cancer Res 80:4324-4334. doi:10.1158/0008-5472.CAN-20-0078PMID:32928922
2019
Grigoryan H, Schiffman C, Gunter MJ, Naccarati A, Polidoro S, Dagnino S, Dudoit S, Vineis P, Rappaport SM. 2019. Cys34 adductomics links colorectal cancer with the gut microbiota and redox biology. Cancer Res 79(23):6024-6031. doi:10.1158/0008-5472.CAN-19-1529PMID:31641032PMCID:PMC6891211
Wang W, Yang J, Edin ML, Wang Y, Luo Y, Wan D, Yang H, Song C, Xue W, Sanidad KZ, Song M, Bisbee HA, Bradbury JA, Nan G, Zhang J, Shih P, Sing K, Lee S, Minter LM, Kim D, Xiao H, Liu J, Hammock BD, Zeldin DC, Zhang G. 2019. Targeted Metabolomics identifies the cytochrome P450 monooxygenase eicosanoid pathway as a novel therapeutic target of colon tumorigenesis. Cancer Res 79:1822-1830. doi:10.1158/0008-5472.CAN-18-3221PMID:30803995PMCID:PMC6467714
2016
Kadariya Y, Cheung M, Xu J, Pei J, Sementino E, Menges CW, Cai KQ, Rauscher FJ, Klein-Szanto AJ, Testa JR. 2016. Bap1 is a bona fide tumor suppressor: genetic evidence from mouse models carrying heterozygous germline Bap1 mutations. Cancer Res 76(9):2836-2844. doi:10.1158/0008-5472.CAN-15-3371PMID:26896281PMCID:PMC4873414
Lai Y, Yu R, Hartwell HJ, Moeller BC, Bodnar WM, Swenberg JA. 2016. Measurement of endogenous versus exogenous formaldehyde-induced DNA-protein crosslinks in animal tissues by stable isotope labeling and ultrasensitive mass spectrometry. Cancer Res 76(9):2652-2661. doi:10.1158/0008-5472.CAN-15-2527PMID:26984759PMCID:PMC4879886
Ohar J, Cheung M, Talarchek J, Howard S, Howard T, Hesdorffer M, Peng H, Rauscher FJ, Testa JR. 2016. Germline BAP1 mutational landscape of asbestos-exposed malignant mesothelioma patients with family history of cancer. Cancer Res 76(2):206-215. doi:10.1158/0008-5472.CAN-15-0295PMID:26719535PMCID:PMC4715907
2013
Rawal M, Schroeder SR, Wagner BA, Cushing CM, Welsh JL, Button AM, Du J, Sibenaller ZA, Buettner GR, Cullen JJ. 2013. Manganoporphyrins increase ascorbate-induced cytotoxicity by enhancing H2O2 generation. Cancer Res 73(16):5232-5241. doi:10.1158/0008-5472.can-13-0470PMID:23764544PMCID:PMC3745518
Sakurai T, Kudo M, Umemura A, He G, Elsharkawy AM, Seki E, Karin M. 2013. p38αlpha inhibits liver fibrogenesis and consequent hepatocarcinogenesis by curtailing accumulation of reactive oxygen species. Cancer Res 73(1):215-224. doi:10.1158/0008-5472.CAN-12-1602PMID:23271722PMCID:PMC3605785
2012
Sarsour EH, Kalen AL, Xiao Z, Veenstra TD, Chaudhuri L, Venkataraman S, Reigan P, Buettner GR, Goswami PC. 2012. Manganese superoxide dismutase regulates a metabolic switch during the Mammalian Cell Cycle. Cancer Res 72:3807-3816. doi:10.1158/0008-5472.CAN-11-1063PMID:22710435PMCID:PMC3429130
2010
Fei DL, Li H, Kozul-Horvath CD, Black KE, Singh S, Gosse JA, DiRenzo J, Martin KA, Wang B, Hamilton JW, Karagas MR, Robbins DJ. 2010. Activation of Hedgehog signaling by the environmental toxicant arsenic may contribute to the etiology of arsenic-induced tumors. Cancer Res 70(5):1981-1988. doi:10.1158/0008-5472.CAN-09-2898PMID:20179202PMCID:PMC2831120
Zhang D, Li J, Costa M, Gao J, Huang C. 2010. JNK1 mediates degradation HIF-1alpha by a VHL-independent mechanism that involves the chaperones Hsp90/Hsp70. Cancer Res 70(2):813-823. doi:10.1158/0008-5472.CAN-09-0448PMID:20068160PMCID:PMC2939838 (Completed with ARRA Funds)
2009
Ivanov VN, Zhou HZ, Partridge MA, Hei TK. 2009. Inhibition of ataxia telangiectasia mutated kinase activity enhances TRAIL-mediated apoptosis in human melanoma cells. Cancer Res 69(8):3510-3519. doi:10.1158/0008-5472.CAN-08-3883PMID:19351839PMCID:PMC4070218
Stern MC, Lin J, Figueroa JD, Kelsey KT, Kiltie AE, Yuan J, Matullo G, Fletcher T, Benhamou S, Taylor JA, Placidi D, Zhang Z, Steineck G, Rothman N, Kogevinas M, Silverman DT, Malats N, Chanock SJ, Wu X, Karagas MR, Andrew AS, Nelson HH, Bishop DT, Sak S, Choudhury A, Barrett JH, Elliot F, Corral R, Joshi AD, Gago-Dominguez M, Cortessis VK, Gao Y, Xiang Y, Vineis P, Sacerdote C, Guarrera S, Polidoro S, Allione A, Gurzau ES, Koppova K, Kumar R, Rudnai P, Porru S, Carta A, Campagna M, Arici C, Park S, Garcia-Closas M. 2009. Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer. Cancer Res 69(17):6857-6864. doi:10.1158/0008-5472.CAN-09-1091PMID:19706757PMCID:PMC2782435
2008
Wiemels JL, Hofmann J, Kang M, Selzer R, Green R, Zhou M, Zhong S, Zhang L, Smith MT, Marsit CJ, Loh ML, Buffler PA, Yeh R. 2008. Chromosome 12p deletions in TEL-AML1 childhood acute lymphoblastic leukemia are associated with retrotransposon elements and occur postnatally. Cancer Res 68(23):9935-9944. doi:10.1158/0008-5472.CAN-08-2139PMID:19047175PMCID:PMC2597307
2007
Partridge MA, Huang SX, Hernandez-Rosa E, Davidson MM, Hei TK. 2007. Arsenic induced mitochondrial DNA damage and alteredmitochondrial oxidative function: implication for genotoxic mechanismsin mammalian cells. Cancer Res 67(11):5239-5247.
Pietruska JR, Kane AB. 2007. SV40 oncoproteins enhance asbestos-induced dna double-strand breaks and abrogate senescence in murine mesothelial cells. Cancer Res 67:3637-45. PMID:17440075
Ridpath JR, Nakamura J, Tano K, Luke AM, Sonoda E, Arakawa H, Buerstedde J, Gillespie DA, Sale JE, Yamazoe M, Bishop DK, Takata M, Takeda S, Watanabe M, Swenberg JA. 2007. Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde. Cancer Res 67(23):11117-11122. doi:10.1158/0008-5472.CAN-07-3028PMID:18056434
Vladimir I, Zhou HZ, Hei TK. 2007. Gamma-irradiation or alpha-particle exposure sensitize human melanoma cells to TRAIL-mediated apoptosis through upregulation of TRAIL R2/DR5 expression and translocation to the cell surface. Cancer Res 67:5397-5407.
Vladimir I, Zhou HZ, Hei TK. 2007. Sequential treatment by ionizing radiation and sodium arsenite dramatically accelerates TRAIL-mediated apoptosis of human melanoma cells. Cancer Res 67(11):5397-5407. PMID:17545621
2006
Abdelrahim M, Ariazi E, Kim K, Khan S, Barhoumi R, Burghardt RC, Liu S, Hill DS, Finnell RH, Wlodarczyk BJ, Jordan VC, Safe SH. 2006. 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Res 66(4):2459-2467. doi:10.1158/0008-5472.CAN-05-3132PMID:16489053
Marsit CJ, Eddy K, Kelsey KT. 2006. MicroRNA responses to cellular stress. Cancer Res 66(22):10843-10848. PMID:17108120
Marsit CJ, Houseman EA, Eddy K, Bueno R, Sugarbaker DJ, Nelson HH, Karagas MR, Kelsey KT, Christensen BC. 2006. Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors. Cancer Res 66(21):10621-9. PMID:17079487
Pachkowski BF, Winkel S, Kubota Y, Swenberg JA, Millikan RC, Nakamura J. 2006. XRCC1 genotype and breast cancer: functional studies and epidemiologic data show interactions between XRCC1 codon 280 His and smoking. Cancer Res 66(5):2860-2868. doi:10.1158/0008-5472.CAN-05-3388PMID:16510609
2005
Canter JA, Kallianpur AR, Parl FF, Millikan RC. 2005. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res 65(17):8028-8033. doi:10.1158/0008-5472.CAN-05-3774PMID:16140977
Lan Q, Zhang L, Shen M, Smith MT, Li G, Vermeulen R, Rappaport SM, Forrest MS, Hayes RB, Linet MS, Dosemeci M, Alter BP, Weinberg RS, Yin S, Yeager M, Welch R, Waidyanatha S, Kim S, Chanock SJ, Rothman N. 2005. Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene. Cancer Res 65(20):9574-9581. doi:10.1158/0008-5472.CAN-05-1419PMID:16230423
Liu S, Davidson MM, Tang X, Walker WF, Athar M, Ivanov VN, Hei TK. 2005. Mitochondrial damage mediates genotoxicity of arsenic in mammalian cells. Cancer Res 65(8):3236-3242. PMID:15833855
Marsit CJ, Karagas MR, Andrew AS, Liu M, Danaee H, Schned AR, Nelson HH, Kelsey KT. 2005. Epigenetic inactivation of SFRP genes and TP53 alteration act jointly as markers of invasive bladder cancer. Cancer Res 65(16):7081-7085. PMID:16103055
2004
Li J, Davidson G, Huang Y, Jiang B, Shi X, Costa M, Huang C. 2004. Nickel compounds act through phosphatidylinositol-3-kinase/Akt-dependent, p70(S6k)-independent pathway to induce hypoxia inducible factor transactivation and Cap43 expression in mouse epidermal Cl41 cells. Cancer Res 64(1):94-101. PMID:14729612
Rusyn I, Asakura S, Pachkowski BF, Bradford BU, Denissenko MF, Peters JM, Holland SM, Reddy JK, Cunningham ML, Swenberg JA. 2004. Expression of base excision DNA repair genes is a sensitive biomarker for in vivo detection of chemical-induced chronic oxidative stress: Identification of the molecular source of radicals responsible for DNA damage by peroxisome proliferators. Cancer Res 64(3):1050-1057. PMID:14871837
Wiemels JL, Wiencke JK, Patoka J, Moghadassi M, Chew T, McMillan A, Miike R, Barger G, Wrensch MR. 2004. Reduced immunoglobulin E and allergy among adults with glioma compared with controls. Cancer Res 64(22):8468-8473. PMID:15548720
Yoon J, Besaratinia A, Feng Z, Tang M, Amin S, Luch A, Pfeifer GP. 2004. DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells. Cancer Res 64(20):7321-7328. doi:10.1158/0008-5472.CAN-04-1094PMID:15492252
Zheng S, Ma X, Zhang L, Gunn L, Smith MT, Wiemels JL, Leung K, Buffler PA, Wiencke JK. 2004. Hypermethylation of the 5 ' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia. Cancer Res 64(6):2000-2006. PMID:15026336
2003
Chen F, Castranova V, Li Z, Karin M, Shi X. 2003. Inhibitor of nuclear factor kappa B kinase deficiency enhances oxidative stress and prolongs c-jun NH2-terminal kinase activation induced by arsenic. Cancer Res 63(22):7689-7693. PMID:14633691
Martin EA, Brown K, Gaskell M, Al-Azzawi F, Garner RC, Boocock DJ, Mattock E, Pring DW, Dingley KH, Turteltaub KW, Smith LL, White IN. 2003. Tamoxifen DNA damage detected in human endometrium using accelerator mass spectrometry. Cancer Res 63(23):8461-8465. PMID:14679010
Qin C, Burghardt RC, Smith RL, Wormke M, Stewart J, Safe SH. 2003. Peroxisome proliferator-activated receptor gamma agonists induce proteasome-dependent degradation of cyclin D1 and estrogen receptor alpha in MCF-7 breast cancer cells. Cancer Res 63(5):958-964. PMID:12615709
Salnikow K, Davidson T, Zhang Q, Chen L, Su W, Costa M. 2003. The involvement of hypoxia-inducible transcription factor-1-dependent pathway in nickel carcinogenesis. Cancer Res 63(13):3524-3530. PMID:12839937
2002
Li X, Eckard J, Shah R, Malluck C, Frenkel K. 2002. Interleukin-1alpha up-regulation in vivo by a potent carcinogen 7,12-dimethylbenz(a)anthracene (DMBA) and control of DMBA-induced inflammatory responses. Cancer Res 62(2):417-423. PMID:11809690
Morinello EJ, Ham AL, Ranasinghe A, Nakamura J, Upton PB, Swenberg JA. 2002. Molecular dosimetry and repair of N2,3-ethenoguanine in rats exposed to vinyl chloride. Cancer Res 62:5189-5195. PMID:12234983
Morinello EJ, Koc H, Ranasinghe A, Swenberg JA. 2002. Differential induction of N2,3-ethenoguanine in rat brain and liver after exposure to vinyl chloride. Cancer Res 62:5183-5188.
Rappaport SM, Waidyanatha S, Qu Q, Shore R, Jin X, Cohen B, Chen L, Melikian AA, Li G, Yin S, Yan H, Xu B, Mu R, Li Y, Zhang X, Li K. 2002. Albumin adducts of benzene oxide and 1,4-benzoquinone as measures of human benzene metabolism. Cancer Res 62(5):1330-1337. PMID:11888901
2001
Chen P, Aldape K, Wiencke JK, Kelsey KT, Miike R, Davis RL, Liu J, Kesler-Diaz A, Takahashi M, Wrensch MR. 2001. Ethnicity delineates different genetic pathways in malignant glioma. Cancer Res 61:3949-3954. PMID:11358811
Hirao T, Nelson HH, Devi-Ashok T, Wain JC, Mark EJ, Christiani DC, Wiencke JK, Kelsey KT. 2001. Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancer. Cancer Res 61(2):612-615. PMID:11212258
Huang C, Li J, Costa M, Zhang Z, Leonard SS, Castranova V, Vallyathan V, Ju G, Shi X. 2001. Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide. Cancer Res 61:8051-8057. PMID:11719426
Ou YC, Conolly RB, Thomas RS, Xu Y, Andersen ME, Chubb LS, Pitot HC, Yang RH. 2001. A clonal growth model: time-course simulations of liver foci growth following penta- or hexachlorobenzene treatment in a medium-term bioassay. Cancer Res 61(5):1879-1889. PMID:11280742
1999
Nakamura J, Swenberg JA. 1999. Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues. Cancer Res 59(11):2522-2526. PMID:10363965
Nelson HH, Christiani DC, Wiencke JK, Mark EJ, Wain JC, Kelsey KT. 1999. K-ras mutation and occupational asbestos exposure in lung adenocarcinoma: asbestos-related cancer without asbestosis. Cancer Res 59:4570-4573. PMID:10493509
1998
Cistulli CA, Kaufmann WK. 1998. P53-dependent signaling sustains DNA replication and enhances clonogenic survival in 254 nm ultraviolet-irradiated human fibroblasts. Cancer Res 58:1993-2002. PMID:9581844
Coller HA, Khrapko K, Torres A, Frampton MW, Utell MJ, Thilly WG. 1998. Mutational spectra of a 100-base pair mitochondrial DNA target sequence in bronchial epithelial cells: a comparison of smoking and nonsmoking twins. Cancer Res 58(6):1268-1277. PMID:9515815
Marcelino LA, Andre PC, Khrapko K, Coller HA, Griffith J, Thilly WG. 1998. Chemically induced mutations in mitochondrial DNA of human cells: Mutational spectrum of N-Methyl-N'-nitro-N-nitrosoguanidine. Cancer Res 58:2857-2862. PMID:9661902
Nakamura J, Walker V, Upton PB, Chiang S, Kow YW, Swenberg JA. 1998. Highly sensitive apurinic/apyrimidinic site assay can detect spontaneous and chemically induced depurination under physiological conditions. Cancer Res 58(2):222-225. PMID:9443396
Nelson HH, Wiencke JK, Gunn L, Wain JC, Christiani DC, Kelsey KT. 1998. Chromosome 3p14 alterations in lung cancer: evidence that FHIT exon deletion is a target of tobacco carcinogens and asbestos. Cancer Res 58(9):1804-1807. PMID:9581816
Smith MT, Zhang L, Wang Y, Hayes RB, Li G, Wiemels JL, Dosemeci M, Holland NT, Xi L, Kolachana P, Yin S, Rothman N. 1998. Increased translocations and aneusomy in chromosomes 8 and 21 among workers exposed to benzene. Cancer Res 58(10):2176-2181. PMID:9605763
Warren AJ, Maccubbin AE, Hamilton JW. 1998. Detection of mitomycin C-DNA adducts in vivo by 32P-postlabeling: Time course for formation and removal of adducts and biochemical modulation. Cancer Res 58:453-461. PMID:9458089
1997
Barbin A, Froment O, Boivin S, Marion M, Belpoggi F, Maltoni C, Montesano R. 1997. P53 Gene mutation pattern in rat liver tumors induced by vinyl chloride. Cancer Res 57(9):1695-1698. PMID:9135010
Rothman N, Smith MT, Hayes RB, Traver RD, Hoener B, Campleman S, Li G, Dosemeci M, Linet MS, Zhang L, Xi L, Wacholder S, Lu W, Meyer KB, Titenko-Holland N, Stewart JT, Yin S, Ross D. 1997. Benzene poisoning, a risk factor for hematologic malignancy, is associated with the NQ01 609C->T mutation and rapid fractional excretion of chlorzoxazone. Cancer Res 57(14):2839-2842. PMID:9230185
1996
Malins DC, Polissar NL, Garner MM, Gunselman SJ. 1996. Mutagenic DNA base modifications are correlated with lesions in nonneoplastic hepatic tissue of the English sole carcinogenesis model. Cancer Res 56(24):5563-5565. PMID:8971153
1995
Wiencke JK, Kelsey KT, Varkonyi A, Semey K, Wain JC, Mark EJ, Christiani DC. 1995. Correlation of DNA adducts in blood mononuclear cells with tobacco carcinogen-induced damage in human lung. Cancer Res 55(21):4910-4914. PMID:7585529
