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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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A new strategy to generate nanobodies for the coumaphos based on the synthesized nanobody libraries. | Fang, Ruyu; Li, Yingxue; Liu, Fei; Liang, Yifan; Wang, Yu; Zhong, Guohua; Xu, Zhenlin; Hammoc ... | P42ES004699, R35ES030443 | Food Chem (2024 Oct 15) | 38833869 | 2024 |
A novel sustainable immunoassay for sensitive detection of atrazine based on the anti-idiotypic nano ... | Zhao, Jing; Li, Peipei; Abd El-Aty, A M; Xu, Lingyuan; Lei, Xingmei; Gao, Song; Li, Jia; Zhao ... | P42ES004699, R35ES030443 | Chem Eng J (2024 Jul 01) | 38882000 | 2024 |
Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Induced Carcinogenesis and Tumorigenesis by Ome ... | Xia, Guobin; Zhou, Guodong; Jiang, Weiwu; Chu, Chun; Wang, Lihua; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Int J Mol Sci (2024 Mar 28) | 38612589 | 2024 |
Biosynthesis of magnetosome-nanobody complex in Magnetospirillum gryphiswaldense MSR-1 and a magneto ... | Wu, Sha; Tian, Jiesheng; Xue, Xianle; Ma, Fengfei; Li, Qing X; Morisseau, Christophe; Hammock, ... | P42ES004699, R35ES030443 | Anal Bioanal Chem (2024 Jan) | 37934249 | 2024 |
Competitive ratiometric fluorescent lateral flow immunoassay based on dual emission signal for sensi ... | Fang, Xuechen; Liu, Tingting; Xue, Chang; Xue, Guangjian; Wu, Mengyun; Liu, Pengyan; Hammock, ... | P42ES004699, R35ES030443 | Food Chem (2024 Feb 01) | 37678117 | 2024 |
Design and Synthesis of Dual-Targeting Inhibitors of sEH and HDAC6 for the Treatment of Neuropathic ... | Chen, Yuanguang; Sun, Jianwen; Tong, Hua; Wang, Jieru; Cao, Ruolin; Xu, Huashen; Chen, Lu; Mo ... | P42ES004699, R35ES030443 | J Med Chem (2024 Feb 08) | 38236416 | 2024 |
Design and Synthesis of sEH/HDAC6 Dual-Targeting Inhibitors for the Treatment of Inflammatory Pain. | Xu, Huashen; Chen, Yuanguang; Tong, Hua; Chen, Lu; Morisseau, Christophe; Zhou, Zijian; Zhuang ... | P42ES004699, R35ES030443 | J Med Chem (2024 Aug 08) | 39033411 | 2024 |
Development and Application of a Multidimensional Database for the Detection of Quaternary Ammonium ... | Nguyen, Ryan; Seguin, Ryan P; Ross, Dylan H; Chen, Pengyu; Richardson, Sean; Liem, Jennifer; L ... | R01ES031927, T32ES007032 | Environ Sci Technol (2024 Apr 09) | 38534032 | 2024 |
Development of a sensitive direct competitive chemiluminescent enzyme immunoassay for gentamicin bas ... | Deng, Weijie; Wang, Dan; Dai, Peng; Hong, Yanping; Xiong, Jianhua; Duan, Luying; Lu, Ruimin; ... | P42ES004699, R35ES030443 | Microchem J (2024 Feb) | 38283367 | 2024 |
Development of an immunoassay based on a specific antibody for the detection of diphenyl ether herbi ... | Gao, Qingqing; Chen, Lai; An, Zexiu; Wang, Yasen; Yang, Dongchen; Wang, Zhengzhong; Kang, Jia ... | P42ES004699, R35ES030443 | Sci Total Environ (2024 Mar 01) | 38190900 | 2024 |
Eicosanoid profiles in an arthritis model: Effects of a soluble epoxide hydrolase inhibitor. | Trindade-da-Silva, Carlos Antonio; Yang, Jun; Fonseca, Flavia; Pham, Hoang; Napimoga, Marcelo H ... | P42ES004699, R35ES030443 | Biochim Biophys Acta Mol Cell Biol Lipids (2024 Mar) | 37984607 | 2024 |
Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase. | Kelly, Abigail G; Wang, Weicang; Rothenberger, Eva; Yang, Jun; Gilligan, Molly M; Kipper, Fran ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2024 Feb 13) | 38330013 | 2024 |
Establishment of an indirect competitive immunoassay for the detection of dicamba based on a highly ... | Wang, Yasen; Zhou, Hui; Fu, Yining; Wang, Zhengzhong; Gao, Qingqing; Yang, Dongchen; Kang, Ji ... | P42ES004699, R35ES030443 | Sci Total Environ (2024 Mar 20) | 38296098 | 2024 |
Generation of a highly specific recombinant full-length antibody for detecting ethirimol in fruit an ... | Lei, Xingmei; Li, Peipei; Abd El-Aty, A M; Zhao, Jing; Xu, Lingyuan; Gao, Song; Li, Jia; Zhao ... | P42ES004699, R35ES030443 | J Hazard Mater (2024 May 05) | 38513441 | 2024 |
Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic ... | Panigrahy, Dipak; Kelly, Abigail G; Wang, Weicang; Yang, Jun; Hwang, Sung Hee; Gillespie, Mich ... | P42ES004699, R35ES030443 | bioRxiv (2024 Feb 19) | 38463975 | 2024 |
Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathoge ... | Hossain Hrithik, Md Tafim; Shahmohammadi, Niayesh; Jin, Gahyeon; Lee, Dong-Hee; Singh, Nalin; V ... | R35ES030443 | Insect Biochem Mol Biol (2024 May) | 38494144 | 2024 |
Interaction and Transport of Benzalkonium Chlorides by the Organic Cation and Multidrug and Toxin Ex ... | Vieira, Letícia Salvador; Seguin, Ryan P; Xu, Libin; Wang, Joanne | R01ES031927 | Drug Metab Dispos (2024 Mar 13) | 38307853 | 2024 |
Interaction of CYP3A4 with the inhibitor cobicistat: Structural and mechanistic insights and compari ... | Sevrioukova, Irina F | R01ES025767 | Arch Biochem Biophys (2024 Aug) | 38909836 | 2024 |
Metabolomic Effects of Folic Acid Supplementation in Adults: Evidence from the FACT Trial. | Martinez-Morata, Irene; Wu, Haotian; Galvez-Fernandez, Marta; Ilievski, Vesna; Bottiglieri, Teo ... | R01ES030945, R01ES030945, R35ES028379 | J Nutr (2024 Feb) | 38092151 | 2024 |
Modulating the sEH/EETs Axis Restrains Specialized Proresolving Mediator Impairment and Regulates T ... | Abdalla, Henrique B; Puhl, Luciano; Rivas, Carla Alvarez; Wu, Yu-Chiao; Rojas, Paola; Trindade- ... | P42ES004699, R35ES030443 | J Immunol (2024 Feb 01) | 38117781 | 2024 |
Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) augments neonatal hyperoxic lung injury ... | Stading, Rachel; Swanson, Lauren; Xia, Guobin; Jiang, Weiwu; Wang, Lihua; Couroucli, Xanthi; L ... | P42ES027725, R01ES029382 | Free Radic Biol Med (2024 Feb 01) | 38081439 | 2024 |
Quinolinyl-based multitarget-directed ligands with soluble epoxide hydrolase and fatty acid amide hy ... | Angelia, Jeannes; Duong, Leah; Yun, Faye; Mesic, Anesa; Yuan, Cassandra; Carr, Daniel; Gunari, ... | R35ES030443 | Heliyon (2024 Jun 15) | 38912512 | 2024 |
Role of the soluble epoxide hydrolase in keratinocyte proliferation and sensitivity of skin to infla ... | Naeem, Zumer; Zukunft, Sven; Huard, Arnaud; Hu, Jiong; Hammock, Bruce D; Weigert, Andreas; Frö ... | P42ES004699, R35ES030443 | Biomed Pharmacother (2024 Feb) | 38198951 | 2024 |
Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-gr ... | Paquin, Alexis; Nolin, Fayanne; Bouzriba, Chahrazed; Fortin, Sébastien; Sevrioukova, Irina F; B ... | R01ES025767 | Steroids (2024 Sep) | 38992454 | 2024 |
The Role of Autophagy in Human Uveal Melanoma and the Development of Potential Disease Biomarkers an ... | Wang, Janney Z; Paulus, Paus; Niu, Yihe; Zhu, Ling; Morisseau, Christophe; Rawling, Tristan; M ... | R35ES030443 | Biomedicines (2024 Feb 19) | 38398064 | 2024 |
Triazine herbicide prometryn alters epoxide hydrolase activity and increases cytochrome P450 metabol ... | Sule, Rasheed O; Morisseau, Christophe; Yang, Jun; Hammock, Bruce D; Gomes, Aldrin V | P42ES004699, R35ES030443 | Sci Rep (2024 Aug 19) | 39160161 | 2024 |
A bispecific nanobody with high sensitivity/efficiency for simultaneous determination of carbaryl an ... | Liu, Min-Ling; Chen, Zi-Jian; Huang, Xiao-Qing; Wang, Hong; Zhao, Jin-Li; Shen, Yu-Dong; Luo, ... | P42ES004699, R35ES030443 | Environ Pollut (2023 Oct 15) | 37517641 | 2023 |
A dendritic/tumor fusion cell vaccine enhances efficacy of nanobody-based CAR-T cells against solid ... | Sun, Shuyang; Ding, Ziqiang; Gao, Li; Hammock, Bruce D; Huang, Xianing; Xu, Zhi Ping; Wang, X ... | P42ES004699, R35ES030443 | Theranostics (2023) | 37771772 | 2023 |
Adamantyl-ureas with pyrazoles substituted by fluoroalkanes as soluble epoxide hydrolase inhibitors. | Burmistrov, Vladimir V; Morisseau, Christophe; Shkineva, Tatyana K; Danilov, Dmitry V; Gladkikh, ... | R35ES030443 | J Fluor Chem (2023 Feb) | 37638129 | 2023 |
Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10. | Richter, Felix Clemens; Friedrich, Matthias; Kampschulte, Nadja; Piletic, Klara; Alsaleh, Ghada ... | P42ES004699, R35ES030443 | EMBO J (2023 Mar 15) | 36795015 | 2023 |
Aflatoxin B1 exposure disrupts the intestinal immune function via a soluble epoxide hydrolase-mediat ... | Wang, Weicang; Wang, Yuxin; Yang, Jun; Wagner, Karen M; Hwang, Sung Hee; Cheng, Jeff; Singh, ... | P42ES004699, R35ES030443 | Ecotoxicol Environ Saf (2023 Jan 01) | 36525946 | 2023 |
Aflatoxin B1 Increases Soluble Epoxide Hydrolase in the Brain and Induces Neuroinflammation and Dopa ... | Wang, Weicang; Wang, Yuxin; Wagner, Karen M; Lee, Ruth Diana; Hwang, Sung Hee; Morisseau, Chri ... | P42ES004699, R35ES030443 | Int J Mol Sci (2023 Jun 09) | 37373086 | 2023 |
An Integrated Approach to Improve the Assay Performance of Quantum Dot-Based Lateral Flow Immunoassa ... | Wang, Yulong; Liu, Pengyan; Ye, Yuhui; Hammock, Bruce D; Zhang, Cunzheng | P42ES004699, R35ES030443 | Microchem J (2023 Sep) | 38344211 | 2023 |
Aryl hydrocarbon receptor maintains hepatic mitochondrial homeostasis in mice. | Heo, Mi Jeong; Suh, Ji Ho; Lee, Sung Ho; Poulsen, Kyle L; An, Yu A; Moorthy, Bhagavatula; Hart ... | P42ES027725, R01ES029382 | Mol Metab (2023 Jun) | 37004989 | 2023 |
Associations between Plasma Lipid Mediators and Chronic Daily Headache Outcomes in Patients Randomiz ... | Shen, Qing; Yang, Jun; Zamora, Daisy; Horowitz, Mark; Faurot, Keturah R; MacIntosh, Beth A; Ma ... | P42ES004699, R35ES030443 | Metabolites (2023 May 25) | 37367848 | 2023 |
Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Ca ... | Thai, Phung N; Ren, Lu; Xu, Wilson; Overton, James; Timofeyev, Valeriy; Nader, Carol E; Haddad ... | P42ES004699, R35ES030443 | Cardiovasc Drugs Ther (2023 Feb) | 34499283 | 2023 |
Competitive fluorescent immunosensor based on catalytic hairpin self-assembly for multiresidue detec ... | Wang, Yuanshang; Abd El-Aty, A M; Wang, Shanshan; Cui, Xueyan; Zhao, Jing; Lei, Xingmei; Xu, ... | P42ES004699, R35ES030443 | Food Chem (2023 Jul 01) | 36773354 | 2023 |
CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents ... | Leuillier, Matthieu; Duflot, Thomas; Ménoret, Séverine; Messaoudi, Hind; Djerada, Zoubir; Grous ... | P42ES004699, R35ES030443 | J Adv Res (2023 Jan) | 36585106 | 2023 |
Determinants of Meal-Induced Changes in Circulating FFA Epoxides, Diols, and Diol-to-Epoxide Ratios ... | Oh, Young Taek; Yang, Jun; Stefanovski, Darko; Hammock, Bruce; Youn, Jang H | P42ES004699, R35ES030443 | Int J Mol Sci (2023 Dec 11) | 38139180 | 2023 |
Development of a Biotinylated Nanobody-Based Gold Nanoparticle Immunochromatographic Assay for the D ... | Liu, Min-Ling; He, Xiao-Ting; Xu, Zhen-Lin; Deng, Hao; Shen, Yu-Dong; Luo, Lin; Shen, Xing; C ... | P42ES004699, R35ES030443 | J Agric Food Chem (2023 Sep 06) | 37611148 | 2023 |
Development of a Genetically Encoded Magnetic Platform in Magnetospirillum gryphiswaldense MSR-1 for ... | Wu, Sha; Tian, Jiesheng; Xue, Xianle; Tang, Zongwen; Huang, Zekai; Hammock, Bruce D; Morisseau ... | P42ES004699, R35ES030443 | Res Sq (2023 Mar 13) | 36993437 | 2023 |
Development of a sandwich ELISA for the specific quantitation of hemagglutinin (HA)-tagged proteins ... | Yin, Zihan; He, Qiyi; Yang, Huiyi; Morisseau, Christophe; El-Sheikh, El-Sayed A; Li, Dongyang; ... | P42ES004699, R35ES030443 | Anal Bioanal Chem (2023 Sep) | 37505234 | 2023 |
Development of immunoassay based on a specific antibody for sensitive detection of nicosulfuron in e ... | Gao, Qingqing; Huo, Jingqian; Chen, Lai; Yang, Dongchen; Zhang, Weihong; Jia, Bin; Xu, Xiaoto ... | P42ES004699, R35ES030443 | Sci Total Environ (2023 Feb 10) | 36400293 | 2023 |
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress i ... | Zhang, Juan; Luan, Zhi-Lin; Huo, Xiao-Kui; Zhang, Min; Morisseau, Christophe; Sun, Cheng-Peng; ... | P42ES004699, R35ES030443 | Int J Biol Sci (2023) | 36594097 | 2023 |
Dynamic Ir(III) Photosensors for the Major Human Drug-Metabolizing Enzyme Cytochrome P450 3A4. | Denison, Madeline; Ahrens, Justin J; Dunbar, Marilyn N; Warmahaye, Habon; Majeed, Aliza; Turro, ... | R01ES025767 | Inorg Chem (2023 Feb 20) | 36758158 | 2023 |
Dynamics of temporal immune responses in nonhuman primates and humans immunized with COVID-19 vaccin ... | Ravindran, Resmi; Kang, Harsharonjit; McReynolds, Cindy; Sanghar, Gursharan Kaur; Chang, W L Wi ... | P42ES004699, R35ES030443 | PLoS One (2023) | 37856429 | 2023 |
Effects of chronic secondhand smoke exposure on cardiovascular regulation and the role of soluble ep ... | Pan, Shiyue; Karey, Emma; Nieves-Cintron, Madeline; Chen, Yi-Je; Hwang, Sung Hee; Hammock, Bru ... | P42ES004699, R35ES030443 | Front Physiol (2023) | 37362438 | 2023 |
Effects of Individual Circulating FFAs on Plasma and Hepatic FFA Epoxides, Diols, and Epoxide-Diol R ... | Oh, Young Taek; Yang, Jun; Morisseau, Christophe; He, Qiyi; Hammock, Bruce; Youn, Jang H | P42ES004699, R35ES030443 | Int J Mol Sci (2023 Jun 28) | 37445935 | 2023 |
Enhancement of the liver's neuroprotective role ameliorates traumatic brain injury pathology. | Dai, Yongfeng; Dong, Jinghua; Wu, Yu; Zhu, Minzhen; Xiong, Wenchao; Li, Huanyu; Zhao, Yulu; H ... | R35ES030443 | Proc Natl Acad Sci U S A (2023 Jun 27) | 37339206 | 2023 |
Fluorine and chlorine substituted adamantyl-urea as molecular tools for inhibition of human soluble ... | Burmistrov, Vladimir V; Morisseau, Christophe; Danilov, Dmitry V; Gladkikh, Boris P; D'yachenko, ... | R35ES030443 | J Enzyme Inhib Med Chem (2023 Dec) | 37975322 | 2023 |
Generating Monoclonal Antibodies against Buprofezin and Developing Immunoassays for Its Residue Dete ... | Xu, Lingyuan; Abd El Aty, A M; Cao, Zhen; Lei, Xingmei; Zhao, Jing; Li, Jia; Gao, Song; Zhao, ... | P42ES004699, R35ES030443 | J Agric Food Chem (2023 Oct 18) | 37803933 | 2023 |
Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase attenuated particulate m ... | Zhang, Juan; Zhang, Wen-Hao; Morisseau, Christophe; Zhang, Min; Dong, Hong-Jun; Zhu, Qi-Meng; ... | P42ES004699, R35ES030443 | J Hazard Mater (2023 Sep 15) | 37406527 | 2023 |
Hepatocyte-specific disruption of soluble epoxide hydrolase attenuates abdominal aortic aneurysm for ... | Kim, David; Horimatsu, Tetsuo; Ogbi, Mourad; Goo, Brandee; Shi, Hong; Veerapaneni, Praneet; Ch ... | P42ES004699, R35ES030443 | bioRxiv (2023 Jul 11) | 37503031 | 2023 |
Inhibition of Soluble Epoxide Hydrolase Does Not Promote or Aggravate Pulmonary Hypertension in Rats ... | Leuillier, Matthieu; Platel, Valentin; Tu, Ly; Feugray, Guillaume; Thuillet, Raphaël; Groussard ... | P42ES004699, R35ES030443 | Cells (2023 Feb 20) | 36831332 | 2023 |
Inhibition of soluble epoxide hydrolase reduces paraquat neurotoxicity in rodents. | Atone, Jogen; Wagner, Karen; Koike, Shinichiro; Yang, Jun; Hwang, Sung Hee; Hammock, Bruce D | P42ES004699, R35ES030443 | Environ Toxicol Pharmacol (2023 Mar) | 36682504 | 2023 |
Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathoge ... | Hrithrik, Tafim Hossain; Lee, Dong-Hee; Singh, Nalin; Vik, Anders; Hammock, Bruce D; Kim, Yong ... | R35ES030443 | bioRxiv (2023 Jul 07) | 37461499 | 2023 |
Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding. | Sevrioukova, Irina F | R01ES025767 | J Biol Chem (2023 Sep) | 37524132 | 2023 |
Investigating a new C2-symmetric testosterone dimer and its dihydrotestosterone analog: Synthesis, a ... | Paquin, Alexis; Fortin, Laurie; Girouard, Julie; Reyes-Moreno, Carlos; Sevrioukova, Irina F; Bé ... | R01ES025767 | Eur J Med Chem (2023 Mar 15) | 36848848 | 2023 |
Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming m ... | Grimm, Sandra L; Stading, Rachel E; Robertson, Matthew J; Gandhi, Tanmay; Fu, Chenlian; Jiang, ... | P30ES030285, P42ES027725, R01ES029382 | Redox Biol (2023 Aug) | 37348155 | 2023 |
Loss of the mammalian G-protein coupled receptor, G2A, modulates severity of invasive pulmonary aspe ... | Steffan, Breanne N; Calise, Dante; Park, Sung Chul; Niu, Mengyao; Yang, Jun; Hammock, Bruce D; ... | R35ES030443 | Front Immunol (2023) | 37435068 | 2023 |
Macrophage Inactivation by Small Molecule Wedelolactone via Targeting sEH for the Treatment of LPS-I ... | Zhang, Juan; Zhang, Min; Huo, Xiao-Kui; Ning, Jing; Yu, Zhen-Long; Morisseau, Christophe; Sun, ... | P42ES004699, R35ES030443 | ACS Cent Sci (2023 Mar 22) | 36968547 | 2023 |
Metabolomic changes associated with chronic arsenic exposure in a Bangladeshi population. | Wu, Haotian; Kalia, Vrinda; Niedzwiecki, Megan M; Kioumourtzoglou, Marianthi-Anna; Pierce, Bran ... | P30ES009089, P30ES019776, P42ES033719, R01ES030945, R01ES030945, R01ES032831 | Chemosphere (2023 Apr) | 36746250 | 2023 |
Mix-and-Read Nanobody-Based Sandwich Homogeneous Split-Luciferase Assay for the Rapid Detection of H ... | He, Qiyi; McCoy, Mark R; Yang, Huiyi; Lin, Mingxia; Cui, Xiping; Zhao, Suqing; Morisseau, Chr ... | P42ES004699, R35ES030443 | Anal Chem (2023 Apr 11) | 36972550 | 2023 |
Neuroprotective effect of herbal extracts inhibiting soluble epoxide hydrolase (sEH) and cyclooxygen ... | Kulkarni, Rachana; Mehta, Richa; Goswami, Sumanta Kumar; Hammock, Bruce D; Morisseau, Christoph ... | P42ES004699, R35ES030443 | Biochem Biophys Res Commun (2023 Jul 30) | 37209564 | 2023 |
Novel inhibition of AKR1C3 and androgen receptor axis by PTUPB synergizes enzalutamide treatment in ... | Yang, Joy C; Xu, Pengfei; Ning, Shu; Wasielewski, Logan J; Adomat, Hans; Hwang, Sung Hee; Mori ... | P42ES004699, R35ES030443 | Oncogene (2023 Feb) | 36596844 | 2023 |
Polyunsaturated Fatty Acids Mend Macrophage Transcriptome, Glycome, and Phenotype in the Patients wi ... | Dover, Mary; Moseley, Taylor; Biskaduros, Adrienne; Paulchakrabarti, Mousumi; Hwang, Sung Hee; ... | P42ES004699, R35ES030443 | J Alzheimers Dis (2023) | 36373322 | 2023 |
Production of a Monoclonal Antibody for the Detection of Forchlorfenuron: Application in an Indirect ... | Lei, Xingmei; Abd El-Aty, A M; Xu, Lingyuan; Zhao, Jing; Li, Jia; Gao, Song; Zhao, Yun; She, ... | P42ES004699, R35ES030443 | Biosensors (Basel) (2023 Feb 07) | 36832005 | 2023 |
PROTAC-Mediated Selective Degradation of Cytosolic Soluble Epoxide Hydrolase Enhances ER Stress Redu ... | Wang, Yuxin; Morisseau, Christophe; Takamura, Akihiro; Wan, Debin; Li, Dongyang; Sidoli, Simon ... | P42ES004699, R35ES030443 | ACS Chem Biol (2023 Apr 21) | 36947831 | 2023 |
Quantification of soluble epoxide hydrolase inhibitors in experimental and clinical samples using th ... | Yang, Huiyi; Qi, Meng; He, Qiyi; Hwang, Sung Hee; Yang, Jun; McCoy, Mark; Morisseau, Christop ... | P42ES004699, R35ES030443 | J Pharm Anal (2023 Sep) | 37842656 | 2023 |
Quaternary Ammonium Compounds: A Chemical Class of Emerging Concern. | Arnold, William A; Blum, Arlene; Branyan, Jennifer; Bruton, Thomas A; Carignan, Courtney C; Cor ... | P30ES007033, P30ES023513, R01ES031927, T32ES007032 | Environ Sci Technol (2023 May 23) | 37157132 | 2023 |
Regulatory lipid vicinal diols counteract the biological activity of epoxy fatty acids and can act a ... | McReynolds, Cindy; Hammock, Bruce; Morisseau, Christophe | P42ES004699, R35ES030443 | Pharmacol Ther (2023 Aug) | 37268114 | 2023 |
Residue Analysis and Risk Exposure Assessment of Multiple Pesticides in Tomato and Strawberry and Th ... | El-Sheikh, El-Sayed A; Li, Dongyang; Hamed, Ibrahim; Ashour, Mohamed-Bassem; Hammock, Bruce D | P42ES004699, R35ES030443 | Foods (2023 May 10) | 37238754 | 2023 |
Role of soluble epoxide hydrolase in the abnormal activation of fibroblast-like synoviocytes from pa ... | Pu, Yaoyu; Cheng, Ruijuan; Zhang, Qiuping; Huang, Tianwen; Lu, Chenyang; Tang, Zhigang; Zhong, ... | P42ES004699, R35ES030443 | Clin Immunol (2023 Dec) | 38013165 | 2023 |
Screening and Biological Evaluation of Soluble Epoxide Hydrolase Inhibitors: Assessing the Role of H ... | Vázquez, Javier; Ginex, Tiziana; Herrero, Albert; Morisseau, Christophe; Hammock, Bruce D; Luqu ... | P42ES004699, R35ES030443 | J Chem Inf Model (2023 May 22) | 37141492 | 2023 |
Soluble Epoxide Hydrolase Contributes to Cell Senescence and ER Stress in Aging Mice Colon. | Wang, Weicang; Wagner, Karen M; Wang, Yuxin; Singh, Nalin; Yang, Jun; He, Qiyi; Morisseau, Ch ... | P42ES004699, R35ES030443 | Int J Mol Sci (2023 Feb 26) | 36901999 | 2023 |
Soluble epoxide hydrolase inhibition enhances production of specialized pro-resolving lipid mediator ... | Abdalla, Henrique B; Alvarez, Carla; Wu, Yu-Chiao; Rojas, Paola; Hammock, Bruce D; Maddipati, ... | P42ES004699, R35ES030443 | Br J Pharmacol (2023 Jun) | 36508312 | 2023 |
Soluble epoxide hydrolase inhibitor blockage microglial cell activation in subnucleus caudalis in a ... | Tarkany Basting, Rosanna; Henrique Napimoga, Marcelo; Antônio Trindade Silva, Carlos; Ballassini ... | P42ES004699, R35ES030443 | Int Immunopharmacol (2023 Jul) | 37230034 | 2023 |
Soluble epoxide hydrolase-targeting PROTAC activates AMPK and inhibits endoplasmic reticulum stress. | Peyman, Mona; Barroso, Emma; Turcu, Andreea L; Estrany Jr, Francesc; Smith, Dáire; Jurado-Aguil ... | P42ES004699, R35ES030443 | Biomed Pharmacother (2023 Dec) | 37826940 | 2023 |
Structural Insights into the Stability and Recognition Mechanism of the Antiquinalphos Nanobody for ... | Li, Jia-Dong; Wu, Guang-Pei; Li, Li-Hua; Wang, Lan-Teng; Liang, Yi-Fan; Fang, Ru-Yu; Zhang, Q ... | P42ES004699, R35ES030443 | Anal Chem (2023 Aug 01) | 37428097 | 2023 |
Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to a ... | Angelia, Jeannes; Weng, Xiaohui; Solomatov, Aleksei; Chin, Christopher; Fernandez, Alyssa; Huds ... | P42ES004699, R35ES030443 | Prostaglandins Other Lipid Mediat (2023 Feb) | 36529320 | 2023 |
Structure-Directed Discovery of Potent Soluble Epoxide Hydrolase Inhibitors for the Treatment of Inf ... | Chen, Yuanguang; Chen, Lu; Xu, Huashen; Cao, Ruolin; Morisseau, Christophe; Zhang, Maoying; Sh ... | P42ES004699, R35ES030443 | J Med Chem (2023 Feb 23) | 36689364 | 2023 |
The Folic Acid and Creatine Trial: Treatment Effects of Supplementation on Arsenic Methylation Indic ... | Abuawad, Ahlam K; Bozack, Anne K; Navas-Acien, Ana; Goldsmith, Jeff; Liu, Xinhua; Hall, Megan ... | P30ES009089, R01ES030945, R01ES030945 | Environ Health Perspect (2023 Mar) | 36976258 | 2023 |
The Generation of a Nanobody-Based ELISA for Human Microsomal Epoxide Hydrolase. | He, Qiyi; McCoy, Mark R; Qi, Meng; Morisseau, Christophe; Yang, Huiyi; Xu, Chengpeng; Shey, R ... | P42ES004699, R35ES030443 | Int J Mol Sci (2023 Sep 28) | 37834144 | 2023 |
The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via ... | Luo, Ailin; Wu, Zifeng; Li, Shan; McReynolds, Cindy B; Wang, Di; Liu, Hanyu; Huang, Chaoli; H ... | P42ES004699, R35ES030443 | J Transl Med (2023 Feb 02) | 36732752 | 2023 |
Therapy of autoimmune inflammation in sporadic amyotrophic lateral sclerosis: Dimethyl fumarate and ... | Zamiri, Kurosh; Kesari, Santosh; Paul, Ketema; Hwang, Sung Hee; Hammock, Bruce; Kaczor-Urbanowi ... | R35ES030443 | FASEB J (2023 Aug) | 37436778 | 2023 |
"Ready-to-use" immunosensor for the detection of small molecules with fast readout. | Ding, Yuan; Cui, Panpan; Chen, He; Li, Jiao; Huang, Lianrun; González-Sapienza, Gualberto; Ham ... | P42ES004699, R35ES030443 | Biosens Bioelectron (2022 Apr 01) | 35007993 | 2022 |
A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column De ... | Wan, Debin; Morisseau, Christophe; Hammock, Bruce D; Yang, Jun | P42ES004699, R35ES030443 | Molecules (2022 Jan 03) | 35011515 | 2022 |
A highly sensitive bio-barcode immunoassay for multi-residue detection of organophosphate pesticides ... | Xu, Lingyuan; Zhang, Xiuyuan; Abd El-Aty, A M; Wang, Yuanshang; Cao, Zhen; Jia, Huiyan; Salvad ... | R35ES030443 | J Pharm Anal (2022 Aug) | 36105157 | 2022 |
A Polydopamine-Coated Gold Nanoparticles Quenching Quantum Dots-Based Dual-Readout Lateral Flow Immu ... | Mao, Xinxin; Wang, Yulong; Jiang, Lan; Zhang, Hanxiaoya; Zhao, Yun; Liu, Pengyan; Liu, Juanju ... | P42ES004699, R35ES030443 | Biosensors (Basel) (2022 Jan 29) | 35200343 | 2022 |
Anti-Inflammatory Activity of Soluble Epoxide Hydrolase Inhibitors Based on Selenoureas Bearing an A ... | Burmistrov, Vladimir; Morisseau, Christophe; Babkov, Denis A; Golubeva, Tatiana; Pitushkin, Dmi ... | R35ES030443 | Int J Mol Sci (2022 Sep 14) | 36142611 | 2022 |
Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P ... | Zhou, Guodong; Jiang, Weiwu; Xia, Guobin; Wang, Lihua; Richardson, Molly; Chu, Chun; Moorthy, ... | P30ES030285, P42ES027725, R01ES029382 | Antioxidants (Basel) (2022 Jan 05) | 35052622 | 2022 |
Camelization of a murine single-domain antibody against aflatoxin B1 and its antigen-binding analysi ... | Pang, Qian; Chen, Yanhong; Mukhtar, Hina; Xiong, Jing; Wang, Xiaohong; Xu, Ting; Hammock, Bru ... | P42ES004699, R35ES030443 | Mycotoxin Res (2022 Feb) | 35023020 | 2022 |
Clinical and Preclinical Evidence for Roles of Soluble Epoxide Hydrolase in Osteoarthritis Knee Pain ... | Gowler, Peter R W; Turnbull, James; Shahtaheri, Mohsen; Gohir, Sameer; Kelly, Tony; McReynolds, ... | P42ES004699, R35ES030443 | Arthritis Rheumatol (2022 Apr) | 34672113 | 2022 |
Crystal Structure of CYP3A4 Complexed with Fluorol Identifies the Substrate Access Channel as a High ... | Sevrioukova, Irina F | R01ES025767 | Int J Mol Sci (2022 Oct 20) | 36293445 | 2022 |
Design and Characterization of a Novel Hapten and Preparation of Monoclonal Antibody for Detecting A ... | Xu, Lingyuan; Abd El-Aty, A M; Shim, Jae-Han; Eun, Jong-Bang; Lei, Xingmei; Zhao, Jing; Zhang, ... | P42ES004699, R35ES030443 | Foods (2022 Jun 13) | 35741925 | 2022 |
Development of a Rapid Gold Nanoparticle Immunochromatographic Strip Based on the Nanobody for Detec ... | Zhou, Hui; He, Cong; Li, Zhenfeng; Huo, Jingqian; Xue, Yu; Xu, Xiaotong; Qi, Meng; Chen, Lai ... | P42ES004699, R35ES030443 | Biosensors (Basel) (2022 Jan 30) | 35200344 | 2022 |
Discovery and In Vivo Proof of Concept of a Highly Potent Dual Inhibitor of Soluble Epoxide Hydrolas ... | Codony, Sandra; Pont, Caterina; Griñán-Ferré, Christian; Di Pede-Mattatelli, Ania; Calvó-Tusell, ... | P42ES004699, R35ES030443 | J Med Chem (2022 Mar 24) | 35271276 | 2022 |
Fluonanobody-based nanosensor via fluorescence resonance energy transfer for ultrasensitive detectio ... | Su, Benchao; Zhang, Zhong; Sun, Zhichang; Tang, Zongwen; Xie, Xiaoxia; Chen, Qi; Cao, Hongmei ... | P42ES004699, R35ES030443 | J Hazard Mater (2022 Jan 15) | 34411960 | 2022 |
Generation of bioluminescent enzyme immunoassay for ferritin by single-chain variable fragment and i ... | He, Qiyi; Yang, Li; Lin, Mingxia; Yang, Huiyi; Cui, Xiping; McCoy, Mark R; Hammock, Bruce D; ... | P42ES004699, R35ES030443 | Anal Bioanal Chem (2022 Sep) | 35945290 | 2022 |
Improved ELISA for linoleate-derived diols in human plasma utilizing a polyHRP-based secondary trace ... | Singh, Nalin; Li, Dongyang; McReynolds, Cindy B; Morisseau, Christophe; Hammock, Bruce D | P42ES004699, R35ES030443 | Anal Methods (2022 May 13) | 35481804 | 2022 |
Interaction of CYP3A4 with Rationally Designed Ritonavir Analogues: Impact of Steric Constraints Imp ... | Samuels, Eric R; Sevrioukova, Irina F | R01ES025767 | Int J Mol Sci (2022 Jun 30) | 35806297 | 2022 |
Ir(III)-Based Agents for Monitoring the Cytochrome P450 3A4 Active Site Occupancy. | Denison, Madeline; Steinke, Sean J; Majeed, Aliza; Turro, Claudia; Kocarek, Thomas A; Sevriouko ... | R01ES025767 | Inorg Chem (2022 Sep 05) | 35994607 | 2022 |
Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal m ... | Sun, Cheng-Peng; Zhou, Jun-Jun; Yu, Zhen-Long; Huo, Xiao-Kui; Zhang, Juan; Morisseau, Christop ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2022 Mar 01) | 35217618 | 2022 |
Metabolism of Benzalkonium Chloride by CYP-Mediated ω-Oxidation and C-C Cleavage Followed by β-Oxida ... | Seguin, Ryan; Xu, Libin | P30ES007033, R01ES031927, T32ES007032 | FASEB J (2022 May) | 35567457 | 2022 |
Monosodium glutamate consumption reduces the renal excretion of trimethylamine N-oxide and the abund ... | Kyaw, Thin Su; Sukmak, Manatsaphon; Nahok, Kanokwan; Sharma, Amod; Silsirivanit, Atit; Lert-Itt ... | R35ES030443 | Biochem Biophys Res Commun (2022 Nov 19) | 36155062 | 2022 |
Nanobodies for Accurate Recognition of Iso-tenuazonic Acid and Development of Sensitive Immunoassay ... | Wang, Feng; Yang, Yuan-Yuan; Wan, De-Bin; Li, Jia-Dong; Liang, Yi-Fan; Li, Zhen-Feng; Shen, Y ... | P42ES004699, R35ES030443 | Food Control (2022 Jun) | 35989708 | 2022 |
Novel aerosol treatment of airway hyper-reactivity and inflammation in a murine model of asthma with ... | Zhang, Chuanzhen; Li, Wei; Li, Xiyuan; Wan, Debin; Mack, Savannah; Zhang, Jingjing; Wagner, K ... | P30ES023513, P42ES004699, R35ES030443 | PLoS One (2022) | 35443010 | 2022 |
Omega-6 Polyunsaturated Fatty Acids Enhance Tumor Aggressiveness in Experimental Lung Cancer Model: ... | Montecillo-Aguado, Mayra; Tirado-Rodriguez, Belen; Antonio-Andres, Gabriela; Morales-Martinez, M ... | P42ES004699, R35ES030443 | Int J Mol Sci (2022 May 31) | 35682855 | 2022 |
Phosphate-triggered ratiometric fluoroimmunoassay based on nanobody-alkaline phosphatase fusion for ... | Chen, Zi-Jian; Wu, Hui-Ling; Shen, Yu-Dong; Wang, Hong; Zhang, Yi-Feng; Hammock, Bruce; Li, Z ... | P42ES004699, R35ES030443 | J Hazard Mater (2022 Feb 15) | 34629198 | 2022 |
Production and Characterization of Biotinylated Anti-fenitrothion Nanobodies and Development of Sens ... | Chen, Zi-Jian; Zhang, Yi-Feng; Chen, Jia-Lin; Lin, Ze-Shan; Wu, Min-Fu; Shen, Yu-Dong; Luo, L ... | P42ES004699, R35ES030443 | J Agric Food Chem (2022 Apr 06) | 35333506 | 2022 |
Rapid Measurement of Residual Kanamycin Using Highly Specific Biomimetic Recognition Paper-Based Chi ... | Song, Jian; He, Kaiyu; Xing, Bingcong; Pei, Yong; Wang, Dingnan; Wang, Yang; Li, Shiyan; Li, ... | P42ES004699, R35ES030443 | Anal Chem (2022 Dec 20) | 36458677 | 2022 |
Recent Advances in Rapid Detection Techniques for Pesticide Residue: A Review. | Xu, Lingyuan; Abd El-Aty, A M; Eun, Jong-Bang; Shim, Jae-Han; Zhao, Jing; Lei, Xingmei; Gao, ... | P42ES004699, R35ES030443 | J Agric Food Chem (2022 Oct 19) | 36210513 | 2022 |
Reply to Chao et al. Comment on "Nahok et al. Monosodium Glutamate Induces Changes in Hepatic and Re ... | Nahok, Kanokwan; Selmi, Carlo; Sukmak, Manatsaphon; Phetcharaburanin, Jutarop; Li, Jia V; Silsi ... | R35ES030443 | Nutrients (2022 Oct 19) | 36297071 | 2022 |
Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth. | Naeem, Zumer; Zukunft, Sven; Günther, Stephan; Liebner, Stefan; Weigert, Andreas; Hammock, Bru ... | P42ES004699, R35ES030443 | Pflugers Arch (2022 Sep) | 35648219 | 2022 |
sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate im ... | Bergmann, Christian B; McReynolds, Cindy B; Wan, Debin; Singh, Nalin; Goetzman, Holly; Caldwell ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2022 Mar 29) | 35312372 | 2022 |
Soluble epoxide hydrolase inhibition alleviates chemotherapy induced neuropathic pain. | Takeshita, Ashley A; Hammock, Bruce D; Wagner, Karen M | R35ES030443 | Front Pain Res (Lausanne) (2022) | 36700145 | 2022 |
Soluble epoxide hydrolase inhibition avoid formalin-induced inflammatory hyperalgesia in the temporo ... | Abdalla, Henrique Ballassini; Napimoga, Marcelo Henrique; Teixeira, Juliana Maia; Trindade-da-Sil ... | P42ES004699, R35ES030443 | Inflammopharmacology (2022 Jun) | 35303234 | 2022 |
Soluble Epoxide Hydrolase Is Associated with Postprandial Anxiety Decrease in Healthy Adult Women. | Nguyen, Nhien; Morisseau, Christophe; Li, Dongyang; Yang, Jun; Lam, Eileen; Woodside, D Blake; ... | P42ES004699, R35ES030443 | Int J Mol Sci (2022 Oct 05) | 36233100 | 2022 |
Structure-guided discovery of potent and oral soluble epoxide hydrolase inhibitors for the treatment ... | Du, Fangyu; Cao, Ruolin; Chen, Lu; Sun, Jianwen; Shi, Yajie; Fu, Yang; Hammock, Bruce D; Zhen ... | P42ES004699, R35ES030443 | Acta Pharm Sin B (2022 Mar) | 35530144 | 2022 |
Synthesis, In Vitro Profiling, and In Vivo Evaluation of Benzohomoadamantane-Based Ureas for Viscera ... | Codony, Sandra; Entrena, José M; Calvó-Tusell, Carla; Jora, Beatrice; González-Cano, Rafael; Os ... | P42ES004699, R35ES030443 | J Med Chem (2022 Oct 27) | 36222708 | 2022 |
The Aryl Hydrocarbon Receptor (AHR): A Novel Therapeutic Target for Pulmonary Diseases? | Shivanna, Binoy; Chu, Chun; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Int J Mol Sci (2022 Jan 28) | 35163440 | 2022 |
The epoxy fatty acid pathway enhances cAMP in mammalian cells through multiple mechanisms. | Matsumoto, Naoki; Singh, Nalin; Lee, Kin Sing; Barnych, Bogdan; Morisseau, Christophe; Hammock, ... | P42ES004699, R35ES030443 | Prostaglandins Other Lipid Mediat (2022 Oct) | 35779854 | 2022 |
The Role of Hydrolases in Biology and Xenobiotics Metabolism. | Morisseau, Christophe | P42ES004699, R35ES030443 | Int J Mol Sci (2022 Apr 28) | 35563260 | 2022 |
Ureas derived from camphor and fenchone reveal enantiomeric preference of human soluble epoxide hydr ... | Burmistrov, Vladimir; Morisseau, Christophe; Pitushkin, Dmitry; Fayzullin, Robert R; Karlov, Dm ... | R35ES030443 | Results Chem (2022 Jan) | 37601415 | 2022 |
Using a quantum dot bead-based lateral flow immunoassay to broadly detect the adulteration of PDE-5 ... | Song, Mingshu; Wu, Qin; Liu, Beibei; Li, Pan; Jiang, Lan; Wang, Yulong; Dong, Sa; Xiong, Yon ... | P42ES004699, R35ES030443 | Anal Methods (2022 Jul 07) | 35723455 | 2022 |
2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammator ... | Martín-López, Juan; Codony, Sandra; Bartra, Clara; Morisseau, Christophe; Loza, María Isabel; S ... | P42ES004699, R35ES030443 | Pharmaceuticals (Basel) (2021 Dec 17) | 34959721 | 2021 |
A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, ... | Jonnalagadda, Deepa; Wan, Debin; Chun, Jerold; Hammock, Bruce D; Kihara, Yasuyuki | P42ES004699, R35ES030443 | Int J Mol Sci (2021 Apr 28) | 33925035 | 2021 |
Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis. | Mavangira, Vengai; Kuhn, Matthew J; Abuelo, Angel; Morisseau, Christophe; Hammock, Bruce D; Sor ... | P42ES004699, R35ES030443 | Antioxidants (Basel) (2021 May 20) | 34065244 | 2021 |
Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug ... | Singh, Nalin; Barnych, Bogdan; Wagner, Karen M; Wan, Debin; Morisseau, Christophe; Hammock, Br ... | P42ES004699, R35ES030443 | ACS Omega (2021 Mar 16) | 33748630 | 2021 |
Autism-like Behaviors in Male Juvenile Offspring after Maternal Glyphosate Exposure. | Pu, Yaoyu; Ma, Li; Shan, Jiajing; Wan, Xiayun; Hammock, Bruce D; Hashimoto, Kenji | P42ES004699, R35ES030443 | Clin Psychopharmacol Neurosci (2021 Aug 31) | 34294625 | 2021 |
Carcinogenesis: Failure of resolution of inflammation? | Fishbein, Anna; Hammock, Bruce D; Serhan, Charles N; Panigrahy, Dipak | P42ES004699, R35ES030443 | Pharmacol Ther (2021 Feb) | 32891711 | 2021 |
COX-2/sEH Dual Inhibitor PTUPB Alleviates CCl 4 -Induced Liver Fibrosis and Portal Hypertension. | Zhao, Zhifeng; Zhang, Chihao; Lin, Jiayun; Zheng, Lei; Li, Hongjie; Qi, Xiaoliang; Huo, Haizh ... | P42ES004699, R35ES030443 | Front Med (Lausanne) (2021) | 35004731 | 2021 |
Development of a chemiluminescence immunoassay for detection of tenuazonic acid mycotoxin in fruit j ... | Wang, Feng; Wan, De-Bin; Shen, Yu-Dong; Tian, Yuan-Xin; Xiao, Zhi-Li; Xu, Zhen-Lin; Yang, Jin ... | R35ES030443 | Anal Methods (2021 04 22) | 33885655 | 2021 |
Development of a nanobody-based ELISA for the detection of the insecticides cyantraniliprole and chl ... | Xu, Bojie; Wang, Kai; Vasylieva, Natalia; Zhou, Hang; Xue, Xianle; Wang, Baomin; Li, Qing X; ... | P42ES004699, R35ES030443 | Anal Bioanal Chem (2021 Apr) | 33580830 | 2021 |
Development of a sensitive non-competitive immunoassay via immunocomplex binding peptide for the det ... | Fu, Hui-Jun; Chen, Zi-Jian; Wang, Hong; Luo, Lin; Wang, Yu; Huang, Ri-Ming; Xu, Zhen-Lin; Ham ... | P42ES004699, R35ES030443 | J Hazard Mater (2021 03 15) | 33525128 | 2021 |
Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t- ... | Yang, Yang; Xu, Xinyun; Wu, Haoying; Yang, Jun; Chen, Jiangang; Morisseau, Christophe; Hammock ... | P42ES004699, R35ES030443 | Int J Mol Sci (2021 Jul 31) | 34361032 | 2021 |
Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopo ... | Du, Fangyu; Sun, Wenjiao; Morisseau, Christophe; Hammock, Bruce D; Bao, Xuefei; Liu, Qiu; Wang ... | P42ES004699, R35ES030443 | Eur J Med Chem (2021 Nov 05) | 34218083 | 2021 |
Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products. | Sun, Cheng-Peng; Zhang, Xin-Yue; Morisseau, Christophe; Hwang, Sung Hee; Zhang, Zhan-Jun; Hammo ... | P42ES004699, R35ES030443 | J Med Chem (2021 01 14) | 33369424 | 2021 |
Dual sEH/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicit ... | Jankiewicz, Wojciech K; Barnett, Scott D; Stavniichuk, Anna; Hwang, Sung Hee; Hammock, Bruce D; ... | P42ES004699, R35ES030443 | Front Pharmacol (2021) | 34955823 | 2021 |
Effect of sex chromosomes versus hormones in neonatal lung injury. | Grimm, Sandra L; Dong, Xiaoyu; Zhang, Yuhao; Carisey, Alexandre F; Arnold, Arthur P; Moorthy, ... | P30ES030285, P42ES027725, R01ES029382 | JCI Insight (2021 07 08) | 34061778 | 2021 |
Eicosanoid regulation of debris-stimulated metastasis. | Deng, Jianjun; Yang, Haixia; Haak, Victoria M; Yang, Jun; Kipper, Franciele C; Barksdale, Chan ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2021 10 12) | 34607951 | 2021 |
EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increa ... | Gautheron, Jeremie; Morisseau, Christophe; Chung, Wendy K; Zammouri, Jamila; Auclair, Martine; ... | P42ES004699, R35ES030443 | Elife (2021 08 03) | 34342583 | 2021 |
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase I ... | Codony, Sandra; Calvó-Tusell, Carla; Valverde, Elena; Osuna, Sílvia; Morisseau, Christophe; Loz ... | P42ES004699, R35ES030443 | J Med Chem (2021 05 13) | 33945278 | 2021 |
Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty a ... | Wilt, Stephanie; Kodani, Sean; Valencia, Leah; Hudson, Paula K; Sanchez, Stephanie; Quintana, ... | P42ES004699, R35ES030443 | Bioorg Med Chem (2021 Dec 01) | 34794001 | 2021 |
Fusion expression of nanobodies specific for the insecticide fipronil on magnetosomes in Magnetospir ... | Wu, Sha; Ma, Fengfei; He, Jinxin; Li, Qing X; Hammock, Bruce D; Tian, Jiesheng; Xu, Ting | P42ES004699, R35ES030443 | J Nanobiotechnology (2021 Jan 19) | 33468141 | 2021 |
Generation of Dual functional Nanobody-Nanoluciferase Fusion and its potential in Bioluminescence En ... | Yu, Sheng; Li, Zhenfeng; Li, Jingzhang; Zhao, Shimei; Wu, Shanguang; Liu, Hongjing; Bi, Xiong ... | P42ES004699, R35ES030443 | Sens Actuators B Chem (2021 Jun 01) | 35250176 | 2021 |
Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat d ... | Koike, Shinichiro; Hsu, Ming-Fo; Bettaieb, Ahmed; Chu, Bryan; Matsumoto, Naoki; Morisseau, Chr ... | P42ES004699, R35ES030443 | Free Radic Biol Med (2021 Aug 20) | 34038767 | 2021 |
Highly specific nanobody against herbicide 2,4-dichlorophenoxyacetic acid for monitoring of its cont ... | Li, Zhen-Feng; Dong, Jie-Xian; Vasylieva, Natalia; Cui, Yong-Liang; Wan, De-Bin; Hua, Xiu-De; ... | P42ES004699, R35ES030443 | Sci Total Environ (2021 Jan 20) | 32906044 | 2021 |
HIV-related Neuropathy: Pathophysiology, Treatment and Challenges. | Jazebi, Noushin; Evans, Chad; Kadaru, Hima S; Kompella, Divya; Raji, Mukaila; Fang, Felix; Pap ... | P42ES004699, R35ES030443 | J Neurol Exp Neurosci (2021) | 35252633 | 2021 |
Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different ... | Tiwari, Shuchita; Yang, Jun; Morisseau, Christophe; Durbin-Johnson, Blythe; Hammock, Bruce D; G ... | P42ES004699, R35ES030443 | Sci Rep (2021 03 29) | 33782432 | 2021 |
Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in t ... | Pressly, Brandon; Lee, Ruth D; Barnych, Bogdan; Hammock, Bruce D; Wulff, Heike | R35ES030443 | Mol Pharmacol (2021 01) | 33109687 | 2021 |
Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out ... | Wang, Siming; Ishima, Tamaki; Qu, Youge; Shan, Jiajing; Chang, Lijia; Wei, Yan; Zhang, Jianch ... | P42ES004699, R35ES030443 | J Affect Disord (2021 09 01) | 34147969 | 2021 |
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β sig ... | Sun, Cheng-Peng; Zhang, Xin-Yue; Zhou, Jun-Jun; Huo, Xiao-Kui; Yu, Zhen-Long; Morisseau, Chris ... | P42ES004699, R35ES030443 | Food Chem Toxicol (2021 Oct) | 34411643 | 2021 |
Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Eviden ... | Wang, Yuxin; Wagner, Karen M; Morisseau, Christophe; Hammock, Bruce D | R35ES030443 | J Pain Res (2021) | 33488116 | 2021 |
Innovative C2-symmetric testosterone and androstenedione dimers: Design, synthesis, biological evalu ... | Paquin, Alexis; Oufqir, Yassine; Sevrioukova, Irina F; Reyes-Moreno, Carlos; Bérubé, Gervais | R01ES025767 | Eur J Med Chem (2021 Aug 05) | 33933755 | 2021 |
Molecular docking-guided synthesis of NSAID-glucosamine bioconjugates and their evaluation as COX-1/ ... | Jones Lipinski, Rachel A; Thillier, Yann; Morisseau, Christophe; Sebastiano Jr, Christopher S; S ... | R35ES030443 | Chem Biol Drug Des (2021 07) | 33955172 | 2021 |
Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implica ... | Stading, Rachel; Gastelum, Grady; Chu, Chun; Jiang, Weiwu; Moorthy, Bhagavatula | P30ES030285, P42ES027725, R01ES029382 | Semin Cancer Biol (2021 11) | 34242741 | 2021 |
Multitarget molecule, PTUPB, to treat diabetic nephropathy in rats. | Khan, Md Abdul Hye; Hwang, Sung Hee; Barnett, Scott D; Stavniichuk, Anna; Jankiewicz, Wojciech ... | R35ES030443 | Br J Pharmacol (2021 11) | 34255857 | 2021 |
Nanobody-based chimeric antigen receptor T cells designed by CRISPR/Cas9 technology for solid tumor ... | Mo, Fengzhen; Duan, Siliang; Jiang, Xiaobing; Yang, Xiaomei; Hou, Xiaoqiong; Shi, Wei; Carlos, ... | P42ES004699, R35ES030443 | Signal Transduct Target Ther (2021 02 25) | 33627635 | 2021 |
New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via R ... | Singh, Nalin; Vik, Anders; Lybrand, Daniel B; Morisseau, Christophe; Hammock, Bruce D | P42ES004699, R35ES030443 | Chem Res Toxicol (2021 Dec 20) | 34817988 | 2021 |
Nutrition, one-carbon metabolism and arsenic methylation. | Abuawad, Ahlam; Bozack, Anne K; Saxena, Roheeni; Gamble, Mary V | P30ES009089, R01ES030945, R01ES030945 | Toxicology (2021 Jun 15) | 33905762 | 2021 |
Pharmacokinetics, Metabolite Measurement and Biomarker Identification of Dermal Exposure to Permethr ... | Buchholz, Bruce A; Ahn, KiChang; Huang, Huazhang; Gee, Shirley J; Stewart, Benjamin; Ognibene, ... | P42ES004699, R35ES030443 | Toxicol Sci (2021 Jun 21) | 34152416 | 2021 |
Pharmacokinetics, Metabolite Measurement, and Biomarker Identification of Dermal Exposure to Permeth ... | Buchholz, Bruce A; Ahn, Ki Chang; Huang, Huazhang; Gee, Shirley J; Stewart, Benjamin J; Ogniben ... | P42ES004699, R35ES030443 | Toxicol Sci (2021 Aug 30) | 34460930 | 2021 |
Photosensitive Ru(II) Complexes as Inhibitors of the Major Human Drug Metabolizing Enzyme CYP3A4. | Toupin, Nicholas; Steinke, Sean J; Nadella, Sandeep; Li, Ao; Rohrabaugh Jr, Thomas N; Samuels, ... | R01ES025767 | J Am Chem Soc (2021 06 23) | 34110801 | 2021 |
Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections. | McReynolds, Cindy B; Cortes-Puch, Irene; Ravindran, Resmi; Khan, Imran H; Hammock, Bruce G; Shi ... | P42ES004699, R35ES030443 | Front Physiol (2021) | 33868029 | 2021 |
Preservation of epoxyeicosatrienoic acid bioavailability prevents renal allograft dysfunction and ca ... | Duflot, Thomas; Laurent, Charlotte; Soudey, Anne; Fonrose, Xavier; Hamzaoui, Mouad; Iacob, Mic ... | P42ES004699, R35ES030443 | Sci Rep (2021 02 12) | 33580125 | 2021 |
Rational Design of CYP3A4 Inhibitors: A One-Atom Linker Elongation in Ritonavir-Like Compounds Leads ... | Samuels, Eric R; Sevrioukova, Irina F | R01ES025767 | Int J Mol Sci (2021 Jan 16) | 33467005 | 2021 |
Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty A ... | Morisseau, Christophe; Kodani, Sean D; Kamita, Shizuo G; Yang, Jun; Lee, Kin Sing Stephen; Hamm ... | P42ES004699, R35ES030443 | Int J Mol Sci (2021 May 08) | 34066758 | 2021 |
Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative D ... | Burke, Rebecca; Chu, Chun; Zhou, Guo-Dong; Putluri, Vasanta; Putluri, Nagireddy; Stading, Rach ... | P30ES030285, P42ES027725, R01ES029382 | Oxid Med Cell Longev (2021) | 34691356 | 2021 |
Sex-Specific Differences in Resolution of Airway Inflammation in Fat-1 Transgenic Mice Following Rep ... | Ulu, Arzu; Velazquez, Jalene V; Burr, Abigail; Sveiven, Stefanie N; Yang, Jun; Bravo, Carissa; ... | P42ES004699, R35ES030443 | Front Pharmacol (2021) | 35095496 | 2021 |
Smartphone-Based Dual-Channel Immunochromatographic Test Strip with Polymer Quantum Dot Labels for S ... | Zhao, Yuting; Ruan, Xiaofan; Song, Yang; Smith, Jordan N; Vasylieva, Natalia; Hammock, Bruce D ... | P42ES004699, R35ES030443 | Anal Chem (2021 10 12) | 34591463 | 2021 |
Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mT ... | Wang, Luyun; Zhao, Daqiang; Tang, Liangqiu; Li, Huihui; Liu, Zhaoyu; Gao, Jingwei; Edin, Matt ... | P42ES004699, R35ES030443 | J Mol Cell Cardiol (2021 05) | 33378686 | 2021 |
Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation. | Wagner, Karen M; Yang, Jun; Morisseau, Christophe; Hammock, Bruce D | P42ES004699, R35ES030443 | Front Pharmacol (2021) | 34975481 | 2021 |
Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease. | Mello, Aline; Hsu, Ming-Fo; Koike, Shinichiro; Chu, Bryan; Cheng, Jeff; Yang, Jun; Morisseau, ... | P42ES004699, R35ES030443 | Cell Mol Gastroenterol Hepatol (2021) | 33068774 | 2021 |
Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury. | Jamieson, K Lockhart; Darwesh, Ahmed M; Sosnowski, Deanna K; Zhang, Hao; Shah, Saumya; Zhabyeye ... | P42ES004699, R35ES030443 | Int J Mol Sci (2021 Feb 08) | 33567578 | 2021 |
Soluble epoxide hydrolase inhibition improves cognitive function and parenchymal artery dilation in ... | Matin, Nusrat; Fisher, Courtney; Lansdell, Theresa A; Hammock, Bruce D; Yang, Jun; Jackson, Wi ... | P42ES004699, R35ES030443 | Microcirculation (2021 01) | 32767848 | 2021 |
Sortase-Mediated Phage Decoration for Analytical Applications. | Ding, Yuan; Chen, He; Li, Jiao; Huang, Lianrun; Song, Guangyue; Li, Zhenfeng; Hua, Xiude; Gon ... | P42ES004699, R35ES030443 | Anal Chem (2021 08 31) | 34415158 | 2021 |
Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Impo ... | McReynolds, Cindy B; Yang, Jun; Guedes, Alonso; Morisseau, Christophe; Garcia, Roberto; Knych, ... | P42ES004699, R35ES030443 | Molecules (2021 Aug 19) | 34443621 | 2021 |
Structural Basis for the Diminished Ligand Binding and Catalytic Ability of Human Fetal-Specific CYP ... | Sevrioukova, Irina F | R01ES025767 | Int J Mol Sci (2021 May 29) | 34072457 | 2021 |
Structural Dynamics of Cytochrome P450 3A4 in the Presence of Substrates and Cytochrome P450 Reducta ... | Ducharme, Julie; Sevrioukova, Irina F; Thibodeaux, Christopher J; Auclair, Karine | R01ES025767 | Biochemistry (2021 07 20) | 34196520 | 2021 |
Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors. | An, Guohua; Lee, Kin Sing Stephen; Yang, Jun; Hammock, Bruce D | P42ES004699, R35ES030443 | J Clin Pharmacol (2021 04) | 33078430 | 2021 |
The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury. | Stading, Rachel; Couroucli, Xanthi; Lingappan, Krithika; Moorthy, Bhagavatula | P30ES030285, P42ES027725, R01ES029382 | Expert Opin Drug Metab Toxicol (2021 Feb) | 33215946 | 2021 |
TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs ne ... | Bergmann, Christian B; Hammock, Bruce D; Wan, Debin; Gogolla, Falk; Goetzman, Holly; Caldwell, ... | P42ES004699, R35ES030443 | Sci Rep (2021 08 16) | 34400718 | 2021 |
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhi ... | Bukhari, I A; Alorainey, B I; Al-Motrefi, A A; Mahmoud, A; Campbell, W B; Hammock, B D | P42ES004699, R35ES030443 | Eur Rev Med Pharmacol Sci (2020 08) | 32767352 | 2020 |
2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Mode ... | Codony, Sandra; Pujol, Eugènia; Pizarro, Javier; Feixas, Ferran; Valverde, Elena; Loza, M Isab ... | P42ES004699, R35ES030443 | J Med Chem (2020 Sep 10) | 32787085 | 2020 |
A COX-2/sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via ... | Zhang, Yan-Feng; Sun, Chen-Chen; Duan, Jia-Xi; Yang, Hui-Hui; Zhang, Chen-Yu; Xiong, Jian-Bing ... | P42ES004699, R35ES030443 | Biomed Pharmacother (2020 Jun) | 32114358 | 2020 |
A facile, sensitive and rapid sensing platform based on CoZnO for detection of fipronil; an environm ... | Kumar, Sanni; Vasylieva, Natalia; Singh, Vikrant; Hammock, Bruce; Singh, Shiv Govind | P42ES004699, R35ES030443 | Electroanalysis (2020 Sep) | 33456276 | 2020 |
A rapid and simple fluorescence enzyme-linked immunosorbent assay for tetrabromobisphenol A in soil ... | Fu, Hui-Jun; Wang, Yu; Xiao, Zhi-Li; Wang, Hong; Li, Zhen-Feng; Shen, Yu-Dong; Lei, Hong-Tao; ... | P42ES004699, R35ES030443 | Ecotoxicol Environ Saf (2020 Jan 30) | 31704326 | 2020 |
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease. | Ghosh, Anamitra; Comerota, Michele M; Wan, Debin; Chen, Fading; Propson, Nicholas E; Hwang, Su ... | P42ES004699, R35ES030443 | Sci Transl Med (2020 12 09) | 33298560 | 2020 |
An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors o ... | Samuels, Eric R; Sevrioukova, Irina F | R01ES025767 | Bioorg Med Chem (2020 03 15) | 32044230 | 2020 |
An Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Heptamer Fusion ... | Li, Zhenfeng; Wang, Yi; Vasylieva, Natalia; Wan, Debin; Yin, Zihan; Dong, Jiexian; Hammock, B ... | P42ES004699, R35ES030443 | Anal Chem (2020 07 21) | 32559059 | 2020 |
Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid met ... | Huerta-Yepez, Sara; Tirado-Rodriguez, Ana; Montecillo-Aguado, Mayra R; Yang, Jun; Hammock, Bruc ... | P42ES004699, R35ES030443 | Sci Rep (2020 May 12) | 32398692 | 2020 |
Assessment of soluble epoxide hydrolase activity in vivo: A metabolomic approach. | Stefanovski, Darko; Shih, Pei-An Betty; Hammock, Bruce D; Watanabe, Richard M; Youn, Jang H | P42ES004699, R35ES030443 | Prostaglandins Other Lipid Mediat (2020 06) | 31931080 | 2020 |
Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of ... | Burmistrov, Vladimir; Morisseau, Christophe; Karlov, Dmitry; Pitushkin, Dmitry; Vernigora, Andr ... | P42ES004699, R35ES030443 | Bioorg Med Chem Lett (2020 09 15) | 32736212 | 2020 |
Chemiluminescent Enzyme Immunoassay and Bioluminescent Enzyme Immunoassay for Tenuazonic Acid Mycoto ... | Wang, Feng; Li, Zhen-Feng; Yang, Yuan-Yuan; Wan, De-Bin; Vasylieva, Natalia; Zhang, Yu-Qi; Cai ... | P42ES004699, R35ES030443 | Anal Chem (2020 Sep 01) | 32702970 | 2020 |
Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine ... | Pressly, Brandon; Vasylieva, Natalia; Barnych, Bogdan; Singh, Vikrant; Singh, Latika; Bruun, D ... | R35ES030443 | Arch Toxicol (2020 06) | 32239239 | 2020 |
Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies. | Hildreth, Kelsey; Kodani, Sean D; Hammock, Bruce D; Zhao, Ling | P42ES004699, R35ES030443 | J Nutr Biochem (2020 12) | 32827665 | 2020 |
Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrol ... | Li, Dongyang; Cui, Yongliang; Morisseau, Christophe; Wagner, Karen M; Cho, Young Sik; Hammock, ... | P42ES004699, R35ES030443 | Anal Chem (2020 09 01) | 32786492 | 2020 |
Development of a nanobody tagged with streptavidin-binding peptide and its application in a Luminex ... | Chen, Qi; Sun, Danyang; Pei, Hua; Su, Benchao; Bao, Kunlu; Cao, Hongmei; Zhang, Chenghui; Ham ... | P42ES004699, R35ES030443 | RSC Adv (2020 Jun 19) | 35517360 | 2020 |
Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detectio ... | Li, Dongyang; Morisseau, Christophe; McReynolds, Cindy B; Duflot, Thomas; Bellien, Jérémy; Nagr ... | P42ES004699, R35ES030443 | Anal Chem (2020 05 19) | 32253910 | 2020 |
Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evalu ... | Wilt, Stephanie; Kodani, Sean; Le, Thanh N H; Nguyen, Lato; Vo, Nghi; Ly, Tanya; Rodriguez, M ... | P42ES004699, R35ES030443 | Bioorg Chem (2020 10) | 32891856 | 2020 |
Development of potent inhibitors of the human microsomal epoxide hydrolase. | Barnych, Bogdan; Singh, Nalin; Negrel, Sophie; Zhang, Yue; Magis, Damien; Roux, Capucine; Hua, ... | P42ES004699, R35ES030443 | Eur J Med Chem (2020 May 01) | 32203787 | 2020 |
Early antihypertensive treatment and ischemia-induced acute kidney injury. | Greite, Robert; Derlin, Katja; Hensen, Bennet; Thorenz, Anja; Rong, Song; Chen, Rongjun; Hellm ... | R35ES030443 | Am J Physiol Renal Physiol (2020 10 01) | 32799675 | 2020 |
Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors. | Imig, John D; Morisseau, Christophe | R35ES030443 | Front Pharmacol (2020) | 33071800 | 2020 |
Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in I ... | Xie, Minhao; Yang, Jun; Zhang, Jianan; Sherman, Heather L; Zhang, Zhenyu; Minter, Lisa M; Hamm ... | P42ES004699, R35ES030443 | J Agric Food Chem (2020 Jul 22) | 32594738 | 2020 |
Eicosanoids: The Overlooked Storm in Coronavirus Disease 2019 (COVID-19)? | Hammock, Bruce D; Wang, Weicang; Gilligan, Molly M; Panigrahy, Dipak | P42ES004699, R35ES030443 | Am J Pathol (2020 09) | 32650004 | 2020 |
Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. | Coarfa, Cristian; Grimm, Sandra L; Katz, Tiffany; Zhang, Yuhao; Jangid, Rahul K; Walker, Chery ... | P30ES030285, P42ES027725, R01ES029382 | Redox Biol (2020 10) | 32961439 | 2020 |
EpOMEs act as immune suppressors in a lepidopteran insect, Spodoptera exigua. | Vatanparast, Mohammad; Ahmed, Shabbir; Lee, Dong-Hee; Hwang, Sung Hee; Hammock, Bruce; Kim, Yo ... | R35ES030443 | Sci Rep (2020 11 19) | 33214688 | 2020 |
Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indi ... | McReynolds, Cindy; Morisseau, Christophe; Wagner, Karen; Hammock, Bruce | P42ES004699, R35ES030443 | Adv Exp Med Biol (2020) | 32894508 | 2020 |
Imidazolidine-2,4,5- and pirimidine-2,4,6-triones - New primary pharmacophore for soluble epoxide hy ... | Burmistrov, Vladimir; Morisseau, Christophe; D'yachenko, Vladimir; Karlov, Dmitry; Butov, Genna ... | P42ES004699, R35ES030443 | Bioorg Med Chem Lett (2020 Feb 01) | 31870649 | 2020 |
Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major ps ... | Zhang, Jiancheng; Tan, Yunfei; Chang, Lijia; Hammock, Bruce D; Hashimoto, Kenji | P42ES004699, R35ES030443 | J Affect Disord (2020 06 01) | 32339103 | 2020 |
Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? | Panigrahy, Dipak; Gilligan, Molly M; Huang, Sui; Gartung, Allison; Cortés-Puch, Irene; Sime, P ... | P42ES004699, R35ES030443 | Cancer Metastasis Rev (2020 06) | 32385712 | 2020 |
Macromolecular modeling and design in Rosetta: recent methods and frameworks. | Leman, Julia Koehler; Weitzner, Brian D; Lewis, Steven M; Adolf-Bryfogle, Jared; Alam, Nawsad; ... | P42ES004699, R35ES030443 | Nat Methods (2020 Jul) | 32483333 | 2020 |
Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression ... | Pu, Yaoyu; Yang, Jun; Chang, Lijia; Qu, Youge; Wang, Siming; Zhang, Kai; Xiong, Zhongwei; Zha ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2020 05 26) | 32398374 | 2020 |
Molecular role of cytochrome P4501A enzymes inoxidative stress. | Stading, Rachel; Chu, Chun; Couroucli, Xanthi; Lingappan, Krithika; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Curr Opin Toxicol (2020) | 33283080 | 2020 |
N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Ep ... | Singh, Nalin; Barnych, Bogdan; Morisseau, Christophe; Wagner, Karen M; Wan, Debin; Takeshita, ... | P42ES004699, R35ES030443 | J Nat Prod (2020 Dec 24) | 33320645 | 2020 |
Novel metabolomic method to assess the effect-based removal efficiency of advanced wastewater treatm ... | Späth, Jana; Nording, Malin; Lindberg, Richard; Brodin, Tomas; Jansson, Stina; Yang, Jun; Wan, ... | P42ES004699, R35ES030443 | Environ Chem (2020) | 33692653 | 2020 |
Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-ind ... | Callaway, Danielle A; Jiang, Weiwu; Wang, Lihua; Lingappan, Krithika; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Free Radic Biol Med (2020 11 20) | 32791187 | 2020 |
Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin ... | Teixeira, Juliana Maia; Abdalla, Henrique Ballassini; Basting, Rosanna Tarkany; Hammock, Bruce D ... | P42ES004699, R35ES030443 | Int Immunopharmacol (2020 Oct) | 32736189 | 2020 |
Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease. | Griñán-Ferré, Christian; Codony, Sandra; Pujol, Eugènia; Yang, Jun; Leiva, Rosana; Escolano, C ... | P42ES004699, R35ES030443 | Neurotherapeutics (2020 Oct) | 32488482 | 2020 |
Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A ... | Gastelum, Grady; Jiang, Weiwu; Wang, Lihua; Zhou, Guodong; Borkar, Roshan; Putluri, Nagireddy; ... | P42ES027725, R01ES029382 | Toxicol Sci (2020 Oct 01) | 32726451 | 2020 |
Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and he ... | Tao, Gabriel; Huang, Junqing; Moorthy, Bhagavatula; Wang, Cathryn; Hu, Ming; Gao, Song; Ghose, ... | P30ES030285, P42ES027725, R01ES029382 | Expert Opin Drug Metab Toxicol (2020 Nov) | 32841068 | 2020 |
Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties ... | Lee, Kin Sing Stephen; Ng, Jen C; Yang, Jun; Hwang, Sung-Hee; Morisseau, Christophe; Wagner, K ... | P42ES004699, R35ES030443 | Bioorg Med Chem (2020 11 15) | 33007552 | 2020 |
Production of a specific monoclonal antibody for 1-naphthol based on novel hapten strategy and devel ... | Chen, Zi-Jian; Liu, Xi-Xia; Xiao, Zhi-Li; Fu, Hui-Jun; Huang, Yu-Ping; Huang, Shu-Yi; Shen, Y ... | P42ES004699, R35ES030443 | Ecotoxicol Environ Saf (2020 Jun 15) | 32247241 | 2020 |
Protostane-type triterpenoids as natural soluble epoxide hydrolase inhibitors: Inhibition potentials ... | Sun, Cheng-Peng; Zhang, Juan; Zhao, Wen-Yu; Yi, Jing; Yan, Jian-Kun; Wang, Ya-Li; Morisseau, ... | P42ES004699, R35ES030443 | Bioorg Chem (2020 03) | 32032849 | 2020 |
PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 infla ... | Sun, Chen-Chen; Zhang, Chen-Yu; Duan, Jia-Xi; Guan, Xin-Xin; Yang, Hui-Hui; Jiang, Hui-Ling; H ... | P42ES004699, R35ES030443 | Biochem Biophys Res Commun (2020 03 19) | 31973813 | 2020 |
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellula ... | Fishbein, Anna; Wang, Weicang; Yang, Haixia; Yang, Jun; Hallisey, Victoria M; Deng, Jianjun; V ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2020 09 01) | 32801214 | 2020 |
Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine. | Shihadih, Diyala S; Harris, Todd R; Kodani, Sean D; Hwang, Sung-Hee; Lee, Kin Sing Stephen; Mav ... | P42ES004699, R35ES030443 | Front Vet Sci (2020) | 33005645 | 2020 |
Sensitive Immunochromatographic Assay Using Highly Luminescent Quantum Dot Nanobeads as Tracer for t ... | Li, Pan; Yang, Cuifeng; Liu, Beibei; Wu, Qin; Wang, Yulong; Dong, Sa; Zhang, Hanxiaoya; Vasyl ... | P42ES004699, R35ES030443 | Front Chem (2020) | 32760698 | 2020 |
Simultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for T ... | Wu, Nan; Hammock, Bruce D; Lee, Kin Sing Stephen; An, Guohua | P42ES004699, R35ES030443 | J Pharmacol Exp Ther (2020 07) | 32238455 | 2020 |
Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglyc ... | Overby, Haley; Yang, Yang; Xu, Xinyun; Graham, Katherine; Hildreth, Kelsey; Choi, Sue; Wan, D ... | P42ES004699, R35ES030443 | Int J Mol Sci (2020 Sep 24) | 32987880 | 2020 |
Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis mode ... | Trindade-da-Silva, Carlos A; Clemente-Napimoga, Juliana T; Abdalla, Henrique B; Rosa, Sergio Mar ... | P42ES004699, R35ES030443 | FASEB J (2020 07) | 32400048 | 2020 |
Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfuncti ... | Wang, Yuxin; Yang, Jun; Wang, Weicang; Sanidad, Katherine Z; Cinelli, Maris A; Wan, Debin; Hwa ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2020 04 14) | 32220957 | 2020 |
Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain. | Wagner, Karen M; Gomes, Aldrin; McReynolds, Cindy B; Hammock, Bruce D | P42ES004699, R35ES030443 | Neurotherapeutics (2020 Jul) | 32875445 | 2020 |
Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac ... | Sirish, Padmini; Thai, Phung N; Lee, Jeong Han; Yang, Jun; Zhang, Xiao-Dong; Ren, Lu; Li, Nin ... | P42ES004699, R35ES030443 | Stem Cells Transl Med (2020 Dec) | 32790136 | 2020 |
Unexpected Differences between Two Closely Related Bacterial P450 Camphor Monooxygenases. | Murarka, Vidhi C; Batabyal, Dipanwita; Amaya, Jose A; Sevrioukova, Irina F; Poulos, Thomas L | R01ES025767 | Biochemistry (2020 07 28) | 32551522 | 2020 |
Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discove ... | Brighty, Gabriel J; Botham, Rachel C; Li, Suhua; Nelson, Luke; Mortenson, David E; Li, Genchen ... | P42ES004699, R35ES030443 | Nat Chem (2020 10) | 32868886 | 2020 |
Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Ar ... | Edin, Matthew L; Lih, Fred B; Hammock, Bruce D; Thomson, Scott; Zeldin, Darryl C; Bishop-Bailey ... | P42ES004699, R35ES030443 | Cells (2020 Apr 29) | 32365470 | 2020 |
Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish. | Knuth, Megan M; Mahapatra, Debabrata; Jima, Dereje; Wan, Debin; Hammock, Bruce D; Law, Mac; Ku ... | P30ES025128, P42ES004699, R35ES030443, T32ES007046 | Sci Rep (2020 Sep 29) | 32994480 | 2020 |
ω-3 Polyunsaturated Fatty Acids on Colonic Inflammation and Colon Cancer: Roles of Lipid-Metabolizin ... | Tu, Maolin; Wang, Weicang; Zhang, Guodong; Hammock, Bruce D | P42ES004699, R35ES030443 | Nutrients (2020 Oct 28) | 33126566 | 2020 |
1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor o ... | Liang, Zhibin; Zhang, Bei; Xu, Meng; Morisseau, Christophe; Hwang, Sung Hee; Hammock, Bruce D; ... | P42ES004699, R35ES030443 | ACS Chem Neurosci (2019 09 18) | 31378059 | 2019 |
Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epile ... | Shen, Yijun; Peng, Weifeng; Chen, Qinglan; Hammock, Bruce D; Liu, Junyan; Li, Dongyang; Yang, ... | P42ES004699, R35ES030443 | Brain Behav Immun (2019 10) | 31306773 | 2019 |
Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts f ... | Suter, Melissa A; Aagaard, Kjersti M; Coarfa, Cristian; Robertson, Matthew; Zhou, Guodong; Jack ... | P30ES030285, P42ES027725, R01ES029382 | Biochem Biophys Res Commun (2019 Aug 20) | 31208719 | 2019 |
Conformational Response of N-Terminally Truncated Cytochrome P450 3A4 to Ligand Binding in Solution. | Chuo, Shih-Wei; Liou, Shu-Hao; Wang, Lee-Ping; Britt, R David; Poulos, Thomas L; Sevrioukova, ... | R01ES025767 | Biochemistry (2019 09 17) | 31456404 | 2019 |
Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways. | Lee, Kin Sing Stephen; Yang, Jun; Niu, Jun; Ng, Connie J; Wagner, Karen M; Dong, Hua; Kodani, ... | R35ES030443 | ACS Cent Sci (2019 Sep 25) | 31572788 | 2019 |
Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation. | Dileepan, Mythili; Rastle-Simpson, Stephanie; Greenberg, Yana; Wijesinghe, Dayanjan S; Kumar, N ... | R35ES030443 | Front Pharmacol (2019) | 31611798 | 2019 |
Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic ac ... | Rand, Amy A; Rajamani, Anita; Kodani, Sean D; Harris, Todd R; Schlatt, Lukas; Barnych, Bodgan; ... | P42ES004699, R35ES030443 | J Lipid Res (2019 12) | 31641036 | 2019 |
Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules. | Sevrioukova, Irina | R01ES025767 | Biochemistry (2019 02 19) | 30676743 | 2019 |
Lung genotoxicity of benzo(a)pyrene in vivo involves reactivation of LINE-1 retrotransposon and earl ... | Hassanin, A A I; Tavera-Garcia, M; Moorthy, B; Zhou, G D; Ramos, K S | P30ES030285, P42ES027725, R01ES029382 | Am J Physiol Lung Cell Mol Physiol (2019 12 01) | 31596105 | 2019 |
Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine. | Luo, Lin; Wei, Xiao-Qun; Jia, Bao-Zhu; Yang, Jin-Yi; Shen, Yu-Dong; Hammock, Bruce; Dong, Jie ... | P42ES004699, R35ES030443 | Biomolecules (2019 10 11) | 31614550 | 2019 |
Pilot-Scale Pyrolytic Remediation of Crude-Oil-Contaminated Soil in a Continuously-Fed Reactor: Trea ... | Song, Wen; Vidonish, Julia E; Kamath, Roopa; Yu, Pingfeng; Chu, Chun; Moorthy, Bhagavatula; Ga ... | P30ES030285, P42ES027725, R01ES029382 | Environ Sci Technol (2019 02 19) | 30681845 | 2019 |
Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deox ... | Chen, Yu-Jie; Zhang, Jian; Zhu, Ping-Ping; Tan, Xian-Wen; Lin, Qiu-Hong; Wang, Wen-Xia; Yin, ... | R01ES025767 | Drug Metab Dispos (2019 06) | 30918015 | 2019 |
Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, ... | Sevrioukova, Irina F | R01ES025767 | Int J Mol Sci (2019 Aug 30) | 31480231 | 2019 |
Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group St ... | Samuels, Eric R; Sevrioukova, Irina | R01ES025767 | Biochemistry (2019 Apr 16) | 30912932 | 2019 |
Transcriptomic profiling identifies novel mechanisms of transcriptional regulation of the cytochrome ... | Taneja, Guncha; Maity, Suman; Jiang, Weiwu; Moorthy, Bhagavatula; Coarfa, Cristian; Ghose, Rom ... | P30ES030285, P42ES027725, R01ES029382 | Sci Rep (2019 Apr 30) | 31040347 | 2019 |
Direct Synthesis of α-Thio Aromatic Acids from Aromatic Amino Acids. | Samuels, Eric R; Sevrioukova, Irina | R01ES025767 | Tetrahedron Lett (2018 Mar 21) | 30140110 | 2018 |
Inhibition of Human CYP3A4 by Rationally Designed Ritonavir-Like Compounds: Impact and Interplay of ... | Samuels, Eric R; Sevrioukova, Irina | R01ES025767 | Mol Pharm (2018 Jan 02) | 29232137 | 2018 |
Steroid bioconjugation to a CYP3A4 allosteric site and its effect on substrate binding and coupling ... | Polic, Vanja; Sevrioukova, Irina F; Auclair, Karine | R01ES025767 | Arch Biochem Biophys (2018 Sep 01) | 29958895 | 2018 |
Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. | Guo, Zhijun; Sevrioukova, Irina F; Denisov, Ilia G; Zhang, Xia; Chiu, Ting-Lan; Thomas, Dafydd ... | P30ES013508, R01ES025767 | Cell Chem Biol (2017 Oct 19) | 28919040 | 2017 |
High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4. | Sevrioukova, Irina F | R01ES025767 | Biochemistry (2017 Jun 20) | 28590129 | 2017 |
Soluble Epoxide Hydrolase Inhibitor Suppresses the Expression of Triggering Receptor Expressed on My ... | Dong, Liang; Zhou, Yong; Zhu, Zhao-Qiong; Liu, Tian; Duan, Jia-Xi; Zhang, Jun; Li, Ping; Hamm ... | P42ES004699, R35ES030443 | Inflammation (2017 Feb) | 27696333 | 2017 |
Structural basis for regiospecific midazolam oxidation by human cytochrome P450 3A4. | Sevrioukova, Irina F; Poulos, Thomas L | R01ES025767 | Proc Natl Acad Sci U S A (2017 Jan 17) | 28031486 | 2017 |