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Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
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"Ready-to-use" immunosensor for the detection of small molecules with fast readout. | Ding, Yuan; Cui, Panpan; Chen, He; Li, Jiao; Huang, Lianrun; González-Sapienza, Gualberto; Ham ... | P42ES004699, R35ES030443 | Biosens Bioelectron (2022 Apr 01) |
35007993
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2022 |
A Fast and Selective Approach for Profiling Vicinal Diols Using Liquid Chromatography-Post Column De ... | Wan, Debin; Morisseau, Christophe; Hammock, Bruce D; Yang, Jun | P42ES004699, R35ES030443 | Molecules (2022 Jan 03) |
35011515
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2022 |
Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P ... | Zhou, Guodong; Jiang, Weiwu; Xia, Guobin; Wang, Lihua; Richardson, Molly; Chu, Chun; Moorthy, ... | P42ES027725, R01ES029382 | Antioxidants (Basel) (2022 Jan 05) |
35052622
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2022 |
Camelization of a murine single-domain antibody against aflatoxin B1 and its antigen-binding analysi ... | Pang, Qian; Chen, Yanhong; Mukhtar, Hina; Xiong, Jing; Wang, Xiaohong; Xu, Ting; Hammock, Bru ... | P42ES004699, R35ES030443 | Mycotoxin Res (2022 Feb) |
35023020
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2022 |
Clinical and Preclinical Evidence for Roles of Soluble Epoxide Hydrolase in Osteoarthritis Knee Pain ... | Gowler, Peter R W; Turnbull, James; Shahtaheri, Mohsen; Gohir, Sameer; Kelly, Tony; McReynolds, ... | P42ES004699, R35ES030443 | Arthritis Rheumatol (2022 04) |
34672113
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2022 |
Development of a Rapid Gold Nanoparticle Immunochromatographic Strip Based on the Nanobody for Detec ... | Zhou, Hui; He, Cong; Li, Zhenfeng; Huo, Jingqian; Xue, Yu; Xu, Xiaotong; Qi, Meng; Chen, Lai ... | P42ES004699, R35ES030443 | Biosensors (Basel) (2022 Jan 30) |
35200344
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2022 |
Fluonanobody-based nanosensor via fluorescence resonance energy transfer for ultrasensitive detectio ... | Su, Benchao; Zhang, Zhong; Sun, Zhichang; Tang, Zongwen; Xie, Xiaoxia; Chen, Qi; Cao, Hongmei ... | P42ES004699, R35ES030443 | J Hazard Mater (2022 01 15) |
34411960
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2022 |
Improved ELISA for linoleate-derived diols in human plasma utilizing a polyHRP-based secondary trace ... | Singh, Nalin; Li, Dongyang; McReynolds, Cindy B; Morisseau, Christophe; Hammock, Bruce D | P42ES004699, R35ES030443 | Anal Methods (2022 May 13) |
35481804
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2022 |
Kurarinone alleviated Parkinson's disease via stabilization of epoxyeicosatrienoic acids in animal m ... | Sun, Cheng-Peng; Zhou, Jun-Jun; Yu, Zhen-Long; Huo, Xiao-Kui; Zhang, Juan; Morisseau, Christop ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2022 03 01) |
35217618
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2022 |
Metabolism of Benzalkonium Chloride by CYP-Mediated ω-Oxidation and C-C Cleavage Followed by β-Oxida ... | Seguin, Ryan; Xu, Libin | P30ES007033, R01ES031927, T32ES007032 | FASEB J (2022 May) |
35567457
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2022 |
Phosphate-triggered ratiometric fluoroimmunoassay based on nanobody-alkaline phosphatase fusion for ... | Chen, Zi-Jian; Wu, Hui-Ling; Shen, Yu-Dong; Wang, Hong; Zhang, Yi-Feng; Hammock, Bruce; Li, Z ... | P42ES004699, R35ES030443 | J Hazard Mater (2022 02 15) |
34629198
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2022 |
sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate im ... | Bergmann, Christian B; McReynolds, Cindy B; Wan, Debin; Singh, Nalin; Goetzman, Holly; Caldwell ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2022 03 29) |
35312372
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2022 |
The Aryl Hydrocarbon Receptor (AHR): A Novel Therapeutic Target for Pulmonary Diseases? | Shivanna, Binoy; Chu, Chun; Moorthy, Bhagavatula | R01ES029382 | Int J Mol Sci (2022 Jan 28) |
35163440
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2022 |
The Role of Hydrolases in Biology and Xenobiotics Metabolism. | Morisseau, Christophe | P42ES004699, R35ES030443 | Int J Mol Sci (2022 Apr 28) |
35563260
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2022 |
2-(Piperidin-4-yl)acetamides as Potent Inhibitors of Soluble Epoxide Hydrolase with Anti-Inflammator ... | Martín-López, Juan; Codony, Sandra; Bartra, Clara; Morisseau, Christophe; Loza, María Isabel; S ... | P42ES004699, R35ES030443 | Pharmaceuticals (Basel) (2021 Dec 17) |
34959721
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2021 |
A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, ... | Jonnalagadda, Deepa; Wan, Debin; Chun, Jerold; Hammock, Bruce D; Kihara, Yasuyuki | P42ES004699, R35ES030443 | Int J Mol Sci (2021 Apr 28) |
33925035
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2021 |
Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis. | Mavangira, Vengai; Kuhn, Matthew J; Abuelo, Angel; Morisseau, Christophe; Hammock, Bruce D; Sor ... | P42ES004699, R35ES030443 | Antioxidants (Basel) (2021 May 20) |
34065244
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2021 |
Adrenic Acid-Derived Epoxy Fatty Acids Are Naturally Occurring Lipids and Their Methyl Ester Prodrug ... | Singh, Nalin; Barnych, Bogdan; Wagner, Karen M; Wan, Debin; Morisseau, Christophe; Hammock, Br ... | P42ES004699, R35ES030443 | ACS Omega (2021 Mar 16) |
33748630
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2021 |
Amphipol-facilitated elucidation of the functional tetrameric complex of full-length cytochrome P450 ... | Cheng, Shen; Bo, Zhiyuan; Hollenberg, Paul; Osawa, Yoichi; Zhang, Haoming | R21ES030791 | J Biol Chem (2021 Jan-Jun) |
33839156
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2021 |
Autism-like Behaviors in Male Juvenile Offspring after Maternal Glyphosate Exposure. | Pu, Yaoyu; Ma, Li; Shan, Jiajing; Wan, Xiayun; Hammock, Bruce D; Hashimoto, Kenji | P42ES004699, R35ES030443 | Clin Psychopharmacol Neurosci (2021 Aug 31) |
34294625
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2021 |
Carcinogenesis: Failure of resolution of inflammation? | Fishbein, Anna; Hammock, Bruce D; Serhan, Charles N; Panigrahy, Dipak | P42ES004699, R35ES030443 | Pharmacol Ther (2021 02) |
32891711
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2021 |
Chronic Diclofenac Exposure Increases Mitochondrial Oxidative Stress, Inflammatory Mediators, and Ca ... | Thai, Phung N; Ren, Lu; Xu, Wilson; Overton, James; Timofeyev, Valeriy; Nader, Carol E; Haddad ... | P42ES004699, R35ES030443 | Cardiovasc Drugs Ther (2021 Sep 09) |
34499283
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2021 |
COX-2/sEH Dual Inhibitor PTUPB Alleviates CCl 4 -Induced Liver Fibrosis and Portal Hypertension. | Zhao, Zhifeng; Zhang, Chihao; Lin, Jiayun; Zheng, Lei; Li, Hongjie; Qi, Xiaoliang; Huo, Haizh ... | P42ES004699, R35ES030443 | Front Med (Lausanne) (2021) |
35004731
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2021 |
Development of a chemiluminescence immunoassay for detection of tenuazonic acid mycotoxin in fruit j ... | Wang, Feng; Wan, De-Bin; Shen, Yu-Dong; Tian, Yuan-Xin; Xiao, Zhi-Li; Xu, Zhen-Lin; Yang, Jin ... | R35ES030443 | Anal Methods (2021 04 22) |
33885655
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2021 |
Development of a nanobody-based ELISA for the detection of the insecticides cyantraniliprole and chl ... | Xu, Bojie; Wang, Kai; Vasylieva, Natalia; Zhou, Hang; Xue, Xianle; Wang, Baomin; Li, Qing X; ... | P42ES004699, R35ES030443 | Anal Bioanal Chem (2021 Apr) |
33580830
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2021 |
Development of a sensitive non-competitive immunoassay via immunocomplex binding peptide for the det ... | Fu, Hui-Jun; Chen, Zi-Jian; Wang, Hong; Luo, Lin; Wang, Yu; Huang, Ri-Ming; Xu, Zhen-Lin; Ham ... | P42ES004699, R35ES030443 | J Hazard Mater (2021 03 15) |
33525128
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2021 |
Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t- ... | Yang, Yang; Xu, Xinyun; Wu, Haoying; Yang, Jun; Chen, Jiangang; Morisseau, Christophe; Hammock ... | P42ES004699, R35ES030443 | Int J Mol Sci (2021 Jul 31) |
34361032
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2021 |
Discovery of memantyl urea derivatives as potent soluble epoxide hydrolase inhibitors against lipopo ... | Du, Fangyu; Sun, Wenjiao; Morisseau, Christophe; Hammock, Bruce D; Bao, Xuefei; Liu, Qiu; Wang ... | P42ES004699, R35ES030443 | Eur J Med Chem (2021 Nov 05) |
34218083
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2021 |
Discovery of Soluble Epoxide Hydrolase Inhibitors from Chemical Synthesis and Natural Products. | Sun, Cheng-Peng; Zhang, Xin-Yue; Morisseau, Christophe; Hwang, Sung Hee; Zhang, Zhan-Jun; Hammo ... | P42ES004699, R35ES030443 | J Med Chem (2021 01 14) |
33369424
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2021 |
Dual sEH/COX-2 Inhibition Using PTUPB-A Promising Approach to Antiangiogenesis-Induced Nephrotoxicit ... | Jankiewicz, Wojciech K; Barnett, Scott D; Stavniichuk, Anna; Hwang, Sung Hee; Hammock, Bruce D; ... | P42ES004699, R35ES030443 | Front Pharmacol (2021) |
34955823
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2021 |
Effect of sex chromosomes versus hormones in neonatal lung injury. | Grimm, Sandra L; Dong, Xiaoyu; Zhang, Yuhao; Carisey, Alexandre F; Arnold, Arthur P; Moorthy, ... | P42ES027725, R01ES029382 | JCI Insight (2021 07 08) |
34061778
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2021 |
Eicosanoid regulation of debris-stimulated metastasis. | Deng, Jianjun; Yang, Haixia; Haak, Victoria M; Yang, Jun; Kipper, Franciele C; Barksdale, Chan ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2021 10 12) |
34607951
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2021 |
EPHX1 mutations cause a lipoatrophic diabetes syndrome due to impaired epoxide hydrolysis and increa ... | Gautheron, Jeremie; Morisseau, Christophe; Chung, Wendy K; Zammouri, Jamila; Auclair, Martine; ... | P42ES004699, R35ES030443 | Elife (2021 08 03) |
34342583
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2021 |
From the Design to the In Vivo Evaluation of Benzohomoadamantane-Derived Soluble Epoxide Hydrolase I ... | Codony, Sandra; Calvó-Tusell, Carla; Valverde, Elena; Osuna, Sílvia; Morisseau, Christophe; Loz ... | P42ES004699, R35ES030443 | J Med Chem (2021 05 13) |
33945278
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2021 |
Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty a ... | Wilt, Stephanie; Kodani, Sean; Valencia, Leah; Hudson, Paula K; Sanchez, Stephanie; Quintana, ... | P42ES004699, R35ES030443 | Bioorg Med Chem (2021 12 01) |
34794001
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2021 |
Fusion expression of nanobodies specific for the insecticide fipronil on magnetosomes in Magnetospir ... | Wu, Sha; Ma, Fengfei; He, Jinxin; Li, Qing X; Hammock, Bruce D; Tian, Jiesheng; Xu, Ting | P42ES004699, R35ES030443 | J Nanobiotechnology (2021 Jan 19) |
33468141
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2021 |
Generation of Dual functional Nanobody-Nanoluciferase Fusion and its potential in Bioluminescence En ... | Yu, Sheng; Li, Zhenfeng; Li, Jingzhang; Zhao, Shimei; Wu, Shanguang; Liu, Hongjing; Bi, Xiong ... | P42ES004699, R35ES030443 | Sens Actuators B Chem (2021 Jun 01) |
35250176
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2021 |
Genetic deficiency or pharmacological inhibition of soluble epoxide hydrolase ameliorates high fat d ... | Koike, Shinichiro; Hsu, Ming-Fo; Bettaieb, Ahmed; Chu, Bryan; Matsumoto, Naoki; Morisseau, Chr ... | P42ES004699, R35ES030443 | Free Radic Biol Med (2021 08 20) |
34038767
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2021 |
Highly specific nanobody against herbicide 2,4-dichlorophenoxyacetic acid for monitoring of its cont ... | Li, Zhen-Feng; Dong, Jie-Xian; Vasylieva, Natalia; Cui, Yong-Liang; Wan, De-Bin; Hua, Xiu-De; ... | P42ES004699, R35ES030443 | Sci Total Environ (2021 Jan 20) |
32906044
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2021 |
HIV-related Neuropathy: Pathophysiology, Treatment and Challenges. | Jazebi, Noushin; Evans, Chad; Kadaru, Hima S; Kompella, Divya; Raji, Mukaila; Fang, Felix; Pap ... | P42ES004699, R35ES030443 | J Neurol Exp Neurosci (2021) |
35252633
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2021 |
Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different ... | Tiwari, Shuchita; Yang, Jun; Morisseau, Christophe; Durbin-Johnson, Blythe; Hammock, Bruce D; G ... | P42ES004699, R35ES030443 | Sci Rep (2021 03 29) |
33782432
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2021 |
Identification of the Functional Binding Site for the Convulsant Tetramethylenedisulfotetramine in t ... | Pressly, Brandon; Lee, Ruth D; Barnych, Bogdan; Hammock, Bruce D; Wulff, Heike | R35ES030443 | Mol Pharmacol (2021 01) |
33109687
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2021 |
Increased toxicity and retention of perflourooctane sulfonate (PFOS) in humanized CYP2B6-Transgenic ... | Hamilton, Matthew C; Heintz, Melissa M; Pfohl, Marisa; Marques, Emily; Ford, Lucie; Slitt, Ang ... | P42ES027706, R15ES017321, R15ES017321 | Food Chem Toxicol (2021 Jun) |
33838175
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2021 |
Ingestion of Faecalibaculum rodentium causes depression-like phenotypes in resilient Ephx2 knock-out ... | Wang, Siming; Ishima, Tamaki; Qu, Youge; Shan, Jiajing; Chang, Lijia; Wei, Yan; Zhang, Jianch ... | P42ES004699, R35ES030443 | J Affect Disord (2021 09 01) |
34147969
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2021 |
Inhibition of sEH via stabilizing the level of EETs alleviated Alzheimer's disease through GSK3β sig ... | Sun, Cheng-Peng; Zhang, Xin-Yue; Zhou, Jun-Jun; Huo, Xiao-Kui; Yu, Zhen-Long; Morisseau, Chris ... | P42ES004699, R35ES030443 | Food Chem Toxicol (2021 Oct) |
34411643
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2021 |
Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Eviden ... | Wang, Yuxin; Wagner, Karen M; Morisseau, Christophe; Hammock, Bruce D | R35ES030443 | J Pain Res (2021) |
33488116
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2021 |
Innovative C2-symmetric testosterone and androstenedione dimers: Design, synthesis, biological evalu ... | Paquin, Alexis; Oufqir, Yassine; Sevrioukova, Irina F; Reyes-Moreno, Carlos; Bérubé, Gervais | R01ES025767 | Eur J Med Chem (2021 Aug 05) |
33933755
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2021 |
Molecular docking-guided synthesis of NSAID-glucosamine bioconjugates and their evaluation as COX-1/ ... | Jones Lipinski, Rachel A; Thillier, Yann; Morisseau, Christophe; Sebastiano Jr, Christopher S; S ... | R35ES030443 | Chem Biol Drug Des (2021 07) |
33955172
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2021 |
Molecular mechanisms of pulmonary carcinogenesis by polycyclic aromatic hydrocarbons (PAHs): Implica ... | Stading, Rachel; Gastelum, Grady; Chu, Chun; Jiang, Weiwu; Moorthy, Bhagavatula | P42ES027725, R01ES029382, R21ES032739 | Semin Cancer Biol (2021 11) |
34242741
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2021 |
Multitarget molecule, PTUPB, to treat diabetic nephropathy in rats. | Khan, Md Abdul Hye; Hwang, Sung Hee; Barnett, Scott D; Stavniichuk, Anna; Jankiewicz, Wojciech ... | R35ES030443 | Br J Pharmacol (2021 11) |
34255857
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2021 |
Nanobody-based chimeric antigen receptor T cells designed by CRISPR/Cas9 technology for solid tumor ... | Mo, Fengzhen; Duan, Siliang; Jiang, Xiaobing; Yang, Xiaomei; Hou, Xiaoqiong; Shi, Wei; Carlos, ... | P42ES004699, R35ES030443 | Signal Transduct Target Ther (2021 02 25) |
33627635
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2021 |
New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via R ... | Singh, Nalin; Vik, Anders; Lybrand, Daniel B; Morisseau, Christophe; Hammock, Bruce D | P42ES004699, R35ES030443 | Chem Res Toxicol (2021 12 20) |
34817988
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2021 |
Nutrition, one-carbon metabolism and arsenic methylation. | Abuawad, Ahlam; Bozack, Anne K; Saxena, Roheeni; Gamble, Mary V | F31ES032321, P30ES009089, R01ES030945, R01ES030945 | Toxicology (2021 06 15) |
33905762
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2021 |
Pharmacokinetics, Metabolite Measurement and Biomarker Identification of Dermal Exposure to Permethr ... | Buchholz, Bruce A; Ahn, KiChang; Huang, Huazhang; Gee, Shirley J; Stewart, Benjamin; Ognibene, ... | P42ES004699, R35ES030443 | Toxicol Sci (2021 Jun 21) |
34152416
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2021 |
Pharmacokinetics, Metabolite Measurement, and Biomarker Identification of Dermal Exposure to Permeth ... | Buchholz, Bruce A; Ahn, Ki Chang; Huang, Huazhang; Gee, Shirley J; Stewart, Benjamin J; Ogniben ... | P42ES004699, R35ES030443 | Toxicol Sci (2021 08 30) |
34460930
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2021 |
Photosensitive Ru(II) Complexes as Inhibitors of the Major Human Drug Metabolizing Enzyme CYP3A4. | Toupin, Nicholas; Steinke, Sean J; Nadella, Sandeep; Li, Ao; Rohrabaugh Jr, Thomas N; Samuels, ... | R01ES025767 | J Am Chem Soc (2021 06 23) |
34110801
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2021 |
Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections. | McReynolds, Cindy B; Cortes-Puch, Irene; Ravindran, Resmi; Khan, Imran H; Hammock, Bruce G; Shi ... | P42ES004699, R35ES030443 | Front Physiol (2021) |
33868029
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2021 |
Preservation of epoxyeicosatrienoic acid bioavailability prevents renal allograft dysfunction and ca ... | Duflot, Thomas; Laurent, Charlotte; Soudey, Anne; Fonrose, Xavier; Hamzaoui, Mouad; Iacob, Mic ... | P42ES004699, R35ES030443 | Sci Rep (2021 02 12) |
33580125
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2021 |
Rational Design of CYP3A4 Inhibitors: A One-Atom Linker Elongation in Ritonavir-Like Compounds Leads ... | Samuels, Eric R; Sevrioukova, Irina F | R01ES025767 | Int J Mol Sci (2021 Jan 16) |
33467005
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2021 |
Relative Importance of Soluble and Microsomal Epoxide Hydrolases for the Hydrolysis of Epoxy-Fatty A ... | Morisseau, Christophe; Kodani, Sean D; Kamita, Shizuo G; Yang, Jun; Lee, Kin Sing Stephen; Hamm ... | P42ES004699, R35ES030443 | Int J Mol Sci (2021 May 08) |
34066758
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2021 |
Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative D ... | Burke, Rebecca; Chu, Chun; Zhou, Guo-Dong; Putluri, Vasanta; Putluri, Nagireddy; Stading, Rach ... | P42ES027725, R01ES029382 | Oxid Med Cell Longev (2021) |
34691356
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2021 |
Sex-Specific Differences in Resolution of Airway Inflammation in Fat-1 Transgenic Mice Following Rep ... | Ulu, Arzu; Velazquez, Jalene V; Burr, Abigail; Sveiven, Stefanie N; Yang, Jun; Bravo, Carissa; ... | P42ES004699, R35ES030443 | Front Pharmacol (2021) |
35095496
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2021 |
Smartphone-Based Dual-Channel Immunochromatographic Test Strip with Polymer Quantum Dot Labels for S ... | Zhao, Yuting; Ruan, Xiaofan; Song, Yang; Smith, Jordan N; Vasylieva, Natalia; Hammock, Bruce D ... | P42ES004699, R35ES030443 | Anal Chem (2021 10 12) |
34591463
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2021 |
Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mT ... | Wang, Luyun; Zhao, Daqiang; Tang, Liangqiu; Li, Huihui; Liu, Zhaoyu; Gao, Jingwei; Edin, Matt ... | P42ES004699, R35ES030443 | J Mol Cell Cardiol (2021 05) |
33378686
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2021 |
Soluble Epoxide Hydrolase Deletion Limits High-Fat Diet-Induced Inflammation. | Wagner, Karen M; Yang, Jun; Morisseau, Christophe; Hammock, Bruce D | P42ES004699, R35ES030443 | Front Pharmacol (2021) |
34975481
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2021 |
Soluble Epoxide Hydrolase Hepatic Deficiency Ameliorates Alcohol-Associated Liver Disease. | Mello, Aline; Hsu, Ming-Fo; Koike, Shinichiro; Chu, Bryan; Cheng, Jeff; Yang, Jun; Morisseau, ... | P42ES004699, R35ES030443 | Cell Mol Gastroenterol Hepatol (2021) |
33068774
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2021 |
Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury. | Jamieson, K Lockhart; Darwesh, Ahmed M; Sosnowski, Deanna K; Zhang, Hao; Shah, Saumya; Zhabyeye ... | P42ES004699, R35ES030443 | Int J Mol Sci (2021 Feb 08) |
33567578
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2021 |
Soluble epoxide hydrolase inhibition improves cognitive function and parenchymal artery dilation in ... | Matin, Nusrat; Fisher, Courtney; Lansdell, Theresa A; Hammock, Bruce D; Yang, Jun; Jackson, Wi ... | P42ES004699, R35ES030443 | Microcirculation (2021 01) |
32767848
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2021 |
Sortase-Mediated Phage Decoration for Analytical Applications. | Ding, Yuan; Chen, He; Li, Jiao; Huang, Lianrun; Song, Guangyue; Li, Zhenfeng; Hua, Xiude; Gon ... | P42ES004699, R35ES030443 | Anal Chem (2021 08 31) |
34415158
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2021 |
Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Impo ... | McReynolds, Cindy B; Yang, Jun; Guedes, Alonso; Morisseau, Christophe; Garcia, Roberto; Knych, ... | P42ES004699, R35ES030443 | Molecules (2021 Aug 19) |
34443621
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2021 |
Structural Basis for the Diminished Ligand Binding and Catalytic Ability of Human Fetal-Specific CYP ... | Sevrioukova, Irina F | R01ES025767 | Int J Mol Sci (2021 May 29) |
34072457
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2021 |
Structural Dynamics of Cytochrome P450 3A4 in the Presence of Substrates and Cytochrome P450 Reducta ... | Ducharme, Julie; Sevrioukova, Irina F; Thibodeaux, Christopher J; Auclair, Karine | R01ES025767 | Biochemistry (2021 07 20) |
34196520
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2021 |
Target-Mediated Drug Disposition-A Class Effect of Soluble Epoxide Hydrolase Inhibitors. | An, Guohua; Lee, Kin Sing Stephen; Yang, Jun; Hammock, Bruce D | P42ES004699, R35ES030443 | J Clin Pharmacol (2021 04) |
33078430
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2021 |
The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury. | Stading, Rachel; Couroucli, Xanthi; Lingappan, Krithika; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Expert Opin Drug Metab Toxicol (2021 Feb) |
33215946
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2021 |
TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs ne ... | Bergmann, Christian B; Hammock, Bruce D; Wan, Debin; Gogolla, Falk; Goetzman, Holly; Caldwell, ... | P42ES004699, R35ES030443 | Sci Rep (2021 08 16) |
34400718
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2021 |
1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), a soluble epoxide hydrolase inhi ... | Bukhari, I A; Alorainey, B I; Al-Motrefi, A A; Mahmoud, A; Campbell, W B; Hammock, B D | P42ES004699, R35ES030443 | Eur Rev Med Pharmacol Sci (2020 08) |
32767352
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2020 |
2-Oxaadamant-1-yl Ureas as Soluble Epoxide Hydrolase Inhibitors: In Vivo Evaluation in a Murine Mode ... | Codony, Sandra; Pujol, Eugènia; Pizarro, Javier; Feixas, Ferran; Valverde, Elena; Loza, M Isab ... | P42ES004699, R35ES030443 | J Med Chem (2020 09 10) |
32787085
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2020 |
A COX-2/sEH dual inhibitor PTUPB ameliorates cecal ligation and puncture-induced sepsis in mice via ... | Zhang, Yan-Feng; Sun, Chen-Chen; Duan, Jia-Xi; Yang, Hui-Hui; Zhang, Chen-Yu; Xiong, Jian-Bing ... | P42ES004699, R35ES030443 | Biomed Pharmacother (2020 Jun) |
32114358
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2020 |
A facile, sensitive and rapid sensing platform based on CoZnO for detection of fipronil; an environm ... | Kumar, Sanni; Vasylieva, Natalia; Singh, Vikrant; Hammock, Bruce; Singh, Shiv Govind | P42ES004699, R35ES030443 | Electroanalysis (2020 Sep) |
33456276
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2020 |
A rapid and simple fluorescence enzyme-linked immunosorbent assay for tetrabromobisphenol A in soil ... | Fu, Hui-Jun; Wang, Yu; Xiao, Zhi-Li; Wang, Hong; Li, Zhen-Feng; Shen, Yu-Dong; Lei, Hong-Tao; ... | P42ES004699, R35ES030443 | Ecotoxicol Environ Saf (2020 Jan 30) |
31704326
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2020 |
An epoxide hydrolase inhibitor reduces neuroinflammation in a mouse model of Alzheimer's disease. | Ghosh, Anamitra; Comerota, Michele M; Wan, Debin; Chen, Fading; Propson, Nicholas E; Hwang, Su ... | P42ES004699, R35ES030443 | Sci Transl Med (2020 12 09) |
33298560
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2020 |
An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors o ... | Samuels, Eric R; Sevrioukova, Irina F | R01ES025767 | Bioorg Med Chem (2020 03 15) |
32044230
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2020 |
An Ultrasensitive Bioluminescent Enzyme Immunoassay Based on Nanobody/Nanoluciferase Heptamer Fusion ... | Li, Zhenfeng; Wang, Yi; Vasylieva, Natalia; Wan, Debin; Yin, Zihan; Dong, Jiexian; Hammock, B ... | P42ES004699, R35ES030443 | Anal Chem (2020 07 21) |
32559059
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2020 |
Aryl Hydrocarbon Receptor-Dependent inductions of omega-3 and omega-6 polyunsaturated fatty acid met ... | Huerta-Yepez, Sara; Tirado-Rodriguez, Ana; Montecillo-Aguado, Mayra R; Yang, Jun; Hammock, Bruc ... | P42ES004699, R35ES030443 | Sci Rep (2020 05 12) |
32398692
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2020 |
Assessment of soluble epoxide hydrolase activity in vivo: A metabolomic approach. | Stefanovski, Darko; Shih, Pei-An Betty; Hammock, Bruce D; Watanabe, Richard M; Youn, Jang H | P42ES004699, R35ES030443 | Prostaglandins Other Lipid Mediat (2020 06) |
31931080
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2020 |
Bioisosteric substitution of adamantane with bicyclic lipophilic groups improves water solubility of ... | Burmistrov, Vladimir; Morisseau, Christophe; Karlov, Dmitry; Pitushkin, Dmitry; Vernigora, Andr ... | P42ES004699, R35ES030443 | Bioorg Med Chem Lett (2020 09 15) |
32736212
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2020 |
Chemiluminescent Enzyme Immunoassay and Bioluminescent Enzyme Immunoassay for Tenuazonic Acid Mycoto ... | Wang, Feng; Li, Zhen-Feng; Yang, Yuan-Yuan; Wan, De-Bin; Vasylieva, Natalia; Zhang, Yu-Qi; Cai ... | P42ES004699, R35ES030443 | Anal Chem (2020 09 01) |
32702970
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2020 |
Comparison of the toxicokinetics of the convulsants picrotoxinin and tetramethylenedisulfotetramine ... | Pressly, Brandon; Vasylieva, Natalia; Barnych, Bogdan; Singh, Vikrant; Singh, Latika; Bruun, D ... | R35ES030443 | Arch Toxicol (2020 06) |
32239239
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2020 |
Cryo-EM reveals the architecture of the dimeric cytochrome P450 CYP102A1 enzyme and conformational c ... | Su, Min; Chakraborty, Sumita; Osawa, Yoichi; Zhang, Haoming | R21ES030791 | J Biol Chem (2020 02 07) |
31901079
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2020 |
Cytochrome P450-derived linoleic acid metabolites EpOMEs and DiHOMEs: a review of recent studies. | Hildreth, Kelsey; Kodani, Sean D; Hammock, Bruce D; Zhao, Ling | P42ES004699, R35ES030443 | J Nutr Biochem (2020 12) |
32827665
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2020 |
Development of a Highly Sensitive Enzyme-Linked Immunosorbent Assay for Mouse Soluble Epoxide Hydrol ... | Li, Dongyang; Cui, Yongliang; Morisseau, Christophe; Wagner, Karen M; Cho, Young Sik; Hammock, ... | P42ES004699, R35ES030443 | Anal Chem (2020 09 01) |
32786492
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2020 |
Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detectio ... | Li, Dongyang; Morisseau, Christophe; McReynolds, Cindy B; Duflot, Thomas; Bellien, Jérémy; Nagr ... | P42ES004699, R35ES030443 | Anal Chem (2020 05 19) |
32253910
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2020 |
Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evalu ... | Wilt, Stephanie; Kodani, Sean; Le, Thanh N H; Nguyen, Lato; Vo, Nghi; Ly, Tanya; Rodriguez, M ... | P42ES004699, R35ES030443 | Bioorg Chem (2020 10) |
32891856
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2020 |
Development of potent inhibitors of the human microsomal epoxide hydrolase. | Barnych, Bogdan; Singh, Nalin; Negrel, Sophie; Zhang, Yue; Magis, Damien; Roux, Capucine; Hua, ... | P42ES004699, R35ES030443 | Eur J Med Chem (2020 May 01) |
32203787
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2020 |
Early antihypertensive treatment and ischemia-induced acute kidney injury. | Greite, Robert; Derlin, Katja; Hensen, Bennet; Thorenz, Anja; Rong, Song; Chen, Rongjun; Hellm ... | R35ES030443 | Am J Physiol Renal Physiol (2020 10 01) |
32799675
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2020 |
Editorial: Clinical Paths for Soluble Epoxide Hydrolase Inhibitors. | Imig, John D; Morisseau, Christophe | R35ES030443 | Front Pharmacol (2020) |
33071800
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2020 |
Effects of Linoleic Acid-Rich Diet on Plasma Profiles of Eicosanoids and Development of Colitis in I ... | Xie, Minhao; Yang, Jun; Zhang, Jianan; Sherman, Heather L; Zhang, Zhenyu; Minter, Lisa M; Hamm ... | P42ES004699, R35ES030443 | J Agric Food Chem (2020 Jul 22) |
32594738
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2020 |
Eicosanoids: The Overlooked Storm in Coronavirus Disease 2019 (COVID-19)? | Hammock, Bruce D; Wang, Weicang; Gilligan, Molly M; Panigrahy, Dipak | P42ES004699, R35ES030443 | Am J Pathol (2020 09) |
32650004
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2020 |
Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. | Coarfa, Cristian; Grimm, Sandra L; Katz, Tiffany; Zhang, Yuhao; Jangid, Rahul K; Walker, Chery ... | P42ES027725, R01ES029382 | Redox Biol (2020 10) |
32961439
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2020 |
EpOMEs act as immune suppressors in a lepidopteran insect, Spodoptera exigua. | Vatanparast, Mohammad; Ahmed, Shabbir; Lee, Dong-Hee; Hwang, Sung Hee; Hammock, Bruce; Kim, Yo ... | R35ES030443 | Sci Rep (2020 11 19) |
33214688
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2020 |
Epoxy Fatty Acids Are Promising Targets for Treatment of Pain, Cardiovascular Disease and Other Indi ... | McReynolds, Cindy; Morisseau, Christophe; Wagner, Karen; Hammock, Bruce | P42ES004699, R35ES030443 | Adv Exp Med Biol (2020) |
32894508
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2020 |
Gender differences in diet-induced steatotic disease in Cyp2b-null mice. | Heintz, Melissa M; McRee, Rebecca; Kumar, Ramiya; Baldwin, William S | R15ES017321, R15ES017321 | PLoS One (2020) |
32155178
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2020 |
Imidazolidine-2,4,5- and pirimidine-2,4,6-triones - New primary pharmacophore for soluble epoxide hy ... | Burmistrov, Vladimir; Morisseau, Christophe; D'yachenko, Vladimir; Karlov, Dmitry; Butov, Genna ... | P42ES004699, R35ES030443 | Bioorg Med Chem Lett (2020 02 01) |
31870649
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2020 |
Increased expression of soluble epoxide hydrolase in the brain and liver from patients with major ps ... | Zhang, Jiancheng; Tan, Yunfei; Chang, Lijia; Hammock, Bruce D; Hashimoto, Kenji | P42ES004699, R35ES030443 | J Affect Disord (2020 06 01) |
32339103
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2020 |
Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19? | Panigrahy, Dipak; Gilligan, Molly M; Huang, Sui; Gartung, Allison; Cortés-Puch, Irene; Sime, P ... | P42ES004699, R35ES030443 | Cancer Metastasis Rev (2020 06) |
32385712
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2020 |
Macromolecular modeling and design in Rosetta: recent methods and frameworks. | Leman, Julia Koehler; Weitzner, Brian D; Lewis, Steven M; Adolf-Bryfogle, Jared; Alam, Nawsad; ... | P42ES004699, R35ES030443 | Nat Methods (2020 07) |
32483333
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2020 |
Maternal glyphosate exposure causes autism-like behaviors in offspring through increased expression ... | Pu, Yaoyu; Yang, Jun; Chang, Lijia; Qu, Youge; Wang, Siming; Zhang, Kai; Xiong, Zhongwei; Zha ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2020 05 26) |
32398374
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2020 |
Molecular role of cytochrome P4501A enzymes inoxidative stress. | Stading, Rachel; Chu, Chun; Couroucli, Xanthi; Lingappan, Krithika; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Curr Opin Toxicol (2020 Apr-Jun) |
33283080
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2020 |
N-Benzyl-linoleamide, a Constituent of Lepidium meyenii (Maca), Is an Orally Bioavailable Soluble Ep ... | Singh, Nalin; Barnych, Bogdan; Morisseau, Christophe; Wagner, Karen M; Wan, Debin; Takeshita, ... | P42ES004699, R35ES030443 | J Nat Prod (2020 12 24) |
33320645
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2020 |
Novel metabolomic method to assess the effect-based removal efficiency of advanced wastewater treatm ... | Späth, Jana; Nording, Malin; Lindberg, Richard; Brodin, Tomas; Jansson, Stina; Yang, Jun; Wan, ... | P42ES004699, R35ES030443 | Environ Chem (2020) |
33692653
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2020 |
Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-ind ... | Callaway, Danielle A; Jiang, Weiwu; Wang, Lihua; Lingappan, Krithika; Moorthy, Bhagavatula | P42ES027725, R01ES029382 | Free Radic Biol Med (2020 11 20) |
32791187
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2020 |
Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin ... | Teixeira, Juliana Maia; Abdalla, Henrique Ballassini; Basting, Rosanna Tarkany; Hammock, Bruce D ... | P42ES004699, R35ES030443 | Int Immunopharmacol (2020 Oct) |
32736189
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2020 |
Pharmacological Inhibition of Soluble Epoxide Hydrolase as a New Therapy for Alzheimer's Disease. | Griñán-Ferré, Christian; Codony, Sandra; Pujol, Eugènia; Yang, Jun; Leiva, Rosana; Escolano, C ... | P42ES004699, R35ES030443 | Neurotherapeutics (2020 10) |
32488482
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2020 |
Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A ... | Gastelum, Grady; Jiang, Weiwu; Wang, Lihua; Zhou, Guodong; Borkar, Roshan; Putluri, Nagireddy; ... | P42ES027725, R01ES029382 | Toxicol Sci (2020 10 01) |
32726451
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2020 |
Potential role of drug metabolizing enzymes in chemotherapy-induced gastrointestinal toxicity and he ... | Tao, Gabriel; Huang, Junqing; Moorthy, Bhagavatula; Wang, Cathryn; Hu, Ming; Gao, Song; Ghose, ... | P42ES027725, R01ES029382 | Expert Opin Drug Metab Toxicol (2020 Nov) |
32841068
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2020 |
Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties ... | Lee, Kin Sing Stephen; Ng, Jen C; Yang, Jun; Hwang, Sung-Hee; Morisseau, Christophe; Wagner, K ... | P42ES004699, R35ES030443 | Bioorg Med Chem (2020 11 15) |
33007552
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2020 |
Production of a specific monoclonal antibody for 1-naphthol based on novel hapten strategy and devel ... | Chen, Zi-Jian; Liu, Xi-Xia; Xiao, Zhi-Li; Fu, Hui-Jun; Huang, Yu-Ping; Huang, Shu-Yi; Shen, Y ... | P42ES004699, R35ES030443 | Ecotoxicol Environ Saf (2020 Jun 15) |
32247241
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2020 |
Protostane-type triterpenoids as natural soluble epoxide hydrolase inhibitors: Inhibition potentials ... | Sun, Cheng-Peng; Zhang, Juan; Zhao, Wen-Yu; Yi, Jing; Yan, Jian-Kun; Wang, Ya-Li; Morisseau, ... | P42ES004699, R35ES030443 | Bioorg Chem (2020 03) |
32032849
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2020 |
PTUPB ameliorates high-fat diet-induced non-alcoholic fatty liver disease via inhibiting NLRP3 infla ... | Sun, Chen-Chen; Zhang, Chen-Yu; Duan, Jia-Xi; Guan, Xin-Xin; Yang, Hui-Hui; Jiang, Hui-Ling; H ... | P42ES004699, R35ES030443 | Biochem Biophys Res Commun (2020 03 19) |
31973813
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2020 |
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellula ... | Fishbein, Anna; Wang, Weicang; Yang, Haixia; Yang, Jun; Hallisey, Victoria M; Deng, Jianjun; V ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2020 09 01) |
32801214
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2020 |
Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine. | Shihadih, Diyala S; Harris, Todd R; Kodani, Sean D; Hwang, Sung-Hee; Lee, Kin Sing Stephen; Mav ... | P42ES004699, R35ES030443 | Front Vet Sci (2020) |
33005645
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2020 |
Sensitive Immunochromatographic Assay Using Highly Luminescent Quantum Dot Nanobeads as Tracer for t ... | Li, Pan; Yang, Cuifeng; Liu, Beibei; Wu, Qin; Wang, Yulong; Dong, Sa; Zhang, Hanxiaoya; Vasyl ... | P42ES004699, R35ES030443 | Front Chem (2020) |
32760698
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2020 |
Simultaneous Target-Mediated Drug Disposition Model for Two Small-Molecule Compounds Competing for T ... | Wu, Nan; Hammock, Bruce D; Lee, Kin Sing Stephen; An, Guohua | P42ES004699, R35ES030443 | J Pharmacol Exp Ther (2020 07) |
32238455
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2020 |
Soluble Epoxide Hydrolase Inhibition by t-TUCB Promotes Brown Adipogenesis and Reduces Serum Triglyc ... | Overby, Haley; Yang, Yang; Xu, Xinyun; Graham, Katherine; Hildreth, Kelsey; Choi, Sue; Wan, D ... | P42ES004699, R35ES030443 | Int J Mol Sci (2020 Sep 24) |
32987880
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2020 |
Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis mode ... | Trindade-da-Silva, Carlos A; Clemente-Napimoga, Juliana T; Abdalla, Henrique B; Rosa, Sergio Mar ... | P42ES004699, R35ES030443 | FASEB J (2020 07) |
32400048
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2020 |
Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfuncti ... | Wang, Yuxin; Yang, Jun; Wang, Weicang; Sanidad, Katherine Z; Cinelli, Maris A; Wan, Debin; Hwa ... | P42ES004699, R35ES030443 | Proc Natl Acad Sci U S A (2020 04 14) |
32220957
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2020 |
Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain. | Wagner, Karen M; Gomes, Aldrin; McReynolds, Cindy B; Hammock, Bruce D | P42ES004699, R35ES030443 | Neurotherapeutics (2020 07) |
32875445
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2020 |
Suppression of inflammation and fibrosis using soluble epoxide hydrolase inhibitors enhances cardiac ... | Sirish, Padmini; Thai, Phung N; Lee, Jeong Han; Yang, Jun; Zhang, Xiao-Dong; Ren, Lu; Li, Nin ... | P42ES004699, R35ES030443 | Stem Cells Transl Med (2020 12) |
32790136
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2020 |
Unexpected Differences between Two Closely Related Bacterial P450 Camphor Monooxygenases. | Murarka, Vidhi C; Batabyal, Dipanwita; Amaya, Jose A; Sevrioukova, Irina F; Poulos, Thomas L | R01ES025767 | Biochemistry (2020 07 28) |
32551522
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2020 |
Using sulfuramidimidoyl fluorides that undergo sulfur(VI) fluoride exchange for inverse drug discove ... | Brighty, Gabriel J; Botham, Rachel C; Li, Suhua; Nelson, Luke; Mortenson, David E; Li, Genchen ... | P42ES004699, R35ES030443 | Nat Chem (2020 10) |
32868886
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2020 |
Vascular Lipidomic Profiling of Potential Endogenous Fatty Acid PPAR Ligands Reveals the Coronary Ar ... | Edin, Matthew L; Lih, Fred B; Hammock, Bruce D; Thomson, Scott; Zeldin, Darryl C; Bishop-Bailey ... | P42ES004699, R35ES030443 | Cells (2020 04 29) |
32365470
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2020 |
Vitamin D deficiency serves as a precursor to stunted growth and central adiposity in zebrafish. | Knuth, Megan M; Mahapatra, Debabrata; Jima, Dereje; Wan, Debin; Hammock, Bruce D; Law, Mac; Ku ... | P30ES025128, P42ES004699, R35ES030443, T32ES007046 | Sci Rep (2020 09 29) |
32994480
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2020 |
ω-3 Polyunsaturated Fatty Acids on Colonic Inflammation and Colon Cancer: Roles of Lipid-Metabolizin ... | Tu, Maolin; Wang, Weicang; Zhang, Guodong; Hammock, Bruce D | P42ES004699, R35ES030443 | Nutrients (2020 Oct 28) |
33126566
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2020 |
1-Trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea, a Selective and Potent Dual Inhibitor o ... | Liang, Zhibin; Zhang, Bei; Xu, Meng; Morisseau, Christophe; Hwang, Sung Hee; Hammock, Bruce D; ... | P42ES004699, R35ES030443 | ACS Chem Neurosci (2019 09 18) |
31378059
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2019 |
Anti-inflammatory treatment with a soluble epoxide hydrolase inhibitor attenuates seizures and epile ... | Shen, Yijun; Peng, Weifeng; Chen, Qinglan; Hammock, Bruce D; Liu, Junyan; Li, Dongyang; Yang, ... | P42ES004699, R35ES030443 | Brain Behav Immun (2019 10) |
31306773
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2019 |
Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts f ... | Suter, Melissa A; Aagaard, Kjersti M; Coarfa, Cristian; Robertson, Matthew; Zhou, Guodong; Jack ... | P42ES027725, R01ES029382 | Biochem Biophys Res Commun (2019 08 20) |
31208719
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2019 |
Chemical Activation of the Constitutive Androstane Receptor Leads to Activation of Oxidant-Induced N ... | Rooney, John P; Oshida, Keiyu; Kumar, Ramiya; Baldwin, William S; Corton, J Christopher | R15ES017321, R15ES017321 | Toxicol Sci (2019 01 01) |
30203046
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2019 |
Conformational Response of N-Terminally Truncated Cytochrome P450 3A4 to Ligand Binding in Solution. | Chuo, Shih-Wei; Liou, Shu-Hao; Wang, Lee-Ping; Britt, R David; Poulos, Thomas L; Sevrioukova, ... | R01ES025767 | Biochemistry (2019 09 17) |
31456404
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2019 |
Cyp2b-null male mice are susceptible to diet-induced obesity and perturbations in lipid homeostasis. | Heintz, Melissa M; Kumar, Ramiya; Rutledge, Meredith M; Baldwin, William S | R15ES017321, R15ES017321 | J Nutr Biochem (2019 08) |
31202118
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2019 |
Drug-Target Residence Time Affects in Vivo Target Occupancy through Multiple Pathways. | Lee, Kin Sing Stephen; Yang, Jun; Niu, Jun; Ng, Connie J; Wagner, Karen M; Dong, Hua; Kodani, ... | R35ES030443 | ACS Cent Sci (2019 Sep 25) |
31572788
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2019 |
Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation. | Dileepan, Mythili; Rastle-Simpson, Stephanie; Greenberg, Yana; Wijesinghe, Dayanjan S; Kumar, N ... | R35ES030443 | Front Pharmacol (2019) |
31611798
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2019 |
Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic ac ... | Rand, Amy A; Rajamani, Anita; Kodani, Sean D; Harris, Todd R; Schlatt, Lukas; Barnych, Bodgan; ... | P42ES004699, R35ES030443 | J Lipid Res (2019 12) |
31641036
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2019 |
Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules. | Sevrioukova, Irina | R01ES025767 | Biochemistry (2019 02 19) |
30676743
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2019 |
Lung genotoxicity of benzo(a)pyrene in vivo involves reactivation of LINE-1 retrotransposon and earl ... | Hassanin, A A I; Tavera-Garcia, M; Moorthy, B; Zhou, G D; Ramos, K S | P42ES027725, R01ES029382 | Am J Physiol Lung Cell Mol Physiol (2019 12 01) |
31596105
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2019 |
Modulating Linker Composition of Haptens Resulted in Improved Immunoassay for Histamine. | Luo, Lin; Wei, Xiao-Qun; Jia, Bao-Zhu; Yang, Jin-Yi; Shen, Yu-Dong; Hammock, Bruce; Dong, Jie ... | P42ES004699, R35ES030443 | Biomolecules (2019 10 11) |
31614550
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2019 |
Phase 0 of the Xenobiotic Response: Nuclear Receptors and Other Transcription Factors as a First Ste ... | Baldwin, William S | R15ES017321, R15ES017321 | Nucl Receptor Res (2019) |
31815118
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2019 |
Pilot-Scale Pyrolytic Remediation of Crude-Oil-Contaminated Soil in a Continuously-Fed Reactor: Trea ... | Song, Wen; Vidonish, Julia E; Kamath, Roopa; Yu, Pingfeng; Chu, Chun; Moorthy, Bhagavatula; Ga ... | P42ES027725, R01ES029382 | Environ Sci Technol (2019 02 19) |
30681845
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2019 |
Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deox ... | Chen, Yu-Jie; Zhang, Jian; Zhu, Ping-Ping; Tan, Xian-Wen; Lin, Qiu-Hong; Wang, Wen-Xia; Yin, ... | R01ES025767 | Drug Metab Dispos (2019 06) |
30918015
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2019 |
Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, ... | Sevrioukova, Irina F | R01ES025767 | Int J Mol Sci (2019 Aug 30) |
31480231
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2019 |
Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group St ... | Samuels, Eric R; Sevrioukova, Irina | R01ES025767 | Biochemistry (2019 04 16) |
30912932
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2019 |
Transcriptomic profiling identifies novel mechanisms of transcriptional regulation of the cytochrome ... | Taneja, Guncha; Maity, Suman; Jiang, Weiwu; Moorthy, Bhagavatula; Coarfa, Cristian; Ghose, Rom ... | R01ES029382 | Sci Rep (2019 04 30) |
31040347
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2019 |
Cyp2b-Knockdown Mice Poorly Metabolize Corn Oil and Are Age-Dependent Obese. | Damiri, Basma; Baldwin, William S | R15ES017321, R15ES017321 | Lipids (2018 09) |
30421529
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2018 |
Direct Synthesis of α-Thio Aromatic Acids from Aromatic Amino Acids. | Samuels, Eric R; Sevrioukova, Irina | R01ES025767 | Tetrahedron Lett (2018 Mar 21) |
30140110
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2018 |
High fat diet induced obesity is mitigated in Cyp3a-null female mice. | Kumar, Ramiya; Litoff, Elizabeth J; Boswell, W Tyler; Baldwin, William S | R15ES017321, R15ES017321 | Chem Biol Interact (2018 Jun 01) |
29738703
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2018 |
Inhibition of Human CYP3A4 by Rationally Designed Ritonavir-Like Compounds: Impact and Interplay of ... | Samuels, Eric R; Sevrioukova, Irina | R01ES025767 | Mol Pharm (2018 01 02) |
29232137
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2018 |
Non-Mammalian Nuclear Receptors: From Evolution to Human Disease. | Gissendanner, Chris R; Baldwin, William S; Schaaf, Marcel J M | R15ES017321, R15ES017321 | Nucl Receptor Res (2018) |
30221173
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2018 |
Steroid bioconjugation to a CYP3A4 allosteric site and its effect on substrate binding and coupling ... | Polic, Vanja; Sevrioukova, Irina F; Auclair, Karine | R01ES025767 | Arch Biochem Biophys (2018 09 01) |
29958895
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2018 |
Annotation of the Nuclear Receptors in an Estuarine Fish species, Fundulus heteroclitus. | Baldwin, William S; Boswell, W Tyler; Ginjupalli, Gautam; Litoff, Elizabeth J | R15ES017321, R15ES017321 | Nucl Receptor Res (2017) |
28804711
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2017 |
Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-n ... | Kumar, Ramiya; Mota, Linda C; Litoff, Elizabeth J; Rooney, John P; Boswell, W Tyler; Courter, ... | R15ES017321, R15ES017321 | PLoS One (2017) |
28350814
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2017 |
Exchange of polar lipids from adults to neonates in Daphnia magna: Perturbations in sphingomyelin al ... | Sengupta, Namrata; Reardon, Delaney C; Gerard, Patrick D; Baldwin, William S | R15ES017321, R15ES017321 | PLoS One (2017) |
28542405
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2017 |
Heme Binding Biguanides Target Cytochrome P450-Dependent Cancer Cell Mitochondria. | Guo, Zhijun; Sevrioukova, Irina F; Denisov, Ilia G; Zhang, Xia; Chiu, Ting-Lan; Thomas, Dafydd ... | P30ES013508, R01ES025767 | Cell Chem Biol (2017 Oct 19) |
28919040
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2017 |
High-Level Production and Properties of the Cysteine-Depleted Cytochrome P450 3A4. | Sevrioukova, Irina F | R01ES025767 | Biochemistry (2017 06 20) |
28590129
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2017 |
RNA sequencing indicates that atrazine induces multiple detoxification genes in Daphnia magna and th ... | Schmidt, Allison M; Sengupta, Namrata; Saski, Christopher A; Noorai, Rooksana E; Baldwin, Willi ... | R15ES017321, R15ES017321 | Chemosphere (2017 Dec) |
28968576
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2017 |
Soluble Epoxide Hydrolase Inhibitor Suppresses the Expression of Triggering Receptor Expressed on My ... | Dong, Liang; Zhou, Yong; Zhu, Zhao-Qiong; Liu, Tian; Duan, Jia-Xi; Zhang, Jun; Li, Ping; Hamm ... | P42ES004699, R35ES030443 | Inflammation (2017 Feb) |
27696333
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2017 |
Structural basis for regiospecific midazolam oxidation by human cytochrome P450 3A4. | Sevrioukova, Irina F; Poulos, Thomas L | R01ES025767 | Proc Natl Acad Sci U S A (2017 01 17) |
28031486
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2017 |
Perturbations in polar lipids, starvation survival and reproduction following exposure to unsaturate ... | Sengupta, Namrata; Gerard, Patrick D; Baldwin, William S | R15ES017321, R15ES017321 | Chemosphere (2016 Feb) |
26606184
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2016 |
Arachidonic acid enhances reproduction in Daphnia magna and mitigates changes in sex ratios induced ... | Ginjupalli, Gautam K; Gerard, Patrick D; Baldwin, William S | R15ES017321, R15ES017321 | Environ Toxicol Chem (2015 Mar) |
25393616
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2015 |
Repression of multiple CYP2D genes in mouse primary hepatocytes with a single siRNA construct. | Elraghy, Omaima; Baldwin, William S | R15ES017321, R15ES017321 | In Vitro Cell Dev Biol Anim (2015 Jan) |
25124873
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2015 |
The HR96 activator, atrazine, reduces sensitivity of D. magna to triclosan and DHA. | Sengupta, Namrata; Litoff, Elizabeth J; Baldwin, William S | R15ES017321, R15ES017321 | Chemosphere (2015 Jun) |
25747156
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2015 |
Annotation of the Daphnia magna nuclear receptors: comparison to Daphnia pulex. | Litoff, Elizabeth J; Garriott, Travis E; Ginjupalli, Gautam K; Butler, LaToya; Gay, Claudy; Sco ... | R15ES017321, R15ES017321 | Gene (2014 Nov 15) |
25239664
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2014 |
The HR97 (NR1L) group of nuclear receptors: a new group of nuclear receptors discovered in Daphnia s ... | Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S | R15ES017321, R15ES017321 | Gen Comp Endocrinol (2014 Sep 15) |
25092536
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2014 |
The time- and age-dependent effects of the juvenile hormone analog pesticide, pyriproxyfen on Daphni ... | Ginjupalli, Gautam K; Baldwin, William S | R15ES017321, R15ES017321 | Chemosphere (2013 Aug) |
23714148
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2013 |
Daphnia HR96 is a promiscuous xenobiotic and endobiotic nuclear receptor. | Karimullina, Elina; Li, Yangchun; Ginjupalli, Gautam K; Baldwin, William S | R15ES017321, R15ES017321 | Aquat Toxicol (2012 Jul 15) |
22466357
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2012 |
Lentiviral-mediated RNAi knockdown yields a novel mouse model for studying Cyp2b function. | Damiri, Basma; Holle, Eric; Yu, Xianzhong; Baldwin, William S | R15ES017321, R15ES017321 | Toxicol Sci (2012 Feb) |
22083726
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2012 |
Nonylphenol-mediated CYP induction is PXR-dependent: The use of humanized mice and human hepatocytes ... | Mota, Linda C; Barfield, Christina; Hernandez, Juan P; Baldwin, William S | R15ES017321, R15ES017321 | Toxicol Appl Pharmacol (2011 May 1) |
21376070
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2011 |
Selective imaging and killing of cancer cells with protein-activated near-infrared fluorescing nanop ... | Rungta, Parul; Bandera, Yuriy P; Roeder, Ryan D; Li, Yangchun; Baldwin, William S; Sharma, Dee ... | R15ES017321, R15ES017321 | Macromol Biosci (2011 Jul 07) |
21480531
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2011 |
Constitutive androstane receptor -null mice are sensitive to the toxic effects of parathion: associa ... | Mota, Linda C; Hernandez, Juan P; Baldwin, William S | R15ES017321, R15ES017321 | Drug Metab Dispos (2010 Sep) |
20573718
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2010 |
Dose-responsive gene expression changes in juvenile and adult mummichogs (Fundulus heteroclitus) aft ... | Gonzalez, Horacio O; Hu, Jianjun; Gaworecki, Kristen M; Roling, Jonathan A; Baldwin, William S; ... | R15ES017321, R15ES017321 | Mar Environ Res (2010 Aug) |
20451245
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2010 |
Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: ... | Van Aggelen, Graham; Ankley, Gerald T; Baldwin, William S; Bearden, Daniel W; Benson, William H ... | R15ES017321, R15ES017321 | Environ Health Perspect (2010 Jan) |
20056575
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2010 |
Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription ... | Hannas, Bethany R; Wang, Ying H; Baldwin, William S; Li, Yangchun; Wallace, Andrew D; LeBlanc, ... | R15ES017321, R15ES017321, T32ES007046 | Gen Comp Endocrinol (2010 Jun 1) |
20346363
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2010 |
A concentration addition model for the activation of the constitutive androstane receptor by xenobio ... | Baldwin, William S; Roling, Jonathan A | R15ES017321, R15ES017321 | Toxicol Sci (2009 Jan) |
18832183
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2009 |
Activation of CAR and PXR by Dietary, Environmental and Occupational Chemicals Alters Drug Metabolis ... | Hernandez, J P; Mota, L C; Baldwin, W S | R15ES017321, R15ES017321 | Curr Pharmacogenomics Person Med (2009 Jun 01) |
20871735
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2009 |
Sexually dimorphic regulation and induction of P450s by the constitutive androstane receptor (CAR). | Hernandez, J P; Mota, L C; Huang, W; Moore, D D; Baldwin, W S | R15ES017321, R15ES017321 | Toxicology (2009 Feb 4) |
19041682
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2009 |