Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Internet Explorer is no longer a supported browser.

This website may not display properly with Internet Explorer. For the best experience, please use a more recent browser such as the latest versions of Google Chrome, Microsoft Edge, and/or Mozilla Firefox. Thank you.

COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC. Get the latest research information from NIH.

Your Environment. Your Health.

Harvard School of Public Health

Superfund Research Program

Lead Exposure and Accumulation in Bone in Adolescents

Project Leader: P. Barry Ryan (Emory University School of Public Health)
Grant Number: P42ES005947
Funding Period: 1995 - 2000

Learn More About the Grantee

Visit the grantee's eNewsletter page Visit the grantee's Twitter page

Project Summary (1995-2000)

The major focus of this project is the repeated simultaneous measurement of environmental lead concentrations, blood lead concentrations, and bone lead concentrations in adolescents. The target group consists of high school students who are unlikely to have received significant occupational exposure to lead. The study started with a baseline evaluation of the cohort, including questionnaire administration, environmental sampling in and around their homes, a blood lead measurement, and a bone lead measurement. This procedure is repeated at one year intervals. Also, researchers are examining the ability of the bone lead technique to identify those adolescents who, in early childhood, were diagnosed as lead poisoned. Through this study and the following of adolescents for a period of several years, scientists hope to gain new insights regarding the kinetics of lead uptake by bone during this important growth period. Finally, researchers are examining the relationship between the ALA-D gene polymorphism on measured blood lead and bone lead concentrations.

 

 

Back
to Top