Skip Navigation
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Your Environment. Your Health.

Columbia University

Superfund Research Program

Health Effects and Geochemistry of Arsenic and Lead

Center Director: Joseph H. Graziano
Grant Number: P42ES010349
Funding Period: 2000-2021

Learn More About the Grantee

Visit the grantee's eNewsletter page Visit the grantee's Twitter page Visit the grantee's Video page

Summary (2000-2006)

The Columbia University Superfund Basic Research Program, that began in 2000, is focused on the health issues arising from exposure to metals, specifically arsenic and lead contamination of soils and drinking water and the geochemistry of these two elements. The program consists of seven research projects (4 biomedical, 3 non-biomedical), three support cores (trace metals, geochemistry and hydrology), and administrative and training cores. Two biomedical projects are focusing on understanding arsenic toxicity. They include describing the adsorption of lead and its bioavailability, and elucidating the mutagenic pathways involved in arsenic-induced carcinogenesis. The two other biomedical projects are epidemiology studies in Bangladesh. One study is exploring critical dose relationships between drinking water, arsenic, and health outcomes. In the other epidemiology study investigators are examining arsenic metabolism in the neonatal period. The three non-biomedical projects are examining arsenic mobilization in Bangladesh, mobilization and redistribution of arsenic at Superfund sites in the U.S., and remediation strategies for arsenic enrichment in groundwater.

Back
to Top