Superfund Research Program


September 2017

New research shows that deletions or duplications of long stretches of DNA, also known as copy number variations (CNVs), that occur in several gene locations are associated with a higher risk of developing arsenic-induced skin lesions. Skin lesions are a hallmark of arsenic toxicity that appear relatively early with chronic arsenic exposure. This newly discovered link may help to explain why some people exposed to arsenic develop skin lesions and get sick while others exposed to the same levels do not.