Superfund Research Program

Development and Application of Integrated In Vitro and Cell-Based Bioassays

Project Leader: Michael S. Denison
Co-Investigator: Isaac N. Pessah
Grant Number: P42ES004699
Funding Period: 1995-2015

Project-Specific Links

Grant Recipient Patent List

Patents

• Acyl Piperidine Inhibitors of Soluble Epoxide Hydrolase

  Number: US 2010-299495P
  Year: 2012
  Patent Status: Issued
  Authors: Hammock, B.D., C. Morisseau, K. Lee, T.E. Rose

• Bioassay for Detecting 2,3,7,8-tetrachlorodibenzo-para-dioxin and TCDD-like Compounds and Novel Recombinant Cell Line Useful Therefore

  Number: 5,854,010
  Year: 1998
  Patent Status: Issued
  Authors: Denison, M.S., A. Brouwer, G.C. Clark

• Inhibitor of Apoptosis Proteins and Nucleic Acids and Methods for Making and Using Them

  Number: 8,119,404
  Year: 2012
  Patent Status: Issued
  Authors: Huang, Q., J. Reed, B.D. Hammock, Q.L. Deveraux, S. Maeda

• Modeling Combinatorial Interventions for Protecting Against Threat Agents

  Number: 2012-035-0
  Year: 2012
  Patent Status: Issued
  Authors: Pessah, I.N.

• Modulation of Bioactive Epoxy-Fatty Acid Levels by Phosphodiesterase Inhibitors

  Number: PCT/US2011/036511
  Year: 2011
  Patent Status: Pending
  Authors: Hammock, B.D., A.B. Inceoglu, K.M. Wagner, N. Schebb

• Preparation of Novel 1,3-Substituted Ureas as Inhibitors of Soluble Epoxide Hydrolase

  Number: 2007-549-2
  Year: 2009
  Patent Status: Pending
  Authors: Sanborn, J.R., B.D. Hammock, S.H. Hwang, P.D. Jones, C. Morisseau

• Sorafenib Derivatives as P21 Inhibitors

  Number: 10,449,1882
  Year: 2019
  Patent Status: Issued
  Authors: Weiss, R.H., B.D. Hammock, H. Inoue, S.H. Hwang

• Sorafenib Derivatives as sEH Inhibitors

  Number: PCT/US2012/025074
  Year: 2012
  Patent Status: Pending
  Authors: Weiss, R.H., B.D. Hammock, H. Inoue, S.H. Hwang

• Treatment of Inflammatory Disorders in Non-Human Mammals

  Number: 10,383,835
  Year: 2019
  Patent Status: Issued
  Authors: Guedes, A.P., B.D. Hammock, C. Morisseau