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| Publication Title | Authors | Grant Number(s) | Journal (Pub date) | PubMed Link | Pub Year |
|---|---|---|---|---|---|
| A persistent variant telomere sequence in a human pedigree. | Hinchie, Angela M; Sanford, Samantha L; Loughridge, Kelly E; Sutton, Rachel M; Parikh, Anishka ... | R35ES030396 | Nat Commun (2024 Jun 01) |
38824190
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2024 |
| Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Perturb mRNA Splicing through Aberrant Inte ... | Chen, Xingyuan; Cao, Zhongwen; Wang, Yinsheng | R35ES031707 | Anal Chem (2024 Jun 11) |
38795036
|
2024 |
| Analysis of cytosine deamination events in excision repair sequencing reads reveals mechanisms of in ... | Morledge-Hampton, Benjamin; Kalyanaraman, Ananth; Wyrick, John J | R01ES028698, R01ES032814 | Nucleic Acids Res (2024 Feb 28) |
38109317
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2024 |
| Analysis of NIH K99/R00 awards and the career progression of awardees. | Woitowich, Nicole C; Hengel, Sarah R; Solis, Christopher; Vilgalys, Tauras P; Babdor, Joel; Tyr ... | R00ES033738 | Elife (2024 Jan 19) |
38240745
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2024 |
| Aurkin-A, a TPX2-Aurora A small molecule inhibitor disrupts Alisertib-induced polyploidy in aggressi ... | Conway, Patrick J; De La Peña Avalos, Bárbara; Dao, Jonathan; Montagnino, Sebastian; Kovalskyy, ... | R21ES035997 | Neoplasia (2024 Sep) |
38875929
|
2024 |
| BG4 antibody can recognize telomeric G-quadruplexes harboring destabilizing base modifications and l ... | Johnson, Samuel A; Paul, Tapas; Sanford, Samantha L; Schnable, Brittani L; Detwiler, Ariana C; ... | R35ES030396, R35ES031638 | Nucleic Acids Res (2024 Feb 28) |
38153143
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2024 |
| BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response. | Jiang, Haoyang; Zhang, Tianpeng; Kaur, Hardeep; Shi, Tao; Krishnan, Aravind; Kwon, Youngho; Su ... | R01ES007061 | Mol Cell (2024 May 02) |
38593805
|
2024 |
| CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stres ... | Acharya, Ganesh; Mani, Chinnadurai; Sah, Naresh; Saamarthy, Karunakar; Young, Robert; Reedy, M ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Cell Death Discov (2024 Jun 11) |
38862485
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2024 |
| Control of DNA replication in vitro using a reversible replication barrier. | Vontalge, Emma J; Kavlashvili, Tamar; Dahmen, Steven N; Cranford, Matthew T; Dewar, James M | R01ES034847, T32ES007028 | Nat Protoc (2024 Jul) |
38594502
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2024 |
| Controlling genome topology with sequences that trigger post-replication gap formation during replis ... | Pham, Phuong; Wood, Elizabeth A; Dunbar, Emma L; Cox, Michael M; Goodman, Myron F | R35ES028343 | Nucleic Acids Res (2024 Jun 24) |
38676944
|
2024 |
| Controlling Genome Topology with Sequences that Trigger Post-replication Gap Formation During Replis ... | Pham, Phuong; Wood, Elizabeth A; Dunbar, Emma L; Cox, Michael M; Goodman, Myron F | R35ES028343 | bioRxiv (2024 Apr 10) |
37873128
|
2024 |
| CRISPR knockout genome-wide screens identify the HELQ-RAD52 axis in regulating the repair of cisplat ... | Pale, Lindsey M; Khatib, Jude B; Nicolae, Claudia M; Moldovan, George-Lucian | R01ES026184 | bioRxiv (2024 Apr 20) |
38659927
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2024 |
| Cross-species investigation into the requirement of XPA for nucleotide excision repair. | Kose, Cansu; Cao, Xuemei; Dewey, Evan B; Malkoç, Mustafa; Adebali, Ogün; Sekelsky, Jeff; Linds ... | R01ES033414 | Nucleic Acids Res (2024 Jan 25) |
37994737
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2024 |
| Deciphering the crystal structure of a novel nanobody against the NEIL1 DNA glycosylase. | Thompson, Marlo K; Sharma, Nidhi; Thorn, Andrea; Prakash, Aishwarya | R01ES030084 | Acta Crystallogr D Struct Biol (2024 Feb 01) |
38289715
|
2024 |
| Defining high confidence targets of differential CpG methylation in response to in utero arsenic exp ... | Lumour-Mensah, Tabitha; Lemos, Bernardo | R01ES027981, T32ES007069 | Toxicol Appl Pharmacol (2024 Jan) |
38030093
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2024 |
| Deregulated DNA ADP-ribosylation impairs telomere replication. | Wondisford, Anne R; Lee, Junyeop; Lu, Robert; Schuller, Marion; Groslambert, Josephine; Bhargav ... | R35ES030396 | Nat Struct Mol Biol (2024 May) |
38714889
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2024 |
| Distinct regulation of ATM signaling by DNA single-strand breaks and APE1. | Zhao, Haichao; Li, Jia; You, Zhongsheng; Lindsay, Howard D; Yan, Shan | R21ES032966 | Nat Commun (2024 Aug 07) |
39112456
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2024 |
| DNA polymerase ε and δ variants drive mutagenesis in polypurine tracts in human tumors. | Ostroverkhova, Daria; Tyryshkin, Kathrin; Beach, Annette K; Moore, Elizabeth A; Masoudi-Sobhanza ... | R01ES015869 | Cell Rep (2024 Jan 23) |
38219146
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2024 |
| DNA polymerase κ participates in early S-phase DNA replication in human cells. | Tang, Feng; Wang, Yinan; Zhao, Ting; Yuan, Jun; Kellum Jr, Andrew H; Wang, Yinsheng | K99ES035446, R35ES031707, T32ES018827 | Proc Natl Acad Sci U S A (2024 Jul 09) |
38950361
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2024 |
| DNA Repair in Nucleosomes: Insights from Histone Modifications and Mutants. | Selvam, Kathiresan; Wyrick, John J; Parra, Michael A | R01ES028698, R01ES032814, R21ES035139 | Int J Mol Sci (2024 Apr 16) |
38673978
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2024 |
| Effective density of inhaled environmental and engineered nanoparticles and its impact on the lung d ... | Lizonova, Denisa; Nagarkar, Amogh; Demokritou, Philip; Kelesidis, Georgios A | P30ES005022, R01ES023350 | Part Fibre Toxicol (2024 Feb 17) |
38368385
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2024 |
| Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. | Sarsam, Reta D; Xu, Jun; Lahiri, Indrajit; Gong, Wenzhi; Li, Qingrong; Oh, Juntaek; Zhou, Zhe ... | R03ES033789, R03ES033789 | Proc Natl Acad Sci U S A (2024 Jan 16) |
38194460
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2024 |
| Elf1 promotes transcription-coupled repair in yeast by using its C-terminal domain to bind TFIIH. | Selvam, Kathiresan; Xu, Jun; Wilson, Hannah E; Oh, Juntaek; Li, Qingrong; Wang, Dong; Wyrick, ... | R01ES028698, R01ES032814, R21ES035139 | Nat Commun (2024 Jul 23) |
39043658
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2024 |
| Enabling novel paradigms: a biological questions-based approach to human chemical hazard and drug sa ... | Berridge, Brian R; Bucher, John R; Sistare, Frank; Stevens, James L; Chappell, Grace A; Clemons ... | R01ES021007 | Toxicol Sci (2024 Feb 28) |
38134427
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2024 |
| Enzymatic Processing of DNA-Protein Crosslinks. | Essawy, Maram M; Campbell, Colin | R01ES023350 | Genes (Basel) (2024 Jan 10) |
38254974
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2024 |
| Evolved histone tail regulates 53BP1 recruitment at damaged chromatin. | Kelliher, Jessica L; Folkerts, Melissa L; Shen, Kaiyuan V; Song, Wan; Tengler, Kyle; Stiefel, ... | R21ES035997 | Nat Commun (2024 May 31) |
38821984
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2024 |
| Exposure to Pesticides and Breast Cancer in an Agricultural Region in Brazil. | Panis, Carolina; Candiotto, Luciano Zanetti Pessoa; Gaboardi, Shaiane Carla; Teixeira, Géssica T ... | R01ES027981 | Environ Sci Technol (2024 Jun 18) |
38844831
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2024 |
| Formation and Properties of DNA Adducts Generated by Reactions of Abasic Sites with 1,2-Aminothiols ... | Gomina, Anuoluwapo; Islam, Tanhaul; Shim, Garam; Lei, Zhentian; Gates, Kent S | R01ES021007 | Chem Res Toxicol (2024 Feb 19) |
38181204
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2024 |
| Forming a chromium-based interstrand DNA crosslink: Implications for carcinogenicity. | Brown, Silas; Marchi, Sydney; Thomas, C Sumner; Hale, Ashlyn R; Lockart, Molly; Bowman, Michae ... | R15ES033800 | J Inorg Biochem (2024 Feb) |
38039560
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2024 |
| Functional characterization of single nucleotide polymorphic variants of DNA repair enzyme NEIL1 in ... | Zuckerman, Jamie T; Jackson, Asia Sage; Minko, Irina G; Kant, Melis; Jaruga, Pawel; Stone, Mic ... | R01ES031086 | DNA Repair (Amst) (2024 Jul) |
38795603
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2024 |
| Functional roles and cancer variants of the bifunctional glycosylase NEIL2. | Hua, Anh B; Sweasy, Joann B | R35ES031708 | Environ Mol Mutagen (2024 Apr) |
37310399
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2024 |
| Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-st ... | Raices, Marilina; Balmir, Fabiola; Silva, Nicola; Li, Wei; Grundy, McKenzie K; Hoffman, Dane K ... | R01ES030335 | bioRxiv (2024 May 30) |
38463951
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2024 |
| Genome scale CRISPR screens identify actin capping proteins as key modulators of therapeutic respons ... | Verma, Nipun; Renauer, Paul A; Dong, Chuanpeng; Xin, Shan; Lin, Qianqian; Zhang, Feifei; Glaze ... | R01ES005775 | bioRxiv (2024 Jan 15) |
38293095
|
2024 |
| Genome-wide analysis of transcription-coupled repair reveals novel transcription events in Caenorhab ... | Kose, Cansu; Lindsey-Boltz, Laura A; Sancar, Aziz; Jiang, Yuchao | R01ES033414 | PLoS Genet (2024 Jul) |
39028758
|
2024 |
| Genome-wide analysis of transcription-coupled repair reveals novel transcription events in Caenorhab ... | Kose, Cansu; Lindsey-Boltz, Laura A; Sancar, Aziz; Jiang, Yuchao | R01ES033414 | bioRxiv (2024 Mar 29) |
37904932
|
2024 |
| Genome-wide impact of cytosine methylation and DNA sequence context on UV-induced CPD formation. | Wilson, Hannah E; Wyrick, John J | R01ES028698, R01ES032814, R21ES035139 | Environ Mol Mutagen (2024 Apr) |
37554110
|
2024 |
| Global repair is the primary nucleotide excision repair subpathway for the removal of pyrimidine-pyr ... | Kaya, Sezgi; Erdogan, Dugcar Ebrar; Sancar, Aziz; Adebali, Ogun; Oztas, Onur | R01ES033414 | Sci Rep (2024 Feb 08) |
38332020
|
2024 |
| Harnessing the effects of hypoxia-like inhibition on homology-directed DNA repair. | Altwerger, Gary; Ghazarian, Maddie; Glazer, Peter M | R01ES005775 | Semin Cancer Biol (2024 Jan) |
38029867
|
2024 |
| Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in th ... | Almohdar, Danah; Gulkis, Mitchell; Ortiz, Abigail; Tang, Qun; Sobol, Robert W; Çağlayan, Melik ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | J Mol Biol (2024 Feb 15) |
38135179
|
2024 |
| Inspiring basic and applied research in genome integrity mechanisms: Dedication to Samuel H. Wilson. | Yan, Shan; Gaddameedhi, Shobhan; Sobol, Robert W | P01ES028949, P30ES025128, R01ES030113, R21ES032966, R44ES032522, U01ES029518, U01ES029518 | Environ Mol Mutagen (2024 Apr) |
38619433
|
2024 |
| Interplay of the Tfb1 pleckstrin homology domain with Rad2 and Rad4 in transcription coupled and glo ... | Gong, Wenzhi; Holmberg, Hannah; Lu, Cheng; Huang, Michelle; Li, Shisheng | R03ES033789, R03ES033789 | Nucleic Acids Res (2024 Jun 24) |
38634797
|
2024 |
| Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies. | Li, Yafang; Xiao, Xiangjun; Li, Jianrong; Han, Younghun; Cheng, Chao; Fernandes, Gail F; Slewi ... | R00ES033259 | Cancer Epidemiol Biomarkers Prev (2024 Mar 01) |
38180474
|
2024 |
| Mass Spectral Library for DNA Adductomics. | Walmsley, Scott J; Guo, Jingshu; Tarifa, Anamary; DeCaprio, Anthony P; Cooke, Marcus S; Turesky ... | R01ES030557, R01ES030765 | Chem Res Toxicol (2024 Feb 19) |
38231175
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2024 |
| Mass Spectrometry-Based Method to Measure Aflatoxin B1 DNA Adducts in Formalin-Fixed Paraffin-Embedd ... | Bellamri, Medjda; Yao, Lihua; Tomar, Rachana; Vartanian, Vladimir; Rizzo, Carmelo J; Stone, Mi ... | R01ES031086, U2CES026533 | Chem Res Toxicol (2024 Apr 15) |
38498000
|
2024 |
| Mouse models to explore the biological and organismic role of DNA polymerase beta. | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Environ Mol Mutagen (2024 Apr) |
38619421
|
2024 |
| Mutations of the circadian clock genes Cry, Per, or Bmal1 have different effects on the transcribed ... | Yang, Yanyan; Wu, Gang; Sancar, Aziz; Hogenesch, John B | R01ES033414 | Proc Natl Acad Sci U S A (2024 Feb 20) |
38359290
|
2024 |
| Obesity Induces DNA Damage in Mammary Epithelial Cells Exacerbated by Acrylamide Treatment through C ... | Walton, Brenna; Kaplan, Noah; Hrdlicka, Brooke; Mehta, Kavi; Arendt, Lisa M | R00ES034058 | Toxics (2024 Jul 02) |
39058136
|
2024 |
| Oncometabolite 2-hydroxyglutarate suppresses basal protein levels of DNA polymerase beta that enhanc ... | Saville, Kate M; Al-Rahahleh, Rasha Q; Siddiqui, Aisha H; Andrews, Morgan E; Roos, Wynand P; Ko ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | DNA Repair (Amst) (2024 Aug) |
38897003
|
2024 |
| Oxidative DNA damage on the VEGF G-quadruplex forming promoter is repaired via long-patch BER. | Hussen, Adil S; Kravitz, Haley L; Freudenthal, Bret D; Whitaker, Amy M | R00ES031148 | Environ Mol Mutagen (2024 Apr) |
37606505
|
2024 |
| Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-dir ... | Thosar, Sanjana A; Barnes, Ryan P; Detwiler, Ariana; Bhargava, Ragini; Wondisford, Anne; O'Sull ... | R35ES030396 | Cell Rep (2024 Jan 23) |
38194346
|
2024 |
| PARP10 promotes the repair of nascent strand DNA gaps through RAD18 mediated translesion synthesis. | Khatib, Jude B; Dhoonmoon, Ashna; Moldovan, George-Lucian; Nicolae, Claudia M | R01ES026184 | Nat Commun (2024 Jul 23) |
39043663
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2024 |
| Poly-ADP-ribosylation dynamics, signaling, and analysis. | Al-Rahahleh, Rasha Q; Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Environ Mol Mutagen (2024 Sep 02) |
39221603
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2024 |
| Polyploidy in Cancer: Causal Mechanisms, Cancer-Specific Consequences, and Emerging Treatments. | Conway, Patrick J; Dao, Jonathan; Kovalskyy, Dmytro; Mahadevan, Daruka; Dray, Eloise | R21ES035997 | Mol Cancer Ther (2024 May 02) |
38315992
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2024 |
| Role of Translesion DNA Synthesis in the Metabolism of Replication-associated Nascent Strand Gaps. | Khatib, Jude B; Nicolae, Claudia M; Moldovan, George-Lucian | R01ES026184 | J Mol Biol (2024 Jan 01) |
37714300
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2024 |
| Screening DNA Damage in the Rat Kidney and Liver by Untargeted DNA Adductomics. | Ragi, Nagarjunachary; Walmsley, Scott J; Jacobs, Foster C; Rosenquist, Thomas A; Sidorenko, Vik ... | R01ES030765, U2CES026533 | Chem Res Toxicol (2024 Feb 19) |
38194517
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2024 |
| Single-molecule analysis of purified proteins and nuclear extracts: Insights from 8-oxoguanine glyco ... | Schaich, Matthew A; Weaver, Tyler M; Roginskaya, Vera; Freudenthal, Bret D; Van Houten, Bennett | F32ES034982, R35ES031638 | DNA Repair (Amst) (2024 Feb) |
38237481
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2024 |
| Single-stranded DNA binding protein hitches a ride with the Escherichia coli YoaA-χ helicase. | Weeks-Pollenz, Savannah J; Petrides, Matthew J; Davis, Robert; Harris, Kathryn K; Bloom, Linda ... | F31ES034652 | bioRxiv (2024 Jun 21) |
38948847
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2024 |
| Structural basis for the H2AK119ub1-specific DNMT3A-nucleosome interaction. | Chen, Xinyi; Guo, Yiran; Zhao, Ting; Lu, Jiuwei; Fang, Jian; Wang, Yinsheng; Wang, Gang Greg; ... | R35ES031707 | Nat Commun (2024 Jul 23) |
39043678
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2024 |
| Structure-guided functional suppression of AML-associated DNMT3A hotspot mutations. | Lu, Jiuwei; Guo, Yiran; Yin, Jiekai; Chen, Jianbin; Wang, Yinsheng; Wang, Gang Greg; Song, Ji ... | R35ES031707 | Nat Commun (2024 Apr 10) |
38600075
|
2024 |
| The aflatoxin B1-induced imidazole ring-opened guanine adduct: High mutagenic potential that is mini ... | Minko, Irina G; Kellum Jr, Andrew H; Stone, Michael P; Lloyd, R Stephen | R01ES031086 | Environ Mol Mutagen (2024 Apr) |
37303259
|
2024 |
| The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. | Hengel, Sarah R; Oppenheimer, Katherine G; Smith, Chelsea M; Schaich, Matthew A; Rein, Hayley L ... | R00ES033738, R01ES030335, R01ES031796, R35ES031638 | Nat Commun (2024 Aug 21) |
39169038
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2024 |
| The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. | Hengel, Sarah R; Oppenheimer, Katherine; Smith, Chelsea; Schaich, Matthew A; Rein, Hayley L; Ma ... | R00ES033738 | bioRxiv (2024 Feb 15) |
38405734
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2024 |
| The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA. | Hengel, Sarah R; Oppenheimer, Katherine G; Smith, Chelsea M; Schaich, Matthew A; Rein, Hayley L ... | R00ES033738, R01ES030335, R01ES031796, R35ES031638 | Nat Commun (2024 Aug 21) |
39169038
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2024 |
| Thymine DNA glycosylase combines sliding, hopping, and nucleosome interactions to efficiently search ... | Schnable, Brittani L; Schaich, Matthew A; Roginskaya, Vera; Leary, Liam P; Weaver, Tyler M; Fre ... | R35ES031638 | bioRxiv (2024 Jul 27) |
37873231
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2024 |
| Transcriptomic changes and gene fusions during the progression from Barrett's esophagus to esophagea ... | Fu, Yusi; Agrawal, Swati; Snyder, Daniel R; Yin, Shiwei; Zhong, Na; Grunkemeyer, James A; Diet ... | R00ES033259 | Biomark Res (2024 Aug 07) |
39113153
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2024 |
| Ubiquitin-mediated regulation of APE2 protein abundance. | McMahon, Anne; Zhao, Jianjun; Yan, Shan | R21ES032966 | J Biol Chem (2024 Jun) |
38705397
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2024 |
| USP1-dependent nucleolytic expansion of PRIMPOL-generated nascent DNA strand discontinuities during ... | Nusawardhana, Alexandra; Pale, Lindsey M; Nicolae, Claudia M; Moldovan, George-Lucian | R01ES026184 | Nucleic Acids Res (2024 Mar 21) |
38180818
|
2024 |
| UV damage induces production of mitochondrial DNA fragments with specific length profiles. | Waneka, Gus; Stewart, Joseph; Anderson, John R; Li, Wentao; Wilusz, Jeffrey; Argueso, Juan Luc ... | R00ES030015 | Genetics (2024 Jul 08) |
38722894
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2024 |
| Variable Inhibition of DNA Unwinding Rates Catalyzed by the SARS-CoV-2 Helicase Nsp13 by Structurall ... | Sales, Ana H; Fu, Iwen; Durandin, Alexander; Ciervo, Sam; Lupoli, Tania J; Shafirovich, Vladim ... | R01ES025987 | Int J Mol Sci (2024 Jul 19) |
39063172
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2024 |
| Variants in the first methionine of RAD51C are homologous recombination proficient due to an alterna ... | Rein, Hayley L; Bernstein, Kara A | R01ES030335, R01ES031796 | DNA Repair (Amst) (2024 Mar) |
38330859
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2024 |
| What Are the Implications of Cr(III) Serving as an Inhibitor of the Beta Subunit of Mitochondrial AT ... | Vincent, John B | R15ES033800 | Biol Trace Elem Res (2024 Apr) |
37580526
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2024 |
| Zinc finger proteins: guardians of genome stability. | Kamaliyan, Zeeba; Clarke, Thomas L | R00ES034443 | Front Cell Dev Biol (2024) |
39119040
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2024 |
| A half century of exploring DNA excision repair in chromatin. | Smerdon, Michael J; Wyrick, John J; Delaney, Sarah | R01ES028698, R01ES032814, R21ES035139 | J Biol Chem (2023 Sep) |
37527775
|
2023 |
| A multi-scale map of protein assemblies in the DNA damage response. | Kratz, Anton; Kim, Minkyu; Kelly, Marcus R; Zheng, Fan; Koczor, Christopher A; Li, Jianfeng; O ... | U01ES029518, U01ES029518 | Cell Syst (2023 Jun 21) |
37220749
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2023 |
| A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonucle ... | Das, Debanu; Duncton, Matthew A J; Georgiadis, Taxiarchis M; Pellicena, Patricia; Clark, Jennif ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Int J Mol Sci (2023 Nov 23) |
38068959
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2023 |
| A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair ... | Bralić, Amer; Tehseen, Muhammad; Sobhy, Mohamed A; Tsai, Chi-Lin; Alhudhali, Lubna; Yi, Gang; ... | R01ES032786 | Nucleic Acids Res (2023 Feb 22) |
36477609
|
2023 |
| Accumulation of 8-oxodG within the human mitochondrial genome positively associates with transcripti ... | Scala, Giovanni; Ambrosio, Susanna; Menna, Margherita; Gorini, Francesca; Caiazza, Carmen; Cook ... | R01ES030557 | NAR Genom Bioinform (2023 Dec) |
37954575
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2023 |
| Altered Nucleotide Insertion Mechanisms of Disease-Associated TERT Variants. | Welfer, Griffin A; Borin, Veniamin A; Cortez, Luis M; Opresko, Patricia L; Agarwal, Pratul K; F ... | R35ES030396 | Genes (Basel) (2023 Jan 21) |
36833208
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2023 |
| Analysis of NIH K99/R00 Awards and the Career Progression of Awardees. | Woitowich, Nicole C; Hengel, Sarah R; Solis, Christopher; Vilgalys, Tauras P; Babdor, Joel; Tyr ... | R00ES033738 | bioRxiv (2023 Dec 29) |
37162873
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2023 |
| APE1 recruits ATRIP to ssDNA in an RPA-dependent and -independent manner to promote the ATR DNA dama ... | Lin, Yunfeng; Li, Jia; Zhao, Haichao; McMahon, Anne; McGhee, Kelly; Yan, Shan | R21ES032966 | Elife (2023 May 22) |
37216274
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2023 |
| APE2: catalytic function and synthetic lethality draw attention as a cancer therapy target. | McMahon, Anne; Zhao, Jianjun; Yan, Shan | R21ES032966 | NAR Cancer (2023 Mar) |
36755963
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2023 |
| Assembly path dependence of telomeric DNA compaction by TRF1, TIN2, and SA1. | Liu, Ming; Pan, Hai; Kaur, Parminder; Wang, Lucia J; Jin, Miao; Detwiler, Ariana C; Opresko, ... | P30ES025128, R35ES030396 | Biophys J (2023 May 16) |
37081787
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2023 |
| ATR activation by Cr-DNA damage is a major survival response establishing late S and G2 checkpoints ... | Valiente, Sophia; Krawic, Casey; Zhitkovich, Anatoly | R01ES028072, R01ES031002, R01ES031979 | Toxicol Appl Pharmacol (2023 Oct 15) |
37734571
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2023 |
| Atypical genotoxicity of carcinogenic nickel(II): Linkage to dNTP biosynthesis, DNA-incorporated rNM ... | Krawic, Casey; Luczak, Michal W; Valiente, Sophia; Zhitkovich, Anatoly | R01ES028072, R01ES031002, R01ES031979 | J Biol Chem (2023 Dec) |
37890780
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2023 |
| AUTS2 Controls Neuronal Lineage Choice Through a Novel PRC1-Independent Complex and BMP Inhibition. | Geng, Zhuangzhuang; Wang, Qiang; Miao, Weili; Wolf, Trevor; Chavez, Jessenia; Giddings, Emily; ... | R35ES031707 | Stem Cell Rev Rep (2023 Feb) |
36258139
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2023 |
| Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosyla ... | Tomar, Rachana; Minko, Irina G; Sharma, Pankaj; Kellum, Andrew H; Lei, Li; Harp, Joel M; Ivers ... | R01ES031086 | Nucleic Acids Res (2023 May 08) |
37014002
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2023 |
| Binding of microRNA-122 to the hepatitis C virus 5' untranslated region modifies interactions with p ... | Scott, Seth; Li, You; Bermek, Oya; Griffith, Jack D; Lemon, Stanley M; Choi, Kyung H | R01ES031635 | Nucleic Acids Res (2023 Dec 11) |
37941151
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2023 |
| Break-induced replication orchestrates resection-dependent template switching. | Zhang, Tianpeng; Rawal, Yashpal; Jiang, Haoyang; Kwon, Youngho; Sung, Patrick; Greenberg, Roge ... | R01ES007061 | Nature (2023 Jul) |
37316655
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2023 |
| Characterization of the Escherichia coli XPD/Rad3 iron-sulfur helicase YoaA in complex with the DNA ... | Weeks-Pollenz, Savannah J; Ali, Yasmin; Morris, Leslie A; Sutera, Vincent A; Dudenhausen, Eliza ... | F31ES034652 | J Biol Chem (2023 Jan) |
36509145
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2023 |
| Chemical mechanisms of DNA damage by carcinogenic chromium(VI). | Krawic, Casey; Zhitkovich, Anatoly | R01ES028072, R01ES031002, R01ES031979 | Adv Pharmacol (2023) |
36858775
|
2023 |
| chi sequences switch the RecBCD helicase-nuclease complex from degradative to replicative modes duri ... | Hamilton, Nicklas A; Jehru, Avery E; Samples, William N; Wendel, Brian M; Mokhtari, Parisa D; C ... | R21ES034880 | J Biol Chem (2023 Mar) |
36781123
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2023 |
| Context-aware single-cell multiome approach identified cell-type specific lung cancer susceptibility ... | Long, Erping; Yin, Jinhu; Shin, Ju Hye; Li, Yuyan; Kane, Alexander; Patel, Harsh; Luong, Thon ... | R00ES033259 | bioRxiv (2023 Sep 26) |
37808664
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2023 |
| Could senescence phenotypes strike the balance to promote tumor dormancy? | Chiu, Fang-Yen; Kvadas, Raegan M; Mheidly, Zeinab; Shahbandi, Ashkan; Jackson, James G | R01ES032036 | Cancer Metastasis Rev (2023 Mar) |
36735097
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2023 |
| Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester trans ... | Afsar, Mohammad; Liu, GuanQun; Jia, Lijia; Ruben, Eliza A; Nayak, Digant; Sayyad, Zuberwasim; ... | R01ES007061 | Nat Commun (2023 Aug 08) |
37553340
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2023 |
| Detecting recurrent passenger mutations in melanoma by targeted UV damage sequencing. | Selvam, Kathiresan; Sivapragasam, Smitha; Poon, Gregory M K; Wyrick, John J | R01ES028698, R01ES032814, R21ES035139 | Nat Commun (2023 May 11) |
37169747
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2023 |
| DICER ribonuclease removes harmful R-loops. | Camino, Lola P; Dutta, Arijit; Barroso, Sonia; Pérez-Calero, Carmen; Katz, Jeffrey N; García-Ru ... | R01ES007061 | Mol Cell (2023 Oct 19) |
37827159
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2023 |
| Differing structures and dynamics of two photolesions portray verification differences by the human ... | Fu, Iwen; Geacintov, Nicholas E; Broyde, Suse | R01ES025987 | Nucleic Acids Res (2023 Dec 11) |
37933861
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2023 |
| Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription ... | Pierson Smela, Merrick D; Kramme, Christian C; Fortuna, Patrick R J; Adams, Jessica L; Su, Rui; ... | R21ES034468 | Elife (2023 Feb 21) |
36803359
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2023 |
| DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork ... | Kwon, Youngho; Rösner, Heike; Zhao, Weixing; Selemenakis, Platon; He, Zhuoling; Kawale, Ajinky ... | R01ES007061 | Nat Commun (2023 Jan 26) |
36702902
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2023 |
| DNA damage and somatic mutations in mammalian cells after irradiation with a nail polish dryer. | Zhivagui, Maria; Hoda, Areebah; Valenzuela, Noelia; Yeh, Yi-Yu; Dai, Jason; He, Yudou; Nandi, ... | R01ES030993, R01ES032547, R35ES031638 | Nat Commun (2023 Jan 17) |
36650165
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2023 |
| Drugging evolution of antibiotic resistance at a regulatory network hub. | Zhai, Yin; Pribis, John P; Dooling, Sean W; Garcia-Villada, Libertad; Minnick, P J; Xia, Jun; ... | R00ES033259 | Sci Adv (2023 Jun 23) |
37352342
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2023 |
| Dynamic conformational switching underlies TFIIH function in transcription and DNA repair and impact ... | Yu, Jina; Yan, Chunli; Dodd, Thomas; Tsai, Chi-Lin; Tainer, John A; Tsutakawa, Susan E; Ivanov ... | R01ES032786 | Nat Commun (2023 May 13) |
37179334
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2023 |
| Editorial: DNA repair and nucleic acid therapeutics in cancer. | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | NAR Cancer (2023 Sep) |
37645072
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2023 |
| Electron microscopy mapping of the DNA-binding sites of monomeric, dimeric, and multimeric KSHV RTA ... | Calhoun, Jayla C; Damania, Blossom; Griffith, Jack D; Costantini, Lindsey M | R01ES031635 | J Virol (2023 Oct 31) |
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2023 |
| Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ. | McPherson, Kerry Silva; Rizzo, Alessandro A; Erlandsen, Heidi; Chatterjee, Nimrat; Walker, Grah ... | R35ES028303 | J Biol Chem (2023 Feb) |
36592930
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2023 |
| Examining the Potential Formation of Ternary DNA Complexes with Chromium‑Cysteine, Chromium-Ascorbat ... | Marchi, Sydney; Lankford, Emma; Dorin, Bradley; Drummond, Eilidh; Thomas, Sumner C; Woski, Ste ... | R15ES033800 | Biol Trace Elem Res (2023 Oct) |
36662348
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2023 |
| Finding significance: New perspectives in variant classification of the RAD51 regulators, BRCA2 and ... | Rein, Hayley L; Bernstein, Kara A | P30ES013508, R01ES031796 | DNA Repair (Amst) (2023 Oct) |
37651978
|
2023 |
| Functional analyses of single nucleotide polymorphic variants of the DNA glycosylase NEIL1 in sub-Sa ... | Zuckerman, Jamie T; Minko, Irina G; Kant, Melis; Jaruga, Pawel; Stone, Michael P; Dizdaroglu, ... | R01ES031086 | DNA Repair (Amst) (2023 Sep) |
37517321
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2023 |
| G-quadruplex DNA contributes to RNA polymerase II-mediated 3D chromatin architecture. | Yuan, Jun; He, Xiaomei; Wang, Yinsheng | R35ES031707 | Nucleic Acids Res (2023 Sep 08) |
37427784
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2023 |
| Generation and Repair of Postreplication Gaps in Escherichia coli. | Cox, Michael M; Goodman, Myron F; Keck, James L; van Oijen, Antoine; Lovett, Susan T; Robinson, ... | R35ES028343 | Microbiol Mol Biol Rev (2023 Jun 28) |
37212693
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2023 |
| Genome-wide maps of rare and atypical UV photoproducts reveal distinct patterns of damage formation ... | Bohm, Kaitlynne A; Morledge-Hampton, Benjamin; Stevison, Scott; Mao, Peng; Roberts, Steven A; W ... | R01ES028698, R01ES032814 | Proc Natl Acad Sci U S A (2023 Mar 07) |
36853943
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2023 |
| Genome-wide maps of UVA and UVB mutagenesis in yeast reveal distinct causative lesions and mutationa ... | Laughery, Marian F; Plummer, Dalton A; Wilson, Hannah E; Vandenberg, Brittany N; Mitchell, Debr ... | R01ES028698, R01ES032814 | Genetics (2023 Jul 06) |
37170598
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2023 |
| Genotoxic effects of the major alkylation damage N7-methylguanine and methyl formamidopyrimidine. | Schmaltz, Lillian F; Koag, Myong-Chul; Kou, Yi; Zhang, Louis; Lee, Seongmin | R01ES034781 | Biochem J (2023 May 15) |
37078496
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2023 |
| Heritable changes in chromatin contacts linked to transgenerational obesity. | Blumberg, Bruce; Cheng-An Chang, Richard; Egusquiza, Riann; Amato, Angélica; Li, Zhuorui; Joloy ... | R01ES023316, R01ES023316, R21ES034468 | Res Sq (2023 Nov 28) |
38077066
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2023 |
| High-Field Asymmetric Waveform Ion Mobility Spectrometry Analysis of Carcinogenic Aromatic Amines in ... | Konorev, Dmitri; Bellamri, Medjda; Wu, Chia-Fang; Wu, Ming-Tsang; Turesky, Robert J | R01ES030559 | Chem Res Toxicol (2023 Aug 21) |
37462928
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2023 |
| Hypomorphic Brca2 and Rad51c double mutant mice display Fanconi anemia, cancer and polygenic replica ... | Tomaszowski, Karl-Heinz; Roy, Sunetra; Guerrero, Carolina; Shukla, Poojan; Keshvani, Caezaan; C ... | R01ES029680 | Nat Commun (2023 Mar 11) |
36906610
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2023 |
| Implicit and Explicit Dehumanization of Older Family Members: Novel Determinants of Elder Abuse Proc ... | Chang, E-Shien; Monin, Joan K; Isenberg, Naomi; Zelterman, Daniel; Levy, Becca R | R01ES005775 | Stigma Health (2023 Feb) |
37092028
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2023 |
| In vitro DNA repair genomics using XR-seq with Escherichia coli and mammalian cell-free extracts. | Cao, Xuemei; Kose, Cansu; Selby, Christopher P; Sancar, Aziz | R01ES033414 | Proc Natl Acad Sci U S A (2023 Oct 24) |
37844222
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2023 |
| Incorporation of inosine into DNA by human polymerase eta (Polη): kinetics of nucleotide misincorpor ... | Zhang, Qi; Tretyakova, Natalia | R01ES023350 | Biochem J (2023 Sep 27) |
37746864
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2023 |
| Investigation into Propolis Components Responsible for Inducing Skin Allergy: Air Oxidation of Caffe ... | Ndreu, Lorena; Hurben, Alexander K; Nyman, Gunnar S A; Tretyakova, Natalia Y; Karlsson, Isabell ... | R01ES023350 | Chem Res Toxicol (2023 Jun 19) |
37184291
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2023 |
| Large-scale heparin-based bind-and-elute chromatography identifies two biologically distinct populat ... | Zhou, Yijun; Yuan, Runjie; Cone, Allaura S; Shifflett, Kyle W; Arias, Gabriel F; Peng, Alice; ... | R01ES031635 | J Extracell Vesicles (2023 Jun) |
37272197
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2023 |
| Letter to the Editor regarding "DNA photoproducts released by repair in biological fluids as biomark ... | Cooke, Marcus S; Hu, Chiung-Wen; Chao, Mu-Rong; Chang, Yuan-Jhe; Rhodes, Lesley E; Evans, Mark ... | R01ES030557 | Anal Bioanal Chem (2023 Jan) |
36376715
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2023 |
| m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration. | Sun, Yuxiang; Dai, Hui; Dai, Xiaoxia; Yin, Jiekai; Cui, Yuxiang; Liu, Xiaochuan; Gonzalez, Gw ... | R35ES031707 | Nature (2023 Nov) |
37938769
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2023 |
| Maintaining chromosome and genome stability by the RPA-RNF20-SNF2H cascade. | Driscoll, Garrett; Yan, Shan | R21ES032966 | Proc Natl Acad Sci U S A (2023 Jun 13) |
37276422
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2023 |
| Mammalian telomeric RNA (TERRA) can be translated to produce valine-arginine and glycine-leucine dip ... | Al-Turki, Taghreed M; Griffith, Jack D | R01ES031635 | Proc Natl Acad Sci U S A (2023 Feb 28) |
36812212
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2023 |
| Manganese transporters regulate the resumption of replication in hydrogen peroxide-stressed Escheric ... | Wang, Natalie E; Courcelle, Eleanor J; Coltman, Samantha M; Spolek, Raymond L; Courcelle, Justi ... | R21ES034880 | Biometals (2023 Dec) |
37493920
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2023 |
| Mass Spectrometry for Assessing Protein-Nucleic Acid Interactions. | He, Xiaomei; Chen, Xingyuan; Wang, Yinsheng | R35ES031707 | Anal Chem (2023 Jan 10) |
36625126
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2023 |
| Molecular mechanisms of nucleolar DNA damage checkpoint response. | Li, Jia; Yan, Shan | R21ES032966 | Trends Cell Biol (2023 May) |
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2023 |
| Molecular Mechanisms of Transcription-Coupled Repair. | Selby, Christopher P; Lindsey-Boltz, Laura A; Li, Wentao; Sancar, Aziz | R00ES030015, R01ES033414 | Annu Rev Biochem (2023 Jun 20) |
37001137
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2023 |
| Multi-step processing of replication stress-derived nascent strand DNA gaps by MRE11 and EXO1 nuclea ... | Hale, Anastasia; Dhoonmoon, Ashna; Straka, Joshua; Nicolae, Claudia M; Moldovan, George-Lucian | R01ES026184 | Nat Commun (2023 Oct 07) |
37805499
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2023 |
| Mutations in AcrR and RNA Polymerase Confer High-Level Resistance to Psoralen-UVA Irradiation. | Worley, Travis K; Weber, Emma A; Acott, Jedidiah D; Shimpi, Rahul S; Cole, Jessica M; Courcelle ... | R21ES034880 | J Bacteriol (2023 Jun 27) |
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2023 |
| Nucleotide excision repair in Human cell lines lacking both XPC and CSB proteins. | Lindsey-Boltz, Laura A; Yang, Yanyan; Kose, Cansu; Deger, Nazli; Eynullazada, Khagani; Kawara, ... | R01ES033414 | Nucleic Acids Res (2023 Jul 07) |
37144462
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2023 |
| Nucleotide Excision Repair of Aflatoxin-induced DNA Damage within the 3D Human Genome Organization. | Wu, Yiran; Adeel, Muhammad Muzammal; Sancar, Aziz; Li, Wentao | R00ES030015, R01ES033414 | bioRxiv (2023 Sep 29) |
37808841
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2023 |
| Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA dama ... | Al-Rahahleh, Rasha Q; Saville, Kate M; Andrews, Joel F; Wu, Zhijin; Koczor, Christopher A; Sobo ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | bioRxiv (2023 Dec 29) |
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2023 |
| Parallel-reaction monitoring revealed altered expression of a number of epitranscriptomic reader, wr ... | Qi, Tianyu F; Tang, Feng; Yin, Jiekai; Miao, Weili; Wang, Yinsheng | R35ES031707 | Proteomics (2023 Feb) |
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2023 |
| Phase Separation Modulates the Formation and Stabilities of DNA Guanine Quadruplex. | Gao, Zi; Yuan, Jun; He, Xiaomei; Wang, Handing; Wang, Yinsheng | R35ES031707 | JACS Au (2023 Jun 26) |
37388701
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2023 |
| Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without ... | Koczor, Christopher A; Thompson, Marlo K; Sharma, Nidhi; Prakash, Aishwarya; Sobol, Robert W | P01ES028949, R01ES030084, R44ES032522, U01ES029518, U01ES029518 | DNA Repair (Amst) (2023 Mar) |
36702010
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2023 |
| Preservation of circadian rhythm in hepatocellular cancer. | Yang, Yanyan; Abdo, Ashraf N; Kawara, Hiroaki; Selby, Christopher P; Sancar, Aziz | R01ES033414 | J Biol Chem (2023 Oct) |
37714462
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2023 |
| Promoter R-Loops Recruit U2AF1 to Modulate Its Phase Separation and RNA Splicing. | He, Xiaomei; Yuan, Jun; Gao, Zi; Wang, Yinsheng | R35ES031707 | J Am Chem Soc (2023 Oct 04) |
37733759
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2023 |
| Proximity Proteomics Revealed Aberrant mRNA Splicing Elicited by ALS-Linked Profilin-1 Mutants. | Wei, Songbo; Yang, YenYu; Wang, Yinsheng | R35ES031707 | Anal Chem (2023 Oct 17) |
37787459
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2023 |
| Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage. | Koczor, Christopher A; Saville, Kate M; Al-Rahahleh, Rasha Q; Andrews, Joel F; Li, Jianfeng; So ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Methods Mol Biol (2023) |
36515828
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2023 |
| RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles. | Longo, Michael A; Roy, Sunetra; Chen, Yue; Tomaszowski, Karl-Heinz; Arvai, Andrew S; Pepper, J ... | R01ES029680 | Nat Commun (2023 Jul 24) |
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2023 |
| Randomized Trial of Olaparib With or Without Cediranib for Metastatic Castration-Resistant Prostate ... | Kim, Joseph W; McKay, Rana R; Radke, Marc R; Zhao, Shilin; Taplin, Mary-Ellen; Davis, Nancy B; ... | R01ES005775 | J Clin Oncol (2023 Feb 01) |
36256912
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2023 |
| Rapid profiling of DNA replication dynamics using mass spectrometry-based analysis of nascent DNA. | Ashour, Mohamed E; Byrum, Andrea K; Meroni, Alice; Xia, Jun; Singh, Saurabh; Galletto, Roberto ... | R00ES033259 | J Cell Biol (2023 Apr 03) |
36795402
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2023 |
| RecA and SSB genome-wide distribution in ssDNA gaps and ends in Escherichia coli. | Pham, Phuong; Wood, Elizabeth A; Cox, Michael M; Goodman, Myron F | R35ES028343 | Nucleic Acids Res (2023 Jun 23) |
37070184
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2023 |
| Replication DNA polymerases, genome instability and cancer therapies. | Strauss, Juliet D; Pursell, Zachary F | R01ES028271 | NAR Cancer (2023 Sep) |
37388540
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2023 |
| REV7 Monomer Is Unable to Participate in Double Strand Break Repair and Translesion Synthesis but Su ... | Vassel, Faye M; Laverty, Daniel J; Bian, Ke; Piett, Cortt G; Hemann, Michael T; Walker, Graham ... | P30ES000002, R35ES028303, T32ES007020 | Int J Mol Sci (2023 Oct 31) |
37958783
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2023 |
| Revisiting the use of structural similarity index in Hi-C. | Lee, Hanjun; Blumberg, Bruce; Lawrence, Michael S; Shioda, Toshihiro | R21ES034468 | Nat Genet (2023 Dec) |
38052962
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2023 |
| RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5. | Lee, Hyemin; Jung, Ji Hoon; Ko, Hyun Min; Park, Heewon; Segall, Allyson M; Sheffmaker, Roger L ... | R01ES032036 | Proc Natl Acad Sci U S A (2023 Dec 05) |
38032932
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2023 |
| Rpb7 represses transcription-coupled nucleotide excision repair. | Gong, Wenzhi; Li, Shisheng | R03ES033789, R03ES033789 | J Biol Chem (2023 Aug) |
37380080
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2023 |
| Self-reversal facilitates the resolution of HMCES DNA-protein crosslinks in cells. | Rua-Fernandez, Jorge; Lovejoy, Courtney A; Mehta, Kavi P M; Paulin, Katherine A; Toudji, Yasmin ... | R00ES034058, R01ES030575 | Cell Rep (2023 Nov 28) |
37950866
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2023 |
| Self-reversal facilitates the resolution of HMCES-DNA protein crosslinks in cells. | Rua-Fernandez, Jorge; Lovejoy, Courtney A; Mehta, Kavi P M; Paulin, Katherine A; Toudji, Yasmin ... | R01ES030575 | bioRxiv (2023 Jun 14) |
37398432
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2023 |
| Single-molecule analysis of DNA-binding proteins from nuclear extracts (SMADNE). | Schaich, Matthew A; Schnable, Brittani L; Kumar, Namrata; Roginskaya, Vera; Jakielski, Rachel C ... | R35ES031638 | Nucleic Acids Res (2023 Apr 24) |
36861323
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2023 |
| Single-molecule analysis of purified proteins and nuclear extracts: insights from 8-oxoguanine glyco ... | Schaich, Matthew A; Weaver, Tyler M; Roginskaya, Vera; Freudenthal, Bret D; Van Houten, Bennett | R35ES031638 | bioRxiv (2023 Nov 02) |
37961208
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2023 |
| Single-molecule visualization of Pif1 helicase translocation on single-stranded DNA. | Mustafi, Mainak; Kwon, Youngho; Sung, Patrick; Greene, Eric C | R01ES007061 | J Biol Chem (2023 Jun) |
37178921
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2023 |
| Spontaneous allelic variant in deafness-blindness gene Ush1g resulting in an expanded phenotype. | Vartanian, Vladimir; Krey, Jocelyn F; Chatterjee, Paroma; Curtis, Allison; Six, Makayla; Rice, ... | R01ES031086 | Genes Brain Behav (2023 Aug) |
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2023 |
| Structural insights into BCDX2 complex function in homologous recombination. | Rawal, Yashpal; Jia, Lijia; Meir, Aviv; Zhou, Shuo; Kaur, Hardeep; Ruben, Eliza A; Kwon, Youn ... | P30ES013508, R01ES007061, R01ES030335, R01ES031796 | Nature (2023 Jul) |
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2023 |
| Telomere Fragility and MiDAS: Managing the Gaps at the End of the Road. | Barnes, Ryan P; Thosar, Sanjana A; Opresko, Patricia L | R35ES030396 | Genes (Basel) (2023 Jan 29) |
36833275
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2023 |
| The Mfd protein is the transcription-repair coupling factor (TRCF) in Mycobacterium smegmatis. | Adebali, Ogun; Yang, Yanyan; Neupane, Pradeep; Dike, Nneka I; Boltz, Julia L; Kose, Cansu; Bra ... | R01ES033414 | J Biol Chem (2023 Mar) |
36775124
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2023 |
| Transcription-Replication Conflicts as a Source of Genome Instability. | Goehring, Liana; Huang, Tony T; Smith, Duncan J | R01ES031658 | Annu Rev Genet (2023 Nov 27) |
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2023 |
| Translating the telomeres. | De Rosa, Mariarosaria; Opresko, Patricia L | R35ES030396 | Trends Genet (2023 Aug) |
37179160
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2023 |
| Ubiquitin signaling and the proteasome drive human DNA-protein crosslink repair. | Essawy, Maram; Chesner, Lisa; Alshareef, Duha; Ji, Shaofei; Tretyakova, Natalia; Campbell, Col ... | R01ES023350 | Nucleic Acids Res (2023 Dec 11) |
37843153
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2023 |
| Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-depende ... | Wan, Li; Toland, Sabrina; Robinson-McCarthy, Lindsey R; Lee, Nara; Schaich, Matthew A; Hengel, ... | R00ES033738, R01ES030335, R01ES031796, R35ES031638 | Proc Natl Acad Sci U S A (2023 Jul 25) |
37459531
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2023 |
| UV damage induces production of mitochondrial DNA fragments with specific length profiles. | Waneka, Gus; Stewart, Joseph; Anderson, John R; Li, Wentao; Wilusz, Jeffrey; Argueso, Juan Luc ... | R00ES030015 | bioRxiv (2023 Nov 11) |
37986892
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2023 |
| UV irradiation remodels the specificity landscape of transcription factors. | Mielko, Zachery; Zhang, Yuning; Sahay, Harshit; Liu, Yiling; Schaich, Matthew A; Schnable, Bri ... | R35ES031638 | Proc Natl Acad Sci U S A (2023 Mar 14) |
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2023 |
| UV light-induced dual promoter mutations dismantle the telomeric guardrails in melanoma. | Sanford, Samantha L; Opresko, Patricia L | R35ES030396 | DNA Repair (Amst) (2023 Feb) |
36603239
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2023 |
| UV-DDB as a General Sensor of DNA Damage in Chromatin: Multifaceted Approaches to Assess Its Direct ... | Raja, Sripriya J; Van Houten, Bennett | R35ES031638 | Int J Mol Sci (2023 Jun 15) |
37373320
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2023 |
| UV-DDB stimulates the activity of SMUG1 during base excision repair of 5-hydroxymethyl-2'-deoxyuridi ... | Jang, Sunbok; Raja, Sripriya J; Roginskaya, Vera; Schaich, Matthew A; Watkins, Simon C; Van Hou ... | R35ES031638 | Nucleic Acids Res (2023 Jun 09) |
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2023 |
| Visualizing DNA replication by single-molecule analysis of replicated DNA. | Madireddy, Advaitha; Gerhardt, Jeannine | R01ES034733 | STAR Protoc (2023 Dec 15) |
38048218
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| WRN suppresses p53/PUMA-induced apoptosis in colorectal cancer with microsatellite instability/misma ... | Sobol, Robert W | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Proc Natl Acad Sci U S A (2023 Jan 10) |
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2023 |
| A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular res ... | Li, Jianfeng; Beiser, Alison; Dey, Nupur B; Takeda, Shunichi; Saha, Liton Kumar; Hirota, Kouji ... | R44ES032522, U01ES029518, U01ES029518 | NAR Genom Bioinform (2022 Sep) |
36110898
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2022 |
| A Human MSH6 Germline Variant Associated With Systemic Lupus Erythematosus Induces Lupus-like Diseas ... | Meas, Rithy; Nititham, Joanne; Taylor, Kimberly E; Maher, Stephen; Clairmont, Kaylyn; Carufe, ... | R35ES031708 | ACR Open Rheumatol (2022 Sep) |
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2022 |
| A new technique for genome-wide mapping of nucleotide excision repair without immunopurification of ... | Wu, Sizhong; Huang, Yanchao; Selby, Christopher P; Gao, Meng; Sancar, Aziz; Hu, Jinchuan | P30ES010126, R01ES033414 | J Biol Chem (2022 May) |
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2022 |
| Aha1 Is an Autonomous Chaperone for SULT1A1. | Liu, Xiaochuan; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2022 Aug 15) |
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| Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Modulate miRNA Biogenesis through Aberrant ... | Chen, Xingyuan; He, Xiaomei; Yang, Yen-Yu; Wang, Yinsheng | R35ES031707 | ACS Chem Biol (2022 Dec 16) |
36475596
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2022 |
| APE1 assembles biomolecular condensates to promote the ATR-Chk1 DNA damage response in nucleolus. | Li, Jia; Zhao, Haichao; McMahon, Anne; Yan, Shan | R21ES032966 | Nucleic Acids Res (2022 Oct 14) |
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| Bayesian local exchangeability design for phase II basket trials. | Liu, Yilin; Kane, Michael; Esserman, Denise; Blaha, Ondrej; Zelterman, Daniel; Wei, Wei | R01ES005775 | Stat Med (2022 Sep 30) |
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2022 |
| Biochemical Analysis of RNA-DNA Hybrid and R-Loop Unwinding Via Motor Proteins. | Dutta, Arijit; Kwon, Youngho; Sung, Patrick | R01ES007061 | Methods Mol Biol (2022) |
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2022 |
| Bloom helicase mediates formation of large single-stranded DNA loops during DNA end processing. | Xue, Chaoyou; Salunkhe, Sameer J; Tomimatsu, Nozomi; Kawale, Ajinkya S; Kwon, Youngho; Burma, ... | R01ES007061 | Nat Commun (2022 Apr 26) |
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2022 |
| Breast cancer cells survive chemotherapy by activating targetable immune-modulatory programs charact ... | Shahbandi, Ashkan; Chiu, Fang-Yen; Ungerleider, Nathan A; Kvadas, Raegan; Mheidly, Zeinab; Sun, ... | R01ES028271, R01ES032036 | Nat Cancer (2022 Dec) |
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| Chemoproteomic Approach for the Quantitative Identification of Arsenic-Binding Proteins. | Dong, Xuejiao; Wang, Pengcheng; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2022 Nov 21) |
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| Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identif ... | Khatib, Jude B; Schleicher, Emily M; Jackson, Lindsey M; Dhoonmoon, Ashna; Moldovan, George-Luc ... | R01ES026184 | Oncotarget (2022) |
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| Cooperative interaction between AAG and UV-DDB in the removal of modified bases. | Jang, Sunbok; Kumar, Namrata; Schaich, Mathew A; Zhong, Zhou; van Loon, Barbara; Watkins, Simo ... | R35ES031638 | Nucleic Acids Res (2022 Dec 09) |
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2022 |
| CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery. | Schleicher, Emily M; Moldovan, George-Lucian | R01ES026184 | FEBS J (2022 Dec) |
34601817
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2022 |
| Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new suscept ... | Byun, Jinyoung; Han, Younghun; Li, Yafang; Xia, Jun; Long, Erping; Choi, Jiyeon; Xiao, Xiangj ... | R00ES033259, T32ES027801 | Nat Genet (2022 Aug) |
35915169
|
2022 |
| CSB-independent, XPC-dependent transcription-coupled repair in Drosophila. | Deger, Nazli; Cao, Xuemei; Selby, Christopher P; Gulec, Saygin; Kawara, Hiroaki; Dewey, Evan B ... | R01ES033414 | Proc Natl Acad Sci U S A (2022 Mar 01) |
35217627
|
2022 |
| Cyclobutane Pyrimidine Dimer Hyperhotspots as Sensitive Indicators of Keratinocyte UV Exposure†. | Garcia-Ruiz, Alejandro; Kornacker, Karl; Brash, Douglas E | R01ES030562 | Photochem Photobiol (2022 Sep) |
35944237
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2022 |
| Damage mapping techniques and the light they have shed on canonical and atypical UV photoproducts. | Bohm, Kaitlynne A; Wyrick, John J | R01ES028698, R01ES032814 | Front Genet (2022) |
36704334
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2022 |
| dCas9 binding inhibits the initiation of base excision repair in vitro. | Antony, Jacob S; Roberts, Steven A; Wyrick, John J; Hinz, John M | R01ES028698 | DNA Repair (Amst) (2022 Jan) |
34847381
|
2022 |
| DNA Damage and Oxidative Stress of Tobacco Smoke Condensate in Human Bladder Epithelial Cells. | Bellamri, Medjda; Walmsley, Scott J; Brown, Christina; Brandt, Kyle; Konorev, Dmitri; Day, Abd ... | R01ES030559 | Chem Res Toxicol (2022 Oct 17) |
35877975
|
2022 |
| Double-strand breaks: When DNA repair events accidentally meet. | Fujii, Shingo; Sobol, Robert W; Fuchs, Robert P | P01ES028949, U01ES029518, U01ES029518 | DNA Repair (Amst) (2022 Apr) |
35219626
|
2022 |
| Editorial: Mechanistic studies of genome integrity, environmental health, and cancer etiology. | Yan, Shan; Zhao, Jianjun; Kemp, Michael; Sobol, Robert W | R21ES032966 | Front Cell Dev Biol (2022) |
36247007
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2022 |
| Effects of replication domains on genome-wide UV-induced DNA damage and repair. | Huang, Yanchao; Azgari, Cem; Yin, Mengdie; Chiou, Yi-Ying; Lindsey-Boltz, Laura A; Sancar, Azi ... | P30ES010126, R01ES033414 | PLoS Genet (2022 Sep) |
36155646
|
2022 |
| Enhanced polymerase activity permits efficient synthesis by cancer-associated DNA polymerase ϵ varia ... | Barbari, Stephanie R; Beach, Annette K; Markgren, Joel G; Parkash, Vimal; Moore, Elizabeth A; J ... | R01ES015869 | Nucleic Acids Res (2022 Aug 12) |
35822874
|
2022 |
| Epigenetic Regulation of Nucleotide Excision Repair. | Li, Wentao; Jones, Kyle; Burke, Tyler J; Hossain, Md Akram; Lariscy, Leah | R00ES030015 | Front Cell Dev Biol (2022) |
35465333
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2022 |
| Establishing Linkages Among DNA Damage, Mutagenesis, and Genetic Diseases. | Basu, Ashis K; Essigmann, John M | P42ES027707, R01ES023350 | Chem Res Toxicol (2022 Oct 17) |
35881568
|
2022 |
| Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angio ... | McNamara, Ryan P; Eason, Anthony B; Zhou, Yijun; Bigi, Rachele; Griffith, Jack D; Costantini, ... | R01ES031635 | ACS Bio Med Chem Au (2022 Apr 20) |
35480227
|
2022 |
| Facile preparation of model DNA interstrand cross-link repair intermediates using ribonucleotide-con ... | Tang, Jin; Tang, Feng; Zhao, Linlin | R35ES031707 | DNA Repair (Amst) (2022 Mar) |
35124371
|
2022 |
| Genome-wide Excision Repair Map of Cyclobutane Pyrimidine Dimers in Arabidopsis and the Roles of CSA ... | Kaya, Sezgi; Adebali, Ogun; Oztas, Onur; Sancar, Aziz | R01ES033414 | Photochem Photobiol (2022 May) |
34525225
|
2022 |
| Genomic landscape of single-stranded DNA gapped intermediates in Escherichia coli. | Pham, Phuong; Shao, Yijun; Cox, Michael M; Goodman, Myron F | R35ES028343 | Nucleic Acids Res (2022 Jan 25) |
34951472
|
2022 |
| Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair protein ... | Kumar, Namrata; Theil, Arjan F; Roginskaya, Vera; Ali, Yasmin; Calderon, Michael; Watkins, Sim ... | R35ES030396, R35ES031638 | Nat Commun (2022 Feb 21) |
35190564
|
2022 |
| Heat Shock Proteins and HSF1 in Cancer. | Cyran, Anna M; Zhitkovich, Anatoly | R01ES028072, R01ES031002, R01ES031979 | Front Oncol (2022) |
35311075
|
2022 |
| HIF1, HSF1, and NRF2: Oxidant-Responsive Trio Raising Cellular Defenses and Engaging Immune System. | Cyran, Anna M; Zhitkovich, Anatoly | R01ES028072, R01ES031002, R01ES031979 | Chem Res Toxicol (2022 Oct 17) |
35948068
|
2022 |
| High-resolution mapping demonstrates inhibition of DNA excision repair by transcription factors. | Duan, Mingrui; Sivapragasam, Smitha; Antony, Jacob S; Ulibarri, Jenna; Hinz, John M; Poon, Gre ... | R01ES028698, R01ES032814 | Elife (2022 Mar 15) |
35289750
|
2022 |
| Homologous recombination-deficient mutation cluster in tumor suppressor RAD51C identified by compreh ... | Prakash, Rohit; Rawal, Yashpal; Sullivan, Meghan R; Grundy, McKenzie K; Bret, Hélène; Mihalevic ... | R01ES007061, R01ES031796 | Proc Natl Acad Sci U S A (2022 Sep 20) |
36099300
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2022 |
| Host cell RecA activates a mobile element-encoded mutagenic DNA polymerase. | Ojha, Debika; Jaszczur, Malgorzata M; Sikand, Adhirath; McDonald, John P; Robinson, Andrew; van ... | R35ES028343 | Nucleic Acids Res (2022 Jul 08) |
35736210
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2022 |
| Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand cros ... | Luong, Thong T; Li, Zheqi; Priedigkeit, Nolan; Parker, Phoebe S; Böhm, Stefanie; Rapchak, Kyle ... | R01ES030335 | PLoS Genet (2022 Sep) |
36126066
|
2022 |
| HSP90 and Aha1 modulate microRNA maturation through promoting the folding of Dicer1. | Liu, Xiaochuan; Yang, Yen-Yu; Wang, Yinsheng | R35ES031707 | Nucleic Acids Res (2022 Jul 08) |
35736213
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2022 |
| Imaging of surface microdomains on individual extracellular vesicles in 3-D. | McNamara, Ryan P; Zhou, Yijun; Eason, Anthony B; Landis, Justin T; Chambers, Meredith G; Willco ... | R01ES031635 | J Extracell Vesicles (2022 Mar) |
35234354
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2022 |
| Immunoglobulin somatic hypermutation in a defined biochemical system recapitulates affinity maturati ... | Jeong, Soo Lim; Zhang, Hongyu; Yamaki, Shanni; Yang, Chenyu; McKemy, David D; Lieber, Michael ... | R35ES028343 | Nucleic Acids Res (2022 Nov 11) |
36321646
|
2022 |
| Inhibition of E. coli RecQ Helicase Activity by Structurally Distinct DNA Lesions: Structure-Functio ... | Sales, Ana H; Zheng, Vincent; Kenawy, Maya A; Kakembo, Mark; Zhang, Lu; Shafirovich, Vladimir; ... | R01ES025987 | Int J Mol Sci (2022 Dec 09) |
36555294
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2022 |
| Interlocking activities of DNA polymerase β in the base excision repair pathway. | Kumar, Adarsh; Reed, Andrew J; Zahurancik, Walter J; Daskalova, Sasha M; Hecht, Sidney M; Suo, ... | R01ES028271 | Proc Natl Acad Sci U S A (2022 Mar 08) |
35238634
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2022 |
| Lagging strand gap suppression connects BRCA-mediated fork protection to nucleosome assembly through ... | Thakar, Tanay; Dhoonmoon, Ashna; Straka, Joshua; Schleicher, Emily M; Nicolae, Claudia M; Moldo ... | R01ES026184 | Nat Commun (2022 Sep 09) |
36085347
|
2022 |
| Live Cell Detection of Poly(ADP-Ribose) for Use in Genetic and Genotoxic Compound Screens. | Koczor, Christopher A; Haider, Aaron J; Saville, Kate M; Li, Jianfeng; Andrews, Joel F; Beiser, ... | P01ES028949, R44ES032522, U01ES029518, U01ES029518 | Cancers (Basel) (2022 Jul 28) |
35954352
|
2022 |
| Mapping atypical UV photoproducts in vitro and across the S. cerevisiae genome. | Bohm, Kaitlynne A; Sivapragasam, Smitha; Wyrick, John J | R01ES028698, R01ES032814 | STAR Protoc (2022 Mar 18) |
35005641
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2022 |
| Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair. | Fu, Iwen; Mu, Hong; Geacintov, Nicholas E; Broyde, Suse | R01ES025987 | Nucleic Acids Res (2022 Jul 08) |
35713557
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2022 |
| Mechanisms of PARP1 inhibitor resistance and their implications for cancer treatment. | Jackson, Lindsey M; Moldovan, George-Lucian | R01ES026184 | NAR Cancer (2022 Dec) |
36568963
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2022 |
| Molecular mechanism of UV damage modulation in nucleosomes. | Stark, Bastian; Poon, Gregory M K; Wyrick, John J | R01ES028698, R01ES032814 | Comput Struct Biotechnol J (2022) |
36212527
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2022 |
| N-Methyl-N-nitrosourea Induced 3'-Glutathionylated DNA-Cleavage Products in Mammalian Cells. | Yin, Jiekai; Gates, Kent S; Wang, Yinsheng | R01ES021007 | Anal Chem (2022 Nov 15) |
36332130
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2022 |
| Novel interaction interfaces mediate the interaction between the NEIL1 DNA glycosylase and mitochond ... | Sharma, Nidhi; Thompson, Marlo K; Arrington, Jennifer F; Terry, Dava M; Chakravarthy, Srinivas; ... | R01ES030084, R35ES031708 | Front Cell Dev Biol (2022) |
35938152
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2022 |
| NT-seq: a chemical-based sequencing method for genomic methylome profiling. | Li, Xuwen; Guo, Shiyuan; Cui, Yan; Zhang, Zijian; Luo, Xinlong; Angelova, Margarita T; Landweb ... | R35ES031707 | Genome Biol (2022 May 30) |
35637459
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2022 |
| Nucleotide excision repair removes thymidine analog 5-ethynyl-2'-deoxyuridine from the mammalian gen ... | Wang, Li; Cao, Xuemei; Yang, Yanyan; Kose, Cansu; Kawara, Hiroaki; Lindsey-Boltz, Laura A; Sel ... | P30ES010126, R01ES033414 | Proc Natl Acad Sci U S A (2022 Aug 30) |
35994676
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2022 |
| Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone. | Coley, Alexander B; Ward, Antonio; Keeton, Adam B; Chen, Xi; Maxuitenko, Yulia; Prakash, Aishw ... | R35ES031708 | Adv Cancer Res (2022) |
35101229
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2022 |
| Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms. | Ledford, Benjamin T; Akerman, Adam W; Sun, Kui; Gillis, David C; Weiss, Jenna M; Vang, Johnny; ... | R01ES031635 | ACS Nano (2022 May 24) |
35504018
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2022 |
| Perspectives on Cyclobutane Pyrimidine Dimers-Rise of the Dark Dimers. | Lawrence, Karl P; Delinasios, George J; Premi, Sanjay; Young, Antony R; Cooke, Marcus S | R01ES030557 | Photochem Photobiol (2022 05) |
34706095
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2022 |
| Phosphoinositide species and filamentous actin formation mediate engulfment by senescent tumor cells ... | Frey, Wesley D; Anderson, Ashlyn Y; Lee, Hyemin; Nguyen, Julie B; Cowles, Emma L; Lu, Hua; Jac ... | R01ES032036 | PLoS Biol (2022 Oct) |
36279312
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2022 |
| Photocaged dicarbonyl probe provides spatiotemporal control over protein glycation. | Hurben, Alexander K; Ge, Peng; Bouchard, Jacob L; Doran, Todd M; Tretyakova, Natalia Y | R01ES023350 | Chem Commun (Camb) (2022 Jan 18) |
34935009
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2022 |
| PMS2 variant results in loss of ATPase activity without compromising mismatch repair. | D'Arcy, Brandon M; Arrington, Jennifer; Weisman, Justin; McClellan, Steven B; Vandana; Yang, Zh ... | R01ES030084, R35ES031708 | Mol Genet Genomic Med (2022 Feb 21) |
35189042
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2022 |
| Polymerase η Recruits DHX9 Helicase to Promote Replication across Guanine Quadruplex Structures. | Tang, Feng; Wang, Yinan; Gao, Zi; Guo, Shiyuan; Wang, Yinsheng | R35ES031707 | J Am Chem Soc (2022 Aug 10) |
35905379
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2022 |
| Polymorphic variant Asp239Tyr of human DNA glycosylase NTHL1 is inactive for removal of a variety of ... | Kant, Melis; Quintana, Victoria; Coskun, Erdem; Jaruga, Pawel; Lloyd, R Stephen; Sweasy, Joann ... | R01ES031086, R35ES031708 | DNA Repair (Amst) (2022 Sep) |
35870279
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2022 |
| Premature aging is associated with higher levels of 8-oxoguanine and increased DNA damage in the Pol ... | Yu, Tenghui; Slone, Jesse; Liu, Wensheng; Barnes, Ryan; Opresko, Patricia L; Wark, Landon; Mai ... | R35ES030396 | Aging Cell (2022 Sep) |
35993394
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2022 |
| Processing oxidatively damaged bases at DNA strand breaks by APE1. | Whitaker, Amy M; Stark, Wesley J; Freudenthal, Bret D | R00ES031148 | Nucleic Acids Res (2022 Sep 09) |
36018803
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2022 |
| Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Ins ... | Jha, Jay S; Nel, Christopher; Haldar, Tuhin; Peters, Daniel; Housh, Kurt; Gates, Kent S | R01ES021007 | Chem Res Toxicol (2022 Feb 21) |
35124963
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2022 |
| Quantitative Assessment of Arsenite-Induced Perturbation of Ubiquitinated Proteome. | Jiang, Ji; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2022 Sep 19) |
35994080
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2022 |
| Quantitative proteomics revealed new functions of ALKBH4. | Yu, Kailin; Qi, Tianyu F; Miao, Weili; Liu, Xiaochuan; Wang, Yinsheng | R35ES031707 | Proteomics (2022 Apr) |
34951099
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2022 |
| RAD51AP1 and RAD54L Can Underpin Two Distinct RAD51-Dependent Routes of DNA Damage Repair via Homolo ... | Selemenakis, Platon; Sharma, Neelam; Uhrig, Mollie E; Katz, Jeffrey; Kwon, Youngho; Sung, Patr ... | R01ES007061 | Front Cell Dev Biol (2022) |
35652094
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2022 |
| RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA. | Kaminski, Nicole; Wondisford, Anne R; Kwon, Youngho; Lynskey, Michelle Lee; Bhargava, Ragini; B ... | R01ES007061 | Mol Cell (2022 Nov 03) |
36265488
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2022 |
| Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments. | Meir, Aviv; Crickard, J Brooks; Kwon, Youngho; Sung, Patrick; Greene, Eric C | R01ES007061 | Proc Natl Acad Sci U S A (2022 Jan 25) |
35042797
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2022 |
| Recombination Mediator Proteins: Misnomers That Are Key to Understanding the Genomic Instabilities i ... | Courcelle, Justin; Worley, Travis K; Courcelle, Charmain T | R21ES034880 | Genes (Basel) (2022 Feb 27) |
35327990
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2022 |
| Reconsidering the Chemical Nature of Strand Breaks Derived from Abasic Sites in Cellular DNA: Eviden ... | Jha, Jay S; Yin, Jiekai; Haldar, Tuhin; Yang, Zhiyu; Wang, Yinsheng; Gates, Kent S | R01ES021007 | J Am Chem Soc (2022 Jun 15) |
35612610
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2022 |
| Residues located in the primase domain of the bacteriophage T7 primase-helicase are essential for lo ... | Hernandez, Alfredo J; Lee, Seung-Joo; Thompson, Noah J; Griffith, Jack D; Richardson, Charles C | R01ES031635 | J Biol Chem (2022 Jun) |
35500649
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2022 |
| Role of Protein Damage Inflicted by Dopamine Metabolites in Parkinson's Disease: Evidence, Tools, an ... | Hurben, Alexander K; Tretyakova, Natalia Y | R01ES023350 | Chem Res Toxicol (2022 Oct 17) |
35994383
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2022 |
| Set2 histone methyltransferase regulates transcription coupled-nucleotide excision repair in yeast. | Selvam, Kathiresan; Plummer, Dalton A; Mao, Peng; Wyrick, John J | R01ES028698, R01ES032814 | PLoS Genet (2022 Mar) |
35263330
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2022 |
| Structure of DNMT3B homo-oligomer reveals vulnerability to impairment by ICF mutations. | Gao, Linfeng; Guo, Yiran; Biswal, Mahamaya; Lu, Jiuwei; Yin, Jiekai; Fang, Jian; Chen, Xinyi; ... | R35ES031707 | Nat Commun (2022 Jul 22) |
35869095
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2022 |
| Targeted Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Accompanied with Radiore ... | Qi, Tianyu F; Miao, Weili; Wang, Yinsheng | R35ES031707 | Anal Chem (2022 Jan 25) |
35021009
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2022 |
| Targeted Proteomic Analysis of Small GTPases in Radioresistant Breast Cancer Cells. | Gao, Zi; Yang, Yen-Yu; Huang, Ming; Qi, Tianyu F; Wang, Handing; Wang, Yinsheng | R35ES031707, T32ES018827 | Anal Chem (2022 Nov 01) |
36264766
|
2022 |
| Targeted Quantitative Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Using Stabl ... | Qi, Tianyu F; Liu, Xiaochuan; Tang, Feng; Yin, Jiekai; Yu, Kailin; Wang, Yinsheng | R35ES031707 | Anal Chem (2022 Sep 20) |
36084281
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2022 |
| Targeting Mitochondrial Function with Chemoptogenetics. | Romesberg, Amy; Van Houten, Bennett | R35ES031638 | Biomedicines (2022 Oct 01) |
36289721
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2022 |
| Targeting Therapeutic Resistance and Multinucleate Giant Cells in CCNE1-Amplified HR-Proficient Ovar ... | Bai, Shoumei; Taylor, Sarah E; Jamalruddin, Mohd Azrin; McGonigal, Stacy; Grimley, Edward; Yang ... | R01ES031796 | Mol Cancer Ther (2022 Sep 06) |
35732503
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2022 |
| Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening. | Barnes, Ryan P; de Rosa, Mariarosaria; Thosar, Sanjana A; Detwiler, Ariana C; Roginskaya, Vera; ... | R35ES030396, R35ES031638 | Nat Struct Mol Biol (2022 Jul) |
35773409
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2022 |
| The hematopoietic compartment is sufficient for lupus development resulting from the POLB-Y265C muta ... | Rahim, Tania; Levinson, Madison A; Carufe, Kelly E W; Burak, Matthew; Meas, Rithy; Maher, Step ... | R35ES031708 | PLoS One (2022) |
35486639
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2022 |
| The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1. | Hirschler-Laszkiewicz, Iwona; Festa, Fernanda; Huang, Suming; Moldovan, George-Lucian; Nicolae, ... | R01ES026184 | Sci Rep (2022 Apr 15) |
35428820
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2022 |
| The KU-PARP14 axis differentially regulates DNA resection at stalled replication forks by MRE11 and ... | Dhoonmoon, Ashna; Nicolae, Claudia M; Moldovan, George-Lucian | R01ES026184 | Nat Commun (2022 Aug 27) |
36030235
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2022 |
| The mRNA tether model for activation-induced deaminase and its relevance for Ig somatic hypermutatio ... | Liu, Di; Goodman, Myron F; Pham, Phuong; Yu, Kefei; Hsieh, Chih-Lin; Lieber, Michael R | R35ES028343 | DNA Repair (Amst) (2022 Feb) |
34990960
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2022 |
| The role of UV-DDB in processing 8-oxoguanine during base excision repair. | Nagpal, Ashna; Raja, Sripriya; Van Houten, Bennett | R35ES031638 | Biochem Soc Trans (2022 Oct 31) |
36305644
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2022 |
| The SOS response-associated peptidase (SRAP) domain of YedK catalyzes ring opening of abasic sites a ... | Paulin, Katherine A; Cortez, David; Eichman, Brandt F | R01ES030575 | J Biol Chem (2022 Sep) |
35934051
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2022 |
| The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cells. | Schleicher, Emily M; Dhoonmoon, Ashna; Jackson, Lindsey M; Khatib, Jude B; Nicolae, Claudia M; ... | R01ES026184 | Oncogenesis (2022 Jun 18) |
35717336
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2022 |
| Tips, Tricks, and Potential Pitfalls of CRISPR Genome Editing in Saccharomyces cerevisiae. | Antony, Jacob S; Hinz, John M; Wyrick, John J | R01ES028698, R01ES032814 | Front Bioeng Biotechnol (2022) |
35706506
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2022 |
| Transcriptional Perturbations of 2,6-Diaminopurine and 2-Aminopurine. | Tan, Ying; You, Changjun; Park, Jiyeong; Kim, Hyun Suk; Guo, Su; Schärer, Orlando D; Wang, Yi ... | R35ES031707 | ACS Chem Biol (2022 Jul 15) |
35700389
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2022 |
| Unexpected Complexity in the Products Arising from NaOH-, Heat-, Amine-, and Glycosylase-Induced Str ... | Haldar, Tuhin; Jha, Jay S; Yang, Zhiyu; Nel, Christopher; Housh, Kurt; Cassidy, Orla J; Gates, ... | R01ES021007 | Chem Res Toxicol (2022 Feb 21) |
35129338
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2022 |
| USP1-trapping lesions as a source of DNA replication stress and genomic instability. | Coleman, Kate E; Yin, Yandong; Lui, Sarah Kit Leng; Keegan, Sarah; Fenyo, David; Smith, Duncan ... | R01ES031658 | Nat Commun (2022 Apr 01) |
35365626
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2022 |
| Vulnerability of HIF1α and HIF2α to damage by proteotoxic stressors. | Meyers, Lauren M; Krawic, Casey; Luczak, Michal W; Zhitkovich, Anatoly | R01ES028072, R01ES031002, R01ES031979 | Toxicol Appl Pharmacol (2022 Jun 15) |
35504338
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2022 |
| Widespread pesticide contamination of drinking water and impact on cancer risk in Brazil. | Panis, Carolina; Candiotto, Luciano Zanetti Pessôa; Gaboardi, Shaiane Carla; Gurzenda, Susie; Cr ... | R01ES027981 | Environ Int (2022 Jul) |
35691095
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2022 |
| A basal-level activity of ATR links replication fork surveillance and stress response. | Yin, Yandong; Lee, Wei Ting Chelsea; Gupta, Dipika; Xue, Huijun; Tonzi, Peter; Borowiec, James ... | R01ES031658 | Mol Cell (2021 10 21) |
34473946
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2021 |
| A Quantitative Proteomic Approach for the Identification of DNA Guanine Quadruplex-Binding Proteins. | Gao, Zi; Williams, Preston; Li, Lin; Wang, Yinsheng | R35ES031707 | J Proteome Res (2021 11 05) |
34570971
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2021 |
| Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR in ... | Grimley, Edward; Cole, Alexander J; Luong, Thong T; McGonigal, Stacy C; Sinno, Sarah; Yang, Do ... | R01ES030335, R01ES031796 | Theranostics (2021) |
33664846
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2021 |
| Alkylating and oxidative stresses in smoking and non-smoking patients with COPD: Implications for lu ... | Shih, Ying-Ming; Chang, Yuan-Jhe; Cooke, Marcus S; Pan, Chih-Hong; Hu, Ching-Hsuan; Chao, Mu-R ... | R01ES030557 | Free Radic Biol Med (2021 02 20) |
33418114
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2021 |
| APE2 Is a General Regulator of the ATR-Chk1 DNA Damage Response Pathway to Maintain Genome Integrity ... | Hossain, Md Akram; Lin, Yunfeng; Driscoll, Garrett; Li, Jia; McMahon, Anne; Matos, Joshua; Zha ... | R21ES032966 | Front Cell Dev Biol (2021) |
34796173
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2021 |
| Ascorbate: antioxidant and biochemical activities and their importance for in vitro models. | Zhitkovich, Anatoly | R01ES028072, R01ES031002, R01ES031979 | Arch Toxicol (2021 Dec) |
34596731
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2021 |
| Biomarkers of nucleic acid oxidation - A summary state-of-the-art. | Chao, Mu-Rong; Evans, Mark D; Hu, Chiung-Wen; Ji, Yunhee; Møller, Peter; Rossner, Pavel; Cooke ... | R01ES030557 | Redox Biol (2021 06) |
33579665
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2021 |
| Chaperones for dancing on chromatin: Role of post-translational modifications in dynamic damage dete ... | Van Houten, Bennett; Schnable, Brittani; Kumar, Namrata | R35ES031638 | Bioessays (2021 May) |
33620094
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2021 |
| Chemoproteomic Approach toward Probing the Interactomes of Perfluoroalkyl Substances. | Zhang, Quanqing; Dong, Xuejiao; Lu, Jiuwei; Song, Jikui; Wang, Yinsheng | R35ES031707 | Anal Chem (2021 Jul 13) |
34185510
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2021 |
| Circadian clock, carcinogenesis, chronochemotherapy connections. | Yang, Yanyan; Lindsey-Boltz, Laura A; Vaughn, Courtney M; Selby, Christopher P; Cao, Xuemei; Li ... | R01ES033414 | J Biol Chem (2021 09) |
34375638
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2021 |
| Comparative analyses of two primate species diverged by more than 60 million years show different ra ... | Akkose, Umit; Kaya, Veysel Ogulcan; Lindsey-Boltz, Laura; Karagoz, Zeynep; Brown, Adam D; Larse ... | R01ES033414 | BMC Genomics (2021 Aug 06) |
34362292
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2021 |
| Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positi ... | Stepchenkova, Elena I; Zhuk, Anna S; Cui, Jian; Tarakhovskaya, Elena R; Barbari, Stephanie R; S ... | R01ES015869 | Genetics (2021 06 24) |
33844024
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2021 |
| Comprehensive Analysis of DNA Adducts Using Data-Independent wSIM/MS2 Acquisition and wSIM-City. | Walmsley, Scott J; Guo, Jingshu; Murugan, Paari; Weight, Christopher J; Wang, Jinhua; Villalta, ... | R01ES030765, U2CES026533 | Anal Chem (2021 Apr 27) |
33844920
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2021 |
| CTCF binding modulates UV damage formation to promote mutation hot spots in melanoma. | Sivapragasam, Smitha; Stark, Bastian; Albrecht, Amanda V; Bohm, Kaitlynne A; Mao, Peng; Emehise ... | R01ES028698, R01ES032814 | EMBO J (2021 Oct 18) |
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2021 |
| CTCF puts a new twist on UV damage and repair in skin cancer. | Stark, Bastian; Poon, Gregory M K; Wyrick, John J | R01ES028698, R01ES032814 | Mol Cell Oncol (2021) |
35419468
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2021 |
| Cytotoxicity and genotoxicity of the carcinogen aristolochic acid I (AA-I) in human bladder RT4 cell ... | Bellamri, Medjda; Brandt, Kyle; Brown, Christina V; Wu, Ming-Tsang; Turesky, Robert J | R01ES030559 | Arch Toxicol (2021 Jun) |
33938965
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2021 |
| Differential immunomodulatory effect of PARP inhibition in BRCA1 deficient and competent tumor cells ... | Alvarado-Cruz, Isabel; Mahmoud, Mariam; Khan, Mohammed; Zhao, Shilin; Oeck, Sebastian; Meas, R ... | R35ES031708 | Biochem Pharmacol (2021 02) |
33285109
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2021 |
| Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex. | Prakash, Rohit; Sandoval, Thomas; Morati, Florian; Zagelbaum, Jennifer A; Lim, Pei-Xin; White, ... | R01ES030335 | Nat Commun (2021 Jul 12) |
34253720
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2021 |
| Distinct roles for RSC and SWI/SNF chromatin remodelers in genomic excision repair. | Bohm, Kaitlynne A; Hodges, Amelia J; Czaja, Wioletta; Selvam, Kathiresan; Smerdon, Michael J; M ... | R01ES028698 | Genome Res (2021 06) |
34001524
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2021 |
| DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model. | Paluri, Sesha L; Burak, Matthew; Senejani, Alireza G; Levinson, Madison; Rahim, Tania; Clairmon ... | R35ES031708 | DNA Repair (Amst) (2021 09) |
34186496
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2021 |
| DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal an ... | Chung, Jiil; Maruvka, Yosef E; Sudhaman, Sumedha; Kelly, Jacalyn; Haradhvala, Nicholas J; Bianc ... | R01ES028271 | Cancer Discov (2021 05) |
33355208
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2021 |
| DNA Polymerase II Supports the Replicative Bypass of N2-Alkyl-2'-deoxyguanosine Lesions in Escherich ... | Wang, Yinan; Wu, Jun; Wu, Jiabin; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2021 Mar 15) |
33417436
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2021 |
| DNA Polymerase η Promotes the Transcriptional Bypass of N2-Alkyl-2'-deoxyguanosine Adducts in Human ... | Tan, Ying; Guo, Su; Wu, Jun; Du, Hua; Li, Lin; You, Changjun; Wang, Yinsheng | R35ES031707 | J Am Chem Soc (2021 10 06) |
34555898
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2021 |
| DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B1-Induced Formam ... | Tomar, Rachana; Minko, Irina G; Kellum Jr, Andrew H; Voehler, Markus W; Stone, Michael P; McCul ... | R01ES031086 | Chem Res Toxicol (2021 03 15) |
33595290
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2021 |
| DNA-protein crosslinks are repaired via homologous recombination in mammalian mitochondria. | Chesner, Lisa N; Essawy, Maram; Warner, Cecilia; Campbell, Colin | R01ES023350 | DNA Repair (Amst) (2021 01) |
33316746
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2021 |
| DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation. | Ren, Wendan; Fan, Huitao; Grimm, Sara A; Kim, Jae Jin; Li, Linhui; Guo, Yiran; Petell, Christ ... | R35ES031707 | Nat Commun (2021 05 03) |
33941775
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2021 |
| Dynamic Processing of a Common Oxidative DNA Lesion by the First Two Enzymes of the Base Excision Re ... | Raper, Austin T; Maxwell, Brian A; Suo, Zucai | R01ES028271 | J Mol Biol (2021 03 05) |
33450252
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2021 |
| Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability. | Geijer, Marit E; Zhou, Di; Selvam, Kathiresan; Steurer, Barbara; Mukherjee, Chirantani; Evers, ... | R01ES028698 | Nat Cell Biol (2021 Jun) |
34108662
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2021 |
| Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to h ... | Lou, Jianlin; Yu, Shoukai; Feng, Lingfang; Guo, Xinnian; Wang, Meng; Branco, Alan T; Li, Tao; ... | P30ES000002, R01ES027981 | Environ Int (2021 08) |
33774497
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2021 |
| EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication ... | Hambarde, Shashank; Tsai, Chi-Lin; Pandita, Raj K; Bacolla, Albino; Maitra, Anirban; Charaka, ... | R01ES029680 | Mol Cell (2021 Jul 15) |
34197737
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2021 |
| Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair. | Thompson, Marlo K; Sobol, Robert W; Prakash, Aishwarya | P01ES028949, R01ES030084, R35ES031708, R44ES032522, U01ES029518, U01ES029518 | Biology (Basel) (2021 Jun 14) |
34198612
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2021 |
| Formation and Repair of an Interstrand DNA Cross-Link Arising from a Common Endogenous Lesion. | Housh, Kurt; Jha, Jay S; Yang, Zhiyu; Haldar, Tuhin; Johnson, Kevin M; Yin, Jiekai; Wang, Yin ... | R01ES021007 | J Am Chem Soc (2021 09 22) |
34516735
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2021 |
| Formation and repair of unavoidable, endogenous interstrand cross-links in cellular DNA. | Housh, Kurt; Jha, Jay S; Haldar, Tuhin; Amin, Saosan Binth Md; Islam, Tanhaul; Wallace, Amanda ... | R01ES021007 | DNA Repair (Amst) (2021 Feb) |
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2021 |
| Fused in sarcoma regulates DNA replication timing and kinetics. | Jia, Weiyan; Kim, Sang Hwa; Scalf, Mark A; Tonzi, Peter; Millikin, Robert J; Guns, William M; ... | R01ES031658 | J Biol Chem (2021 Sep) |
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2021 |
| G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities. | He, Xiaomei; Yuan, Jun; Wang, Yinsheng | R35ES031707 | Nucleic Acids Res (2021 11 08) |
34614161
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2021 |
| Genome-wide analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine at single-nucleotide resolution unveils ... | An, Jiao; Yin, Mengdie; Yin, Jiayong; Wu, Sizhong; Selby, Christopher P; Yang, Yanyan; Sancar, ... | R01ES033414 | Nucleic Acids Res (2021 12 02) |
34788860
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2021 |
| Genome-wide mapping of genomic DNA damage: methods and implications. | Amente, Stefano; Scala, Giovanni; Majello, Barbara; Azmoun, Somaiyeh; Tempest, Helen G; Premi, ... | R01ES030557 | Cell Mol Life Sci (2021 Nov) |
34463773
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2021 |
| How DNA damage and non-canonical nucleotides alter the telomerase catalytic cycle. | Sanford, Samantha L; Welfer, Griffin A; Freudenthal, Bret D; Opresko, Patricia L | R35ES030396 | DNA Repair (Amst) (2021 Nov) |
34371388
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2021 |
| Impact of DNA sequences on DNA 'opening' by the Rad4/XPC nucleotide excision repair complex. | Paul, Debamita; Mu, Hong; Tavakoli, Amirrasoul; Dai, Qing; Chakraborty, Sagnik; He, Chuan; Ans ... | R01ES025987 | DNA Repair (Amst) (2021 Nov) |
34428697
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2021 |
| Impact of structural ageism on greater violence against older persons: a cross-national study of 56 ... | Chang, E-Shien; Monin, Joan K; Zelterman, Daniel; Levy, Becca R | R01ES005775 | BMJ Open (2021 May 13) |
33986041
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2021 |
| Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic S ... | Varela, Jacqueline Gamboa; Pierce, Luke E; Guo, Xu; Price, Nathan E; Johnson, Kevin M; Yang, Z ... | R01ES021007, T32ES018827 | Chem Res Toxicol (2021 Apr 19) |
33784065
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2021 |
| Is high resolution a strict requirement for mass spectrometry-based cellular DNA adductomics? | Chang, Yuan-Jhe; Cooke, Marcus S; Chen, Yet-Ran; Yang, Shun-Fa; Li, Pei-Shan; Hu, Chiung-Wen; ... | R01ES030557 | Chemosphere (2021 Jul) |
33979922
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2021 |
| Light-induced modulation of DNA recognition by the Rad4/XPC damage sensor protein. | Tavakoli, Amirrasoul; Paul, Debamita; Mu, Hong; Kuchlyan, Jagannath; Baral, Saroj; Ansari, Anj ... | R01ES025987 | RSC Chem Biol (2021 Apr 01) |
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2021 |
| Long-term survival of an ovarian cancer patient harboring a RAD51C missense mutation. | Sullivan, Meghan R; Prakash, Rohit; Rawal, Yashpal; Wang, Weibin; Sung, Patrick; Radke, Marc R ... | R01ES007061, R01ES030335, R01ES031796 | Cold Spring Harb Mol Case Stud (2021 Apr) |
33832919
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2021 |
| Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability i ... | Jackson, Lindsey M; Dhoonmoon, Ashna; Hale, Anastasia; Dennis, Kady A; Schleicher, Emily M; Nic ... | R01ES026184 | Nucleic Acids Res (2021 Dec 16) |
34871431
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2021 |
| m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells. | Huff, Sarah; Tiwari, Shashi Kant; Gonzalez, Gwendolyn M; Wang, Yinsheng; Rana, Tariq M | R35ES031707, T32ES018827 | ACS Chem Biol (2021 02 19) |
33412003
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2021 |
| Mitochondrial Transcription Factor A Binds to and Promotes Mutagenic Transcriptional Bypass of O4-Al ... | He, Xiaomei; Wang, Pengcheng; Wang, Yinsheng | R35ES031707 | Anal Chem (2021 Jan 19) |
33290046
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2021 |
| Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote ... | Fu, Iwen; Geacintov, Nicholas E; Broyde, Suse | R01ES025987 | DNA Repair (Amst) (2021 Nov) |
34399316
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2021 |
| Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian c ... | Kit Leng Lui, Sarah; Keegan, Sarah; Tonzi, Peter; Kahli, Malik; Chen, Yu-Hung; Chalhoub, Noor; ... | R01ES031658 | Nat Protoc (2021 02) |
33442052
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2021 |
| MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling p ... | Luzwick, Jessica W; Dombi, Eszter; Boisvert, Rebecca A; Roy, Sunetra; Park, Soyoung; Kunnimalai ... | R01ES029680 | Sci Adv (2021 Dec 17) |
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2021 |
| Mutperiod: Analysis of periodic mutation rates in nucleosomes. | Morledge-Hampton, Benjamin; Wyrick, John J | R01ES028698, R01ES032814 | Comput Struct Biotechnol J (2021) |
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2021 |
| NAD+ bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint a ... | Li, Jianfeng; M Saville, Kate; Ibrahim, Md; Zeng, Xuemei; McClellan, Steve; Angajala, Anusha; ... | U01ES029518, U01ES029518 | NAR Cancer (2021 Dec) |
34806016
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2021 |
| NAD+ metabolism controls growth inhibition by HIF1 in normoxia and determines differential sensitivi ... | Luczak, Michal W; Krawic, Casey; Zhitkovich, Anatoly | R01ES028072, R01ES031002, R01ES031979 | Cell Cycle (2021 09) |
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2021 |
| Noninvasive Assessment of Epidermal Genomic Markers of UV Exposure in Skin. | Muradova, Elnara; Patel, Nishit; Sell, Brittney; Bittencourt, Bruna B; Ojeda, Sandra S; Adelman ... | R01ES030562 | J Invest Dermatol (2021 01) |
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2021 |
| PARP14 regulates cyclin D1 expression to promote cell-cycle progression. | O'Connor, Michael J; Thakar, Tanay; Nicolae, Claudia M; Moldovan, George-Lucian | R01ES026184 | Oncogene (2021 Jul) |
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2021 |
| PARP1: Structural insights and pharmacological targets for inhibition. | Spiegel, Jacob O; Van Houten, Bennett; Durrant, Jacob D | R35ES031638 | DNA Repair (Amst) (2021 Jul) |
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2021 |
| Post-transcriptional diversity in riboproteins and RNAs in aging and cancer. | Cruz, Jurandir; Lemos, Bernardo | R01ES027981 | Semin Cancer Biol (2021 11) |
34474152
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2021 |
| Primary saturation of α, β-unsaturated carbonyl containing fatty acids does not abolish electrophili ... | Snyder, Nathaniel W; O'Brien, James; Singh, Bhupinder; Buchan, Gregory; Arroyo, Alejandro D; Li ... | P01ES028949, P30ES013508, R44ES032522, U01ES029518, U01ES029518 | Chem Biol Interact (2021 Dec 01) |
34634267
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2021 |
| Proteome-Wide Profiling of Cellular Targets Modified by Dopamine Metabolites Using a Bio-Orthogonall ... | Hurben, Alexander K; Erber, Luke N; Tretyakova, Natalia Y; Doran, Todd M | R01ES023350, R01ES029911 | ACS Chem Biol (2021 Nov 19) |
34726906
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2021 |
| Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genom ... | Geijer, Marit E; Zhou, Di; Selvam, Kathiresan; Steurer, Barbara; Mukherjee, Chirantani; Evers, ... | R01ES028698 | Nat Cell Biol (2021 Jul) |
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2021 |
| RAD51 paralog function in replicative DNA damage and tolerance. | Rein, Hayley L; Bernstein, Kara A; Baldock, Robert A | R01ES030335, R01ES031796 | Curr Opin Genet Dev (2021 Dec) |
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2021 |
| Regulation of the Cell-Intrinsic DNA Damage Response by the Innate Immune Machinery. | Hayman, Thomas J; Glazer, Peter M | R01ES005775 | Int J Mol Sci (2021 Nov 25) |
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2021 |
| Role and Regulation of the RECQL4 Family during Genomic Integrity Maintenance. | Luong, Thong T; Bernstein, Kara A | R01ES030335 | Genes (Basel) (2021 Nov 29) |
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2021 |
| Searching for DNA Damage: Insights From Single Molecule Analysis. | Schaich, Matthew A; Van Houten, Bennett | R35ES031638 | Front Mol Biosci (2021) |
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2021 |
| Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover. | Jang, Sunbok; Schaich, Matthew A; Khuu, Cindy; Schnable, Brittani L; Majumdar, Chandrima; Watki ... | R35ES031638, T32ES007059 | Nucleic Acids Res (2021 Aug 20) |
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2021 |
| Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinder ... | Lee, Wei Ting C; Yin, Yandong; Morten, Michael J; Tonzi, Peter; Gwo, Pam Pam; Odermatt, Diana ... | R01ES031658 | Nat Commun (2021 05 05) |
33953191
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2021 |
| Site-Specific 5-Formyl Cytosine Mediated DNA-Histone Cross-Links: Synthesis and Polymerase Bypass by ... | Pujari, Suresh S; Wu, Mingxuan; Thomforde, Jenna; Wang, Zhipeng A; Chao, Christopher; Olson, N ... | R01ES023350 | Angew Chem Int Ed Engl (2021 Dec 13) |
34634172
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2021 |
| Super hotspots and super coldspots in the repair of UV-induced DNA damage in the human genome. | Jiang, Yuchao; Li, Wentao; Lindsey-Boltz, Laura A; Yang, Yuchen; Li, Yun; Sancar, Aziz | R00ES030015 | J Biol Chem (2021) |
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2021 |
| Synthesis and polymerase bypass studies of DNA-peptide and DNA-protein conjugates. | Pujari, Suresh S; Tretyakova, Natalia | R01ES023350 | Methods Enzymol (2021) |
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2021 |
| Synthesis of DNA Duplexes Containing Site-Specific Interstrand Cross-Links via Sequential Reductive ... | Housh, Kurt; Gates, Kent S | R01ES021007 | Chem Res Toxicol (2021 Nov 15) |
34694787
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2021 |
| Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly a ... | Koczor, Christopher A; Saville, Kate M; Andrews, Joel F; Clark, Jennifer; Fang, Qingming; Li, ... | P01ES028949, U01ES029518, U01ES029518 | Cell Rep (2021 11 02) |
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2021 |
| The emerging determinants of replication fork stability. | Thakar, Tanay; Moldovan, George-Lucian | R01ES026184 | Nucleic Acids Res (2021 Jul 21) |
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2021 |
| The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replis ... | Kumar, Charanya; Batra, Sahil; Griffith, Jack D; Remus, Dirk | R01ES031635 | Elife (2021 09 08) |
34494544
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2021 |
| The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replicati ... | Jiang, Min; Xie, Xie; Zhu, Xuefeng; Jiang, Shan; Milenkovic, Dusanka; Misic, Jelena; Shi, Yon ... | R01ES031635 | Sci Adv (2021 Jul) |
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2021 |
| The Multiple Cellular Roles of SMUG1 in Genome Maintenance and Cancer. | Raja, Sripriya; Van Houten, Bennett | R35ES031638 | Int J Mol Sci (2021 Feb 17) |
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2021 |
| The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination. | Roy, Upasana; Kwon, Youngho; Marie, Lea; Symington, Lorraine; Sung, Patrick; Lisby, Michael; G ... | R01ES007061 | Mol Cell (2021 03 04) |
33421364
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2021 |
| The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions. | Bonilla, Braulio; Brown, Alexander J; Hengel, Sarah R; Rapchak, Kyle S; Mitchell, Debra; Pressi ... | R01ES030335 | Elife (2021 11 01) |
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2021 |
| The SOS Error-Prone DNA Polymerase V Mutasome and β-Sliding Clamp Acting in Concert on Undamaged DNA ... | Sikand, Adhirath; Jaszczur, Malgorzata; Bloom, Linda B; Woodgate, Roger; Cox, Michael M; Goodma ... | R35ES028343 | Cells (2021 05 01) |
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2021 |
| Translesion Synthesis Past 5-Formylcytosine-Mediated DNA-Peptide Cross-Links by hPolη Is Dependent o ... | Thomforde, Jenna; Fu, Iwen; Rodriguez, Freddys; Pujari, Suresh S; Broyde, Suse; Tretyakova, Na ... | R01ES023350, R01ES025987 | Biochemistry (2021 06 15) |
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2021 |
| TRF2 promotes dynamic and stepwise looping of POT1 bound telomeric overhang. | Paul, Tapas; Liou, Wilson; Cai, Xinyi; Opresko, Patricia L; Myong, Sua | R35ES030396 | Nucleic Acids Res (2021 Dec 02) |
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2021 |
| Unified exact design with early stopping rules for single arm clinical trials with multiple endpoint ... | Wei, Wei; Esserman, Denise; Kane, Michael; Zelterman, Daniel | R01ES005775 | Stat Methods Med Res (2021 Jul) |
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2021 |
| Vulnerability of IDH1-Mutant Cancers to Histone Deacetylase Inhibition via Orthogonal Suppression of ... | Dow, Jonathan; Krysztofiak, Adam; Liu, Yanfeng; Colon-Rios, Daniel A; Rogers, Faye A; Glazer, ... | R01ES005775 | Mol Cancer Res (2021 12) |
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2021 |
| WEE1i-ATRi combination therapy: a promising low-dose treatment for CCNE1-amplified gynecologic cance ... | Goehring, Liana; Huang, Tony T | R01ES031658 | Cell Rep Med (2021 Sep 21) |
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2021 |
| WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells. | Datta, Arindam; Biswas, Kajal; Sommers, Joshua A; Thompson, Haley; Awate, Sanket; Nicolae, Cla ... | R01ES026184 | Nat Commun (2021 Nov 12) |
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2021 |
| YY1 interacts with guanine quadruplexes to regulate DNA looping and gene expression. | Li, Lin; Williams, Preston; Ren, Wendan; Wang, Michelle Y; Gao, Zi; Miao, Weili; Huang, Ming; ... | R35ES031707, T32ES018827 | Nat Chem Biol (2021 Feb) |
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2021 |
| A special issue dedicated to Dr. Bruce N. Ames: Introduction. | Walker, Graham C | R35ES028303 | Mutat Res Genet Toxicol Environ Mutagen (2020 Jan) |
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| A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis. | Chatterjee, Nimrat; D'Souza, Sanjay; Shabab, Mohammad; Harris, Cynthia A; Hilinski, Gerard J; V ... | R35ES028303 | Environ Mol Mutagen (2020 10) |
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2020 |
| Analysis of Telomere Length and Aberrations by Quantitative FISH. | Fouquerel, Elise; Opresko, Patricia | R35ES030396 | Methods Mol Biol (2020) |
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| Arsenic Exposure and Compromised Protein Quality Control. | Tam, Lok Ming; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2020 Jul 20) |
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| Arsenite Binds to ZNF598 to Perturb Ribosome-Associated Protein Quality Control. | Tam, Lok Ming; Jiang, Ji; Wang, Pengcheng; Wang, Yinsheng | R35ES031707 | Chem Res Toxicol (2020 Jul 20) |
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| Asymmetric repair of UV damage in nucleosomes imposes a DNA strand polarity on somatic mutations in ... | Mao, Peng; Smerdon, Michael J; Roberts, Steven A; Wyrick, John J | R01ES028698 | Genome Res (2020 01) |
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2020 |
| Atypical UV Photoproducts Induce Non-canonical Mutation Classes Associated with Driver Mutations in ... | Laughery, Marian F; Brown, Alexander J; Bohm, Kaitlynne A; Sivapragasam, Smitha; Morris, Haley ... | R01ES028698 | Cell Rep (2020 11 17) |
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2020 |
| Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenes ... | Galati, Melissa A; Hodel, Karl P; Gams, Miki S; Sudhaman, Sumedha; Bridge, Taylor; Zahurancik, ... | R01ES028271 | Cancer Res (2020 Dec 15) |
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2020 |
| Characterization of Cerebellum-Specific Ribosomal DNA Epigenetic Modifications in Alzheimer's Diseas ... | Faria, Tathyane C; Maldonado, Héctor L; Santos, Leonardo C; DeLabio, Roger; Payao, Spencer L M; ... | R01ES027981 | Mol Neurobiol (2020 Jun) |
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2020 |
| Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop ' ... | Williams, Jonathan D; Houserova, Dominika; Johnson, Bradley R; Dyniewski, Brad; Berroyer, Alexa ... | R01ES030084 | Nucleic Acids Res (2020 Jun 19) |
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2020 |
| Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal M ... | Msaouel, Pavlos; Malouf, Gabriel G; Su, Xiaoping; Yao, Hui; Tripathi, Durga N; Soeung, Melinda ... | R01ES029680 | Cancer Cell (2020 05 11) |
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| Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo D ... | Gao, Linfeng; Emperle, Max; Guo, Yiran; Grimm, Sara A; Ren, Wendan; Adam, Sabrina; Uryu, Hide ... | R35ES031707 | Nat Commun (2020 Jul 03) |
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2020 |
| Cross-linking of the DNA repair protein O6-alkylguanine DNA alkyltransferase to DNA in the presence ... | Ming, Xun; Michaelson-Richie, Erin D; Groehler 4th, Arnold S; Villalta, Peter W; Campbell, Coli ... | R01ES023350 | DNA Repair (Amst) (2020 05) |
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| Defective postreplication repair of UV photoproducts in melanoma: a mutator phenotype. | Brash, Douglas E; Seidman, Michael M | R01ES030562 | Mol Oncol (2020 01) |
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| Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity. | Zhu, Ru-Yi; Majumdar, Chandrima; Khuu, Cindy; De Rosa, Mariarosaria; Opresko, Patricia L; David ... | R35ES030396, T32ES007059 | ACS Cent Sci (2020 Oct 28) |
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| DNA polymerase δ proofreads errors made by DNA polymerase ε. | Bulock, Chelsea R; Xing, Xuanxuan; Shcherbakova, Polina V | R01ES015869 | Proc Natl Acad Sci U S A (2020 03 17) |
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| Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the ... | Schleicher, Emily M; Dhoonmoon, Ashna; Jackson, Lindsey M; Clements, Kristen E; Stump, Coryn L; ... | R01ES026184 | PLoS Genet (2020 11) |
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| Dynamic action of DNA repair proteins as revealed by single molecule techniques: Seeing is believing ... | Kong, Muwen; Beckwitt, Emily C; Van Houten, Bennett | R35ES031638 | DNA Repair (Amst) (2020 09) |
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| Expanding molecular roles of UV-DDB: Shining light on genome stability and cancer. | Beecher, Maria; Kumar, Namrata; Jang, Sunbok; Rapić-Otrin, Vesna; Van Houten, Bennett | R35ES031638 | DNA Repair (Amst) (2020 10) |
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| Exposure to microplastics cause gut damage, locomotor dysfunction, epigenetic silencing, and aggrava ... | Zhang, Yan; Wolosker, Marina B; Zhao, Yanping; Ren, Hongqiang; Lemos, Bernardo | R01ES027981 | Sci Total Environ (2020 Nov 20) |
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| Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity. | Wilk, Anna; Hayat, Faisal; Cunningham, Richard; Li, Jianfeng; Garavaglia, Silvia; Zamani, Leil ... | U01ES029518, U01ES029518 | Sci Rep (2020 01 20) |
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| FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cro ... | Awate, Sanket; Sommers, Joshua A; Datta, Arindam; Nayak, Sumeet; Bellani, Marina A; Yang, Oliv ... | R01ES026184 | Nucleic Acids Res (2020 09 18) |
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| Structural consequence of the most frequently recurring cancer-associated substitution in DNA polyme ... | Parkash, Vimal; Kulkarni, Yashraj; Ter Beek, Josy; Shcherbakova, Polina V; Kamerlin, Shina Caro ... | R01ES015869 | Nat Commun (2019 01 22) |
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2019 |
| Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucl ... | Paul, Debamita; Mu, Hong; Zhao, Hong; Ouerfelli, Ouathek; Jeffrey, Philip D; Broyde, Suse; Min ... | R01ES025987 | Nucleic Acids Res (2019 07 09) |
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| Synthetic lethality of a cell-penetrating anti-RAD51 antibody in PTEN-deficient melanoma and glioma ... | Turchick, Audrey; Liu, Yanfeng; Zhao, Weixi; Cohen, Inessa; Glazer, Peter M | R01ES005775 | Oncotarget (2019 Feb 12) |
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2019 |
| Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. | Fouquerel, Elise; Barnes, Ryan P; Uttam, Shikhar; Watkins, Simon C; Bruchez, Marcel P; Opresko, ... | R35ES030396 | Mol Cell (2019 Jul 11) |
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| Targeting phosphatases in cancer: suppression of many versus the ablation of one. | D'Arcy, Brandon M; Prakash, Aishwarya; Honkanen, Richard E | R01ES030084 | Oncotarget (2019 Nov 12) |
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2019 |
| The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination. | Zhao, Weixing; Wiese, Claudia; Kwon, Youngho; Hromas, Robert; Sung, Patrick | R01ES007061 | Annu Rev Biochem (2019 06 20) |
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| The impact of oxidative DNA damage and stress on telomere homeostasis. | Barnes, Ryan P; Fouquerel, Elise; Opresko, Patricia L | R35ES030396 | Mech Ageing Dev (2019 Jan) |
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| The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway. | Rosenbaum, Joel C; Bonilla, Braulio; Hengel, Sarah R; Mertz, Tony M; Herken, Benjamin W; Kazemi ... | R01ES007061 | Nat Commun (2019 08 05) |
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2019 |
| The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments. | Crickard, J Brooks; Xue, Chaoyou; Wang, Weibin; Kwon, Youngho; Sung, Patrick; Greene, Eric C | R01ES007061 | Nucleic Acids Res (2019 May 21) |
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2019 |
| Transcriptional Bypass of DNA-Protein and DNA-Peptide Conjugates by T7 RNA Polymerase. | Ji, Shaofei; Thomforde, Jenna; Rogers, Colette; Fu, Iwen; Broyde, Suse; Tretyakova, Natalia Y | R01ES023350, R01ES025987 | ACS Chem Biol (2019 12 20) |
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2019 |
| Virtual Pharmacophore Screening Identifies Small-Molecule Inhibitors of the Rev1-CT/RIR Protein-Prot ... | Dash, Radha C; Ozen, Zuleyha; McCarthy, Kaitlyn R; Chatterjee, Nimrat; Harris, Cynthia A; Rizzo ... | R35ES028303 | ChemMedChem (2019 09 04) |
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2019 |
| Vitamin C increases DNA breaks and suppresses DNA damage-independent activation of ATM by bleomycin. | Rubis, Blazej; Luczak, Michal W; Krawic, Casey; Zhitkovich, Anatoly | R01ES028072 | Free Radic Biol Med (2019 May 20) |
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2019 |
| 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in huma ... | Ji, Shaofei; Fu, Iwen; Naldiga, Spandana; Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... | R01ES023350, R01ES025987 | Nucleic Acids Res (2018 07 27) |
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2018 |
| A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) o ... | Wang, Weibin; Daley, James M; Kwon, Youngho; Xue, Xiaoyu; Krasner, Danielle S; Miller, Adam S; ... | R01ES007061 | J Biol Chem (2018 11 02) |
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2018 |
| A quantitative PCR-based assay reveals that nucleotide excision repair plays a predominant role in t ... | Chesner, Lisa N; Campbell, Colin | R01ES023350 | DNA Repair (Amst) (2018 Feb) |
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2018 |
| A Simple, Rapid, and Quantitative Assay to Measure Repair of DNA-protein Crosslinks on Plasmids Tran ... | Chesner, Lisa N; Campbell, Colin | R01ES023350 | J Vis Exp (2018 Mar 05) |
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2018 |
| Corrigendum: 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce muta ... | Ji, Shaofei; Fu, Iwen; Naldiga, Spandana; Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... | R01ES025987 | Nucleic Acids Res (2018 Oct 12) |
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| DNA Damage, Mutagenesis and Cancer. | Basu, Ashis K | R01ES023350 | Int J Mol Sci (2018 Mar 23) |
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2018 |
| Electron-Mediated Aminyl and Iminyl Radicals from C5 Azido-Modified Pyrimidine Nucleosides Augment R ... | Wen, Zhiwei; Peng, Jufang; Tuttle, Paloma R; Ren, Yaou; Garcia, Carol; Debnath, Dipra; Rishi, ... | R01ES005775 | Org Lett (2018 Dec 07) |
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2018 |
| Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributio ... | Chakraborty, Sagnik; Steinbach, Peter J; Paul, Debamita; Mu, Hong; Broyde, Suse; Min, Jung-Hyu ... | R01ES025987 | Nucleic Acids Res (2018 02 16) |
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2018 |
| Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice (Mus ... | Deng, Yongfeng; Zhang, Yan; Qiao, Ruxia; Bonilla, Melvin M; Yang, Xiaoliang; Ren, Hongqiang; L ... | R01ES027981 | J Hazard Mater (2018 Sep 05) |
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2018 |
| Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is dri ... | Hodel, Karl P; de Borja, Richard; Henninger, Erin E; Campbell, Brittany B; Ungerleider, Nathan; ... | R01ES028271 | Elife (2018 02 28) |
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2018 |
| Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae. | Barbari, Stephanie R; Kane, Daniel P; Moore, Elizabeth A; Shcherbakova, Polina V | R01ES015869 | G3 (Bethesda) (2018 Mar 02) |
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2018 |
| Histone tails decrease N7-methyl-2'-deoxyguanosine depurination and yield DNA-protein cross-links in ... | Yang, Kun; Park, Daeyoon; Tretyakova, Natalia Y; Greenberg, Marc M | R01ES023350 | Proc Natl Acad Sci U S A (2018 11 27) |
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2018 |
| Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and ... | Lu, Yuhong; Liu, Yanfeng; Oeck, Sebastian; Glazer, Peter M | R01ES005775 | Mol Cancer Res (2018 10) |
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2018 |
| Importance of homo-dimerization of Fanconi-associated nuclease 1 in DNA flap cleavage. | Rao, Timsi; Longerich, Simonne; Zhao, Weixing; Aihara, Hideki; Sung, Patrick; Xiong, Yong | R01ES007061 | DNA Repair (Amst) (2018 04) |
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2018 |
| Incomplete base excision repair contributes to cell death from antibiotics and other stresses. | Gruber, Charley C; Walker, Graham C | R35ES028303 | DNA Repair (Amst) (2018 Nov) |
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| Introduction to the Thematic Minireview Series: DNA double-strand break repair and pathway choice. | Sung, Patrick | R01ES007061 | J Biol Chem (2018 07 06) |
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| Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination ... | Sulkowski, Parker L; Sundaram, Ranjini K; Oeck, Sebastian; Corso, Christopher D; Liu, Yanfeng; ... | R01ES005775 | Nat Genet (2018 Aug) |
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2018 |
| Lesion Sensing during Initial Binding by Yeast XPC/Rad4: Toward Predicting Resistance to Nucleotide ... | Mu, Hong; Zhang, Yingkai; Geacintov, Nicholas E; Broyde, Suse | R01ES025987 | Chem Res Toxicol (2018 11 19) |
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2018 |
| Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient c ... | Clements, Kristen E; Thakar, Tanay; Nicolae, Claudia M; Liang, Xinwen; Wang, Hong-Gang; Moldova ... | R01ES026184 | Nucleic Acids Res (2018 Sep 28) |
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2018 |
| Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase. | Crickard, J Brooks; Kaniecki, Kyle; Kwon, Youngho; Sung, Patrick; Greene, Eric C | R01ES007061 | Proc Natl Acad Sci U S A (2018 Oct 23) |
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2018 |
| Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excisi ... | Mu, Hong; Geacintov, Nicholas E; Broyde, Suse; Yeo, Jung-Eun; Schärer, Orlando D | R01ES025987 | DNA Repair (Amst) (2018 11) |
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2018 |
| Monoubiquitinated γ-H2AX: Abundant product and specific biomarker for non-apoptotic DNA double-stran ... | Luczak, Michal W; Zhitkovich, Anatoly | R01ES028072 | Toxicol Appl Pharmacol (2018 Sep 15) |
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2018 |
| Nucleosome positions establish an extended mutation signature in melanoma. | Brown, Alexander J; Mao, Peng; Smerdon, Michael J; Wyrick, John J; Roberts, Steven A | R01ES028698 | PLoS Genet (2018 11) |
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2018 |
| Oxidative cross-linking of proteins to DNA following ischemia-reperfusion injury. | Groehler 4th, Arnold; Kren, Stefan; Li, Qinglu; Robledo-Villafane, Maggie; Schmidt, Joshua; Gar ... | R01ES023350 | Free Radic Biol Med (2018 May 20) |
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2018 |
| PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress. | Schleicher, Emily M; Galvan, Adri M; Imamura-Kawasawa, Yuka; Moldovan, George-Lucian; Nicolae, ... | R01ES026184 | Nucleic Acids Res (2018 09 28) |
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2018 |
| PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF. | Sulkowski, Parker L; Scanlon, Susan E; Oeck, Sebastian; Glazer, Peter M | R01ES005775 | Mol Cancer Res (2018 08) |
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2018 |
| Regulation of Hed1 and Rad54 binding during maturation of the meiosis-specific presynaptic complex. | Crickard, J Brooks; Kaniecki, Kyle; Kwon, YoungHo; Sung, Patrick; Lisby, Michael; Greene, Eric ... | R01ES007061 | EMBO J (2018 Apr 03) |
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2018 |
| Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis comp ... | Rizzo, Alessandro A; Vassel, Faye-Marie; Chatterjee, Nimrat; D'Souza, Sanjay; Li, Yunfeng; Hao, ... | R35ES028303 | Proc Natl Acad Sci U S A (2018 Aug 28) |
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2018 |
| Site-specific cross-linking of proteins to DNA via a new bioorthogonal approach employing oxime liga ... | Pujari, Suresh S; Zhang, Yi; Ji, Shaofei; Distefano, Mark D; Tretyakova, Natalia Y | R01ES023350 | Chem Commun (Camb) (2018 Jun 14) |
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2018 |
| Smoking gun for a rare mutation mechanism. | Goodman, Myron F | R35ES028343 | Nature (2018 Feb 08) |
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| Spontaneous self-segregation of Rad51 and Dmc1 DNA recombinases within mixed recombinase filaments. | Crickard, J Brooks; Kaniecki, Kyle; Kwon, YoungHo; Sung, Patrick; Greene, Eric C | R01ES007061 | J Biol Chem (2018 03 16) |
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2018 |
| Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity ... | Scanlon, Susan E; Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M | R01ES005775 | Oncotarget (2018 Jan 12) |
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2018 |
| Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing D ... | Cai, Yuqin; Fu, Iwen; Geacintov, Nicholas E; Zhang, Yingkai; Broyde, Suse | R01ES025987 | DNA Repair (Amst) (2018 May) |
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2018 |
| The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells. | Kim, Hoon; Lin, Qun; Glazer, Peter M; Yun, Zhong | R01ES005775 | Breast Cancer Res (2018 03 06) |
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2018 |
| The long-range interaction map of ribosomal DNA arrays. | Yu, Shoukai; Lemos, Bernardo | R01ES027981 | PLoS Genet (2018 03) |
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| Toxicological Antagonism among Welding Fume Metals: Inactivation of Soluble Cr(VI) by Iron. | Krawic, Casey; Zhitkovich, Anatoly | R01ES028072 | Chem Res Toxicol (2018 Nov 19) |
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| Urinary DNA adductomics - A novel approach for exposomics. | Cooke, Marcus S; Hu, Chiung-Wen; Chang, Yuan-Jhe; Chao, Mu-Rong | R01ES030557 | Environ Int (2018 Dec) |
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| What is the potential of nanolock- and nanocross-nanopore technology in cancer diagnosis? | Gu, Li-Qun; Gates, Kent S; Wang, Michael X; Li, Guangfu | R01ES021007 | Expert Rev Mol Diagn (2018 Feb) |
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2018 |
| 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and indu ... | Sulkowski, Parker L; Corso, Christopher D; Robinson, Nathaniel D; Scanlon, Susan E; Purshouse, ... | R01ES005775 | Sci Transl Med (2017 02 01) |
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2017 |
| A novel role of the Dna2 translocase function in DNA break resection. | Miller, Adam S; Daley, James M; Pham, Nhung Tuyet; Niu, Hengyao; Xue, Xiaoyu; Ira, Grzegorz; S ... | R01ES007061 | Genes Dev (2017 Mar 01) |
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| A parametric model to estimate the proportion from true null using a distribution for p-values. | Yu, Chang; Zelterman, Daniel | R01ES005775 | Comput Stat Data Anal (2017 Oct) |
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| A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA ... | Yang, Zhiyu; Nejad, Maryam Imani; Varela, Jacqueline Gamboa; Price, Nathan E; Wang, Yinsheng; G ... | R01ES021007, T32ES018827 | DNA Repair (Amst) (2017 Apr) |
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2017 |
| Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy. | Gupta, Anisha; Quijano, Elias; Liu, Yanfeng; Bahal, Raman; Scanlon, Susan E; Song, Eric; Hsieh ... | R01ES005775 | Mol Ther Nucleic Acids (2017 Dec 15) |
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| BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing. | Zhao, Weixing; Steinfeld, Justin B; Liang, Fengshan; Chen, Xiaoyong; Maranon, David G; Jian Ma, ... | R01ES007061 | Nature (2017 Oct 19) |
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2017 |
| Cellular Repair of DNA-DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane. | Chesner, Lisa N; Degner, Amanda; Sangaraju, Dewakar; Yomtoubian, Shira; Wickramaratne, Susith; ... | R01ES023350 | Int J Mol Sci (2017 May 18) |
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| Chemical Biology of N5-Substituted Formamidopyrimidine DNA Adducts. | Pujari, Suresh S; Tretyakova, Natalia | R01ES023350 | Chem Res Toxicol (2017 Jan 17) |
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| Comprehensive Analysis of Hypermutation in Human Cancer. | Campbell, Brittany B; Light, Nicholas; Fabrizio, David; Zatzman, Matthew; Fuligni, Fabio; de Bo ... | R01ES028271 | Cell (2017 Nov 16) |
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2017 |
| Controlling the Graphene-Bio Interface: Dispersions in Animal Sera for Enhanced Stability and Reduce ... | Pattammattel, Ajith; Pande, Paritosh; Kuttappan, Deepa; Puglia, Megan; Basu, Ashis K; Amalaradj ... | R01ES023350 | Langmuir (2017 Dec 12) |
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| Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange. | Xu, Jingfei; Zhao, Lingyun; Xu, Yuanyuan; Zhao, Weixing; Sung, Patrick; Wang, Hong-Wei | R01ES007061 | Nat Struct Mol Biol (2017 Jan) |
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| Dissociation of Rad51 Presynaptic Complexes and Heteroduplex DNA Joints by Tandem Assemblies of Srs2 ... | Kaniecki, Kyle; De Tullio, Luisina; Gibb, Bryan; Kwon, Youngho; Sung, Patrick; Greene, Eric C | R01ES007061 | Cell Rep (2017 Dec 12) |
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2017 |
| Enhancement of BLM-DNA2-Mediated Long-Range DNA End Resection by CtIP. | Daley, James M; Jimenez-Sainz, Judit; Wang, Weibin; Miller, Adam S; Xue, Xiaoyu; Nguyen, Kevin ... | R01ES007061 | Cell Rep (2017 Oct 10) |
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| Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork. | Choe, Katherine N; Moldovan, George-Lucian | R01ES026184 | Mol Cell (2017 Feb 02) |
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| Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex. | Ma, Chu Jian; Kwon, Youngho; Sung, Patrick; Greene, Eric C | R01ES007061 | J Biol Chem (2017 07 14) |
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2017 |
| Mass Spectrometry Based Proteomics Study of Cisplatin-Induced DNA-Protein Cross-Linking in Human Fib ... | Ming, Xun; Groehler 4th, Arnold; Michaelson-Richie, Erin D; Villalta, Peter W; Campbell, Colin; ... | R01ES023350 | Chem Res Toxicol (2017 Apr 17) |
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| Mass Spectrometry-Based Tools to Characterize DNA-Protein Cross-Linking by Bis-Electrophiles. | Groehler 4th, Arnold; Degner, Amanda; Tretyakova, Natalia Y | R01ES023350 | Basic Clin Pharmacol Toxicol (2017 Sep) |
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| Mutagenicity of a Model DNA-Peptide Cross-Link in Human Cells: Roles of Translesion Synthesis DNA Po ... | Pande, Paritosh; Ji, Shaofei; Mukherjee, Shivam; Schärer, Orlando D; Tretyakova, Natalia Y; Bas ... | R01ES023350 | Chem Res Toxicol (2017 Feb 20) |
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| Nanoarmoring: strategies for preparation of multi-catalytic enzyme polymer conjugates and enhancemen ... | Zore, Omkar V; Pande, Paritosh; Okifo, Oghenenyerovwo; Basu, Ashis K; Kasi, Rajeswari M; Kumar, ... | R01ES023350 | RSC Adv (2017) |
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| Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorig ... | Scanlon, Susan E; Scanlon, Christine D; Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M | R01ES005775 | Carcinogenesis (2017 06 01) |
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| Nucleosome Histone Tail Conformation and Dynamics: Impacts of Lysine Acetylation and a Nearby Minor ... | Fu, Iwen; Cai, Yuqin; Geacintov, Nicholas E; Zhang, Yingkai; Broyde, Suse | R01ES025987 | Biochemistry (2017 Apr 11) |
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2017 |
| Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA D ... | Adkins, Nicholas L; Swygert, Sarah G; Kaur, Parminder; Niu, Hengyao; Grigoryev, Sergei A; Sung, ... | P30ES025128, R01ES007061 | J Biol Chem (2017 Mar 31) |
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2017 |
| Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a ... | Mu, Hong; Geacintov, Nicholas E; Min, Jung-Hyun; Zhang, Yingkai; Broyde, Suse | R01ES025987 | Chem Res Toxicol (2017 Jun 19) |
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2017 |
| Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polym ... | Mertz, T M; Baranovskiy, A G; Wang, J; Tahirov, T H; Shcherbakova, P V | R01ES015869 | Oncogene (2017 Aug) |
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| Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease ensemble in the processing of DNA-bound obstacles. | Wang, Weibin; Daley, James M; Kwon, Youngho; Krasner, Danielle S; Sung, Patrick | R01ES007061 | Genes Dev (2017 Dec 01) |
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| Repair-Resistant DNA Lesions. | Geacintov, Nicholas E; Broyde, Suse | R01ES025987 | Chem Res Toxicol (2017 Aug 21) |
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| Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for ... | Barbari, Stephanie R; Shcherbakova, Polina V | R01ES015869 | DNA Repair (Amst) (2017 Aug) |
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| Reversible DNA-Protein Cross-Linking at Epigenetic DNA Marks. | Ji, Shaofei; Shao, Hongzhao; Han, Qiyuan; Seiler, Christopher L; Tretyakova, Natalia Y | R01ES023350 | Angew Chem Int Ed Engl (2017 Nov 06) |
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| Ribosomal DNA copy number amplification and loss in human cancers is linked to tumor genetic context ... | Wang, Meng; Lemos, Bernardo | R01ES027981 | PLoS Genet (2017 Sep) |
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| Role of the Pif1-PCNA Complex in Pol δ-Dependent Strand Displacement DNA Synthesis and Break-Induced ... | Buzovetsky, Olga; Kwon, Youngho; Pham, Nhung Tuyet; Kim, Claire; Ira, Grzegorz; Sung, Patrick; ... | R01ES007061 | Cell Rep (2017 Nov 14) |
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| Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases. | Lee, Ja Yil; Steinfeld, Justin B; Qi, Zhi; Kwon, YoungHo; Sung, Patrick; Greene, Eric C | R01ES007061 | J Biol Chem (2017 06 30) |
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| Sequence-Specific Covalent Capture Coupled with High-Contrast Nanopore Detection of a Disease-Derive ... | Nejad, Maryam Imani; Shi, Ruicheng; Zhang, Xinyue; Gu, Li-Qun; Gates, Kent S | R01ES021007 | Chembiochem (2017 Jul 18) |
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| The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RN ... | Kolbanovskiy, Marina; Chowdhury, Moinuddin A; Nadkarni, Aditi; Broyde, Suse; Geacintov, Nichola ... | R01ES025987 | Biochemistry (2017 Jun 20) |
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| Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases. | Basu, Ashis K; Pande, Paritosh; Bose, Arindam | R01ES023350 | Chem Res Toxicol (2017 Jan 17) |
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| Ultrathin Graphene-Protein Supercapacitors for Miniaturized Bioelectronics. | Mosa, Islam M; Pattammattel, Ajith; Kadimisetty, Karteek; Pande, Paritosh; El-Kady, Maher F; Bi ... | R01ES023350 | Adv Energy Mater (2017 Sep 06) |
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| Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiol ... | Kochenova, Olga V; Bezalel-Buch, Rachel; Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... | R01ES015869 | Nucleic Acids Res (2017 02 17) |
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| Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous ... | De Tullio, Luisina; Kaniecki, Kyle; Kwon, Youngho; Crickard, J Brooks; Sung, Patrick; Greene, ... | R01ES007061 | Cell Rep (2017 Oct 17) |
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| Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Sy ... | Wickramaratne, Susith; Ji, Shaofei; Mukherjee, Shivam; Su, Yan; Pence, Matthew G; Lior-Hoffmann ... | R01ES023350, R01ES025987 | J Biol Chem (2016 Nov 04) |
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| Comparative Error-Free and Error-Prone Translesion Synthesis of N(2)-2'-Deoxyguanosine Adducts Forme ... | Bose, Arindam; Surugihalli, Chaitra; Pande, Paritosh; Champeil, Elise; Basu, Ashis K | R01ES023350 | Chem Res Toxicol (2016 May 16) |
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| Covalent DNA-Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells. | Groehler 4th, Arnold; Villalta, Peter W; Campbell, Colin; Tretyakova, Natalia | R01ES023350 | Chem Res Toxicol (2016 Feb 15) |
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| Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by ... | Xue, Xiaoyu; Papusha, Alma; Choi, Koyi; Bonner, Jacob N; Kumar, Sandeep; Niu, Hengyao; Kaur, ... | R01ES007061 | Genes Dev (2016 03 15) |
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| Effective molarity in a nucleic acid-controlled reaction. | Catalano, Michael J; Price, Nathan E; Gates, Kent S | R01ES021007 | Bioorg Med Chem Lett (2016 Jun 01) |
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| Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end ... | Chen, Xuefeng; Niu, Hengyao; Yu, Yang; Wang, Jingjing; Zhu, Shuangyi; Zhou, Jianjie; Papusha, ... | R01ES007061 | Nucleic Acids Res (2016 Apr 07) |
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| HUWE1 interacts with PCNA to alleviate replication stress. | Choe, Katherine N; Nicolae, Claudia M; Constantin, Daniel; Imamura Kawasawa, Yuka; Delgado-Diaz, ... | R01ES026184 | EMBO Rep (2016 06) |
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| Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1. | Callender, Tracy L; Laureau, Raphaelle; Wan, Lihong; Chen, Xiangyu; Sandhu, Rima; Laljee, Saif ... | R01ES007061 | PLoS Genet (2016 Aug) |
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| miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expre ... | Czochor, Jennifer R; Sulkowski, Parker; Glazer, Peter M | R01ES005775 | Mol Cancer Res (2016 Apr) |
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2016 |
| PARP10 deficiency manifests by severe developmental delay and DNA repair defect. | Shahrour, Maher Awni; Nicolae, Claudia M; Edvardson, Simon; Ashhab, Motee; Galvan, Adri M; Cons ... | R01ES026184 | Neurogenetics (2016 Oct) |
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2016 |
| Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex. | Liang, Fengshan; Longerich, Simonne; Miller, Adam S; Tang, Caroline; Buzovetsky, Olga; Xiong, ... | R01ES007061 | Cell Rep (2016 Jun 07) |
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2016 |
| Simple, High-Yield Syntheses of DNA Duplexes Containing Interstrand DNA-DNA Cross-Links Between an N ... | Gamboa Varela, Jacqueline; Gates, Kent S | R01ES021007 | Curr Protoc Nucleic Acid Chem (2016 Jun 01) |
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2016 |
| Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks. | Cassani, Corinne; Gobbini, Elisa; Wang, Weibin; Niu, Hengyao; Clerici, Michela; Sung, Patrick; ... | R01ES007061 | PLoS Biol (2016 Feb) |
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2016 |
| A simple, high-yield synthesis of DNA duplexes containing a covalent, thermally cleavable interstran ... | Gamboa Varela, Jacqueline; Gates, Kent S | R01ES021007 | Angew Chem Int Ed Engl (2015 Jun 22) |
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2015 |
| Characterization of Interstrand DNA-DNA Cross-Links Derived from Abasic Sites Using Bacteriophage ϕ2 ... | Yang, Zhiyu; Price, Nathan E; Johnson, Kevin M; Gates, Kent S | R01ES021007 | Biochemistry (2015 Jul 14) |
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2015 |
| Characterization of Interstrand DNA-DNA Cross-Links Using the α-Hemolysin Protein Nanopore. | Zhang, Xinyue; Price, Nathan E; Fang, Xi; Yang, Zhiyu; Gu, Li-Qun; Gates, Kent S | R01ES021007 | ACS Nano (2015 Dec 22) |
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2015 |
| Chemical and structural characterization of interstrand cross-links formed between abasic sites and ... | Price, Nathan E; Catalano, Michael J; Liu, Shuo; Wang, Yinsheng; Gates, Kent S | R01ES021007 | Nucleic Acids Res (2015 Apr 20) |
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2015 |
| Chemical structure and properties of interstrand cross-links formed by reaction of guanine residues ... | Catalano, Michael J; Liu, Shuo; Andersen, Nisana; Yang, Zhiyu; Johnson, Kevin M; Price, Nathan ... | R01ES021007 | J Am Chem Soc (2015 Mar 25) |
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2015 |
| Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing i ... | Mertz, Tony M; Sharma, Sushma; Chabes, Andrei; Shcherbakova, Polina V | R01ES015869 | Proc Natl Acad Sci U S A (2015 May 12) |
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2015 |
| DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone c ... | Kochenova, Olga V; Daee, Danielle L; Mertz, Tony M; Shcherbakova, Polina V | R01ES015869 | PLoS Genet (2015 Mar) |
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2015 |
| DNA sequence alignment by microhomology sampling during homologous recombination. | Qi, Zhi; Redding, Sy; Lee, Ja Yil; Gibb, Bryan; Kwon, YoungHo; Niu, Hengyao; Gaines, William ... | R01ES007061 | Cell (2015 Feb 26) |
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2015 |
| DNA-Protein Cross-Links: Formation, Structural Identities, and Biological Outcomes. | Tretyakova, Natalia Y; Groehler 4th, Arnold; Ji, Shaofei | R01ES023350 | Acc Chem Res (2015 Jun 16) |
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2015 |
| Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA ... | Wickramaratne, Susith; Boldry, Emily J; Buehler, Charles; Wang, Yen-Chih; Distefano, Mark D; Tr ... | R01ES023350 | J Biol Chem (2015 Jan 09) |
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2015 |
| Functions and regulation of the multitasking FANCM family of DNA motor proteins. | Xue, Xiaoyu; Sung, Patrick; Zhao, Xiaolan | R01ES007061 | Genes Dev (2015 Sep 01) |
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2015 |
| LKB1 preserves genome integrity by stimulating BRCA1 expression. | Gupta, Romi; Liu, Alex Y; Glazer, Peter M; Wajapeyee, Narendra | R01ES005775 | Nucleic Acids Res (2015 Jan) |
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2015 |
| Markov counting models for correlated binary responses. | Crawford, Forrest W; Zelterman, Daniel | R01ES005775 | Biostatistics (2015 Jul) |
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2015 |
| Mass spectrometry for the assessment of the occurrence and biological consequences of DNA adducts. | Liu, Shuo; Wang, Yinsheng | R01ES021007 | Chem Soc Rev (2015 Nov 07) |
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2015 |
| Mechanism of action studies of lomaiviticin A and the monomeric lomaiviticin aglycon. Selective and ... | Colis, Laureen C; Hegan, Denise C; Kaneko, Miho; Glazer, Peter M; Herzon, Seth B | R01ES005775 | J Am Chem Soc (2015 May 06) |
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2015 |
| MicroRNA silencing for cancer therapy targeted to the tumour microenvironment. | Cheng, Christopher J; Bahal, Raman; Babar, Imran A; Pincus, Zachary; Barrera, Francisco; Liu, ... | R01ES005775 | Nature (2015 Feb 05) |
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2015 |
| Mimicking Ribosomal Unfolding of RNA Pseudoknot in a Protein Channel. | Zhang, Xinyue; Xu, Xiaojun; Yang, Zhiyu; Burcke, Andrew J; Gates, Kent S; Chen, Shi-Jie; Gu, ... | R01ES021007 | J Am Chem Soc (2015 Dec 23) |
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2015 |
| Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment. | Scanlon, Susan E; Glazer, Peter M | R01ES005775 | DNA Repair (Amst) (2015 Aug) |
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2015 |
| Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry. | Zhao, Weixing; Vaithiyalingam, Sivaraja; San Filippo, Joseph; Maranon, David G; Jimenez-Sainz, ... | R01ES007061 | Mol Cell (2015 Jul 16) |
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2015 |
| Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Ra ... | Gaines, William A; Godin, Stephen K; Kabbinavar, Faiz F; Rao, Timsi; VanDemark, Andrew P; Sung, ... | R01ES007061 | Nat Commun (2015 Jul 28) |
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2015 |
| Selective modulation of the functions of a conserved DNA motor by a histone fold complex. | Xue, Xiaoyu; Choi, Koyi; Bonner, Jacob N; Szakal, Barnabas; Chen, Yu-Hung; Papusha, Alma; Saro ... | R01ES007061 | Genes Dev (2015 05 15) |
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2015 |
| Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homol ... | Zhao, Weixing; Sung, Patrick | R01ES007061 | Nucleic Acids Res (2015 Apr 30) |
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2015 |
| Synthesis of DNA Oligodeoxynucleotides Containing Site-Specific 1,3-Butadiene-Deoxyadenosine Lesions ... | Wickramaratne, Susith; Seiler, Christopher L; Tretyakova, Natalia Y | R01ES023350 | Curr Protoc Nucleic Acid Chem (2015 Jun 03) |
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2015 |
| Synthetic viability genomic screening defines Sae2 function in DNA repair. | Puddu, Fabio; Oelschlaegel, Tobias; Guerini, Ilaria; Geisler, Nicola J; Niu, Hengyao; Herzog, ... | R01ES007061 | EMBO J (2015 Jun 03) |
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| Tumor suppressor p53 stole the AKT in hypoxia. | Yun, Zhong; Glazer, Peter M | R01ES005775 | J Clin Invest (2015 Jun) |
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2015 |
| A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotyp ... | Kane, Daniel P; Shcherbakova, Polina V | R01ES015869 | Cancer Res (2014 Apr 1) |
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2014 |
| Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms. | Potenski, Catherine J; Niu, Hengyao; Sung, Patrick; Klein, Hannah L | R01ES007061 | Nature (2014 Jul 10) |
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2014 |
| Concentration-dependent exchange of replication protein A on single-stranded DNA revealed by single- ... | Gibb, Bryan; Ye, Ling F; Gergoudis, Stephanie C; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; G ... | R01ES007061 | PLoS One (2014) |
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2014 |
| Covalent adduct formation between the antihypertensive drug hydralazine and abasic sites in double- ... | Melton, Douglas; Lewis, Calvin D; Price, Nathan E; Gates, Kent S | R01ES021007 | Chem Res Toxicol (2014 Dec 15) |
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2014 |
| DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures. | Northam, Matthew R; Moore, Elizabeth A; Mertz, Tony M; Binz, Sara K; Stith, Carrie M; Stepchenk ... | R01ES015869 | Nucleic Acids Res (2014 Jan) |
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2014 |
| Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair ... | Liu, Yan; Gaines, William A; Callender, Tracy; Busygina, Valeria; Oke, Ashwini; Sung, Patrick; ... | R01ES007061 | PLoS Genet (2014 Jan) |
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2014 |
| Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins. | Scanlon, Susan E; Glazer, Peter M | R01ES005775 | Mol Cancer Res (2014 Jul) |
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2014 |
| Interstrand DNA-DNA cross-link formation between adenine residues and abasic sites in duplex DNA. | Price, Nathan E; Johnson, Kevin M; Wang, Jin; Fekry, Mostafa I; Wang, Yinsheng; Gates, Kent S | R01ES021007 | J Am Chem Soc (2014 Mar 5) |
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2014 |
| Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing. | Zhao, Weixing; Saro, Dorina; Hammel, Michal; Kwon, Youngho; Xu, Yuanyuan; Rambo, Robert P; Wil ... | R01ES007061 | Nucleic Acids Res (2014 Jan) |
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2014 |
| Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules. | Gibb, Bryan; Ye, Ling F; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; Greene, Eric C | R01ES007061 | Nat Struct Mol Biol (2014 Oct) |
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2014 |
| Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences. | Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K | R01ES023350 | PLoS One (2014) |
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| Restriction of replication fork regression activities by a conserved SMC complex. | Xue, Xiaoyu; Choi, Koyi; Bonner, Jacob N; Chiba, Tamara; Kwon, Youngho; Xu, Yuanyuan; Sanchez, ... | R01ES007061 | Mol Cell (2014 11 06) |
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2014 |
| Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on t ... | Lu, Yuhong; Wajapeyee, Narendra; Turker, Mitchell S; Glazer, Peter M | R01ES005775 | Cell Rep (2014 Jul 24) |
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2014 |
| The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA. | Colis, Laureen C; Woo, Christina M; Hegan, Denise C; Li, Zhenwu; Glazer, Peter M; Herzon, Seth ... | R01ES005775 | Nat Chem (2014 Jun) |
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| Toward hypoxia-selective DNA-alkylating agents built by grafting nitrogen mustards onto the bioreduc ... | Johnson, Kevin M; Parsons, Zachary D; Barnes, Charles L; Gates, Kent S | R01ES021007 | J Org Chem (2014 Aug 15) |
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| A quantitative mass spectrometry-based approach for assessing the repair of 8-methoxypsoralen-induce ... | Liu, Shuo; Wang, Yinsheng | R01ES021007 | Anal Chem (2013 Jul 16) |
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| A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in m ... | Kadyrova, Lyudmila Y; Mertz, Tony M; Zhang, Yu; Northam, Matthew R; Sheng, Ziwei; Lobachev, Ki ... | R01ES015869 | PLoS Genet (2013 Oct) |
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| Functional attributes of the Saccharomyces cerevisiae meiotic recombinase Dmc1. | Busygina, Valeria; Gaines, William A; Xu, Yuanyuan; Kwon, Youngho; Williams, Gareth J; Lin, Sh ... | R01ES007061 | DNA Repair (Amst) (2013 Sep) |
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| Hypoxia and DNA repair. | Glazer, Peter M; Hegan, Denise C; Lu, Yuhong; Czochor, Jennifer; Scanlon, Susan E | R01ES005775 | Yale J Biol Med (2013 Dec 13) |
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| Nucleosome dynamics regulates DNA processing. | Adkins, Nicholas L; Niu, Hengyao; Sung, Patrick; Peterson, Craig L | R01ES007061 | Nat Struct Mol Biol (2013 Jul) |
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| On the formation and properties of interstrand DNA-DNA cross-links forged by reaction of an abasic s ... | Johnson, Kevin M; Price, Nathan E; Wang, Jin; Fekry, Mostafa I; Dutta, Sanjay; Seiner, Derrick ... | R01ES021007 | J Am Chem Soc (2013 Jan 23) |
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| Pif1 helicase and Polýý promote recombination-coupled DNA synthesis via bubble migration. | Wilson, Marenda A; Kwon, YoungHo; Xu, Yuanyuan; Chung, Woo-Hyun; Chi, Peter; Niu, Hengyao; May ... | R01ES007061 | Nature (2013 Oct 17) |
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| RIF1 in DNA break repair pathway choice. | Daley, James M; Sung, Patrick | R01ES007061 | Mol Cell (2013 Mar 07) |
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| Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα- ... | Xue, Xiaoyu; Raynard, Steven; Busygina, Valeria; Singh, Akhilesh K; Sung, Patrick | R01ES007061 | J Biol Chem (2013 May 17) |
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| Roles of DNA helicases in the mediation and regulation of homologous recombination. | Daley, James M; Niu, Hengyao; Sung, Patrick | R01ES007061 | Adv Exp Med Biol (2013) |
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| Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair. | Dunlop, Myun Hwa; Dray, Eloïse; Zhao, Weixing; San Filippo, Joseph; Tsai, Miaw-Sheue; Leung, S ... | R01ES007061 | J Biol Chem (2012 Apr 06) |
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| Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiot ... | Busygina, Valeria; Saro, Dorina; Williams, Gareth; Leung, Wing-Kit; Say, Amanda F; Sehorn, Mic ... | R01ES007061 | J Biol Chem (2012 Jan 06) |
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| Activation of protein kinase Tel1 through recognition of protein-bound DNA ends. | Fukunaga, Kenzo; Kwon, Youngho; Sung, Patrick; Sugimoto, Katsunori | R01ES007061 | Mol Cell Biol (2011 May) |
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| Analyses of the yeast Rad51 recombinase A265V mutant reveal different in vivo roles of Swi2-like fac ... | Chi, Peter; Kwon, YoungHo; Visnapuu, Mari-Liis; Lam, Isabel; Santa Maria, Sergio R; Zheng, Xiu ... | R01ES007061 | Nucleic Acids Res (2011 Aug) |
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| Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylatio ... | Chen, Xuefeng; Niu, Hengyao; Chung, Woo-Hyun; Zhu, Zhu; Papusha, Alma; Shim, Eun Yong; Lee, S ... | R01ES007061 | Nat Struct Mol Biol (2011 Sep) |
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| Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter. | Lu, Yuhong; Chu, Adrian; Turker, Mitchell S; Glazer, Peter M | R01ES005775 | Mol Cell Biol (2011 Aug) |
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| Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells. | Babar, Imran A; Czochor, Jennifer; Steinmetz, Allison; Weidhaas, Joanne B; Glazer, Peter M; Sla ... | R01ES005775 | Cancer Biol Ther (2011 Nov 15) |
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| Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51 ... | Dray, Eloïse; Dunlop, Myun Hwa; Kauppi, Liisa; San Filippo, Joseph; Wiese, Claudia; Tsai, Miaw ... | R01ES007061 | Proc Natl Acad Sci U S A (2011 Mar 01) |
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| Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in ... | Kochenova, O V; Soshkina, J V; Stepchenkova, E I; Inge-Vechtomov, S G; Shcherbakova, P V | R01ES015869 | Biochemistry (Mosc) (2011 Jan) |
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| Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protei ... | Zheng, Xiao-Feng; Prakash, Rohit; Saro, Dorina; Longerich, Simonne; Niu, Hengyao; Sung, Patric ... | R01ES007061 | DNA Repair (Amst) (2011 Oct 10) |
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| RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserve ... | Dunlop, Myun Hwa; Dray, Eloïse; Zhao, Weixing; Tsai, Miaw-Sheue; Wiese, Claudia; Schild, David ... | R01ES007061 | J Biol Chem (2011 Oct 28) |
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| The Rad50 coiled-coil domain is indispensable for Mre11 complex functions. | Hohl, Marcel; Kwon, Youngho; Galván, Sandra Muñoz; Xue, Xiaoyu; Tous, Cristina; Aguilera, Andr ... | R01ES007061 | Nat Struct Mol Biol (2011 Sep 04) |
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| A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in ... | Daee, Danielle L; Mertz, Tony M; Shcherbakova, Polina V | R01ES015869 | Proc Natl Acad Sci U S A (2010 Jan 5) |
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| DNA polymerases at the eukaryotic fork-20 years later. | Pavlov, Youri I; Shcherbakova, Polina V | R01ES015869 | Mutat Res (2010 Mar 01) |
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| MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via ... | Singh, Thiyam Ramsing; Saro, Dorina; Ali, Abdullah Mahmood; Zheng, Xiao-Feng; Du, Chang-hu; Kil ... | R01ES007061 | Mol Cell (2010 Mar 26) |
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2007 |
| Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia. | Bindra, R S; Glazer, P M | R01ES005775 | Oncogene (2007 Mar 29) |
17001309
|
2007 |
| Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous ... | Zhang, Yu; Hefferin, Melissa L; Chen, Ling; Shim, Eun Yong; Tseng, Hui-Min; Kwon, Youngho; Sun ... | R01ES007061 | Nat Struct Mol Biol (2007 Jul) |
17589524
|
2007 |
| Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites. | Bindra, Ranjit S; Glazer, Peter M | R01ES005775 | Cancer Biol Ther (2006 Oct) |
17106239
|
2006 |
| CHK2-dependent phosphorylation of BRCA1 in hypoxia. | Gibson, Shannon L; Bindra, Ranjit S; Glazer, Peter M | R01ES005775 | Radiat Res (2006 Oct) |
17007555
|
2006 |
| Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, ... | Hegan, Denise Campisi; Narayanan, Latha; Jirik, Frank R; Edelmann, Winfried; Liskay, R Michael; ... | R01ES005775 | Carcinogenesis (2006 Dec) |
16728433
|
2006 |
| Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage toler ... | Gibson, Shannon L; Narayanan, Latha; Hegan, Denise Campisi; Buermeyer, Andrew B; Liskay, R Mich ... | R01ES005775 | Cancer Lett (2006 Dec 8) |
16426742
|
2006 |
| RecA acts in trans to allow replication of damaged DNA by DNA polymerase V. | Schlacher, Katharina; Cox, Michael M; Woodgate, Roger; Goodman, Myron F | R01ES029680 | Nature (2006 Aug 24) |
16929290
|
2006 |
| Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide. | San Filippo, Joseph; Chi, Peter; Sehorn, Michael G; Etchin, Julia; Krejci, Lumir; Sung, Patric ... | R01ES007061 | J Biol Chem (2006 Apr 28) |
16513631
|
2006 |
| Roles of ATP binding and ATP hydrolysis in human Rad51 recombinase function. | Chi, Peter; Van Komen, Stephen; Sehorn, Michael G; Sigurdsson, Stefan; Sung, Patrick | R01ES007061 | DNA Repair (Amst) (2006 Mar 7) |
16388992
|
2006 |
| Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad ... | Chi, Peter; Kwon, Youngho; Seong, Changhyun; Epshtein, Anastasiya; Lam, Isabel; Sung, Patrick; ... | R01ES007061 | J Biol Chem (2006 Sep 08) |
16831867
|
2006 |
| Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair ... | Chen, Ling; Trujillo, Kelly M; Van Komen, Stephen; Roh, Dong Hyun; Krejci, Lumir; Lewis, L Kev ... | R01ES007061 | J Biol Chem (2005 Jan 28) |
15546877
|
2005 |
| Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells. | Meng, Alice X; Jalali, Farid; Cuddihy, Andrew; Chan, Norman; Bindra, Ranjit S; Glazer, Peter M ... | R01ES005775 | Radiother Oncol (2005 Aug) |
16026872
|
2005 |
| Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. | Bindra, Ranjit S; Gibson, Shannon L; Meng, Alice; Westermark, Ulrica; Jasin, Maria; Pierce, An ... | R01ES005775 | Cancer Res (2005 Dec 15) |
16357170
|
2005 |
| Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner. | Gibson, Shannon L; Bindra, Ranjit S; Glazer, Peter M | R01ES005775 | Cancer Res (2005 Dec 1) |
16322218
|
2005 |
| Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidanc ... | Prakash, Rohit; Krejci, Lumir; Van Komen, Stephen; Anke Schürer, Kirsten; Kramer, Wilfried; Sun ... | R01ES007061 | J Biol Chem (2005 Mar 04) |
15634678
|
2005 |
| Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced throug ... | Jensen, Ryan; Glazer, Peter M | R01ES005775 | Proc Natl Acad Sci U S A (2004 Apr 20) |
15069205
|
2004 |
| Differential arrangements of conserved building blocks among homologs of the Rad50/Mre11 DNA repair ... | de Jager, Martijn; Trujillo, Kelly M; Sung, Patrick; Hopfner, Karl-Peter; Carney, James P; Tain ... | R01ES007061 | J Mol Biol (2004 Jun 11) |
15165861
|
2004 |
| Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. | Bindra, Ranjit S; Schaffer, Paul J; Meng, Alice; Woo, Jennifer; Måseide, Kårstein; Roth, Matt ... | R01ES005775 | Mol Cell Biol (2004 Oct) |
15367671
|
2004 |
| Meiotic recombination: an affair of two recombinases. | Sehorn, Michael G; Sung, Patrick | R01ES007061 | Cell Cycle (2004 Nov) |
15547324
|
2004 |
| Multiple interactions with the Rad51 recombinase govern the homologous recombination function of Rad ... | Raschle, Markus; Van Komen, Stephen; Chi, Peter; Ellenberger, Tom; Sung, Patrick | R01ES007061 | J Biol Chem (2004 Dec 10) |
15465810
|
2004 |
| Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52. | Motycka, Teresa A; Bessho, Tadayoshi; Post, Sean M; Sung, Patrick; Tomkinson, Alan E | R01ES007061 | J Biol Chem (2004 Apr 02) |
14734547
|
2004 |
| Role of ATP hydrolysis in the antirecombinase function of Saccharomyces cerevisiae Srs2 protein. | Krejci, Lumir; Macris, Margaret; Li, Ying; Van Komen, Stephen; Villemain, Jana; Ellenberger, T ... | R01ES007061 | J Biol Chem (2004 May 28) |
15047689
|
2004 |
| Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand break ... | Lewis, L Kevin; Storici, Francesca; Van Komen, Stephen; Calero, Shanna; Sung, Patrick; Resnick, ... | R01ES007061 | Genetics (2004 Apr) |
15126391
|
2004 |
| ATPase and DNA helicase activities of the Saccharomyces cerevisiae anti-recombinase Srs2. | Van Komen, Stephen; Reddy, Mothe Sreedhar; Krejci, Lumir; Klein, Hannah; Sung, Patrick | R01ES007061 | J Biol Chem (2003 Nov 07) |
12966095
|
2003 |
| Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. | Mihaylova, Valia T; Bindra, Ranjit S; Yuan, Jianling; Campisi, Denise; Narayanan, Latha; Jensen ... | R01ES005775 | Mol Cell Biol (2003 May) |
12697826
|
2003 |
| Rad51 recombinase and recombination mediators. | Sung, Patrick; Krejci, Lumir; Van Komen, Stephen; Sehorn, Michael G | R01ES007061 | J Biol Chem (2003 Oct 31) |
12912992
|
2003 |
| Yeast xrs2 binds DNA and helps target rad50 and mre11 to DNA ends. | Trujillo, Kelly M; Roh, Dong Hyun; Chen, Ling; Van Komen, Stephen; Tomkinson, Alan; Sung, Patr ... | R01ES007061 | J Biol Chem (2003 Dec 05) |
14522986
|
2003 |
| Functional cross-talk among Rad51, Rad54, and replication protein A in heteroduplex DNA joint format ... | Van Komen, Stephen; Petukhova, Galina; Sigurdsson, Stefan; Sung, Patrick | R01ES007061 | J Biol Chem (2002 Nov 15) |
12226081
|
2002 |
| Interaction with Rad51 is indispensable for recombination mediator function of Rad52. | Krejci, Lumir; Song, Binwei; Bussen, Wendy; Rothstein, Rodney; Mortensen, Uffe H; Sung, Patric ... | R01ES007061 | J Biol Chem (2002 Oct 18) |
12171935
|
2002 |
| ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiat ... | Peretz, S; Jensen, R; Baserga, R; Glazer, P M | R01ES005775 | Proc Natl Acad Sci U S A (2001 Feb 13) |
11172010
|
2001 |
| Basis for avid homologous DNA strand exchange by human Rad51 and RPA. | Sigurdsson, S; Trujillo, K; Song, B; Stratton, S; Sung, P | R01ES007061 | J Biol Chem (2001 Mar 23) |
11124265
|
2001 |
| DNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hy ... | Rice, K P; Eggler, A L; Sung, P; Cox, M M | R01ES007061 | J Biol Chem (2001 Oct 19) |
11504729
|
2001 |
| DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex. | Trujillo, K M; Sung, P | R01ES007061 | J Biol Chem (2001 Sep 21) |
11454871
|
2001 |
| Hypermutability to ionizing radiation in mismatch repair-deficient, Pms2 knockout mice. | Xu, X S; Narayanan, L; Dunklee, B; Liskay, R M; Glazer, P M | R01ES005775 | Cancer Res (2001 May 1) |
11325851
|
2001 |
| Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange. | Sigurdsson, S; Van Komen, S; Bussen, W; Schild, D; Albala, J S; Sung, P | R01ES007061 | Genes Dev (2001 Dec 15) |
11751636
|
2001 |
| Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. | Chen, L; Trujillo, K; Ramos, W; Sung, P; Tomkinson, A E | R01ES007061 | Mol Cell (2001 Nov) |
11741545
|
2001 |
| Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microsco ... | Anderson, D E; Trujillo, K M; Sung, P; Erickson, H P | R01ES007061 | J Biol Chem (2001 Oct 05) |
11470800
|
2001 |
| Functional interactions among yeast Rad51 recombinase, Rad52 mediator, and replication protein A in ... | Song, B; Sung, P | R01ES007061 | J Biol Chem (2000 May 26) |
10748203
|
2000 |
| Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase. | Chen, L; Trujillo, K; Sung, P; Tomkinson, A E | R01ES007061 | J Biol Chem (2000 Aug 25) |
10854421
|
2000 |
| Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways. | Zeng, M; Narayanan, L; Xu, X S; Prolla, T A; Liskay, R M; Glazer, P M | R01ES005775 | Cancer Res (2000 Sep 1) |
10987303
|
2000 |
| Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions an ... | Andrew, S E; Xu, X S; Baross-Francis, A; Narayanan, L; Milhausen, K; Liskay, R M; Jirik, F R; ... | R01ES005775 | Carcinogenesis (2000 Jul) |
10874005
|
2000 |
| Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1. | Petukhova, G; Sung, P; Klein, H | R01ES007061 | Genes Dev (2000 Sep 01) |
10970884
|
2000 |
| Recombination factors of Saccharomyces cerevisiae. | Sung, P; Trujillo, K M; Van Komen, S | R01ES007061 | Mutat Res (2000 Jun 30) |
10915877
|
2000 |
| Superhelicity-driven homologous DNA pairing by yeast recombination factors Rad51 and Rad54. | Van Komen, S; Petukhova, G; Sigurdsson, S; Stratton, S; Sung, P | R01ES007061 | Mol Cell (2000 Sep) |
11030336
|
2000 |
| Different mutator phenotypes in Mlh1- versus Pms2-deficient mice. | Yao, X; Buermeyer, A B; Narayanan, L; Tran, D; Baker, S M; Prolla, T A; Glazer, P M; Liskay, ... | R01ES005775 | Proc Natl Acad Sci U S A (1999 Jun 08) |
10359802
|
1999 |
| Single strand DNA binding and annealing activities in the yeast recombination factor Rad59. | Petukhova, G; Stratton, S A; Sung, P | R01ES007061 | J Biol Chem (1999 Nov 26) |
10567339
|
1999 |
| The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 c ... | Clairmont, C A; Narayanan, L; Sun, K W; Glazer, P M; Sweasy, J B | R01ES005775 | Proc Natl Acad Sci U S A (1999 Aug 17) |
10449735
|
1999 |
| Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA ... | Petukhova, G; Van Komen, S; Vergano, S; Klein, H; Sung, P | R01ES007061 | J Biol Chem (1999 Oct 08) |
10506208
|
1999 |
| Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95 ... | Trujillo, K M; Yuan, S S; Lee, E Y; Sung, P | R01ES007061 | J Biol Chem (1998 Aug 21) |
9705271
|
1998 |
| Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pm ... | Narayanan, L; Fritzell, J A; Baker, S M; Liskay, R M; Glazer, P M | R01ES005775 | Proc Natl Acad Sci U S A (1997 Apr 01) |
9096356
|
1997 |
| Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinas ... | Sung, P | R01ES007061 | J Biol Chem (1997 Nov 07) |
9353267
|
1997 |
| Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local bre ... | Turner, B C; Haffty, B G; Narayanan, L; Yuan, J; Havre, P A; Gumbs, A A; Kaplan, L; Burgaud, ... | R01ES005775 | Cancer Res (1997 Aug 1) |
9242428
|
1997 |
| Role of DNA mismatch repair in the cytotoxicity of ionizing radiation. | Fritzell, J A; Narayanan, L; Baker, S M; Bronner, C E; Andrew, S E; Prolla, T A; Bradley, A; ... | R01ES005775 | Cancer Res (1997 Nov 15) |
9371516
|
1997 |
| Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promo ... | Sung, P | R01ES007061 | Genes Dev (1997 May 01) |
9159392
|
1997 |
| Dual requirement for the yeast MMS19 gene in DNA repair and RNA polymerase II transcription. | Lauder, S; Bankmann, M; Guzder, S N; Sung, P; Prakash, L; Prakash, S | R01ES007061 | Mol Cell Biol (1996 Dec) |
8943333
|
1996 |
| Frequent spontaneous deletions at a shuttle vector locus in transgenic mice. | Leach, E G; Gunther, E J; Yeasky, T M; Gibson, L H; Yang-Feng, T L; Glazer, P M | R01ES005775 | Mutagenesis (1996 Jan) |
8671715
|
1996 |
| Genetic instability induced by the tumor microenvironment. | Reynolds, T Y; Rockwell, S; Glazer, P M | R01ES005775 | Cancer Res (1996 Dec 15) |
8971187
|
1996 |
| Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequenc ... | Raha, M; Wang, G; Seidman, M M; Glazer, P M | R01ES005775 | Proc Natl Acad Sci U S A (1996 Apr 02) |
8610147
|
1996 |
| Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair. | Wang, G; Seidman, M M; Glazer, P M | R01ES005775 | Science (1996 Feb 09) |
8628995
|
1996 |
| Recombination induced by triple-helix-targeted DNA damage in mammalian cells. | Faruqi, A F; Seidman, M M; Segal, D J; Carroll, D; Glazer, P M | R01ES005775 | Mol Cell Biol (1996 Dec) |
8943337
|
1996 |
| Targeted mutagenesis mediated by the triple helix formation. | Glazer, P M; Wang, G; Havre, P A; Gunther, E J | R01ES005775 | Methods Mol Biol (1996) |
8849999
|
1996 |
| Tissue specificity of spontaneous point mutations in lambda supF transgenic mice. | Leach, E G; Narayanan, L; Havre, P A; Gunther, E J; Yeasky, T M; Glazer, P M | R01ES005775 | Environ Mol Mutagen (1996) |
8991078
|
1996 |
| Yeast Rad51 recombinase mediates polar DNA strand exchange in the absence of ATP hydrolysis. | Sung, P; Stratton, S A | R01ES007061 | J Biol Chem (1996 Nov 08) |
8910403
|
1996 |
| Altered repair of targeted psoralen photoadducts in the context of an oligonucleotide-mediated tripl ... | Wang, G; Glazer, P M | R01ES005775 | J Biol Chem (1995 Sep 22) |
7673252
|
1995 |
| DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that ... | Sung, P; Robberson, D L | R01ES007061 | Cell (1995 Aug 11) |
7634335
|
1995 |
| Frequent T:A-->G:C transversions in X-irradiated mouse cells. | Yuan, J; Yeasky, T M; Rhee, M C; Glazer, P M | R01ES005775 | Carcinogenesis (1995 Jan) |
7834808
|
1995 |
| Induction of p53 in mouse cells decreases mutagenesis by UV radiation. | Yuan, J; Yeasky, T M; Havre, P A; Glazer, P M | R01ES005775 | Carcinogenesis (1995 Oct) |
7586125
|
1995 |
| Mutagenesis by 8-methoxypsoralen and 5-methylangelicin photoadducts in mouse fibroblasts: mutations ... | Gunther, E J; Yeasky, T M; Gasparro, F P; Glazer, P M | R01ES005775 | Cancer Res (1995 Mar 15) |
7882323
|
1995 |
| Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation. | Wang, G; Levy, D D; Seidman, M M; Glazer, P M | R01ES005775 | Mol Cell Biol (1995 Mar) |
7862165
|
1995 |
| Site-specific targeting of psoralen photoadducts with a triple helix-forming oligonucleotide: charac ... | Gasparro, F P; Havre, P A; Olack, G A; Gunther, E J; Glazer, P M | R01ES005775 | Nucleic Acids Res (1994 Jul 25) |
8052539
|
1994 |
| High efficiency, restriction-deficient in vitro packaging extracts for bacteriophage lambda DNA usin ... | Gunther, E J; Murray, N E; Glazer, P M | R01ES005775 | Nucleic Acids Res (1993 Aug 11) |
8396240
|
1993 |
| Targeted mutagenesis of DNA using triple helix-forming oligonucleotides linked to psoralen. | Havre, P A; Gunther, E J; Gasparro, F P; Glazer, P M | R01ES005775 | Proc Natl Acad Sci U S A (1993 Aug 15) |
8356097
|
1993 |
| Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide. | Havre, P A; Glazer, P M | R01ES005775 | J Virol (1993 Dec) |
8230456
|
1993 |