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Who We Fund: Publications associated with Basic Cellular And Molecular Research - Genome Integrity

These search results have not been confirmed by NIEHS and are therefore, not official. They are to be used only for general information and to inform the public and grantees on the breadth of research funded by NIEHS.

Viewing 679 publications
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Publication Title Authors Grant Number(s) Journal (Pub date) PubMed Link Pub Year
A new technique for genome-wide mapping of nucleotide excision repair without immunopurification of ...   Wu, Sizhong; Huang, Yanchao; Selby, Christopher P; Gao, Meng; Sancar, Aziz; Hu, Jinchuan R01ES033414 J Biol Chem (2022 Mar 23) 35339490 Exiting the NIEHS site 2022 
ATR activity controls stem cell quiescence via the cyclin F-SCF complex.   Salvi, Jayesh S; Kang, Jengmin; Kim, Soochi; Colville, Alex J; de Morrée, Antoine; Billeskov, ... R01ES016486, R01ES016486 Proc Natl Acad Sci U S A (2022 May 03) 35476521 Exiting the NIEHS site 2022 
Bloom helicase mediates formation of large single-stranded DNA loops during DNA end processing.   Xue, Chaoyou; Salunkhe, Sameer J; Tomimatsu, Nozomi; Kawale, Ajinkya S; Kwon, Youngho; Burma, ... R01ES007061 Nat Commun (2022 Apr 26) 35473934 Exiting the NIEHS site 2022 
Comparing qPCR and DNA methylation-based measurements of telomere length in a high-risk pediatric co ...   Hastings, Waylon J; Etzel, Laura; Heim, Christine M; Noll, Jennie G; Rose, Emma J; Schreier, H ... U01ES030949 Aging (Albany NY) (2022 01 24) 35077392 Exiting the NIEHS site 2022 
CSB-independent, XPC-dependent transcription-coupled repair in Drosophila.   Deger, Nazli; Cao, Xuemei; Selby, Christopher P; Gulec, Saygin; Kawara, Hiroaki; Dewey, Evan B ... R01ES033414 Proc Natl Acad Sci U S A (2022 03 01) 35217627 Exiting the NIEHS site 2022 
dCas9 binding inhibits the initiation of base excision repair in vitro.   Antony, Jacob S; Roberts, Steven A; Wyrick, John J; Hinz, John M R01ES028698 DNA Repair (Amst) (2022 01) 34847381 Exiting the NIEHS site 2022 
DNA repair phenotype and cancer risk: a systematic review and meta-analysis of 55 case-control studi ...   Wu, Hui-Chen; Kehm, Rebecca; Santella, Regina M; Brenner, David J; Terry, Mary Beth P30ES009089, U01ES029660 Sci Rep (2022 03 01) 35233009 Exiting the NIEHS site 2022 
Double-strand breaks: When DNA repair events accidentally meet.   Fujii, Shingo; Sobol, Robert W; Fuchs, Robert P P01ES028949, R01ES014811, U01ES029518, U01ES029518 DNA Repair (Amst) (2022 04) 35219626 Exiting the NIEHS site 2022 
Epigenetic Regulation of Nucleotide Excision Repair.   Li, Wentao; Jones, Kyle; Burke, Tyler J; Hossain, Md Akram; Lariscy, Leah R00ES030015, R00ES030015 Front Cell Dev Biol (2022) 35465333 Exiting the NIEHS site 2022 
Facile preparation of model DNA interstrand cross-link repair intermediates using ribonucleotide-con ...   Tang, Jin; Tang, Feng; Zhao, Linlin R35ES031707 DNA Repair (Amst) (2022 03) 35124371 Exiting the NIEHS site 2022 
Functions of ADP-ribose transferases in the maintenance of telomere integrity.   Muoio, Daniela; Laspata, Natalie; Fouquerel, Elise R00ES027028 Cell Mol Life Sci (2022 Mar 29) 35348914 Exiting the NIEHS site 2022 
Genomic landscape of single-stranded DNA gapped intermediates in Escherichia coli.   Pham, Phuong; Shao, Yijun; Cox, Michael M; Goodman, Myron F R35ES028343 Nucleic Acids Res (2022 01 25) 34951472 Exiting the NIEHS site 2022 
Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair protein ...   Kumar, Namrata; Theil, Arjan F; Roginskaya, Vera; Ali, Yasmin; Calderon, Michael; Watkins, Sim ... R35ES031638 Nat Commun (2022 02 21) 35190564 Exiting the NIEHS site 2022 
High-resolution mapping demonstrates inhibition of DNA excision repair by transcription factors.   Duan, Mingrui; Sivapragasam, Smitha; Antony, Jacob S; Ulibarri, Jenna; Hinz, John M; Poon, Gre ... R01ES028698, R01ES032814 Elife (2022 Mar 15) 35289750 Exiting the NIEHS site 2022 
Interlocking activities of DNA polymerase β in the base excision repair pathway.   Kumar, Adarsh; Reed, Andrew J; Zahurancik, Walter J; Daskalova, Sasha M; Hecht, Sidney M; Suo, ... R01ES028271 Proc Natl Acad Sci U S A (2022 03 08) 35238634 Exiting the NIEHS site 2022 
Modelling Chlamydia and HPV co-infection in patient-derived ectocervix organoids reveals distinct ce ...   Koster, Stefanie; Gurumurthy, Rajendra Kumar; Kumar, Naveen; Prakash, Pon Ganish; Dhanraj, Jaya ... P30ES000002, U01ES029520 Nat Commun (2022 02 24) 35210413 Exiting the NIEHS site 2022 
Natural genetic variation as a tool for discovery in Caenorhabditis nematodes.   Andersen, Erik C; Rockman, Matthew V R01ES029930, R21ES031364 Genetics (2022 01 04) 35134197 Exiting the NIEHS site 2022 
Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone.   Coley, Alexander B; Ward, Antonio; Keeton, Adam B; Chen, Xi; Maxuitenko, Yulia; Prakash, Aishw ... R01ES030084, R01ES030084, R35ES031708, R35ES031708 Adv Cancer Res (2022) 35101229 Exiting the NIEHS site 2022 
PMS2 variant results in loss of ATPase activity without compromising mismatch repair.   D'Arcy, Brandon M; Arrington, Jennifer; Weisman, Justin; McClellan, Steven B; Vandana; Yang, Zh ... R01ES030084, R01ES030084, R35ES031708, R35ES031708 Mol Genet Genomic Med (2022 Feb 21) 35189042 Exiting the NIEHS site 2022 
Quantitative proteomics revealed new functions of ALKBH4.   Yu, Kailin; Qi, Tianyu F; Miao, Weili; Liu, Xiaochuan; Wang, Yinsheng R35ES031707 Proteomics (2022 04) 34951099 Exiting the NIEHS site 2022 
Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments.   Meir, Aviv; Crickard, J Brooks; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Proc Natl Acad Sci U S A (2022 01 25) 35042797 Exiting the NIEHS site 2022 
Rapid Isolation of Wild Nematodes by Baermann Funnel.   Tintori, Sophia C; Sloat, Solomon A; Rockman, Matthew V R21ES031364 J Vis Exp (2022 01 31) 35156660 Exiting the NIEHS site 2022 
SARS-CoV-2 hijacks host cell genome instability pathways.   Victor, Joshua; Jordan, Tristan; Lamkin, Erica; Ikeh, Kanayo; March, Anthony; Frere, Justin; C ... R00ES027028 Res Sq (2022 Apr 14) 35441168 Exiting the NIEHS site 2022 
Set2 histone methyltransferase regulates transcription coupled-nucleotide excision repair in yeast.   Selvam, Kathiresan; Plummer, Dalton A; Mao, Peng; Wyrick, John J R01ES028698, R01ES032814 PLoS Genet (2022 03) 35263330 Exiting the NIEHS site 2022 
Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mu ...   Sun, Shixiang; Brazhnik, Kristina; Lee, Moonsook; Maslov, Alexander Y; Zhang, Yi; Huang, Zhenq ... U01ES029519 J Clin Invest (2022 03 01) 35025760 Exiting the NIEHS site 2022 
Single-molecule, quantitative detection of low-abundance somatic mutations by high-throughput sequen ...   Maslov, Alexander Y; Makhortov, Sergey; Sun, Shixiang; Heid, Johanna; Dong, Xiao; Lee, Moonsoo ... U01ES029519 Sci Adv (2022 04 08) 35394831 Exiting the NIEHS site 2022 
SomaMutDB: a database of somatic mutations in normal human tissues.   Sun, Shixiang; Wang, Yujue; Maslov, Alexander Y; Dong, Xiao; Vijg, Jan U01ES029519 Nucleic Acids Res (2022 01 07) 34634815 Exiting the NIEHS site 2022 
Structures of LIG1 engaging with mutagenic mismatches inserted by polβ in base excision repair.   Caglayan, Melike R00ES026191 FASEB J (2022 May) 35553977 Exiting the NIEHS site 2022 
Targeted Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Accompanied with Radiore ...   Qi, Tianyu F; Miao, Weili; Wang, Yinsheng R35ES031707 Anal Chem (2022 01 25) 35021009 Exiting the NIEHS site 2022 
The Cooked Meat Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine Hair Dosimeter, DNA Adduc ...   Guo, Jingshu; Koopmeiners, Joseph S; Walmsley, Scott J; Villalta, Peter W; Yao, Lihua; Murugan, ... R01ES019564, R03ES031188, U2CES026533 Chem Res Toxicol (2022 May 16) 35446561 Exiting the NIEHS site 2022 
The mRNA tether model for activation-induced deaminase and its relevance for Ig somatic hypermutatio ...   Liu, Di; Goodman, Myron F; Pham, Phuong; Yu, Kefei; Hsieh, Chih-Lin; Lieber, Michael R R35ES028343 DNA Repair (Amst) (2022 02) 34990960 Exiting the NIEHS site 2022 
The Role of DNA Repair in Immunological Diversity: From Molecular Mechanisms to Clinical Ramificatio ...   Gullickson, Peter; Xu, Yunwen W; Niedernhofer, Laura J; Thompson, Elizabeth L; Yousefzadeh, Mat ... U01ES029603 Front Immunol (2022) 35432317 Exiting the NIEHS site 2022 
Transcriptional regulation via strand displacement DNA repair in G-quadruplexes.   Whitaker, Amy; Freudenthal, Bret R01ES029203 FASEB J (2022 May) 35556471 Exiting the NIEHS site 2022 
USP1-trapping lesions as a source of DNA replication stress and genomic instability.   Coleman, Kate E; Yin, Yandong; Lui, Sarah Kit Leng; Keegan, Sarah; Fenyo, David; Smith, Duncan ... R01ES025166, R01ES031658 Nat Commun (2022 04 01) 35365626 Exiting the NIEHS site 2022 
A basal-level activity of ATR links replication fork surveillance and stress response.   Yin, Yandong; Lee, Wei Ting Chelsea; Gupta, Dipika; Xue, Huijun; Tonzi, Peter; Borowiec, James ... R01ES031658 Mol Cell (2021 10 21) 34473946 Exiting the NIEHS site 2021 
A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease ...   Patchett, Stephanie; Lv, Zongyang; Rut, Wioletta; Békés, Miklos; Drag, Marcin; Olsen, Shaun K; ... R01ES025166 Cell Rep (2021 09 28) 34547223 Exiting the NIEHS site 2021 
A Quantitative Proteomic Approach for the Identification of DNA Guanine Quadruplex-Binding Proteins.   Gao, Zi; Williams, Preston; Li, Lin; Wang, Yinsheng R35ES031707 J Proteome Res (2021 11 05) 34570971 Exiting the NIEHS site 2021 
Aldehyde dehydrogenase inhibitors promote DNA damage in ovarian cancer and synergize with ATM/ATR in ...   Grimley, Edward; Cole, Alexander J; Luong, Thong T; McGonigal, Stacy C; Sinno, Sarah; Yang, Do ... R01ES030335 Theranostics (2021) 33664846 Exiting the NIEHS site 2021 
Alkylating and oxidative stresses in smoking and non-smoking patients with COPD: Implications for lu ...   Shih, Ying-Ming; Chang, Yuan-Jhe; Cooke, Marcus S; Pan, Chih-Hong; Hu, Ching-Hsuan; Chao, Mu-R ... R01ES030557 Free Radic Biol Med (2021 02 20) 33418114 Exiting the NIEHS site 2021 
Altered APE1 activity on abasic ribonucleotides is mediated by changes in the nucleoside sugar pucke ...   Hoitsma, Nicole M; Click, Timothy H; Agarwal, Pratul K; Freudenthal, Bret D R01ES029203 Comput Struct Biotechnol J (2021) 34188778 Exiting the NIEHS site 2021 
An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site confo ...   Nguyen, My T; Moiani, Davide; Ahmed, Zamal; Arvai, Andrew S; Namjoshi, Sarita; Shin, Dave S; F ... P30ES000002, U01ES029520 Prog Biophys Mol Biol (2021 08) 33675849 Exiting the NIEHS site 2021 
APE2 Is a General Regulator of the ATR-Chk1 DNA Damage Response Pathway to Maintain Genome Integrity ...   Hossain, Md Akram; Lin, Yunfeng; Driscoll, Garrett; Li, Jia; McMahon, Anne; Matos, Joshua; Zha ... R21ES032966 Front Cell Dev Biol (2021) 34796173 Exiting the NIEHS site 2021 
Ascorbate: antioxidant and biochemical activities and their importance for in vitro models.   Zhitkovich, Anatoly R01ES028072, R01ES028072, R01ES031002, R01ES031002, R01ES031979, R01ES031979 Arch Toxicol (2021 Dec) 34596731 Exiting the NIEHS site 2021 
Biochemical and photochemical mechanisms that produce different UV-induced mutation spectra.   Sugiyama, Tomohiko; Keinard, Brianna; Best, Griffin; Sanyal, Mahima R R15ES029723, R15ES029723 Mutat Res (2021 Jul-Dec) 34563793 Exiting the NIEHS site 2021 
Biomarkers of nucleic acid oxidation - A summary state-of-the-art.   Chao, Mu-Rong; Evans, Mark D; Hu, Chiung-Wen; Ji, Yunhee; Møller, Peter; Rossner, Pavel; Cooke ... R01ES030557 Redox Biol (2021 06) 33579665 Exiting the NIEHS site 2021 
Chemoproteomic Approach toward Probing the Interactomes of Perfluoroalkyl Substances.   Zhang, Quanqing; Dong, Xuejiao; Lu, Jiuwei; Song, Jikui; Wang, Yinsheng R35ES031707 Anal Chem (2021 07 13) 34185510 Exiting the NIEHS site 2021 
Circadian clock, carcinogenesis, chronochemotherapy connections.   Yang, Yanyan; Lindsey-Boltz, Laura A; Vaughn, Courtney M; Selby, Christopher P; Cao, Xuemei; Li ... R01ES027255, R01ES033414 J Biol Chem (2021 09) 34375638 Exiting the NIEHS site 2021 
Clocks, cancer, and chronochemotherapy.   Sancar, Aziz; Van Gelder, Russell N R01ES027255 Science (2021 01 01) 33384351 Exiting the NIEHS site 2021 
CometChip analysis of human primary lymphocytes enables quantification of inter-individual differenc ...   Ngo, Le P; Kaushal, Simran; Chaim, Isaac A; Mazzucato, Patrizia; Ricciardi, Catherine; Samson, ... P30ES000002, P30ES002109, U01ES029520 Free Radic Biol Med (2021 10) 34324980 Exiting the NIEHS site 2021 
Comparative analyses of two primate species diverged by more than 60 million years show different ra ...   Akkose, Umit; Kaya, Veysel Ogulcan; Lindsey-Boltz, Laura; Karagoz, Zeynep; Brown, Adam D; Larse ... R01ES027255, R01ES033414 BMC Genomics (2021 Aug 06) 34362292 Exiting the NIEHS site 2021 
Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positi ...   Stepchenkova, Elena I; Zhuk, Anna S; Cui, Jian; Tarakhovskaya, Elena R; Barbari, Stephanie R; S ... R01ES015869 Genetics (2021 06 24) 33844024 Exiting the NIEHS site 2021 
Comprehensive Analysis of DNA Adducts Using Data-Independent wSIM/MS2 Acquisition and wSIM-City.   Walmsley, Scott J; Guo, Jingshu; Murugan, Paari; Weight, Christopher J; Wang, Jinhua; Villalta, ... R01ES019564, R01ES030765, R03ES031188, U2CES026533 Anal Chem (2021 04 27) 33844920 Exiting the NIEHS site 2021 
Conceptual and analytical overlap between allostatic load and systemic biological aging measures: An ...   Hastings, Waylon J; Almeida, David M; Shalev, Idan U01ES030949 J Gerontol A Biol Sci Med Sci (2021 Jun 28) 34180993 Exiting the NIEHS site 2021 
Construction of a Three-Color Prism-Based TIRF Microscope to Study the Interactions and Dynamics of ...   Fairlamb, Max S; Whitaker, Amy M; Bain, Fletcher E; Spies, Maria; Freudenthal, Bret D R01ES029203 Biology (Basel) (2021 Jun 23) 34201434 Exiting the NIEHS site 2021 
CRISPR screens guide the way for PARP and ATR inhibitor biomarker discovery.   Schleicher, Emily M; Moldovan, George-Lucian R01ES026184, R01ES026184 FEBS J (2021 Oct 03) 34601817 Exiting the NIEHS site 2021 
CTCF binding modulates UV damage formation to promote mutation hot spots in melanoma.   Sivapragasam, Smitha; Stark, Bastian; Albrecht, Amanda V; Bohm, Kaitlynne A; Mao, Peng; Emehise ... R01ES028698, R01ES032814 EMBO J (2021 10 18) 34487363 Exiting the NIEHS site 2021 
Cytotoxicity and genotoxicity of the carcinogen aristolochic acid I (AA-I) in human bladder RT4 cell ...   Bellamri, Medjda; Brandt, Kyle; Brown, Christina V; Wu, Ming-Tsang; Turesky, Robert J R01ES030559 Arch Toxicol (2021 06) 33938965 Exiting the NIEHS site 2021 
Differential immunomodulatory effect of PARP inhibition in BRCA1 deficient and competent tumor cells ...   Alvarado-Cruz, Isabel; Mahmoud, Mariam; Khan, Mohammed; Zhao, Shilin; Oeck, Sebastian; Meas, R ... R35ES031708, R35ES031708 Biochem Pharmacol (2021 02) 33285109 Exiting the NIEHS site 2021 
Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex.   Prakash, Rohit; Sandoval, Thomas; Morati, Florian; Zagelbaum, Jennifer A; Lim, Pei-Xin; White, ... R01ES030335 Nat Commun (2021 07 12) 34253720 Exiting the NIEHS site 2021 
Distinct roles for RSC and SWI/SNF chromatin remodelers in genomic excision repair.   Bohm, Kaitlynne A; Hodges, Amelia J; Czaja, Wioletta; Selvam, Kathiresan; Smerdon, Michael J; M ... R01ES028698 Genome Res (2021 06) 34001524 Exiting the NIEHS site 2021 
DNA damage-how and why we age?   Yousefzadeh, Matt; Henpita, Chathurika; Vyas, Rajesh; Soto-Palma, Carolina; Robbins, Paul; Nied ... U01ES029603 Elife (2021 01 29) 33512317 Exiting the NIEHS site 2021 
DNA glycosylase deficiency leads to decreased severity of lupus in the Polb-Y265C mouse model.   Paluri, Sesha L; Burak, Matthew; Senejani, Alireza G; Levinson, Madison; Rahim, Tania; Clairmon ... R35ES031708, R35ES031708 DNA Repair (Amst) (2021 09) 34186496 Exiting the NIEHS site 2021 
DNA ligase I fidelity mediates the mutagenic ligation of pol β oxidized and mismatch nucleotide inse ...   Kamble, Pradnya; Hall, Kalen; Chandak, Mahesh; Tang, Qun; Çağlayan, Melike R00ES026191 J Biol Chem (2021 Jan-Jun) 33600799 Exiting the NIEHS site 2021 
DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal an ...   Chung, Jiil; Maruvka, Yosef E; Sudhaman, Sumedha; Kelly, Jacalyn; Haradhvala, Nicholas J; Bianc ... R01ES028271 Cancer Discov (2021 05) 33355208 Exiting the NIEHS site 2021 
DNA Polymerase II Supports the Replicative Bypass of N2-Alkyl-2'-deoxyguanosine Lesions in Escherich ...   Wang, Yinan; Wu, Jun; Wu, Jiabin; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2021 03 15) 33417436 Exiting the NIEHS site 2021 
DNA Polymerase η Promotes the Transcriptional Bypass of N2-Alkyl-2'-deoxyguanosine Adducts in Human ...   Tan, Ying; Guo, Su; Wu, Jun; Du, Hua; Li, Lin; You, Changjun; Wang, Yinsheng R35ES031707 J Am Chem Soc (2021 10 06) 34555898 Exiting the NIEHS site 2021 
DNA polymerases η and κ bypass N2-guanine-O6-alkylguanine DNA alkyltransferase cross-linked DNA-pept ...   Ghodke, Pratibha P; Guengerich, F Peter R01ES026955 J Biol Chem (2021 10) 34461101 Exiting the NIEHS site 2021 
DNA Sequence Modulates the Efficiency of NEIL1-Catalyzed Excision of the Aflatoxin B1-Induced Formam ...   Tomar, Rachana; Minko, Irina G; Kellum Jr, Andrew H; Voehler, Markus W; Stone, Michael P; McCul ... R01ES031086 Chem Res Toxicol (2021 03 15) 33595290 Exiting the NIEHS site 2021 
DNA-protein crosslinks are repaired via homologous recombination in mammalian mitochondria.   Chesner, Lisa N; Essawy, Maram; Warner, Cecilia; Campbell, Colin R01ES023350 DNA Repair (Amst) (2021 01) 33316746 Exiting the NIEHS site 2021 
DNMT1 reads heterochromatic H4K20me3 to reinforce LINE-1 DNA methylation.   Ren, Wendan; Fan, Huitao; Grimm, Sara A; Kim, Jae Jin; Li, Linhui; Guo, Yiran; Petell, Christ ... R35ES031707 Nat Commun (2021 05 03) 33941775 Exiting the NIEHS site 2021 
Dynamic Processing of a Common Oxidative DNA Lesion by the First Two Enzymes of the Base Excision Re ...   Raper, Austin T; Maxwell, Brian A; Suo, Zucai R01ES028271 J Mol Biol (2021 03 05) 33450252 Exiting the NIEHS site 2021 
Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-def ...   Mehibel, Manal; Xu, Yu; Li, Caiyun G; Moon, Eui Jung; Thakkar, Kaushik N; Diep, Anh N; Kim, R ... R01ES016486, R01ES016486 J Clin Invest (2021 06 01) 34060485 Exiting the NIEHS site 2021 
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.   Geijer, Marit E; Zhou, Di; Selvam, Kathiresan; Steurer, Barbara; Mukherjee, Chirantani; Evers, ... R01ES028698 Nat Cell Biol (2021 06) 34108662 Exiting the NIEHS site 2021 
Ending a diagnostic odyssey: Moving from exome to genome to identify cockayne syndrome.   Friedman, Jennifer; Bird, Lynne M; Haas, Richard; Robbins, Shira L; Nahas, Shareef A; Dimmock, ... U01ES029603 Mol Genet Genomic Med (2021 07) 34076366 Exiting the NIEHS site 2021 
Environmentally induced ribosomal DNA (rDNA) instability in human cells and populations exposed to h ...   Lou, Jianlin; Yu, Shoukai; Feng, Lingfang; Guo, Xinnian; Wang, Meng; Branco, Alan T; Li, Tao; ... P30ES000002, R01ES027981 Environ Int (2021 08) 33774497 Exiting the NIEHS site 2021 
Enzymatic bypass and the structural basis of miscoding opposite the DNA adduct 1,N2-ethenodeoxyguano ...   Ghodke, Pratibha P; Mali, Jyotirling R; Patra, Amritraj; Rizzo, Carmelo J; Guengerich, F Peter; ... R01ES026955 J Biol Chem (2021 Jan-Jun) 33839151 Exiting the NIEHS site 2021 
Etheno adducts: from tRNA modifications to DNA adducts and back to miscoding ribonucleotides.   Guengerich, F Peter; Ghodke, Pratibha P R01ES026955 Genes Environ (2021 Jun 16) 34130743 Exiting the NIEHS site 2021 
EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication ...   Hambarde, Shashank; Tsai, Chi-Lin; Pandita, Raj K; Bacolla, Albino; Maitra, Anirban; Charaka, ... R01ES029680, R01ES029680 Mol Cell (2021 07 15) 34197737 Exiting the NIEHS site 2021 
Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair.   Thompson, Marlo K; Sobol, Robert W; Prakash, Aishwarya P01ES028949, R01ES014811, R01ES030084, R01ES030084, R35ES031708, R35ES031708, U01ES029518, U01ES029518 Biology (Basel) (2021 Jun 14) 34198612 Exiting the NIEHS site 2021 
Fluorescence Sheds Light on DNA Damage, DNA Repair, and Mutations.   Owiti, Norah A; Nagel, Zachary D; Engelward, Bevin P P30ES000002, U01ES029520, U44ES024698 Trends Cancer (2021 03) 33203608 Exiting the NIEHS site 2021 
Formation and Repair of an Interstrand DNA Cross-Link Arising from a Common Endogenous Lesion.   Housh, Kurt; Jha, Jay S; Yang, Zhiyu; Haldar, Tuhin; Johnson, Kevin M; Yin, Jiekai; Wang, Yin ... R01ES021007, R01ES021007 J Am Chem Soc (2021 09 22) 34516735 Exiting the NIEHS site 2021 
Formation and repair of unavoidable, endogenous interstrand cross-links in cellular DNA.   Housh, Kurt; Jha, Jay S; Haldar, Tuhin; Amin, Saosan Binth Md; Islam, Tanhaul; Wallace, Amanda ... R01ES021007, R01ES021007 DNA Repair (Amst) (2021 02) 33385969 Exiting the NIEHS site 2021 
Fused in sarcoma regulates DNA replication timing and kinetics.   Jia, Weiyan; Kim, Sang Hwa; Scalf, Mark A; Tonzi, Peter; Millikin, Robert J; Guns, William M; ... R01ES025166 J Biol Chem (2021 09) 34375640 Exiting the NIEHS site 2021 
G3BP1 binds to guanine quadruplexes in mRNAs to modulate their stabilities.   He, Xiaomei; Yuan, Jun; Wang, Yinsheng R35ES031707 Nucleic Acids Res (2021 11 08) 34614161 Exiting the NIEHS site 2021 
Genome-wide analysis of 8-oxo-7,8-dihydro-2'-deoxyguanosine at single-nucleotide resolution unveils ...   An, Jiao; Yin, Mengdie; Yin, Jiayong; Wu, Sizhong; Selby, Christopher P; Yang, Yanyan; Sancar, ... R01ES033414 Nucleic Acids Res (2021 12 02) 34788860 Exiting the NIEHS site 2021 
Genome-wide circadian rhythm detection methods: systematic evaluations and practical guidelines.   Mei, Wenwen; Jiang, Zhiwen; Chen, Yang; Chen, Li; Sancar, Aziz; Jiang, Yuchao R01ES027255 Brief Bioinform (2021 05 20) 32672832 Exiting the NIEHS site 2021 
Genome-wide Excision Repair Map of Cyclobutane Pyrimidine Dimers in Arabidopsis and the Roles of CSA ...   Kaya, Sezgi; Adebali, Ogun; Oztas, Onur; Sancar, Aziz R01ES033414 Photochem Photobiol (2021 Sep 15) 34525225 Exiting the NIEHS site 2021 
Genome-wide mapping of genomic DNA damage: methods and implications.   Amente, Stefano; Scala, Giovanni; Majello, Barbara; Azmoun, Somaiyeh; Tempest, Helen G; Premi, ... R01ES030557 Cell Mol Life Sci (2021 Nov) 34463773 Exiting the NIEHS site 2021 
GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health.   Zhao, Yajie; Stankovic, Stasa; Koprulu, Mine; Wheeler, Eleanor; Day, Felix R; Lango Allen, Han ... DP2ES030554 Nat Commun (2021 07 07) 34234147 Exiting the NIEHS site 2021 
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection.   Zekavat, Seyedeh M; Lin, Shu-Hong; Bick, Alexander G; Liu, Aoxing; Paruchuri, Kaavya; Wang, Ch ... DP2ES030554 Nat Med (2021 06) 34099924 Exiting the NIEHS site 2021 
HILIC-MS/MS for the Determination of Methylated Adenine Nucleosides in Human Urine.   Guo, Cheng; Hu, Yiqiu; Cao, Xiaoji; Wang, Yinsheng R01ES029749 Anal Chem (2021 12 28) 34902250 Exiting the NIEHS site 2021 
Impact of Amplification Efficiency Approaches on Telomere Length Measurement via Quantitative-Polyme ...   Hastings, Waylon J; Eisenberg, Dan T A; Shalev, Idan U01ES030949 Front Genet (2021) 34603389 Exiting the NIEHS site 2021 
Impact of DNA sequences on DNA 'opening' by the Rad4/XPC nucleotide excision repair complex.   Paul, Debamita; Mu, Hong; Tavakoli, Amirrasoul; Dai, Qing; Chakraborty, Sagnik; He, Chuan; Ans ... R01ES025987 DNA Repair (Amst) (2021 11) 34428697 Exiting the NIEHS site 2021 
Impact of structural ageism on greater violence against older persons: a cross-national study of 56 ...   Chang, E-Shien; Monin, Joan K; Zelterman, Daniel; Levy, Becca R R01ES005775 BMJ Open (2021 05 13) 33986041 Exiting the NIEHS site 2021 
Insights into the mismatch discrimination mechanism of Y-family DNA polymerase Dpo4.   Jung, Hunmin; Lee, Seongmin R01ES026676 Biochem J (2021 05 14) 33881499 Exiting the NIEHS site 2021 
Insights into the substrate discrimination mechanisms of methyl-CpG-binding domain 4.   Ouzon-Shubeita, Hala; Schmaltz, Lillian F; Lee, Seongmin R01ES026676 Biochem J (2021 05 28) 33960375 Exiting the NIEHS site 2021 
Interstrand Cross-Link Formation Involving Reaction of a Mispaired Cytosine Residue with an Abasic S ...   Varela, Jacqueline Gamboa; Pierce, Luke E; Guo, Xu; Price, Nathan E; Johnson, Kevin M; Yang, Z ... R01ES021007, R01ES021007 Chem Res Toxicol (2021 04 19) 33784065 Exiting the NIEHS site 2021 
Is high resolution a strict requirement for mass spectrometry-based cellular DNA adductomics?   Chang, Yuan-Jhe; Cooke, Marcus S; Chen, Yet-Ran; Yang, Shun-Fa; Li, Pei-Shan; Hu, Chiung-Wen; ... R01ES030557 Chemosphere (2021 Jul) 33979922 Exiting the NIEHS site 2021 
Large mosaic copy number variations confer autism risk.   Sherman, Maxwell A; Rodin, Rachel E; Genovese, Giulio; Dias, Caroline; Barton, Alison R; Mukame ... DP2ES030554 Nat Neurosci (2021 02) 33432194 Exiting the NIEHS site 2021 
Large-scale preparation of fluorescence multiplex host cell reactivation (FM-HCR) reporters.   Piett, C G; Pecen, T J; Laverty, D J; Nagel, Z D P30ES000002, U01ES029520 Nat Protoc (2021 09) 34363069 Exiting the NIEHS site 2021 
Light-induced modulation of DNA recognition by the Rad4/XPC damage sensor protein.   Tavakoli, Amirrasoul; Paul, Debamita; Mu, Hong; Kuchlyan, Jagannath; Baral, Saroj; Ansari, Anj ... R01ES025987 RSC Chem Biol (2021 Apr 01) 34041491 Exiting the NIEHS site 2021 
Long-term survival of an ovarian cancer patient harboring a RAD51C missense mutation.   Sullivan, Meghan R; Prakash, Rohit; Rawal, Yashpal; Wang, Weibin; Sung, Patrick; Radke, Marc R ... R01ES007061, R01ES030335 Cold Spring Harb Mol Case Stud (2021 04) 33832919 Exiting the NIEHS site 2021 
Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability i ...   Jackson, Lindsey M; Dhoonmoon, Ashna; Hale, Anastasia; Dennis, Kady A; Schleicher, Emily M; Nic ... R01ES026184, R01ES026184 Nucleic Acids Res (2021 12 16) 34871431 Exiting the NIEHS site 2021 
m6A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells.   Huff, Sarah; Tiwari, Shashi Kant; Gonzalez, Gwendolyn M; Wang, Yinsheng; Rana, Tariq M R35ES031707, T32ES018827 ACS Chem Biol (2021 02 19) 33412003 Exiting the NIEHS site 2021 
Maintenance of genome sequence integrity in long- and short-lived rodent species.   Zhang, Lei; Dong, Xiao; Tian, Xiao; Lee, Moonsook; Ablaeva, Julia; Firsanov, Denis; Lee, Sang ... U01ES029519 Sci Adv (2021 Oct 29) 34705500 Exiting the NIEHS site 2021 
Mitochondrial Transcription Factor A Binds to and Promotes Mutagenic Transcriptional Bypass of O4-Al ...   He, Xiaomei; Wang, Pengcheng; Wang, Yinsheng R35ES031707 Anal Chem (2021 01 19) 33290046 Exiting the NIEHS site 2021 
Molecular dynamics simulations reveal how H3K56 acetylation impacts nucleosome structure to promote ...   Fu, Iwen; Geacintov, Nicholas E; Broyde, Suse R01ES025987 DNA Repair (Amst) (2021 11) 34399316 Exiting the NIEHS site 2021 
Molecular mechanisms and cardiovascular implications of cancer therapy-induced senescence.   Abdelgawad, Ibrahim Y; Sadak, Karim T; Lone, Diana W; Dabour, Mohamed S; Niedernhofer, Laura J; ... U01ES029603 Pharmacol Ther (2021 05) 33275998 Exiting the NIEHS site 2021 
Monitoring genome-wide replication fork directionality by Okazaki fragment sequencing in mammalian c ...   Kit Leng Lui, Sarah; Keegan, Sarah; Tonzi, Peter; Kahli, Malik; Chen, Yu-Hung; Chalhoub, Noor; ... R01ES025166, R01ES031658 Nat Protoc (2021 02) 33442052 Exiting the NIEHS site 2021 
MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling p ...   Luzwick, Jessica W; Dombi, Eszter; Boisvert, Rebecca A; Roy, Sunetra; Park, Soyoung; Kunnimalai ... R01ES029680, R01ES029680 Sci Adv (2021 Dec 17) 34910513 Exiting the NIEHS site 2021 
Mutperiod: Analysis of periodic mutation rates in nucleosomes.   Morledge-Hampton, Benjamin; Wyrick, John J R01ES028698, R01ES032814 Comput Struct Biotechnol J (2021) 34527191 Exiting the NIEHS site 2021 
NAD+ metabolism controls growth inhibition by HIF1 in normoxia and determines differential sensitivi ...   Luczak, Michal W; Krawic, Casey; Zhitkovich, Anatoly R01ES028072, R01ES028072, R01ES031002, R01ES031002, R01ES031979, R01ES031979 Cell Cycle (2021 09) 34382917 Exiting the NIEHS site 2021 
Noninvasive Assessment of Epidermal Genomic Markers of UV Exposure in Skin.   Muradova, Elnara; Patel, Nishit; Sell, Brittney; Bittencourt, Bruna B; Ojeda, Sandra S; Adelman ... R01ES030562 J Invest Dermatol (2021 01) 32553564 Exiting the NIEHS site 2021 
PARP14 regulates cyclin D1 expression to promote cell-cycle progression.   O'Connor, Michael J; Thakar, Tanay; Nicolae, Claudia M; Moldovan, George-Lucian R01ES026184, R01ES026184 Oncogene (2021 07) 34158578 Exiting the NIEHS site 2021 
PARP1: Structural insights and pharmacological targets for inhibition.   Spiegel, Jacob O; Van Houten, Bennett; Durrant, Jacob D R35ES031638 DNA Repair (Amst) (2021 07) 33940558 Exiting the NIEHS site 2021 
Perspectives on Cyclobutane Pyrimidine Dimers-Rise of the Dark Dimers†.   Lawrence, Karl P; Delinasios, George J; Premi, Sanjay; Young, Antony R; Cooke, Marcus S R01ES030557 Photochem Photobiol (2021 Oct 27) 34706095 Exiting the NIEHS site 2021 
Phosphoinositide 3-Kinase (PI3K) Reactive Oxygen Species (ROS)-Activated Prodrug in Combination with ...   Mishra, Rosalin; Yuan, Long; Patel, Hima; Karve, Aniruddha S; Zhu, Haizhou; White, Aaron; Alan ... R15ES029675, R15ES029675 Int J Mol Sci (2021 Feb 19) 33669867 Exiting the NIEHS site 2021 
Post-transcriptional diversity in riboproteins and RNAs in aging and cancer.   Cruz, Jurandir; Lemos, Bernardo P30ES000002, R01ES027981 Semin Cancer Biol (2021 11) 34474152 Exiting the NIEHS site 2021 
Primary saturation of α, β-unsaturated carbonyl containing fatty acids does not abolish electrophili ...   Snyder, Nathaniel W; O'Brien, James; Singh, Bhupinder; Buchan, Gregory; Arroyo, Alejandro D; Li ... P01ES028949, P30ES013508, U01ES029518, U01ES029518 Chem Biol Interact (2021 Dec 01) 34634267 Exiting the NIEHS site 2021 
Protein-coding repeat polymorphisms strongly shape diverse human phenotypes.   Mukamel, Ronen E; Handsaker, Robert E; Sherman, Maxwell A; Barton, Alison R; Zheng, Yiming; McC ... DP2ES030554 Science (2021 Sep 24) 34554798 Exiting the NIEHS site 2021 
Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genom ...   Geijer, Marit E; Zhou, Di; Selvam, Kathiresan; Steurer, Barbara; Mukherjee, Chirantani; Evers, ... R01ES028698 Nat Cell Biol (2021 Jul) 34163038 Exiting the NIEHS site 2021 
RAD51 paralog function in replicative DNA damage and tolerance.   Rein, Hayley L; Bernstein, Kara A; Baldock, Robert A R01ES030335, R01ES031796 Curr Opin Genet Dev (2021 12) 34311385 Exiting the NIEHS site 2021 
Role and Regulation of the RECQL4 Family during Genomic Integrity Maintenance.   Luong, Thong T; Bernstein, Kara A R01ES030335 Genes (Basel) (2021 11 29) 34946868 Exiting the NIEHS site 2021 
Searching for DNA Damage: Insights From Single Molecule Analysis.   Schaich, Matthew A; Van Houten, Bennett R35ES031638 Front Mol Biosci (2021) 34805281 Exiting the NIEHS site 2021 
Sequence Dependent Repair of 1,N6-Ethenoadenine by DNA Repair Enzymes ALKBH2, ALKBH3, and AlkB.   Qi, Rui; Bian, Ke; Chen, Fangyi; Tang, Qi; Zhou, Xianhao; Li, Deyu R01ES028865, R01ES028865, R01ES028865, R01ES028865 Molecules (2021 Aug 31) 34500720 Exiting the NIEHS site 2021 
Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover.   Jang, Sunbok; Schaich, Matthew A; Khuu, Cindy; Schnable, Brittani L; Majumdar, Chandrima; Watki ... R35ES031638, T32ES007059 Nucleic Acids Res (2021 08 20) 34232996 Exiting the NIEHS site 2021 
Single-molecule imaging reveals replication fork coupled formation of G-quadruplex structures hinder ...   Lee, Wei Ting C; Yin, Yandong; Morten, Michael J; Tonzi, Peter; Gwo, Pam Pam; Odermatt, Diana ... R01ES031658 Nat Commun (2021 05 05) 33953191 Exiting the NIEHS site 2021 
Site-Specific 5-Formyl Cytosine Mediated DNA-Histone Cross-Links: Synthesis and Polymerase Bypass by ...   Pujari, Suresh S; Wu, Mingxuan; Thomforde, Jenna; Wang, Zhipeng A; Chao, Christopher; Olson, N ... R01ES023350 Angew Chem Int Ed Engl (2021 12 13) 34634172 Exiting the NIEHS site 2021 
Super hotspots and super coldspots in the repair of UV-induced DNA damage in the human genome.   Jiang, Yuchao; Li, Wentao; Lindsey-Boltz, Laura A; Yang, Yuchen; Li, Yun; Sancar, Aziz R00ES030015, R00ES030015, R01ES027255 J Biol Chem (2021 Jan-Jun) 33771559 Exiting the NIEHS site 2021 
Synthesis of DNA Duplexes Containing Site-Specific Interstrand Cross-Links via Sequential Reductive ...   Housh, Kurt; Gates, Kent S R01ES021007, R01ES021007 Chem Res Toxicol (2021 11 15) 34694787 Exiting the NIEHS site 2021 
Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly a ...   Koczor, Christopher A; Saville, Kate M; Andrews, Joel F; Clark, Jennifer; Fang, Qingming; Li, ... P01ES028949, R01ES014811, U01ES029518, U01ES029518 Cell Rep (2021 11 02) 34731617 Exiting the NIEHS site 2021 
The central role of DNA damage in the ageing process.   Schumacher, Björn; Pothof, Joris; Vijg, Jan; Hoeijmakers, Jan H J U01ES029519 Nature (2021 04) 33911272 Exiting the NIEHS site 2021 
The emerging determinants of replication fork stability.   Thakar, Tanay; Moldovan, George-Lucian R01ES026184, R01ES026184 Nucleic Acids Res (2021 07 21) 33978751 Exiting the NIEHS site 2021 
The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replis ...   Kumar, Charanya; Batra, Sahil; Griffith, Jack D; Remus, Dirk R01ES031635 Elife (2021 09 08) 34494544 Exiting the NIEHS site 2021 
The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replicati ...   Jiang, Min; Xie, Xie; Zhu, Xuefeng; Jiang, Shan; Milenkovic, Dusanka; Misic, Jelena; Shi, Yon ... R01ES031635 Sci Adv (2021 07) 34215584 Exiting the NIEHS site 2021 
The Rad51 paralog complex Rad55-Rad57 acts as a molecular chaperone during homologous recombination.   Roy, Upasana; Kwon, Youngho; Marie, Lea; Symington, Lorraine; Sung, Patrick; Lisby, Michael; G ... R01ES007061 Mol Cell (2021 03 04) 33421364 Exiting the NIEHS site 2021 
The Role of Senescent Cells in Acquired Drug Resistance and Secondary Cancer in BRAFi-Treated Melano ...   Thompson, Elizabeth L; Hu, Jiayi J; Niedernhofer, Laura J U01ES029603 Cancers (Basel) (2021 May 07) 34066966 Exiting the NIEHS site 2021 
The scaffold protein XRCC1 stabilizes the formation of polβ/gap DNA and ligase IIIα/nick DNA complex ...   Tang, Qun; Çağlayan, Melike R00ES026191 J Biol Chem (2021 09) 34339737 Exiting the NIEHS site 2021 
The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions.   Bonilla, Braulio; Brown, Alexander J; Hengel, Sarah R; Rapchak, Kyle S; Mitchell, Debra; Pressi ... R01ES030335 Elife (2021 11 01) 34723799 Exiting the NIEHS site 2021 
The SOS Error-Prone DNA Polymerase V Mutasome and β-Sliding Clamp Acting in Concert on Undamaged DNA ...   Sikand, Adhirath; Jaszczur, Malgorzata; Bloom, Linda B; Woodgate, Roger; Cox, Michael M; Goodma ... R35ES028343 Cells (2021 05 01) 34062858 Exiting the NIEHS site 2021 
Translesion Synthesis Past 5-Formylcytosine-Mediated DNA-Peptide Cross-Links by hPolη Is Dependent o ...   Thomforde, Jenna; Fu, Iwen; Rodriguez, Freddys; Pujari, Suresh S; Broyde, Suse; Tretyakova, Na ... R01ES023350, R01ES025987 Biochemistry (2021 06 15) 34080848 Exiting the NIEHS site 2021 
Unified exact design with early stopping rules for single arm clinical trials with multiple endpoint ...   Wei, Wei; Esserman, Denise; Kane, Michael; Zelterman, Daniel R01ES005775 Stat Methods Med Res (2021 07) 34159859 Exiting the NIEHS site 2021 
Unravelling roles of error-prone DNA polymerases in shaping cancer genomes.   Vaziri, Cyrus; Rogozin, Igor B; Gu, Qisheng; Wu, Di; Day, Tovah A R01ES029079 Oncogene (2021 12) 34663880 Exiting the NIEHS site 2021 
Versatile cell-based assay for measuring DNA alkylation damage and its repair.   Li, Yong; Mao, Peng; Basenko, Evelina Y; Lewis, Zachary; Smerdon, Michael J; Czaja, Wioletta R21ES028549 Sci Rep (2021 09 15) 34526526 Exiting the NIEHS site 2021 
Vulnerability of IDH1-Mutant Cancers to Histone Deacetylase Inhibition via Orthogonal Suppression of ...   Dow, Jonathan; Krysztofiak, Adam; Liu, Yanfeng; Colon-Rios, Daniel A; Rogers, Faye A; Glazer, ... R01ES005775 Mol Cancer Res (2021 12) 34535560 Exiting the NIEHS site 2021 
Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping ana ...   Barton, Alison R; Sherman, Maxwell A; Mukamel, Ronen E; Loh, Po-Ru DP2ES030554 Nat Genet (2021 08) 34226706 Exiting the NIEHS site 2021 
WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells.   Datta, Arindam; Biswas, Kajal; Sommers, Joshua A; Thompson, Haley; Awate, Sanket; Nicolae, Cla ... R01ES026184, R01ES026184 Nat Commun (2021 11 12) 34772932 Exiting the NIEHS site 2021 
YY1 interacts with guanine quadruplexes to regulate DNA looping and gene expression.   Li, Lin; Williams, Preston; Ren, Wendan; Wang, Michelle Y; Gao, Zi; Miao, Weili; Huang, Ming; ... R35ES031707, T32ES018827 Nat Chem Biol (2021 02) 33199912 Exiting the NIEHS site 2021 
A special issue dedicated to Dr. Bruce N. Ames: Introduction.   Walker, Graham C R35ES028303 Mutat Res Genet Toxicol Environ Mutagen (2020 Jan) 32087846 Exiting the NIEHS site 2020 
A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis.   Chatterjee, Nimrat; D'Souza, Sanjay; Shabab, Mohammad; Harris, Cynthia A; Hilinski, Gerard J; V ... P30ES002109, R35ES028303 Environ Mol Mutagen (2020 10) 32573829 Exiting the NIEHS site 2020 
Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A fram ...   Rut, Wioletta; Lv, Zongyang; Zmudzinski, Mikolaj; Patchett, Stephanie; Nayak, Digant; Snipas, ... R01ES025166 Sci Adv (2020 10) 33067239 Exiting the NIEHS site 2020 
An introduction for the special issue on environmental health and genome integrity.   Yan, Shan; Vaziri, Cyrus R01ES029079 Environ Mol Mutagen (2020 08) 32683747 Exiting the NIEHS site 2020 
Analysis of Telomere Length and Aberrations by Quantitative FISH.   Fouquerel, Elise; Opresko, Patricia R00ES027028 Methods Mol Biol (2020) 31989559 Exiting the NIEHS site 2020 
AP-endonuclease 1 sculpts DNA through an anchoring tyrosine residue on the DNA intercalating loop.   Hoitsma, Nicole M; Whitaker, Amy M; Beckwitt, Emily C; Jang, Sunbok; Agarwal, Pratul K; Van Hou ... R01ES029203 Nucleic Acids Res (2020 07 27) 32542366 Exiting the NIEHS site 2020 
Arsenic Exposure and Compromised Protein Quality Control.   Tam, Lok Ming; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2020 07 20) 32410444 Exiting the NIEHS site 2020 
Arsenite Binds to ZNF598 to Perturb Ribosome-Associated Protein Quality Control.   Tam, Lok Ming; Jiang, Ji; Wang, Pengcheng; Wang, Yinsheng R35ES031707 Chem Res Toxicol (2020 07 20) 32324387 Exiting the NIEHS site 2020 
Asymmetric repair of UV damage in nucleosomes imposes a DNA strand polarity on somatic mutations in ...   Mao, Peng; Smerdon, Michael J; Roberts, Steven A; Wyrick, John J R01ES028698 Genome Res (2020 01) 31871068 Exiting the NIEHS site 2020 
Atypical UV Photoproducts Induce Non-canonical Mutation Classes Associated with Driver Mutations in ...   Laughery, Marian F; Brown, Alexander J; Bohm, Kaitlynne A; Sivapragasam, Smitha; Morris, Haley ... R01ES028698 Cell Rep (2020 11 17) 33207206 Exiting the NIEHS site 2020 
Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenes ...   Galati, Melissa A; Hodel, Karl P; Gams, Miki S; Sudhaman, Sumedha; Bridge, Taylor; Zahurancik, ... R01ES028271 Cancer Res (2020 12 15) 32938641 Exiting the NIEHS site 2020 
Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4.   Ouzon-Shubeita, Hala; Jung, Hunmin; Lee, Michelle H; Koag, Myong-Chul; Lee, Seongmin R01ES026676 Biochem J (2020 05 15) 32297632 Exiting the NIEHS site 2020 
Characterization of Cerebellum-Specific Ribosomal DNA Epigenetic Modifications in Alzheimer's Diseas ...   Faria, Tathyane C; Maldonado, Héctor L; Santos, Leonardo C; DeLabio, Roger; Payao, Spencer L M; ... R01ES027981 Mol Neurobiol (2020 Jun) 32232768 Exiting the NIEHS site 2020 
Characterization of long G4-rich enhancer-associated genomic regions engaging in a novel loop:loop ' ...   Williams, Jonathan D; Houserova, Dominika; Johnson, Bradley R; Dyniewski, Brad; Berroyer, Alexa ... R01ES030084, R01ES030084 Nucleic Acids Res (2020 06 19) 32383760 Exiting the NIEHS site 2020 
Chromatin remodeling and mismatch repair: Access and excision.   Goellner, Eva M R00ES026653 DNA Repair (Amst) (2020 01) 31698199 Exiting the NIEHS site 2020 
Chromosomal alterations among age-related haematopoietic clones in Japan.   Terao, Chikashi; Suzuki, Akari; Momozawa, Yukihide; Akiyama, Masato; Ishigaki, Kazuyoshi; Yamam ... DP2ES030554 Nature (2020 08) 32581364 Exiting the NIEHS site 2020 
Collision-Induced Dissociation Studies of Protonated Ions of Alkylated Thymidine and 2'-Deoxyguanosi ...   Cui, Yuxiang; Yuan, Jun; Wang, Pengcheng; Wu, Jun; Yu, Yang; Wang, Yinsheng R01ES029749 J Am Soc Mass Spectrom (2020 Apr 01) 32134268 Exiting the NIEHS site 2020 
Comparison of the Base Excision and Direct Reversal Repair Pathways for Correcting 1,N6-Ethenoadenin ...   Caffrey, Paul J; Kher, Raadhika; Bian, Ke; Li, Deyu; Delaney, Sarah R01ES028865, R01ES028865, R01ES028865, R01ES028865 Chem Res Toxicol (2020 07 20) 32293880 Exiting the NIEHS site 2020 
Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal M ...   Msaouel, Pavlos; Malouf, Gabriel G; Su, Xiaoping; Yao, Hui; Tripathi, Durga N; Soeung, Melinda ... R01ES029680, R01ES029680 Cancer Cell (2020 05 11) 32359397 Exiting the NIEHS site 2020 
Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo D ...   Gao, Linfeng; Emperle, Max; Guo, Yiran; Grimm, Sara A; Ren, Wendan; Adam, Sabrina; Uryu, Hide ... R35ES031707 Nat Commun (2020 07 03) 32620778 Exiting the NIEHS site 2020 
Cross-linking of the DNA repair protein O6-alkylguanine DNA alkyltransferase to DNA in the presence ...   Ming, Xun; Michaelson-Richie, Erin D; Groehler 4th, Arnold S; Villalta, Peter W; Campbell, Coli ... R01ES023350 DNA Repair (Amst) (2020 05) 32283495 Exiting the NIEHS site 2020 
Defective postreplication repair of UV photoproducts in melanoma: a mutator phenotype.   Brash, Douglas E; Seidman, Michael M R01ES030562 Mol Oncol (2020 01) 31821728 Exiting the NIEHS site 2020 
Detection and Discrimination of DNA Adducts Differing in Size, Regiochemistry, and Functional Group ...   Nookaew, Intawat; Jenjaroenpun, Piroon; Du, Hua; Wang, Pengcheng; Wu, Jun; Wongsurawat, Thidat ... R01ES029749 Chem Res Toxicol (2020 12 21) 32799528 Exiting the NIEHS site 2020 
Development of a DNA Adductome Mass Spectral Database.   Guo, Jingshu; Turesky, Robert J; Tarifa, Anamary; DeCaprio, Anthony P; Cooke, Marcus S; Walmsle ... R01ES019564, R03ES031188 Chem Res Toxicol (2020 04 20) 32223224 Exiting the NIEHS site 2020 
DNA ligase I variants fail in the ligation of mutagenic repair intermediates with mismatches and oxi ...   Tang, Qun; Kamble, Pradnya; Çağlayan, Melike R00ES026191 Mutagenesis (2020 12 01) 32914844 Exiting the NIEHS site 2020 
DNA polymerase δ proofreads errors made by DNA polymerase ε.   Bulock, Chelsea R; Xing, Xuanxuan; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2020 03 17) 32123096 Exiting the NIEHS site 2020 
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the ...   Schleicher, Emily M; Dhoonmoon, Ashna; Jackson, Lindsey M; Clements, Kristen E; Stump, Coryn L; ... R01ES026184, R01ES026184 PLoS Genet (2020 11) 33137164 Exiting the NIEHS site 2020 
Dynamic action of DNA repair proteins as revealed by single molecule techniques: Seeing is believing ...   Kong, Muwen; Beckwitt, Emily C; Van Houten, Bennett R35ES031638 DNA Repair (Amst) (2020 09) 33087275 Exiting the NIEHS site 2020 
Electron microscopic characterization of exhaust particles containing lead dibromide beads expelled ...   Griffith, Jack D R01ES031635 Atmos Pollut Res (2020 Sep) 33100835 Exiting the NIEHS site 2020 
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes.   Rut, Wioletta; Zmudzinski, Mikolaj; Snipas, Scott J; Bekes, Miklos; Huang, Tony T; Drag, Marci ... R01ES025166 Chem Sci (2020 Jun 21) 32953009 Exiting the NIEHS site 2020 
Expanding molecular roles of UV-DDB: Shining light on genome stability and cancer.   Beecher, Maria; Kumar, Namrata; Jang, Sunbok; Rapić-Otrin, Vesna; Van Houten, Bennett R35ES031638 DNA Repair (Amst) (2020 10) 32739133 Exiting the NIEHS site 2020 
Exposure to microplastics cause gut damage, locomotor dysfunction, epigenetic silencing, and aggrava ...   Zhang, Yan; Wolosker, Marina B; Zhao, Yanping; Ren, Hongqiang; Lemos, Bernardo R01ES027981 Sci Total Environ (2020 Nov 20) 32721682 Exiting the NIEHS site 2020 
Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity.   Wilk, Anna; Hayat, Faisal; Cunningham, Richard; Li, Jianfeng; Garavaglia, Silvia; Zamani, Leil ... R01ES014811, U01ES029518, U01ES029518 Sci Rep (2020 01 20) 31959836 Exiting the NIEHS site 2020 
EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excisio ...   Koyen, Allyson E; Madden, Matthew Z; Park, Dongkyoo; Minten, Elizabeth V; Kapoor-Vazirani, Priy ... U01ES029520 Oncogene (2020 06) 32457468 Exiting the NIEHS site 2020 
FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cro ...   Awate, Sanket; Sommers, Joshua A; Datta, Arindam; Nayak, Sumeet; Bellani, Marina A; Yang, Oliv ... R01ES026184, R01ES026184 Nucleic Acids Res (2020 09 18) 32797166 Exiting the NIEHS site 2020 
Functions of the major abasic endonuclease (APE1) in cell viability and genotoxin resistance.   McNeill, Daniel R; Whitaker, Amy M; Stark, Wesley J; Illuzzi, Jennifer L; McKinnon, Peter J; Fr ... R01ES029203 Mutagenesis (2020 02 13) 31816044 Exiting the NIEHS site 2020 
Genetically predicted telomere length is associated with clonal somatic copy number alterations in p ...   Brown, Derek W; Lin, Shu-Hong; Loh, Po-Ru; Chanock, Stephen J; Savage, Sharon A; Machiela, Mit ... DP2ES030554 PLoS Genet (2020 10) 33090998 Exiting the NIEHS site 2020 
Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP1 ...   Dhoonmoon, Ashna; Schleicher, Emily M; Clements, Kristen E; Nicolae, Claudia M; Moldovan, Georg ... R01ES026184, R01ES026184 Nucleic Acids Res (2020 07 27) 32542389 Exiting the NIEHS site 2020 
Genome-Wide Mapping of UV-Induced DNA Damage with CPD-Seq.   Mao, Peng; Wyrick, John J R01ES028698 Methods Mol Biol (2020) 32681485 Exiting the NIEHS site 2020 
Genome-wide role of Rad26 in promoting transcription-coupled nucleotide excision repair in yeast chr ...   Duan, Mingrui; Selvam, Kathiresan; Wyrick, John J; Mao, Peng R01ES028698 Proc Natl Acad Sci U S A (2020 08 04) 32690696 Exiting the NIEHS site 2020 
Genome-wide single-nucleotide resolution of oxaliplatin-DNA adduct repair in drug-sensitive and -res ...   Vaughn, Courtney M; Selby, Christopher P; Yang, Yanyan; Hsu, David S; Sancar, Aziz R01ES027255 J Biol Chem (2020 05 29) 32299912 Exiting the NIEHS site 2020 
Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals withou ...   Natarajan, Pradeep; Zekavat, Seyedeh; Lin, Shu-Hong; Bick, Alexander; Liu, Aoxing; Paruchuri, ... DP2ES030554 Res Sq (2020 Nov 16) 33236004 Exiting the NIEHS site 2020 
Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals withou ...   Zekavat, Seyedeh M; Lin, Shu-Hong; Bick, Alexander G; Liu, Aoxing; Paruchuri, Kaavya; Uddin, M ... DP2ES030554 medRxiv (2020 Nov 16) 33236019 Exiting the NIEHS site 2020 
History of DNA polymerase β X-ray crystallography.   Whitaker, Amy M; Freudenthal, Bret D R01ES029203 DNA Repair (Amst) (2020 09) 33087265 Exiting the NIEHS site 2020 
HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanis ...   Bai, Gongshi; Kermi, Chames; Stoy, Henriette; Schiltz, Carl J; Bacal, Julien; Zaino, Angela M; ... R01ES016486, R01ES016486 Mol Cell (2020 06 18) 32442397 Exiting the NIEHS site 2020 
HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC ...   Mehta, Kavi P M; Lovejoy, Courtney A; Zhao, Runxiang; Heintzman, Darren R; Cortez, David R01ES030575 Cell Rep (2020 06 02) 32492421 Exiting the NIEHS site 2020 
Homologous Recombination Repair Truncations Predict Hypermutation in Microsatellite Stable Colorecta ...   Lee, Minyi; Eng, George; Barbari, Stephanie R; Deshpande, Vikram; Shcherbakova, Polina V; Gala, ... R01ES015869 Clin Transl Gastroenterol (2020 03) 32352724 Exiting the NIEHS site 2020 
Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cance ...   Tsutakawa, Susan E; Sarker, Altaf H; Ng, Clifford; Arvai, Andrew S; Shin, David S; Shih, Brian ... R01ES031635 Proc Natl Acad Sci U S A (2020 06 23) 32522879 Exiting the NIEHS site 2020 
Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can ...   Sviderskiy, Vladislav O; Blumenberg, Lili; Gorodetsky, Elizabeth; Karakousi, Triantafyllia R; Hi ... R01ES025166 Mol Cell (2020 11 19) 33152268 Exiting the NIEHS site 2020 
Hypoxia Induces Resistance to EGFR Inhibitors in Lung Cancer Cells via Upregulation of FGFR1 and the ...   Lu, Yuhong; Liu, Yanfeng; Oeck, Sebastian; Zhang, Gary J; Schramm, Alexander; Glazer, Peter M R01ES005775 Cancer Res (2020 11 01) 32873635 Exiting the NIEHS site 2020 
Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary ...   Clements, Kristen E; Schleicher, Emily M; Thakar, Tanay; Hale, Anastasia; Dhoonmoon, Ashna; Tol ... R01ES026184, R01ES026184 Nat Commun (2020 11 30) 33257658 Exiting the NIEHS site 2020 
Impact of 1,N6-ethenoadenosine, a damaged ribonucleotide in DNA, on translesion synthesis and repair ...   Ghodke, Pratibha P; Guengerich, F Peter R01ES026955 J Biol Chem (2020 05 01) 32213600 Exiting the NIEHS site 2020 
Impact of hypoxia on DNA repair and genome integrity.   Kaplan, Alanna R; Glazer, Peter M R01ES005775 Mutagenesis (2020 02 13) 31282537 Exiting the NIEHS site 2020 
Insights into the Direct Oxidative Repair of Etheno Lesions: MD and QM/MM Study on the Substrate Sco ...   Lenz, Stefan A P; Li, Deyu; Wetmore, Stacey D R01ES028865, R01ES028865, R01ES028865, R01ES028865 DNA Repair (Amst) (2020 12) 33161373 Exiting the NIEHS site 2020 
Intergenerational transmission of childhood trauma? Testing cellular aging in mothers exposed to sex ...   Etzel, Laura; Hastings, Waylon J; Mattern, Brooke C; Oxford, Monica L; Heim, Christine; Putnam, ... U01ES030949 Psychoneuroendocrinology (2020 10) 32629221 Exiting the NIEHS site 2020 
Kinetic investigation of the polymerase and exonuclease activities of human DNA polymerase ε holoenz ...   Zahurancik, Walter J; Suo, Zucai R01ES028271 J Biol Chem (2020 12 11) 33051204 Exiting the NIEHS site 2020 
MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA ...   Huang, Jen-Wei; Acharya, Ananya; Taglialatela, Angelo; Nambiar, Tarun S; Cuella-Martin, Raquel; ... R01ES030335 Nat Commun (2020 06 11) 32528060 Exiting the NIEHS site 2020 
Methodologies for detecting environmentally induced DNA damage and repair.   Li, Wentao; Sancar, Aziz R01ES027255 Environ Mol Mutagen (2020 08) 32083352 Exiting the NIEHS site 2020 
Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading stran ...   Bulock, Chelsea R; Xing, Xuanxuan; Shcherbakova, Polina V R01ES015869 Nucleic Acids Res (2020 09 18) 32756902 Exiting the NIEHS site 2020 
Mitochondrial dysfunction and DNA damage accompany enhanced levels of formaldehyde in cultured prima ...   Nadalutti, Cristina A; Stefanick, Donna F; Zhao, Ming-Lang; Horton, Julie K; Prasad, Rajendra; ... R01ES031635 Sci Rep (2020 03 27) 32221313 Exiting the NIEHS site 2020 
Molecular and structural characterization of disease-associated APE1 polymorphisms.   Whitaker, Amy M; Stark, Wesley J; Flynn, Tony S; Freudenthal, Bret D R01ES029203 DNA Repair (Amst) (2020 Jul - Aug) 32454397 Exiting the NIEHS site 2020 
Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair.   Tam, Lok Ming; Price, Nathan E; Wang, Yinsheng R01ES029749, T32ES018827 Chem Res Toxicol (2020 03 16) 31986875 Exiting the NIEHS site 2020 
Monogenic and polygenic inheritance become instruments for clonal selection.   Loh, Po-Ru; Genovese, Giulio; McCarroll, Steven A DP2ES030554 Nature (2020 08) 32581363 Exiting the NIEHS site 2020 
Mutagenesis mechanism of the major oxidative adenine lesion 7,8-dihydro-8-oxoadenine.   Koag, Myong-Chul; Jung, Hunmin; Lee, Seongmin R01ES026676 Nucleic Acids Res (2020 05 21) 32282906 Exiting the NIEHS site 2020 
N6-methyladenine in DNA antagonizes SATB1 in early development.   Li, Zheng; Zhao, Shuai; Nelakanti, Raman V; Lin, Kaixuan; Wu, Tao P; Alderman 3rd, Myles H; Gu ... R35ES031707 Nature (2020 07) 32669713 Exiting the NIEHS site 2020 
NAD+-mediated regulation of mammalian base excision repair.   Saville, Kate M; Clark, Jennifer; Wilk, Anna; Rogers, Gresyn D; Andrews, Joel F; Koczor, Chris ... P01ES028949, R01ES014811, U01ES029518, U01ES029518 DNA Repair (Amst) (2020 09) 33087267 Exiting the NIEHS site 2020 
New insights into abasic site repair and tolerance.   Thompson, Petria S; Cortez, David R01ES030575 DNA Repair (Amst) (2020 06) 32417669 Exiting the NIEHS site 2020 
New insights into the regulation of DNA-Protein Crosslink Repair by the Aspartic Protease Ddi1 in ye ...   El Dika, Mohammed R01ES030575 DNA Repair (Amst) (2020 06) 32330640 Exiting the NIEHS site 2020 
Normalized retention time for scheduled liquid chromatography-multistage mass spectrometry analysis ...   Gonzalez, Gwendolyn; Cui, Yuxiang; Wang, Pengcheng; Wang, Yinsheng R35ES031707, T32ES018827 J Chromatogr A (2020 Jul 19) 32505282 Exiting the NIEHS site 2020 
Nuclear and Cytoplasmic Functions of Vitamin C.   Zhitkovich, Anatoly R01ES028072, R01ES028072, R01ES031002, R01ES031002 Chem Res Toxicol (2020 10 19) 33001635 Exiting the NIEHS site 2020 
Oncometabolites suppress DNA repair by disrupting local chromatin signalling.   Sulkowski, Parker L; Oeck, Sebastian; Dow, Jonathan; Economos, Nicholas G; Mirfakhraie, Lily; L ... R01ES005775 Nature (2020 06) 32494005 Exiting the NIEHS site 2020 
Pathogenic Mechanisms of Somatic Mutation and Genome Mosaicism in Aging.   Vijg, Jan; Dong, Xiao U01ES029519 Cell (2020 07 09) 32649873 Exiting the NIEHS site 2020 
Pharmacological methods to transcriptionally modulate double-strand break DNA repair.   Kaplan, Alanna R; Glazer, Peter M R01ES005775 Int Rev Cell Mol Biol (2020) 32475473 Exiting the NIEHS site 2020 
Pol β gap filling, DNA ligation and substrate-product channeling during base excision repair opposit ...   Çağlayan, Melike R00ES026191 DNA Repair (Amst) (2020 11) 32853828 Exiting the NIEHS site 2020 
Pol μ ribonucleotide insertion opposite 8-oxodG facilitates the ligation of premutagenic DNA repair ...   Çağlayan, Melike R00ES026191 Sci Rep (2020 01 22) 31969622 Exiting the NIEHS site 2020 
POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair S ...   Hodel, Karl P; Sun, Meijuan J S; Ungerleider, Nathan; Park, Vivian S; Williams, Leonard G; Baue ... R01ES028271 Mol Cell (2020 06 18) 32497495 Exiting the NIEHS site 2020 
Promutagenic bypass of 7,8-dihydro-8-oxoadenine by translesion synthesis DNA polymerase Dpo4.   Jung, Hunmin; Lee, Seongmin R01ES026676 Biochem J (2020 08 14) 32686822 Exiting the NIEHS site 2020 
Proteome-wide Interrogation of Small GTPases Regulated by N6-Methyladenosine Modulators.   Yang, Yen-Yu; Yu, Kailin; Li, Lin; Huang, Ming; Wang, Yinsheng R35ES031707, T32ES018827 Anal Chem (2020 07 21) 32567849 Exiting the NIEHS site 2020 
RAD51 Gene Family Structure and Function.   Bonilla, Braulio; Hengel, Sarah R; Grundy, McKenzie K; Bernstein, Kara A R01ES030335 Annu Rev Genet (2020 11 23) 32663049 Exiting the NIEHS site 2020 
Rad54 and Rdh54 occupy spatially and functionally distinct sites within the Rad51-ssDNA presynaptic ...   Crickard, J Brooks; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 EMBO J (2020 10 15) 32790929 Exiting the NIEHS site 2020 
Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination.   Crickard, J Brooks; Moevus, Corentin J; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Cell (2020 06 11) 32502392 Exiting the NIEHS site 2020 
Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1.   Minko, Irina G; Vartanian, Vladimir L; Tozaki, Naoto N; Coskun, Erdem; Coskun, Sanem Hosbas; Ja ... R01ES031086 DNA Repair (Amst) (2020 01) 31733589 Exiting the NIEHS site 2020 
Regulation and pharmacological targeting of RAD51 in cancer.   Grundy, McKenzie K; Buckanovich, Ronald J; Bernstein, Kara A R01ES030335 NAR Cancer (2020 Sep) 33015624 Exiting the NIEHS site 2020 
REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallma ...   Chatterjee, Nimrat; Whitman, Matthew A; Harris, Cynthia A; Min, Sophia M; Jonas, Oliver; Lien, ... P30ES002109, R35ES028303 Proc Natl Acad Sci U S A (2020 11 17) 33168727 Exiting the NIEHS site 2020 
Rev7 loss alters cisplatin response and increases drug efficacy in chemotherapy-resistant lung cance ...   Vassel, Faye-Marie; Bian, Ke; Walker, Graham C; Hemann, Michael T P30ES002109, R35ES028303, T32ES007020 Proc Natl Acad Sci U S A (2020 11 17) 33144509 Exiting the NIEHS site 2020 
Roles for MDC1 in cancer development and treatment.   Ruff, Sophie E; Logan, Susan K; Garabedian, Michael J; Huang, Tony T R01ES025166 DNA Repair (Amst) (2020 11) 32866776 Exiting the NIEHS site 2020 
Single-molecule live-cell imaging reveals RecB-dependent function of DNA polymerase IV in double str ...   Henrikus, Sarah S; Henry, Camille; McGrath, Amy E; Jergic, Slobodan; McDonald, John P; Hellmich ... R35ES028343 Nucleic Acids Res (2020 09 04) 32687193 Exiting the NIEHS site 2020 
Specificity of end resection pathways for double-strand break regions containing ribonucleotides and ...   Daley, James M; Tomimatsu, Nozomi; Hooks, Grace; Wang, Weibin; Miller, Adam S; Xue, Xiaoyu; Ng ... R01ES007061 Nat Commun (2020 06 18) 32555206 Exiting the NIEHS site 2020 
Structural basis for STAT2 suppression by flavivirus NS5.   Wang, Boxiao; Thurmond, Stephanie; Zhou, Kang; Sánchez-Aparicio, Maria T; Fang, Jian; Lu, Jiuw ... R35ES031707 Nat Struct Mol Biol (2020 10) 32778820 Exiting the NIEHS site 2020 
Structural biology of DNA abasic site protection by SRAP proteins.   Amidon, Katherine M; Eichman, Brandt F F31ES032334, R01ES030575 DNA Repair (Amst) (2020 10) 32663791 Exiting the NIEHS site 2020 
Structural insights into the bypass of the major deaminated purines by translesion synthesis DNA pol ...   Jung, Hunmin; Hawkins, Michael; Lee, Seongmin R01ES026676 Biochem J (2020 12) 33258913 Exiting the NIEHS site 2020 
Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion.   Ouzon-Shubeita, Hala; Vilas, Caroline K; Lee, Seongmin R01ES026676 Biochem J (2020 03 13) 32039434 Exiting the NIEHS site 2020 
Tethering-facilitated DNA 'opening' and complementary roles of β-hairpin motifs in the Rad4/XPC DNA ...   Paul, Debamita; Mu, Hong; Tavakoli, Amirrasoul; Dai, Qing; Chen, Xuejing; Chakraborty, Sagnik; ... R01ES025987 Nucleic Acids Res (2020 12 02) 33119737 Exiting the NIEHS site 2020 
The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication.   Tarsounas, Madalena; Sung, Patrick R01ES007061 Nat Rev Mol Cell Biol (2020 05) 32094664 Exiting the NIEHS site 2020 
The circadian clock shapes the Arabidopsis transcriptome by regulating alternative splicing and alte ...   Yang, Yuchen; Li, Yun; Sancar, Aziz; Oztas, Onur R01ES027255 J Biol Chem (2020 05 29) 32303634 Exiting the NIEHS site 2020 
The DNA damage-sensing NER repair factor XPC-RAD23B does not recognize bulky DNA lesions with a miss ...   Feher, Katie M; Kolbanovskiy, Alexander; Durandin, Alexander; Shim, Yoonjung; Min, Jung-Hyun; L ... R01ES025987 DNA Repair (Amst) (2020 12) 33035795 Exiting the NIEHS site 2020 
The DNA-binding activity of USP1-associated factor 1 is required for efficient RAD51-mediated homolo ...   Liang, Fengshan; Miller, Adam S; Tang, Caroline; Maranon, David; Williamson, Elizabeth A; Hroma ... R01ES007061 J Biol Chem (2020 06 12) 32350107 Exiting the NIEHS site 2020 
The involvement of nucleotide excision repair proteins in the removal of oxidative DNA damage.   Kumar, Namrata; Raja, Sripriya; Van Houten, Bennett R35ES031638 Nucleic Acids Res (2020 11 18) 33010169 Exiting the NIEHS site 2020 
The ligation of pol β mismatch insertion products governs the formation of promutagenic base excisio ...   Çağlayan, Melike R00ES026191 Nucleic Acids Res (2020 04 17) 32140717 Exiting the NIEHS site 2020 
The roles of polymerases ν and θ in replicative bypass of O 6- and N 2-alkyl-2'-deoxyguanosine lesio ...   Du, Hua; Wang, Pengcheng; Wu, Jun; He, Xiaomei; Wang, Yinsheng R01ES029749 J Biol Chem (2020 04 03) 32098870 Exiting the NIEHS site 2020 
Translesion synthesis of 6-nitrochrysene-derived 2'-deoxyadenosine adduct in human cells.   Powell, Brent V; Bacurio, Jan Henric T; Basu, Ashis K R01ES023350 DNA Repair (Amst) (2020 11) 32721818 Exiting the NIEHS site 2020 
Translesion synthesis of the major nitrogen mustard-induced DNA lesion by human DNA polymerase η.   Jung, Hunmin; Rayala, Naveen Kumar; Lee, Seongmin R01ES026676 Biochem J (2020 12 11) 33175093 Exiting the NIEHS site 2020 
Tumor-Targeted, Cytoplasmic Delivery of Large, Polar Molecules Using a pH-Low Insertion Peptide.   Svoronos, Alexander A; Bahal, Raman; Pereira, Mohan C; Barrera, Francisco N; Deacon, John C; Bo ... R01ES005775 Mol Pharm (2020 02 03) 31855437 Exiting the NIEHS site 2020 
Twenty years of t-loops: A case study for the importance of collaboration in molecular biology.   Tomáška, Ľubomír; Cesare, Anthony J; AlTurki, Taghreed M; Griffith, Jack D R01ES031635 DNA Repair (Amst) (2020 10) 32620538 Exiting the NIEHS site 2020 
Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki f ...   Thakar, Tanay; Leung, Wendy; Nicolae, Claudia M; Clements, Kristen E; Shen, Binghui; Bielinsky, ... R01ES026184, R01ES026184 Nat Commun (2020 05 01) 32358495 Exiting the NIEHS site 2020 
Unhooking of an interstrand cross-link at DNA fork structures by the DNA glycosylase NEIL3.   Imani Nejad, Maryam; Housh, Kurt; Rodriguez, Alyssa A; Haldar, Tuhin; Kathe, Scott; Wallace, S ... R01ES021007, R01ES021007 DNA Repair (Amst) (2020 02) 31923807 Exiting the NIEHS site 2020 
Uninterruptible Power Supply Improves Precision and External Validity of Telomere Length Measurement ...   Hastings, Waylon J; Eisenberg, Dan T A; Shalev, Idan U01ES030949 Exp Results (2020) 33718773 Exiting the NIEHS site 2020 
Variable impact of conformationally distinct DNA lesions on nucleosome structure and dynamics: Impli ...   Cai, Yuqin; Geacintov, Nicholas E; Broyde, Suse R01ES025987 DNA Repair (Amst) (2020 03) 32018112 Exiting the NIEHS site 2020 
VEZF1-guanine quadruplex DNA interaction regulates alternative polyadenylation and detyrosinase acti ...   Li, Lin; Williams, Preston; Gao, Zi; Wang, Yinsheng R35ES031707 Nucleic Acids Res (2020 12 02) 33231681 Exiting the NIEHS site 2020 
5-Formylcytosine-induced DNA-peptide cross-links reduce transcription efficiency, but do not cause t ...   Ji, Shaofei; Park, Daeyoon; Kropachev, Konstantin; Kolbanovskiy, Marina; Fu, Iwen; Broyde, Sus ... R01ES023350, R01ES025987 J Biol Chem (2019 11 29) 31597704 Exiting the NIEHS site 2019 
A parametric meta-analysis.   Yu, Chang; Zelterman, Daniel R01ES005775 Stat Med (2019 09 20) 31206759 Exiting the NIEHS site 2019 
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme.   Xing, Xuanxuan; Kane, Daniel P; Bulock, Chelsea R; Moore, Elizabeth A; Sharma, Sushma; Chabes, ... R01ES015869 Nat Commun (2019 01 22) 30670691 Exiting the NIEHS site 2019 
A Small Molecule Targeting Mutagenic Translesion Synthesis Improves Chemotherapy.   Wojtaszek, Jessica L; Chatterjee, Nimrat; Najeeb, Javaria; Ramos, Azucena; Lee, Minhee; Bian, ... R01ES028865, R01ES028865, R01ES028865, R01ES028865, R35ES028303 Cell (2019 06 27) 31178121 Exiting the NIEHS site 2019 
A two-stage phase II clinical trial design with nested criteria for early stopping and efficacy.   DeVeaux, Michelle; Kane, Michael; Wei, Wei; Zelterman, Daniel R01ES005775 Pharm Stat (2019 11) 31507079 Exiting the NIEHS site 2019 
A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action.   Yang, Jason H; Wright, Sarah N; Hamblin, Meagan; McCloskey, Douglas; Alcantar, Miguel A; Schrüb ... R35ES028303 Cell (2019 05 30) 31080069 Exiting the NIEHS site 2019 
Aberrant Activation of β-Catenin Signaling Drives Glioma Tumorigenesis via USP1-Mediated Stabilizati ...   Ma, Li; Lin, Kangyu; Chang, Guoqiang; Chen, Yiwen; Yue, Chen; Guo, Qing; Zhang, Sicong; Jia, ... R01ES025166 Cancer Res (2019 01 01) 30425057 Exiting the NIEHS site 2019 
Accelerating cancer without mutations.   Brash, Douglas E R01ES030562 Elife (2019 03 21) 30895924 Exiting the NIEHS site 2019 
Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo a ...   Coskun, Erdem; Jaruga, Pawel; Vartanian, Vladimir; Erdem, Onur; Egner, Patricia A; Groopman, J ... R01ES031086 Chem Res Toxicol (2019 01 22) 30525498 Exiting the NIEHS site 2019 
AID-RNA polymerase II transcription-dependent deamination of IgV DNA.   Pham, Phuong; Malik, Sohail; Mak, Chiho; Calabrese, Peter C; Roeder, Robert G; Goodman, Myron ... R35ES028343 Nucleic Acids Res (2019 11 18) 31566237 Exiting the NIEHS site 2019 
Bioactivation of the tobacco carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole ...   Bellamri, Medjda; Yao, Lihua; Bonala, Radha; Johnson, Francis; Von Weymarn, Linda B; Turesky, ... R01ES019564, R01ES030559 Arch Toxicol (2019 07) 31203411 Exiting the NIEHS site 2019 
Biological Evaluation of DNA Biomarkers in a Chemically Defined and Site-Specific Manner.   Bian, Ke; Delaney, James C; Zhou, Xianhao; Li, Deyu R01ES028865, R01ES028865, R01ES028865, R01ES028865 Toxics (2019 Jun 25) 31242562 Exiting the NIEHS site 2019 
Bypass of the Major Alkylative DNA Lesion by Human DNA Polymerase η.   Koag, Myong-Chul; Jung, Hunmin; Kou, Yi; Lee, Seongmin R01ES026676 Molecules (2019 Oct 31) 31683505 Exiting the NIEHS site 2019 
Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51.   Kaplan, Alanna R; Gueble, Susan E; Liu, Yanfeng; Oeck, Sebastian; Kim, Hoon; Yun, Zhong; Glaze ... R01ES005775 Sci Transl Med (2019 05 15) 31092693 Exiting the NIEHS site 2019 
Conformational regulation of Escherichia coli DNA polymerase V by RecA and ATP.   Jaszczur, Malgorzata M; Vo, Dan D; Stanciauskas, Ramunas; Bertram, Jeffrey G; Sikand, Adhirath; ... R35ES028343 PLoS Genet (2019 02) 30716079 Exiting the NIEHS site 2019 
Ddc2ATRIP promotes Mec1ATR activation at RPA-ssDNA tracts.   Biswas, Himadri; Goto, Greicy; Wang, Weibin; Sung, Patrick; Sugimoto, Katsunori R01ES007061 PLoS Genet (2019 08) 31369547 Exiting the NIEHS site 2019 
Defining the influence of Rad51 and Dmc1 lineage-specific amino acids on genetic recombination.   Steinfeld, Justin B; Beláň, Ondrej; Kwon, Youngho; Terakawa, Tsuyoshi; Al-Zain, Amr; Smith, Mi ... R01ES007061 Genes Dev (2019 09 01) 31371435 Exiting the NIEHS site 2019 
Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse org ...   Yimit, Askar; Adebali, Ogun; Sancar, Aziz; Jiang, Yuchao P30ES010126, R01ES027255 Nat Commun (2019 01 18) 30659176 Exiting the NIEHS site 2019 
DNA Crosslinkomics: A Tool for the Comprehensive Assessment of Interstrand Crosslinks Using High Res ...   Hu, Chiung-Wen; Chang, Yuan-Jhe; Cooke, Marcus S; Chao, Mu-Rong R01ES030557 Anal Chem (2019 12 03) 31670503 Exiting the NIEHS site 2019 
DNA methylation modifications induced by hexavalent chromium.   Guo, Xinnian; Feng, Lingfang; Lemos, Bernardo; Lou, Jianlin R01ES027981 J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2019) 31084241 Exiting the NIEHS site 2019 
DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-f ...   Bian, Ke; Lenz, Stefan A P; Tang, Qi; Chen, Fangyi; Qi, Rui; Jost, Marco; Drennan, Catherine ... P30ES002109, R01ES028865, R01ES028865, R01ES028865, R01ES028865 Nucleic Acids Res (2019 06 20) 31114894 Exiting the NIEHS site 2019 
DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage re ...   Liang, Fengshan; Miller, Adam S; Longerich, Simonne; Tang, Caroline; Maranon, David; Williamson ... R01ES007061 Nat Commun (2019 06 28) 31253762 Exiting the NIEHS site 2019 
Drosophila, which lacks canonical transcription-coupled repair proteins, performs transcription-coup ...   Deger, Nazli; Yang, Yanyan; Lindsey-Boltz, Laura A; Sancar, Aziz; Selby, Christopher P R01ES027255 J Biol Chem (2019 11 29) 31624146 Exiting the NIEHS site 2019 
Dynamic interactions of the homologous pairing 2 (Hop2)-meiotic nuclear divisions 1 (Mnd1) protein c ...   Crickard, J Brooks; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 J Biol Chem (2019 01 11) 30420424 Exiting the NIEHS site 2019 
Error-prone replication of a 5-formylcytosine-mediated DNA-peptide cross-link in human cells.   Naldiga, Spandana; Ji, Shaofei; Thomforde, Jenna; Nicolae, Claudia M; Lee, Marietta; Zhang, Zh ... R01ES023350, R01ES026184, R01ES026184 J Biol Chem (2019 07 05) 31138652 Exiting the NIEHS site 2019 
Exposure to an environmentally relevant phthalate mixture during prostate development induces microR ...   Scarano, Wellerson R; Bedrat, Amina; Alonso-Costa, Luiz G; Aquino, Ariana M; Fantinatti, Bruno; ... R01ES027981 Toxicol Sci (2019 Jun 14) 31199487 Exiting the NIEHS site 2019 
Genetic predisposition to mosaic Y chromosome loss in blood.   Thompson, Deborah J; Genovese, Giulio; Halvardson, Jonatan; Ulirsch, Jacob C; Wright, Daniel J; ... DP2ES030554 Nature (2019 11) 31748747 Exiting the NIEHS site 2019 
Genome-wide mapping of nucleotide excision repair with XR-seq.   Hu, Jinchuan; Li, Wentao; Adebali, Ogun; Yang, Yanyan; Oztas, Onur; Selby, Christopher P; Sanc ... P30ES010126, R01ES027255 Nat Protoc (2019 01) 30552409 Exiting the NIEHS site 2019 
Genomic sites hypersensitive to ultraviolet radiation.   Premi, Sanjay; Han, Lynn; Mehta, Sameet; Knight, James; Zhao, Dejian; Palmatier, Meg A; Kornac ... R01ES030562 Proc Natl Acad Sci U S A (2019 11 26) 31723047 Exiting the NIEHS site 2019 
Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes.   Klein, Hannah L; Ang, Kenny K H; Arkin, Michelle R; Beckwitt, Emily C; Chang, Yi-Hsuan; Fan, J ... R01ES007061 Microb Cell (2019 Jan 07) 30652106 Exiting the NIEHS site 2019 
GWAS of mosaic loss of chromosome Y highlights genetic effects on blood cell differentiation.   Terao, Chikashi; Momozawa, Yukihide; Ishigaki, Kazuyoshi; Kawakami, Eiryo; Akiyama, Masato; Loh ... DP2ES030554 Nat Commun (2019 10 17) 31624269 Exiting the NIEHS site 2019 
High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation.   Oeck, Sebastian; Malewicz, Nathalie M; Krysztofiak, Adam; Turchick, Audrey; Jendrossek, Verena; ... R01ES005775 Sci Rep (2019 02 28) 30816253 Exiting the NIEHS site 2019 
Human DNA polymerase η has reverse transcriptase activity in cellular environments.   Su, Yan; Ghodke, Pratibha P; Egli, Martin; Li, Lin; Wang, Yinsheng; Guengerich, F Peter R01ES026955 J Biol Chem (2019 04 12) 30842261 Exiting the NIEHS site 2019 
Hydrolyzable Tannins Are Iron Chelators That Inhibit DNA Repair Enzyme ALKBH2.   Chen, Fangyi; Tang, Qi; Ma, Hang; Bian, Ke; Seeram, Navindra P; Li, Deyu R01ES028865, R01ES028865, R01ES028865, R01ES028865 Chem Res Toxicol (2019 06 17) 31088072 Exiting the NIEHS site 2019 
Interplay between DNA Polymerases and DNA Ligases: Influence on Substrate Channeling and the Fidelit ...   Çağlayan, Melike R00ES026191 J Mol Biol (2019 05 17) 31034893 Exiting the NIEHS site 2019 
Interstrand DNA Cross-Links Derived from Reaction of a 2-Aminopurine Residue with an Abasic Site.   Nejad, Maryam Imani; Price, Nathan E; Haldar, Tuhin; Lewis, Calvin; Wang, Yinsheng; Gates, Ken ... R01ES021007, R01ES021007, T32ES018827 ACS Chem Biol (2019 07 19) 31259519 Exiting the NIEHS site 2019 
Long-term, genome-wide kinetic analysis of the effect of the circadian clock and transcription on th ...   Yang, Yanyan; Liu, Zhenxing; Selby, Christopher P; Sancar, Aziz P30ES010126, R01ES027255 J Biol Chem (2019 08 09) 31217280 Exiting the NIEHS site 2019 
Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleo ...   Rai, Priyamvada; Sobol, Robert W P01ES028949, R01ES014811, U01ES029518, U01ES029518 DNA Repair (Amst) (2019 05) 30852368 Exiting the NIEHS site 2019 
Mechanistic Study of TTF-1 Modulation of Cellular Sensitivity to Cisplatin.   Phelps, Cody A; Lindsey-Boltz, Laura; Sancar, Aziz; Mu, David P30ES010126, R01ES027255 Sci Rep (2019 05 29) 31142791 Exiting the NIEHS site 2019 
MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers.   Srinivasan, Gayathri; Williamson, Elizabeth A; Kong, Kimi; Jaiswal, Aruna S; Huang, Guangcun; K ... R01ES007061 Proc Natl Acad Sci U S A (2019 08 27) 31395736 Exiting the NIEHS site 2019 
Mitochondrial DNA: Epigenetics and environment.   Sharma, Nidhi; Pasala, Monica S; Prakash, Aishwarya R01ES030084, R01ES030084 Environ Mol Mutagen (2019 10) 31335990 Exiting the NIEHS site 2019 
Murine models of accelerated aging and musculoskeletal disease.   Hambright, William S; Niedernhofer, Laura J; Huard, Johnny; Robbins, Paul D U01ES029603 Bone (2019 08) 30844492 Exiting the NIEHS site 2019 
Mutagenic Replication of the Major Oxidative Adenine Lesion 7,8-Dihydro-8-oxoadenine by Human DNA Po ...   Koag, Myong-Chul; Jung, Hunmin; Lee, Seongmin R01ES026676 J Am Chem Soc (2019 03 20) 30817143 Exiting the NIEHS site 2019 
N-Acetylcysteine: Antioxidant, Aldehyde Scavenger, and More.   Zhitkovich, Anatoly R01ES028072, R01ES028072 Chem Res Toxicol (2019 07 15) 31046246 Exiting the NIEHS site 2019 
NuA4 acetyltransferase is required for efficient nucleotide excision repair in yeast.   Hodges, Amelia J; Plummer, Dalton A; Wyrick, John J R01ES028698 DNA Repair (Amst) (2019 01) 30473425 Exiting the NIEHS site 2019 
Nucleotide Excision Repair and Impact of Site-Specific 5',8-Cyclopurine and Bulky DNA Lesions on the ...   Shafirovich, Vladimir; Kolbanovskiy, Marina; Kropachev, Konstantin; Liu, Zhi; Cai, Yuquin; Terz ... R01ES025987 Biochemistry (2019 02 12) 30570250 Exiting the NIEHS site 2019 
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma ce ...   Li, Wentao; Liu, Wenjie; Kakoki, Ayano; Wang, Rujin; Adebali, Ogun; Jiang, Yuchao; Sancar, Az ... P30ES010126, R01ES027255 J Biol Chem (2019 04 12) 30808711 Exiting the NIEHS site 2019 
Organization of DNA damage, excision repair, and mutagenesis in chromatin: A genomic perspective.   Mao, Peng; Wyrick, John J R01ES028698 DNA Repair (Amst) (2019 09) 31307926 Exiting the NIEHS site 2019 
Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selec ...   Zhu, Haizhou; Mishra, Rosalin; Yuan, Long; Abdul Salam, Safnas F; Liu, Jing; Gray, George; Ste ... R15ES029675, R15ES029675 ChemMedChem (2019 11 20) 31696673 Exiting the NIEHS site 2019 
p53 activation by Cr(VI): a transcriptionally limited response induced by ATR kinase in S-phase.   Luczak, Michal W; Krawic, Casey; Zhitkovich, Anatoly R01ES028072, R01ES028072 Toxicol Sci (2019 Aug 06) 31388677 Exiting the NIEHS site 2019 
POLE proofreading defects: Contributions to mutagenesis and cancer.   Park, Vivian S; Pursell, Zachary F R01ES028271 DNA Repair (Amst) (2019 04) 30818169 Exiting the NIEHS site 2019 
Preparation and Purification of Oligodeoxynucleotide Duplexes Containing a Site-Specific, Reduced, C ...   Nejad, Maryam Imani; Guo, Xu; Housh, Kurt; Nel, Christopher; Yang, Zhiyu; Price, Nathan E; Wan ... R01ES021007, R01ES021007 Methods Mol Biol (2019) 31016701 Exiting the NIEHS site 2019 
Probing the Effect of Bulky Lesion-Induced Replication Fork Conformational Heterogeneity Using 4-Ami ...   Cai, Ang; Bian, Ke; Chen, Fangyi; Tang, Qi; Carley, Rachel; Li, Deyu; Cho, Bongsup P R01ES028865, R01ES028865, R01ES028865, R01ES028865 Molecules (2019 Apr 20) 31009995 Exiting the NIEHS site 2019 
Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion.   Kou, Yi; Koag, Myong-Chul; Lee, Seongmin R01ES026676 Molecules (2019 Sep 27) 31569643 Exiting the NIEHS site 2019 
Protection of abasic sites during DNA replication by a stable thiazolidine protein-DNA cross-link.   Thompson, Petria S; Amidon, Katherine M; Mohni, Kareem N; Cortez, David; Eichman, Brandt F R01ES030575 Nat Struct Mol Biol (2019 07) 31235915 Exiting the NIEHS site 2019 
R-loop formation by dCas9 is mutagenic in Saccharomyces cerevisiae.   Laughery, Marian F; Mayes, Hannah C; Pedroza, Ivan K; Wyrick, John J R01ES028698 Nucleic Acids Res (2019 03 18) 30590793 Exiting the NIEHS site 2019 
Rad52 Restrains Resection at DNA Double-Strand Break Ends in Yeast.   Yan, Zhenxin; Xue, Chaoyou; Kumar, Sandeep; Crickard, J Brooks; Yu, Yang; Wang, Weibin; Pham, ... R01ES007061 Mol Cell (2019 12 05) 31542296 Exiting the NIEHS site 2019 
Random Walk Enzymes: Information Theory, Quantum Isomorphism, and Entropy Dispersion.   Mak, Chi H; Pham, Phuong; Goodman, Myron F R35ES028343 J Phys Chem A (2019 Apr 04) 30848911 Exiting the NIEHS site 2019 
Recurrent Noncoding Mutations in Skin Cancers: UV Damage Susceptibility or Repair Inhibition as Prim ...   Roberts, Steven A; Brown, Alexander J; Wyrick, John J R01ES028698 Bioessays (2019 03) 30801747 Exiting the NIEHS site 2019 
Regulatory control of Sgs1 and Dna2 during eukaryotic DNA end resection.   Xue, Chaoyou; Wang, Weibin; Crickard, J Brooks; Moevus, Corentin J; Kwon, Youngho; Sung, Patri ... R01ES007061 Proc Natl Acad Sci U S A (2019 03 26) 30850524 Exiting the NIEHS site 2019 
Replication-Coupled DNA Repair.   Cortez, David R01ES030575 Mol Cell (2019 06 06) 31173722 Exiting the NIEHS site 2019 
Ribosomal DNA and the Nucleolus as Keystones of Nuclear Architecture, Organization, and Function.   Cerqueira, Amanda V; Lemos, Bernardo R01ES027981 Trends Genet (2019 10) 31447250 Exiting the NIEHS site 2019 
Ribosomal DNA harbors an evolutionarily conserved clock of biological aging.   Wang, Meng; Lemos, Bernardo P30ES000002, R01ES027981 Genome Res (2019 03) 30765617 Exiting the NIEHS site 2019 
Role of RNase H enzymes in maintaining genome stability in Escherichia coli expressing a steric-gate ...   Walsh, Erin; Henrikus, Sarah S; Vaisman, Alexandra; Makiela-Dzbenska, Karolina; Armstrong, Thom ... R35ES028343 DNA Repair (Amst) (2019 12) 31543434 Exiting the NIEHS site 2019 
Role of Y-family translesion DNA polymerases in replication stress: Implications for new cancer ther ...   Tonzi, Peter; Huang, Tony T R01ES025166 DNA Repair (Amst) (2019 06) 30954011 Exiting the NIEHS site 2019 
Rotational and translational positions determine the structural and dynamic impact of a single ribon ...   Fu, Iwen; Smith, Duncan J; Broyde, Suse R01ES025987 DNA Repair (Amst) (2019 01) 30522887 Exiting the NIEHS site 2019 
Sense and sensibility: ATM oxygen stress signaling manages brain cell energetics.   Schlacher, Katharina R01ES029680, R01ES029680 J Cell Biol (2019 03 04) 30782782 Exiting the NIEHS site 2019 
Simple CRISPR-Cas9 Genome Editing in Saccharomyces cerevisiae.   Laughery, Marian F; Wyrick, John J R01ES028698 Curr Protoc Mol Biol (2019 12) 31763795 Exiting the NIEHS site 2019 
Single-molecule visualization of human BLM helicase as it acts upon double- and single-stranded DNA ...   Xue, Chaoyou; Daley, James M; Xue, Xiaoyu; Steinfeld, Justin; Kwon, Youngho; Sung, Patrick; Gr ... R01ES007061 Nucleic Acids Res (2019 12 02) 31544923 Exiting the NIEHS site 2019 
Single-nucleotide resolution analysis of nucleotide excision repair of ribosomal DNA in humans and m ...   Yang, Yanyan; Hu, Jinchuan; Selby, Christopher P; Li, Wentao; Yimit, Askar; Jiang, Yuchao; San ... P30ES010126, R01ES027255 J Biol Chem (2019 01 04) 30413533 Exiting the NIEHS site 2019 
Structural basis for the bypass of the major oxaliplatin-DNA adducts by human DNA polymerase η.   Ouzon-Shubeita, Hala; Baker, Meghan; Koag, Myong-Chul; Lee, Seongmin R01ES026676 Biochem J (2019 02 28) 30709915 Exiting the NIEHS site 2019 
Structural consequence of the most frequently recurring cancer-associated substitution in DNA polyme ...   Parkash, Vimal; Kulkarni, Yashraj; Ter Beek, Josy; Shcherbakova, Polina V; Kamerlin, Shina Caro ... R01ES015869 Nat Commun (2019 01 22) 30670696 Exiting the NIEHS site 2019 
Structure and mechanism of pyrimidine-pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucl ...   Paul, Debamita; Mu, Hong; Zhao, Hong; Ouerfelli, Ouathek; Jeffrey, Philip D; Broyde, Suse; Min ... R01ES025987 Nucleic Acids Res (2019 07 09) 31106376 Exiting the NIEHS site 2019 
Synthesis and Characterization of Site-Specific O6 -Alkylguanine DNA-Alkyl Transferase-Oligonucleoti ...   Ghodke, Pratibha P; Albertolle, Matthew E; Johnson, Kevin M; Guengerich, F Peter R01ES026955, T32ES007028 Curr Protoc Nucleic Acid Chem (2019 03) 30657645 Exiting the NIEHS site 2019 
Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis.   Fouquerel, Elise; Barnes, Ryan P; Uttam, Shikhar; Watkins, Simon C; Bruchez, Marcel P; Opresko, ... R00ES027028 Mol Cell (2019 07 11) 31101499 Exiting the NIEHS site 2019 
Targeting phosphatases in cancer: suppression of many versus the ablation of one.   D'Arcy, Brandon M; Prakash, Aishwarya; Honkanen, Richard E R01ES030084, R01ES030084 Oncotarget (2019 Nov 12) 31762936 Exiting the NIEHS site 2019 
The BRCA Tumor Suppressor Network in Chromosome Damage Repair by Homologous Recombination.   Zhao, Weixing; Wiese, Claudia; Kwon, Youngho; Hromas, Robert; Sung, Patrick R01ES007061 Annu Rev Biochem (2019 06 20) 30917004 Exiting the NIEHS site 2019 
The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway.   Rosenbaum, Joel C; Bonilla, Braulio; Hengel, Sarah R; Mertz, Tony M; Herken, Benjamin W; Kazemi ... R01ES007061 Nat Commun (2019 08 05) 31383866 Exiting the NIEHS site 2019 
The RecQ helicase Sgs1 drives ATP-dependent disruption of Rad51 filaments.   Crickard, J Brooks; Xue, Chaoyou; Wang, Weibin; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Nucleic Acids Res (2019 05 21) 30916344 Exiting the NIEHS site 2019 
Transcription shapes DNA replication initiation and termination in human cells.   Chen, Yu-Hung; Keegan, Sarah; Kahli, Malik; Tonzi, Peter; Fenyö, David; Huang, Tony T; Smith, ... R01ES025166 Nat Struct Mol Biol (2019 01) 30598550 Exiting the NIEHS site 2019 
Transcriptional Bypass of DNA-Protein and DNA-Peptide Conjugates by T7 RNA Polymerase.   Ji, Shaofei; Thomforde, Jenna; Rogers, Colette; Fu, Iwen; Broyde, Suse; Tretyakova, Natalia Y R01ES023350, R01ES025987 ACS Chem Biol (2019 12 20) 31573793 Exiting the NIEHS site 2019 
Virtual Pharmacophore Screening Identifies Small-Molecule Inhibitors of the Rev1-CT/RIR Protein-Prot ...   Dash, Radha C; Ozen, Zuleyha; McCarthy, Kaitlyn R; Chatterjee, Nimrat; Harris, Cynthia A; Rizzo ... P30ES002109, R35ES028303 ChemMedChem (2019 09 04) 31361935 Exiting the NIEHS site 2019 
Vitamin C increases DNA breaks and suppresses DNA damage-independent activation of ATM by bleomycin.   Rubis, Blazej; Luczak, Michal W; Krawic, Casey; Zhitkovich, Anatoly R01ES028072, R01ES028072 Free Radic Biol Med (2019 05 20) 30926564 Exiting the NIEHS site 2019 
5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce mutations in huma ...   Ji, Shaofei; Fu, Iwen; Naldiga, Spandana; Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... R01ES023350, R01ES025987 Nucleic Acids Res (2018 07 27) 29905846 Exiting the NIEHS site 2018 
A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) o ...   Wang, Weibin; Daley, James M; Kwon, Youngho; Xue, Xiaoyu; Krasner, Danielle S; Miller, Adam S; ... R01ES007061 J Biol Chem (2018 11 02) 30224356 Exiting the NIEHS site 2018 
A new mitotic activity comes into focus.   Saldivar, Joshua C; Cimprich, Karlene A R01ES016486, R01ES016486 Science (2018 01 05) 29302000 Exiting the NIEHS site 2018 
A quantitative PCR-based assay reveals that nucleotide excision repair plays a predominant role in t ...   Chesner, Lisa N; Campbell, Colin R01ES023350 DNA Repair (Amst) (2018 02) 29413806 Exiting the NIEHS site 2018 
A Simple, Rapid, and Quantitative Assay to Measure Repair of DNA-protein Crosslinks on Plasmids Tran ...   Chesner, Lisa N; Campbell, Colin R01ES023350 J Vis Exp (2018 03 05) 29553515 Exiting the NIEHS site 2018 
An intrinsic S/G2 checkpoint enforced by ATR.   Saldivar, Joshua C; Hamperl, Stephan; Bocek, Michael J; Chung, Mingyu; Bass, Thomas E; Cisneros ... R01ES016486, R01ES016486 Science (2018 08 24) 30139873 Exiting the NIEHS site 2018 
Cisplatin-DNA adduct repair of transcribed genes is controlled by two circadian programs in mouse ti ...   Yang, Yanyan; Adebali, Ogun; Wu, Gang; Selby, Christopher P; Chiou, Yi-Ying; Rashid, Naim; Hu, ... P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2018 05 22) 29735688 Exiting the NIEHS site 2018 
Comparative properties and functions of type 2 and type 4 pigeon cryptochromes.   Wang, Xuefeng; Jing, Chengyu; Selby, Christopher P; Chiou, Yi-Ying; Yang, Yanyan; Wu, Wenjian; ... R01ES027255 Cell Mol Life Sci (2018 Dec) 30264181 Exiting the NIEHS site 2018 
Corrigendum: 5-Formylcytosine mediated DNA-protein cross-links block DNA replication and induce muta ...   Ji, Shaofei; Fu, Iwen; Naldiga, Spandana; Shao, Hongzhao; Basu, Ashis K; Broyde, Suse; Tretyak ... R01ES025987 Nucleic Acids Res (2018 10 12) 30184121 Exiting the NIEHS site 2018 
DNA Damage, Mutagenesis and Cancer.   Basu, Ashis K R01ES023350 Int J Mol Sci (2018 Mar 23) 29570697 Exiting the NIEHS site 2018 
Electron-Mediated Aminyl and Iminyl Radicals from C5 Azido-Modified Pyrimidine Nucleosides Augment R ...   Wen, Zhiwei; Peng, Jufang; Tuttle, Paloma R; Ren, Yaou; Garcia, Carol; Debnath, Dipra; Rishi, ... R01ES005775 Org Lett (2018 12 07) 30457873 Exiting the NIEHS site 2018 
Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributio ...   Chakraborty, Sagnik; Steinbach, Peter J; Paul, Debamita; Mu, Hong; Broyde, Suse; Min, Jung-Hyu ... R01ES025987 Nucleic Acids Res (2018 02 16) 29267981 Exiting the NIEHS site 2018 
Evidence that microplastics aggravate the toxicity of organophosphorus flame retardants in mice (Mus ...   Deng, Yongfeng; Zhang, Yan; Qiao, Ruxia; Bonilla, Melvin M; Yang, Xiaoliang; Ren, Hongqiang; L ... R01ES027981 J Hazard Mater (2018 09 05) 29908513 Exiting the NIEHS site 2018 
Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is dri ...   Hodel, Karl P; de Borja, Richard; Henninger, Erin E; Campbell, Brittany B; Ungerleider, Nathan; ... R01ES028271 Elife (2018 02 28) 29488881 Exiting the NIEHS site 2018 
Functional Analysis of Cancer-Associated DNA Polymerase ε Variants in Saccharomyces cerevisiae.   Barbari, Stephanie R; Kane, Daniel P; Moore, Elizabeth A; Shcherbakova, Polina V R01ES015869 G3 (Bethesda) (2018 03 02) 29352080 Exiting the NIEHS site 2018 
Genome-wide excision repair in Arabidopsis is coupled to transcription and reflects circadian gene e ...   Oztas, Onur; Selby, Christopher P; Sancar, Aziz; Adebali, Ogun P30ES010126, R01ES027255 Nat Commun (2018 04 17) 29666379 Exiting the NIEHS site 2018 
Histone tails decrease N7-methyl-2'-deoxyguanosine depurination and yield DNA-protein cross-links in ...   Yang, Kun; Park, Daeyoon; Tretyakova, Natalia Y; Greenberg, Marc M R01ES023350 Proc Natl Acad Sci U S A (2018 11 27) 30429328 Exiting the NIEHS site 2018 
Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and ...   Lu, Yuhong; Liu, Yanfeng; Oeck, Sebastian; Glazer, Peter M R01ES005775 Mol Cancer Res (2018 10) 29934325 Exiting the NIEHS site 2018 
Importance of homo-dimerization of Fanconi-associated nuclease 1 in DNA flap cleavage.   Rao, Timsi; Longerich, Simonne; Zhao, Weixing; Aihara, Hideki; Sung, Patrick; Xiong, Yong R01ES007061 DNA Repair (Amst) (2018 04) 29518739 Exiting the NIEHS site 2018 
In a Class of Its Own: A New Family of Deubiquitinases Promotes Genome Stability.   Coleman, Kate E; Huang, Tony T R01ES025166 Mol Cell (2018 04 05) 29625031 Exiting the NIEHS site 2018 
Incomplete base excision repair contributes to cell death from antibiotics and other stresses.   Gruber, Charley C; Walker, Graham C R35ES028303 DNA Repair (Amst) (2018 11) 30181041 Exiting the NIEHS site 2018 
Insights into the effect of minor groove interactions and metal cofactors on mutagenic replication b ...   Koag, Myong-Chul; Lee, Seongmin R01ES026676 Biochem J (2018 02 09) 29301983 Exiting the NIEHS site 2018 
Introduction to the Thematic Minireview Series: DNA double-strand break repair and pathway choice.   Sung, Patrick R01ES007061 J Biol Chem (2018 07 06) 29853635 Exiting the NIEHS site 2018 
Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination ...   Sulkowski, Parker L; Sundaram, Ranjini K; Oeck, Sebastian; Corso, Christopher D; Liu, Yanfeng; ... R01ES005775 Nat Genet (2018 08) 30013182 Exiting the NIEHS site 2018 
Lesion Sensing during Initial Binding by Yeast XPC/Rad4: Toward Predicting Resistance to Nucleotide ...   Mu, Hong; Zhang, Yingkai; Geacintov, Nicholas E; Broyde, Suse R01ES025987 Chem Res Toxicol (2018 11 19) 30284444 Exiting the NIEHS site 2018 
Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient c ...   Clements, Kristen E; Thakar, Tanay; Nicolae, Claudia M; Liang, Xinwen; Wang, Hong-Gang; Moldova ... R01ES026184, R01ES026184 Nucleic Acids Res (2018 09 28) 30032296 Exiting the NIEHS site 2018 
Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase.   Crickard, J Brooks; Kaniecki, Kyle; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Proc Natl Acad Sci U S A (2018 10 23) 30301803 Exiting the NIEHS site 2018 
Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excisi ...   Mu, Hong; Geacintov, Nicholas E; Broyde, Suse; Yeo, Jung-Eun; Schärer, Orlando D R01ES025987 DNA Repair (Amst) (2018 11) 30174301 Exiting the NIEHS site 2018 
Monoubiquitinated γ-H2AX: Abundant product and specific biomarker for non-apoptotic DNA double-stran ...   Luczak, Michal W; Zhitkovich, Anatoly R01ES028072, R01ES028072 Toxicol Appl Pharmacol (2018 09 15) 30006243 Exiting the NIEHS site 2018 
Normalized Retention Time for Targeted Analysis of the DNA Adductome.   Cui, Yuxiang; Wang, Pengcheng; Yu, Yang; Yuan, Jun; Wang, Yinsheng R01ES029749 Anal Chem (2018 12 18) 30500177 Exiting the NIEHS site 2018 
Nucleosome positions establish an extended mutation signature in melanoma.   Brown, Alexander J; Mao, Peng; Smerdon, Michael J; Wyrick, John J; Roberts, Steven A R01ES028698 PLoS Genet (2018 11) 30485262 Exiting the NIEHS site 2018 
PARP10 promotes cellular proliferation and tumorigenesis by alleviating replication stress.   Schleicher, Emily M; Galvan, Adri M; Imamura-Kawasawa, Yuka; Moldovan, George-Lucian; Nicolae, ... R01ES026184, R01ES026184 Nucleic Acids Res (2018 09 28) 30032250 Exiting the NIEHS site 2018 
Pol μ dGTP mismatch insertion opposite T coupled with ligation reveals promutagenic DNA repair inter ...   Çağlayan, Melike; Wilson, Samuel H R00ES026191 Nat Commun (2018 10 11) 30310068 Exiting the NIEHS site 2018 
PTEN Regulates Nonhomologous End Joining By Epigenetic Induction of NHEJ1/XLF.   Sulkowski, Parker L; Scanlon, Susan E; Oeck, Sebastian; Glazer, Peter M R01ES005775 Mol Cancer Res (2018 08) 29739874 Exiting the NIEHS site 2018 
Regulation of Hed1 and Rad54 binding during maturation of the meiosis-specific presynaptic complex.   Crickard, J Brooks; Kaniecki, Kyle; Kwon, YoungHo; Sung, Patrick; Lisby, Michael; Greene, Eric ... R01ES007061 EMBO J (2018 04 03) 29444896 Exiting the NIEHS site 2018 
Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis comp ...   Rizzo, Alessandro A; Vassel, Faye-Marie; Chatterjee, Nimrat; D'Souza, Sanjay; Li, Yunfeng; Hao, ... P30ES002109, R35ES028303 Proc Natl Acad Sci U S A (2018 08 28) 30111544 Exiting the NIEHS site 2018 
RNA polymerase II is released from the DNA template during transcription-coupled repair in mammalian ...   Chiou, Yi-Ying; Hu, Jinchuan; Sancar, Aziz; Selby, Christopher P R01ES027255 J Biol Chem (2018 02 16) 29282293 Exiting the NIEHS site 2018 
Single-nucleotide resolution dynamic repair maps of UV damage in Saccharomyces cerevisiae genome.   Li, Wentao; Adebali, Ogun; Yang, Yanyan; Selby, Christopher P; Sancar, Aziz P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2018 04 10) 29581276 Exiting the NIEHS site 2018 
Site-specific cross-linking of proteins to DNA via a new bioorthogonal approach employing oxime liga ...   Pujari, Suresh S; Zhang, Yi; Ji, Shaofei; Distefano, Mark D; Tretyakova, Natalia Y R01ES023350 Chem Commun (Camb) (2018 Jun 14) 29851420 Exiting the NIEHS site 2018 
Smoking gun for a rare mutation mechanism.   Goodman, Myron F R35ES028343 Nature (2018 02 08) 29420502 Exiting the NIEHS site 2018 
Spontaneous self-segregation of Rad51 and Dmc1 DNA recombinases within mixed recombinase filaments.   Crickard, J Brooks; Kaniecki, Kyle; Kwon, YoungHo; Sung, Patrick; Greene, Eric C R01ES007061 J Biol Chem (2018 03 16) 29382724 Exiting the NIEHS site 2018 
Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dyn ...   Daigh, Leighton H; Liu, Chad; Chung, Mingyu; Cimprich, Karlene A; Meyer, Tobias R01ES016486, R01ES016486 Cell Syst (2018 07 25) 29909278 Exiting the NIEHS site 2018 
Structural and Kinetic Studies of the Effect of Guanine N7 Alkylation and Metal Cofactors on DNA Rep ...   Kou, Yi; Koag, Myong-Chul; Lee, Seongmin R01ES026676 Biochemistry (2018 08 28) 29957995 Exiting the NIEHS site 2018 
Suppression of homology-dependent DNA double-strand break repair induces PARP inhibitor sensitivity ...   Scanlon, Susan E; Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M R01ES005775 Oncotarget (2018 Jan 12) 29435132 Exiting the NIEHS site 2018 
Synergistic effects of H3 and H4 nucleosome tails on structure and dynamics of a lesion-containing D ...   Cai, Yuqin; Fu, Iwen; Geacintov, Nicholas E; Zhang, Yingkai; Broyde, Suse R01ES025987 DNA Repair (Amst) (2018 05) 29631253 Exiting the NIEHS site 2018 
The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase acti ...   Suisse, Annabelle; Békés, Miklós; Huang, Tony T; Treisman, Jessica E R01ES025166 Fly (Austin) (2018) 29355077 Exiting the NIEHS site 2018 
The hypoxic tumor microenvironment in vivo selects the cancer stem cell fate of breast cancer cells.   Kim, Hoon; Lin, Qun; Glazer, Peter M; Yun, Zhong R01ES005775 Breast Cancer Res (2018 03 06) 29510720 Exiting the NIEHS site 2018 
The long-range interaction map of ribosomal DNA arrays.   Yu, Shoukai; Lemos, Bernardo R01ES027981 PLoS Genet (2018 03) 29570716 Exiting the NIEHS site 2018 
Toxicological Antagonism among Welding Fume Metals: Inactivation of Soluble Cr(VI) by Iron.   Krawic, Casey; Zhitkovich, Anatoly R01ES028072, R01ES028072 Chem Res Toxicol (2018 11 19) 30362728 Exiting the NIEHS site 2018 
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery.   Tonzi, Peter; Yin, Yandong; Lee, Chelsea Wei Ting; Rothenberg, Eli; Huang, Tony T R01ES025166 Elife (2018 11 13) 30422114 Exiting the NIEHS site 2018 
Urinary DNA adductomics - A novel approach for exposomics.   Cooke, Marcus S; Hu, Chiung-Wen; Chang, Yuan-Jhe; Chao, Mu-Rong R01ES030557 Environ Int (2018 12) 30392940 Exiting the NIEHS site 2018 
What is the potential of nanolock- and nanocross-nanopore technology in cancer diagnosis?   Gu, Li-Qun; Gates, Kent S; Wang, Michael X; Li, Guangfu R01ES021007, R01ES021007 Expert Rev Mol Diagn (2018 02) 29171309 Exiting the NIEHS site 2018 
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and indu ...   Sulkowski, Parker L; Corso, Christopher D; Robinson, Nathaniel D; Scanlon, Susan E; Purshouse, ... R01ES005775 Sci Transl Med (2017 02 01) 28148839 Exiting the NIEHS site 2017 
A novel role of the Dna2 translocase function in DNA break resection.   Miller, Adam S; Daley, James M; Pham, Nhung Tuyet; Niu, Hengyao; Xue, Xiaoyu; Ira, Grzegorz; S ... R01ES007061 Genes Dev (2017 03 01) 28336516 Exiting the NIEHS site 2017 
A parametric model to estimate the proportion from true null using a distribution for p-values.   Yu, Chang; Zelterman, Daniel R01ES005775 Comput Stat Data Anal (2017 Oct) 28827889 Exiting the NIEHS site 2017 
A role for the base excision repair enzyme NEIL3 in replication-dependent repair of interstrand DNA ...   Yang, Zhiyu; Nejad, Maryam Imani; Varela, Jacqueline Gamboa; Price, Nathan E; Wang, Yinsheng; G ... R01ES021007, R01ES021007, T32ES018827 DNA Repair (Amst) (2017 04) 28262582 Exiting the NIEHS site 2017 
Anti-tumor Activity of miniPEG-γ-Modified PNAs to Inhibit MicroRNA-210 for Cancer Therapy.   Gupta, Anisha; Quijano, Elias; Liu, Yanfeng; Bahal, Raman; Scanlon, Susan E; Song, Eric; Hsieh ... R01ES005775 Mol Ther Nucleic Acids (2017 Dec 15) 29246289 Exiting the NIEHS site 2017 
BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.   Zhao, Weixing; Steinfeld, Justin B; Liang, Fengshan; Chen, Xiaoyong; Maranon, David G; Jian Ma, ... R01ES007061 Nature (2017 10 19) 28976962 Exiting the NIEHS site 2017 
Cellular Repair of DNA-DNA Cross-Links Induced by 1,2,3,4-Diepoxybutane.   Chesner, Lisa N; Degner, Amanda; Sangaraju, Dewakar; Yomtoubian, Shira; Wickramaratne, Susith; ... R01ES023350 Int J Mol Sci (2017 May 18) 28524082 Exiting the NIEHS site 2017 
Chemical Biology of N5-Substituted Formamidopyrimidine DNA Adducts.   Pujari, Suresh S; Tretyakova, Natalia R01ES023350 Chem Res Toxicol (2017 01 17) 27959490 Exiting the NIEHS site 2017 
Comprehensive Analysis of Hypermutation in Human Cancer.   Campbell, Brittany B; Light, Nicholas; Fabrizio, David; Zatzman, Matthew; Fuligni, Fabio; de Bo ... R01ES028271 Cell (2017 Nov 16) 29056344 Exiting the NIEHS site 2017 
Controlling the Graphene-Bio Interface: Dispersions in Animal Sera for Enhanced Stability and Reduce ...   Pattammattel, Ajith; Pande, Paritosh; Kuttappan, Deepa; Puglia, Megan; Basu, Ashis K; Amalaradj ... R01ES023350 Langmuir (2017 12 12) 29144756 Exiting the NIEHS site 2017 
Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange.   Xu, Jingfei; Zhao, Lingyun; Xu, Yuanyuan; Zhao, Weixing; Sung, Patrick; Wang, Hong-Wei R01ES007061 Nat Struct Mol Biol (2017 01) 27941862 Exiting the NIEHS site 2017 
Detection of the Excised, Damage-containing Oligonucleotide Products of Nucleotide Excision Repair i ...   Song, Jimyeong; Kemp, Michael G; Choi, Jun-Hyuk R01ES027255 Photochem Photobiol (2017 01) 27634428 Exiting the NIEHS site 2017 
Dissociation of Rad51 Presynaptic Complexes and Heteroduplex DNA Joints by Tandem Assemblies of Srs2 ...   Kaniecki, Kyle; De Tullio, Luisina; Gibb, Bryan; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 Cell Rep (2017 Dec 12) 29241544 Exiting the NIEHS site 2017 
Dynamic maps of UV damage formation and repair for the human genome.   Hu, Jinchuan; Adebali, Ogun; Adar, Sheera; Sancar, Aziz P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2017 06 27) 28607063 Exiting the NIEHS site 2017 
Enhancement of BLM-DNA2-Mediated Long-Range DNA End Resection by CtIP.   Daley, James M; Jimenez-Sainz, Judit; Wang, Weibin; Miller, Adam S; Xue, Xiaoyu; Nguyen, Kevin ... R01ES007061 Cell Rep (2017 Oct 10) 29020620 Exiting the NIEHS site 2017 
Forging Ahead through Darkness: PCNA, Still the Principal Conductor at the Replication Fork.   Choe, Katherine N; Moldovan, George-Lucian R01ES026184, R01ES026184 Mol Cell (2017 Feb 02) 28157503 Exiting the NIEHS site 2017 
Genome-wide transcription-coupled repair in Escherichia coli is mediated by the Mfd translocase.   Adebali, Ogun; Chiou, Yi-Ying; Hu, Jinchuan; Sancar, Aziz; Selby, Christopher P R01ES027255 Proc Natl Acad Sci U S A (2017 03 14) 28167766 Exiting the NIEHS site 2017 
Human DNA polymerase η accommodates RNA for strand extension.   Su, Yan; Egli, Martin; Guengerich, F Peter R01ES026955 J Biol Chem (2017 11 03) 28972162 Exiting the NIEHS site 2017 
Human genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyrene.   Li, Wentao; Hu, Jinchuan; Adebali, Ogun; Adar, Sheera; Yang, Yanyan; Chiou, Yi-Ying; Sancar, ... P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2017 06 27) 28607059 Exiting the NIEHS site 2017 
Human RAD52 interactions with replication protein A and the RAD51 presynaptic complex.   Ma, Chu Jian; Kwon, Youngho; Sung, Patrick; Greene, Eric C R01ES007061 J Biol Chem (2017 07 14) 28551686 Exiting the NIEHS site 2017 
Mass Spectrometry Based Proteomics Study of Cisplatin-Induced DNA-Protein Cross-Linking in Human Fib ...   Ming, Xun; Groehler 4th, Arnold; Michaelson-Richie, Erin D; Villalta, Peter W; Campbell, Colin; ... R01ES023350 Chem Res Toxicol (2017 04 17) 28282121 Exiting the NIEHS site 2017 
Mass Spectrometry-Based Tools to Characterize DNA-Protein Cross-Linking by Bis-Electrophiles.   Groehler 4th, Arnold; Degner, Amanda; Tretyakova, Natalia Y R01ES023350 Basic Clin Pharmacol Toxicol (2017 Sep) 28032943 Exiting the NIEHS site 2017 
Mfd Protein and Transcription-Repair Coupling in Escherichia coli.   Selby, Christopher P R01ES027255 Photochem Photobiol (2017 01) 27864884 Exiting the NIEHS site 2017 
Mfd translocase is necessary and sufficient for transcription-coupled repair in Escherichia coli.   Adebali, Ogun; Sancar, Aziz; Selby, Christopher P R01ES027255 J Biol Chem (2017 11 10) 28986449 Exiting the NIEHS site 2017 
Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans.   Hu, Jinchuan; Selby, Christopher P; Adar, Sheera; Adebali, Ogun; Sancar, Aziz P30ES010126, R01ES027255 J Biol Chem (2017 09 22) 28798238 Exiting the NIEHS site 2017 
Mutagenicity of a Model DNA-Peptide Cross-Link in Human Cells: Roles of Translesion Synthesis DNA Po ...   Pande, Paritosh; Ji, Shaofei; Mukherjee, Shivam; Schärer, Orlando D; Tretyakova, Natalia Y; Bas ... R01ES023350 Chem Res Toxicol (2017 Feb 20) 27951635 Exiting the NIEHS site 2017 
Nanoarmoring: strategies for preparation of multi-catalytic enzyme polymer conjugates and enhancemen ...   Zore, Omkar V; Pande, Paritosh; Okifo, Oghenenyerovwo; Basu, Ashis K; Kasi, Rajeswari M; Kumar, ... R01ES023350 RSC Adv (2017) 29403641 Exiting the NIEHS site 2017 
Nickel induces transcriptional down-regulation of DNA repair pathways in tumorigenic and non-tumorig ...   Scanlon, Susan E; Scanlon, Christine D; Hegan, Denise C; Sulkowski, Parker L; Glazer, Peter M R01ES005775 Carcinogenesis (2017 06 01) 28472268 Exiting the NIEHS site 2017 
Nucleosome Histone Tail Conformation and Dynamics: Impacts of Lysine Acetylation and a Nearby Minor ...   Fu, Iwen; Cai, Yuqin; Geacintov, Nicholas E; Zhang, Yingkai; Broyde, Suse R01ES025987 Biochemistry (2017 04 11) 28304160 Exiting the NIEHS site 2017 
Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA D ...   Adkins, Nicholas L; Swygert, Sarah G; Kaur, Parminder; Niu, Hengyao; Grigoryev, Sergei A; Sung, ... P30ES025128, R01ES007061 J Biol Chem (2017 Mar 31) 28202543 Exiting the NIEHS site 2017 
Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a ...   Mu, Hong; Geacintov, Nicholas E; Min, Jung-Hyun; Zhang, Yingkai; Broyde, Suse R01ES025987 Chem Res Toxicol (2017 06 19) 28460163 Exiting the NIEHS site 2017 
Nucleotide selectivity defect and mutator phenotype conferred by a colon cancer-associated DNA polym ...   Mertz, T M; Baranovskiy, A G; Wang, J; Tahirov, T H; Shcherbakova, P V R01ES015869 Oncogene (2017 Aug) 28368425 Exiting the NIEHS site 2017 
PARPi focus the spotlight on replication fork protection in cancer.   Schlacher, Katharina R01ES029680, R01ES029680 Nat Cell Biol (2017 Oct 31) 29087384 Exiting the NIEHS site 2017 
Plasticity of the Mre11-Rad50-Xrs2-Sae2 nuclease ensemble in the processing of DNA-bound obstacles.   Wang, Weibin; Daley, James M; Kwon, Youngho; Krasner, Danielle S; Sung, Patrick R01ES007061 Genes Dev (2017 12 01) 29321177 Exiting the NIEHS site 2017 
PostExcision Events in Human Nucleotide Excision Repair.   Kemp, Michael G; Hu, Jinchuan R01ES027255 Photochem Photobiol (2017 01) 27645806 Exiting the NIEHS site 2017 
Repair-Resistant DNA Lesions.   Geacintov, Nicholas E; Broyde, Suse R01ES025987 Chem Res Toxicol (2017 08 21) 28750166 Exiting the NIEHS site 2017 
Replicative DNA polymerase defects in human cancers: Consequences, mechanisms, and implications for ...   Barbari, Stephanie R; Shcherbakova, Polina V R01ES015869 DNA Repair (Amst) (2017 08) 28687338 Exiting the NIEHS site 2017 
Reversible DNA-Protein Cross-Linking at Epigenetic DNA Marks.   Ji, Shaofei; Shao, Hongzhao; Han, Qiyuan; Seiler, Christopher L; Tretyakova, Natalia Y R01ES023350 Angew Chem Int Ed Engl (2017 11 06) 28898504 Exiting the NIEHS site 2017 
Ribosomal DNA copy number amplification and loss in human cancers is linked to tumor genetic context ...   Wang, Meng; Lemos, Bernardo R01ES027981 PLoS Genet (2017 Sep) 28880866 Exiting the NIEHS site 2017 
Role of DNA polymerase β oxidized nucleotide insertion in DNA ligation failure.   Çaglayan, Melike; Wilson, Samuel H R00ES026191 J Radiat Res (2017 Sep 01) 28992331 Exiting the NIEHS site 2017 
Role of the Pif1-PCNA Complex in Pol δ-Dependent Strand Displacement DNA Synthesis and Break-Induced ...   Buzovetsky, Olga; Kwon, Youngho; Pham, Nhung Tuyet; Kim, Claire; Ira, Grzegorz; Sung, Patrick; ... R01ES007061 Cell Rep (2017 Nov 14) 29141206 Exiting the NIEHS site 2017 
SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligas ...   Coleman, Kate E; Békés, Miklós; Chapman, Jessica R; Crist, Sarah B; Jones, Mathew Jk; Ueberheid ... R01ES025166 Elife (2017 05 05) 28475037 Exiting the NIEHS site 2017 
Sequence imperfections and base triplet recognition by the Rad51/RecA family of recombinases.   Lee, Ja Yil; Steinfeld, Justin B; Qi, Zhi; Kwon, YoungHo; Sung, Patrick; Greene, Eric C R01ES007061 J Biol Chem (2017 06 30) 28476890 Exiting the NIEHS site 2017 
Sequence-Specific Covalent Capture Coupled with High-Contrast Nanopore Detection of a Disease-Derive ...   Nejad, Maryam Imani; Shi, Ruicheng; Zhang, Xinyue; Gu, Li-Qun; Gates, Kent S R01ES021007, R01ES021007 Chembiochem (2017 07 18) 28422400 Exiting the NIEHS site 2017 
The Cartography of UV-induced DNA Damage Formation and DNA Repair.   Hu, Jinchuan; Adar, Sheera R01ES027255 Photochem Photobiol (2017 01) 27861959 Exiting the NIEHS site 2017 
The essential kinase ATR: ensuring faithful duplication of a challenging genome.   Saldivar, Joshua C; Cortez, David; Cimprich, Karlene A R01ES016486, R01ES016486 Nat Rev Mol Cell Biol (2017 10) 28811666 Exiting the NIEHS site 2017 
The Nonbulky DNA Lesions Spiroiminodihydantoin and 5-Guanidinohydantoin Significantly Block Human RN ...   Kolbanovskiy, Marina; Chowdhury, Moinuddin A; Nadkarni, Aditi; Broyde, Suse; Geacintov, Nichola ... R01ES025987 Biochemistry (2017 06 20) 28514164 Exiting the NIEHS site 2017 
Translesion Synthesis of 2'-Deoxyguanosine Lesions by Eukaryotic DNA Polymerases.   Basu, Ashis K; Pande, Paritosh; Bose, Arindam R01ES021762, R01ES023350 Chem Res Toxicol (2017 01 17) 27760288 Exiting the NIEHS site 2017 
Ultrathin Graphene-Protein Supercapacitors for Miniaturized Bioelectronics.   Mosa, Islam M; Pattammattel, Ajith; Kadimisetty, Karteek; Pande, Paritosh; El-Kady, Maher F; Bi ... R01ES023350 Adv Energy Mater (2017 Sep 06) 29104523 Exiting the NIEHS site 2017 
Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiol ...   Kochenova, Olga V; Bezalel-Buch, Rachel; Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... R01ES015869 Nucleic Acids Res (2017 02 17) 28180291 Exiting the NIEHS site 2017 
Yeast Srs2 Helicase Promotes Redistribution of Single-Stranded DNA-Bound RPA and Rad52 in Homologous ...   De Tullio, Luisina; Kaniecki, Kyle; Kwon, Youngho; Crickard, J Brooks; Sung, Patrick; Greene, ... R01ES007061 Cell Rep (2017 Oct 17) 29045827 Exiting the NIEHS site 2017 
Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Sy ...   Wickramaratne, Susith; Ji, Shaofei; Mukherjee, Shivam; Su, Yan; Pence, Matthew G; Lior-Hoffmann ... R01ES023350, R01ES025987 J Biol Chem (2016 Nov 04) 27621316 Exiting the NIEHS site 2016 
Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution.   Hu, Jinchuan; Lieb, Jason D; Sancar, Aziz; Adar, Sheera P30ES010126, R01ES027255 Proc Natl Acad Sci U S A (2016 10 11) 27688757 Exiting the NIEHS site 2016 
Comparative Error-Free and Error-Prone Translesion Synthesis of N(2)-2'-Deoxyguanosine Adducts Forme ...   Bose, Arindam; Surugihalli, Chaitra; Pande, Paritosh; Champeil, Elise; Basu, Ashis K R01ES023350 Chem Res Toxicol (2016 05 16) 27082015 Exiting the NIEHS site 2016 
Covalent DNA-Protein Cross-Linking by Phosphoramide Mustard and Nornitrogen Mustard in Human Cells.   Groehler 4th, Arnold; Villalta, Peter W; Campbell, Colin; Tretyakova, Natalia R01ES023350 Chem Res Toxicol (2016 Feb 15) 26692166 Exiting the NIEHS site 2016 
Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by ...   Xue, Xiaoyu; Papusha, Alma; Choi, Koyi; Bonner, Jacob N; Kumar, Sandeep; Niu, Hengyao; Kaur, ... R01ES007061 Genes Dev (2016 03 15) 26966246 Exiting the NIEHS site 2016 
Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells.   Hess, Gaelen T; Frésard, Laure; Han, Kyuho; Lee, Cameron H; Li, Amy; Cimprich, Karlene A; Mont ... R01ES016486, R01ES016486 Nat Methods (2016 Dec) 27798611 Exiting the NIEHS site 2016 
Effective molarity in a nucleic acid-controlled reaction.   Catalano, Michael J; Price, Nathan E; Gates, Kent S R01ES021007, R01ES021007 Bioorg Med Chem Lett (2016 06 01) 27117430 Exiting the NIEHS site 2016 
Enrichment of Cdk1-cyclins at DNA double-strand breaks stimulates Fun30 phosphorylation and DNA end ...   Chen, Xuefeng; Niu, Hengyao; Yu, Yang; Wang, Jingjing; Zhu, Shuangyi; Zhou, Jianjie; Papusha, ... R01ES007061 Nucleic Acids Res (2016 Apr 07) 26801641 Exiting the NIEHS site 2016 
How SUMOylation Fine-Tunes the Fanconi Anemia DNA Repair Pathway.   Coleman, Kate E; Huang, Tony T R01ES025166 Front Genet (2016) 27148358 Exiting the NIEHS site 2016 
HUWE1 comes to the rescue at stalled replication forks.   Coleman, Kate E; Huang, Tony T R01ES025166 EMBO Rep (2016 06) 27146074 Exiting the NIEHS site 2016 
HUWE1 interacts with PCNA to alleviate replication stress.   Choe, Katherine N; Nicolae, Claudia M; Constantin, Daniel; Imamura Kawasawa, Yuka; Delgado-Diaz, ... R01ES026184, R01ES026184 EMBO Rep (2016 06) 27146073 Exiting the NIEHS site 2016 
Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1.   Callender, Tracy L; Laureau, Raphaelle; Wan, Lihong; Chen, Xiangyu; Sandhu, Rima; Laljee, Saif ... R01ES007061 PLoS Genet (2016 Aug) 27483004 Exiting the NIEHS site 2016 
miR-155 Overexpression Promotes Genomic Instability by Reducing High-fidelity Polymerase Delta Expre ...   Czochor, Jennifer R; Sulkowski, Parker; Glazer, Peter M R01ES005775 Mol Cancer Res (2016 Apr) 26850462 Exiting the NIEHS site 2016 
PARP10 deficiency manifests by severe developmental delay and DNA repair defect.   Shahrour, Maher Awni; Nicolae, Claudia M; Edvardson, Simon; Ashhab, Motee; Galvan, Adri M; Cons ... R01ES026184, R01ES026184 Neurogenetics (2016 10) 27624574 Exiting the NIEHS site 2016 
Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex.   Liang, Fengshan; Longerich, Simonne; Miller, Adam S; Tang, Caroline; Buzovetsky, Olga; Xiong, ... R01ES007061 Cell Rep (2016 06 07) 27239033 Exiting the NIEHS site 2016 
Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Pap ...   Békés, Miklós; van der Heden van Noort, Gerbrand J; Ekkebus, Reggy; Ovaa, Huib; Huang, Tony T; ... R01ES025166 Mol Cell (2016 05 19) 27203180 Exiting the NIEHS site 2016 
Simple, High-Yield Syntheses of DNA Duplexes Containing Interstrand DNA-DNA Cross-Links Between an N ...   Gamboa Varela, Jacqueline; Gates, Kent S R01ES021007, R01ES021007 Curr Protoc Nucleic Acid Chem (2016 06 01) 27248783 Exiting the NIEHS site 2016 
Tel1 and Rif2 Regulate MRX Functions in End-Tethering and Repair of DNA Double-Strand Breaks.   Cassani, Corinne; Gobbini, Elisa; Wang, Weibin; Niu, Hengyao; Clerici, Michela; Sung, Patrick; ... R01ES007061 PLoS Biol (2016 Feb) 26901759 Exiting the NIEHS site 2016 
Yeast DNA polymerase ζ maintains consistent activity and mutagenicity across a wide range of physiol ...   Kochenova, Olga V; Bezalel-Buch, Rachel; Tran, Phong; Makarova, Alena V; Chabes, Andrei; Burger ... R01ES015869 Nucleic Acids Res (2016 Nov 29) 27903904 Exiting the NIEHS site 2016 
A simple, high-yield synthesis of DNA duplexes containing a covalent, thermally cleavable interstran ...   Gamboa Varela, Jacqueline; Gates, Kent S R01ES021007, R01ES021007 Angew Chem Int Ed Engl (2015 Jun 22) 25967397 Exiting the NIEHS site 2015 
Characterization of Interstrand DNA-DNA Cross-Links Derived from Abasic Sites Using Bacteriophage ϕ2 ...   Yang, Zhiyu; Price, Nathan E; Johnson, Kevin M; Gates, Kent S R01ES021007, R01ES021007 Biochemistry (2015 Jul 14) 26103998 Exiting the NIEHS site 2015 
Characterization of Interstrand DNA-DNA Cross-Links Using the α-Hemolysin Protein Nanopore.   Zhang, Xinyue; Price, Nathan E; Fang, Xi; Yang, Zhiyu; Gu, Li-Qun; Gates, Kent S R01ES021007, R01ES021007 ACS Nano (2015 Dec 22) 26563913 Exiting the NIEHS site 2015 
Chemical and structural characterization of interstrand cross-links formed between abasic sites and ...   Price, Nathan E; Catalano, Michael J; Liu, Shuo; Wang, Yinsheng; Gates, Kent S R01ES021007, R01ES021007 Nucleic Acids Res (2015 Apr 20) 25779045 Exiting the NIEHS site 2015 
Chemical structure and properties of interstrand cross-links formed by reaction of guanine residues ...   Catalano, Michael J; Liu, Shuo; Andersen, Nisana; Yang, Zhiyu; Johnson, Kevin M; Price, Nathan ... R01ES021007, R01ES021007 J Am Chem Soc (2015 Mar 25) 25710271 Exiting the NIEHS site 2015 
Colon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing i ...   Mertz, Tony M; Sharma, Sushma; Chabes, Andrei; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2015 May 12) 25827231 Exiting the NIEHS site 2015 
DNA polymerase ζ-dependent lesion bypass in Saccharomyces cerevisiae is accompanied by error-prone c ...   Kochenova, Olga V; Daee, Danielle L; Mertz, Tony M; Shcherbakova, Polina V R01ES015869 PLoS Genet (2015 Mar) 25826305 Exiting the NIEHS site 2015 
DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndrome.   Slaats, Gisela G; Saldivar, Joshua C; Bacal, Julien; Zeman, Michelle K; Kile, Andrew C; Hynes, ... R01ES016486, R01ES016486 J Clin Invest (2015 Sep) 26301811 Exiting the NIEHS site 2015 
DNA sequence alignment by microhomology sampling during homologous recombination.   Qi, Zhi; Redding, Sy; Lee, Ja Yil; Gibb, Bryan; Kwon, YoungHo; Niu, Hengyao; Gaines, William ... R01ES007061 Cell (2015 Feb 26) 25684365 Exiting the NIEHS site 2015 
DNA-Protein Cross-Links: Formation, Structural Identities, and Biological Outcomes.   Tretyakova, Natalia Y; Groehler 4th, Arnold; Ji, Shaofei R01ES023350 Acc Chem Res (2015 Jun 16) 26032357 Exiting the NIEHS site 2015 
Error-prone translesion synthesis past DNA-peptide cross-links conjugated to the major groove of DNA ...   Wickramaratne, Susith; Boldry, Emily J; Buehler, Charles; Wang, Yen-Chih; Distefano, Mark D; Tr ... R01ES023350 J Biol Chem (2015 Jan 09) 25391658 Exiting the NIEHS site 2015 
Functions and regulation of the multitasking FANCM family of DNA motor proteins.   Xue, Xiaoyu; Sung, Patrick; Zhao, Xiaolan R01ES007061 Genes Dev (2015 Sep 01) 26341555 Exiting the NIEHS site 2015 
HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.   Kile, Andrew C; Chavez, Diana A; Bacal, Julien; Eldirany, Sherif; Korzhnev, Dmitry M; Bezsonova ... R01ES016486, R01ES016486 Mol Cell (2015 Jun 18) 26051180 Exiting the NIEHS site 2015 
LKB1 preserves genome integrity by stimulating BRCA1 expression.   Gupta, Romi; Liu, Alex Y; Glazer, Peter M; Wajapeyee, Narendra R01ES005775 Nucleic Acids Res (2015 Jan) 25488815 Exiting the NIEHS site 2015 
Markov counting models for correlated binary responses.   Crawford, Forrest W; Zelterman, Daniel R01ES005775 Biostatistics (2015 Jul) 25792624 Exiting the NIEHS site 2015 
Mass spectrometry for the assessment of the occurrence and biological consequences of DNA adducts.   Liu, Shuo; Wang, Yinsheng R01ES021007, R01ES021007 Chem Soc Rev (2015 Nov 7) 26204249 Exiting the NIEHS site 2015 
Mechanism of action studies of lomaiviticin A and the monomeric lomaiviticin aglycon. Selective and ...   Colis, Laureen C; Hegan, Denise C; Kaneko, Miho; Glazer, Peter M; Herzon, Seth B R01ES005775 J Am Chem Soc (2015 May 6) 25849366 Exiting the NIEHS site 2015 
MicroRNA silencing for cancer therapy targeted to the tumour microenvironment.   Cheng, Christopher J; Bahal, Raman; Babar, Imran A; Pincus, Zachary; Barrera, Francisco; Liu, ... R01ES005775 Nature (2015 Feb 05) 25409146 Exiting the NIEHS site 2015 
Mimicking Ribosomal Unfolding of RNA Pseudoknot in a Protein Channel.   Zhang, Xinyue; Xu, Xiaojun; Yang, Zhiyu; Burcke, Andrew J; Gates, Kent S; Chen, Shi-Jie; Gu, ... R01ES021007, R01ES021007 J Am Chem Soc (2015 Dec 23) 26595106 Exiting the NIEHS site 2015 
Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment.   Scanlon, Susan E; Glazer, Peter M R01ES005775 DNA Repair (Amst) (2015 Aug) 25956861 Exiting the NIEHS site 2015 
Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.   Zhao, Weixing; Vaithiyalingam, Sivaraja; San Filippo, Joseph; Maranon, David G; Jimenez-Sainz, ... R01ES007061 Mol Cell (2015 Jul 16) 26145171 Exiting the NIEHS site 2015 
Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Ra ...   Gaines, William A; Godin, Stephen K; Kabbinavar, Faiz F; Rao, Timsi; VanDemark, Andrew P; Sung, ... R01ES007061 Nat Commun (2015) 26215801 Exiting the NIEHS site 2015 
Selective modulation of the functions of a conserved DNA motor by a histone fold complex.   Xue, Xiaoyu; Choi, Koyi; Bonner, Jacob N; Szakal, Barnabas; Chen, Yu-Hung; Papusha, Alma; Saro ... R01ES007061 Genes Dev (2015 05 15) 25956905 Exiting the NIEHS site 2015 
Significance of ligand interactions involving Hop2-Mnd1 and the RAD51 and DMC1 recombinases in homol ...   Zhao, Weixing; Sung, Patrick R01ES007061 Nucleic Acids Res (2015 Apr 30) 25820426 Exiting the NIEHS site 2015 
Synthesis of DNA Oligodeoxynucleotides Containing Site-Specific 1,3-Butadiene-Deoxyadenosine Lesions ...   Wickramaratne, Susith; Seiler, Christopher L; Tretyakova, Natalia Y R01ES023350 Curr Protoc Nucleic Acid Chem (2015 Jun 03) 26344227 Exiting the NIEHS site 2015 
Synthetic viability genomic screening defines Sae2 function in DNA repair.   Puddu, Fabio; Oelschlaegel, Tobias; Guerini, Ilaria; Geisler, Nicola J; Niu, Hengyao; Herzog, ... R01ES007061 EMBO J (2015 Jun 03) 25899817 Exiting the NIEHS site 2015 
Tumor suppressor p53 stole the AKT in hypoxia.   Yun, Zhong; Glazer, Peter M R01ES005775 J Clin Invest (2015 Jun) 25961449 Exiting the NIEHS site 2015 
A common cancer-associated DNA polymerase ε mutation causes an exceptionally strong mutator phenotyp ...   Kane, Daniel P; Shcherbakova, Polina V R01ES015869 Cancer Res (2014 Apr 1) 24525744 Exiting the NIEHS site 2014 
Avoidance of ribonucleotide-induced mutations by RNase H2 and Srs2-Exo1 mechanisms.   Potenski, Catherine J; Niu, Hengyao; Sung, Patrick; Klein, Hannah L R01ES007061 Nature (2014 Jul 10) 24896181 Exiting the NIEHS site 2014 
Causes and consequences of replication stress.   Zeman, Michelle K; Cimprich, Karlene A R01ES016486, R01ES016486 Nat Cell Biol (2014 Jan) 24366029 Exiting the NIEHS site 2014 
Concentration-dependent exchange of replication protein A on single-stranded DNA revealed by single- ...   Gibb, Bryan; Ye, Ling F; Gergoudis, Stephanie C; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; G ... R01ES007061 PLoS One (2014) 24498402 Exiting the NIEHS site 2014 
Covalent adduct formation between the antihypertensive drug hydralazine and abasic sites in double- ...   Melton, Douglas; Lewis, Calvin D; Price, Nathan E; Gates, Kent S R01ES021007, R01ES021007 Chem Res Toxicol (2014 Dec 15) 25405892 Exiting the NIEHS site 2014 
DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis.   Zeman, Michelle K; Lin, Jia-Ren; Freire, Raimundo; Cimprich, Karlene A R01ES016486, R01ES016486 J Cell Biol (2014 Jul 21) 25023518 Exiting the NIEHS site 2014 
DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures.   Northam, Matthew R; Moore, Elizabeth A; Mertz, Tony M; Binz, Sara K; Stith, Carrie M; Stepchenk ... R01ES015869 Nucleic Acids Res (2014 Jan) 24049079 Exiting the NIEHS site 2014 
Down-regulation of Rad51 activity during meiosis in yeast prevents competition with Dmc1 for repair ...   Liu, Yan; Gaines, William A; Callender, Tracy; Busygina, Valeria; Oke, Ashwini; Sung, Patrick; ... R01ES007061 PLoS Genet (2014 Jan) 24465215 Exiting the NIEHS site 2014 
Hypoxic stress facilitates acute activation and chronic downregulation of fanconi anemia proteins.   Scanlon, Susan E; Glazer, Peter M R01ES005775 Mol Cancer Res (2014 Jul) 24688021 Exiting the NIEHS site 2014 
Interstrand DNA-DNA cross-link formation between adenine residues and abasic sites in duplex DNA.   Price, Nathan E; Johnson, Kevin M; Wang, Jin; Fekry, Mostafa I; Wang, Yinsheng; Gates, Kent S R01ES021007, R01ES021007 J Am Chem Soc (2014 Mar 5) 24506784 Exiting the NIEHS site 2014 
Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing.   Zhao, Weixing; Saro, Dorina; Hammel, Michal; Kwon, Youngho; Xu, Yuanyuan; Rambo, Robert P; Wil ... R01ES007061 Nucleic Acids Res (2014 Jan) 24150939 Exiting the NIEHS site 2014 
Protein dynamics during presynaptic-complex assembly on individual single-stranded DNA molecules.   Gibb, Bryan; Ye, Ling F; Kwon, YoungHo; Niu, Hengyao; Sung, Patrick; Greene, Eric C R01ES007061 Nat Struct Mol Biol (2014 Oct) 25195049 Exiting the NIEHS site 2014 
Replicative bypass of abasic site in Escherichia coli and human cells: similarities and differences.   Weerasooriya, Savithri; Jasti, Vijay P; Basu, Ashis K R01ES021762, R01ES023350 PLoS One (2014) 25226389 Exiting the NIEHS site 2014 
Restriction of replication fork regression activities by a conserved SMC complex.   Xue, Xiaoyu; Choi, Koyi; Bonner, Jacob N; Chiba, Tamara; Kwon, Youngho; Xu, Yuanyuan; Sanchez, ... R01ES007061 Mol Cell (2014 11 06) 25439736 Exiting the NIEHS site 2014 
Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on t ...   Lu, Yuhong; Wajapeyee, Narendra; Turker, Mitchell S; Glazer, Peter M R01ES005775 Cell Rep (2014 Jul 24) 25043185 Exiting the NIEHS site 2014 
The cytotoxicity of (-)-lomaiviticin A arises from induction of double-strand breaks in DNA.   Colis, Laureen C; Woo, Christina M; Hegan, Denise C; Li, Zhenwu; Glazer, Peter M; Herzon, Seth ... R01ES005775 Nat Chem (2014 Jun) 24848236 Exiting the NIEHS site 2014 
Toward hypoxia-selective DNA-alkylating agents built by grafting nitrogen mustards onto the bioreduc ...   Johnson, Kevin M; Parsons, Zachary D; Barnes, Charles L; Gates, Kent S R01ES021007, R01ES021007 J Org Chem (2014 Aug 15) 25029663 Exiting the NIEHS site 2014 
A quantitative mass spectrometry-based approach for assessing the repair of 8-methoxypsoralen-induce ...   Liu, Shuo; Wang, Yinsheng R01ES021007, R01ES021007 Anal Chem (2013 Jul 16) 23789926 Exiting the NIEHS site 2013 
A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in m ...   Kadyrova, Lyudmila Y; Mertz, Tony M; Zhang, Yu; Northam, Matthew R; Sheng, Ziwei; Lobachev, Ki ... R01ES015869 PLoS Genet (2013 Oct) 24204308 Exiting the NIEHS site 2013 
A role for the MRN complex in ATR activation via TOPBP1 recruitment.   Duursma, Anja M; Driscoll, Robert; Elias, Josh E; Cimprich, Karlene A R01ES016486, R01ES016486 Mol Cell (2013 Apr 11) 23582259 Exiting the NIEHS site 2013 
ATR phosphorylates SMARCAL1 to prevent replication fork collapse.   Couch, Frank B; Bansbach, Carol E; Driscoll, Robert; Luzwick, Jessica W; Glick, Gloria G; Bétou ... R01ES016486, R01ES016486, T32ES007028 Genes Dev (2013 Jul 15) 23873943 Exiting the NIEHS site 2013 
Cognitive function and breast cancer: promise and potential insights from functional brain imaging.   Reuter-Lorenz, Patricia A; Cimprich, Bernadine R01ES016486, R01ES016486 Breast Cancer Res Treat (2013 Jan) 23053652 Exiting the NIEHS site 2013 
Functional attributes of the Saccharomyces cerevisiae meiotic recombinase Dmc1.   Busygina, Valeria; Gaines, William A; Xu, Yuanyuan; Kwon, Youngho; Williams, Gareth J; Lin, Sh ... R01ES007061 DNA Repair (Amst) (2013 Sep) 23769192 Exiting the NIEHS site 2013 
Hypoxia and DNA repair.   Glazer, Peter M; Hegan, Denise C; Lu, Yuhong; Czochor, Jennifer; Scanlon, Susan E R01ES005775 Yale J Biol Med (2013 Dec 13) 24348208 Exiting the NIEHS site 2013 
NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopath ...   Choi, Hyo Jei Claudia; Lin, Jia-Ren; Vannier, Jean-Baptiste; Slaats, Gisela G; Kile, Andrew C; ... R01ES016486, R01ES016486 Mol Cell (2013 Aug 22) 23973373 Exiting the NIEHS site 2013 
Nucleosome dynamics regulates DNA processing.   Adkins, Nicholas L; Niu, Hengyao; Sung, Patrick; Peterson, Craig L R01ES007061 Nat Struct Mol Biol (2013 Jul) 23728291 Exiting the NIEHS site 2013 
On the formation and properties of interstrand DNA-DNA cross-links forged by reaction of an abasic s ...   Johnson, Kevin M; Price, Nathan E; Wang, Jin; Fekry, Mostafa I; Dutta, Sanjay; Seiner, Derrick ... R01ES021007, R01ES021007 J Am Chem Soc (2013 Jan 23) 23215239 Exiting the NIEHS site 2013 
PHD domain from human SHPRH.   Machado, Luciana E F; Pustovalova, Yulia; Kile, Andrew C; Pozhidaeva, Alexandra; Cimprich, Karl ... R01ES016486, R01ES016486 J Biomol NMR (2013 Aug) 23907177 Exiting the NIEHS site 2013 
Pif1 helicase and Polýý promote recombination-coupled DNA synthesis via bubble migration.   Wilson, Marenda A; Kwon, YoungHo; Xu, Yuanyuan; Chung, Woo-Hyun; Chi, Peter; Niu, Hengyao; May ... R01ES007061 Nature (2013 Oct 17) 24025768 Exiting the NIEHS site 2013 
RIF1 in DNA break repair pathway choice.   Daley, James M; Sung, Patrick R01ES007061 Mol Cell (2013 Mar 07) 23473603 Exiting the NIEHS site 2013 
Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα- ...   Xue, Xiaoyu; Raynard, Steven; Busygina, Valeria; Singh, Akhilesh K; Sung, Patrick R01ES007061 J Biol Chem (2013 May 17) 23543748 Exiting the NIEHS site 2013 
Roles of DNA helicases in the mediation and regulation of homologous recombination.   Daley, James M; Niu, Hengyao; Sung, Patrick R01ES007061 Adv Exp Med Biol (2013) 23161012 Exiting the NIEHS site 2013 
A two-dimensional ERK-AKT signaling code for an NGF-triggered cell-fate decision.   Chen, Jia-Yun; Lin, Jia-Ren; Cimprich, Karlene A; Meyer, Tobias R01ES016486, R01ES016486 Mol Cell (2012 Jan 27) 22206868 Exiting the NIEHS site 2012 
Finally, polyubiquitinated PCNA gets recognized.   Zeman, Michelle K; Cimprich, Karlene A R01ES016486, R01ES016486 Mol Cell (2012 Aug 10) 22883622 Exiting the NIEHS site 2012 
Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair.   Dunlop, Myun Hwa; Dray, Eloïse; Zhao, Weixing; San Filippo, Joseph; Tsai, Miaw-Sheue; Leung, S ... R01ES007061 J Biol Chem (2012 Apr 06) 22375013 Exiting the NIEHS site 2012 
Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiot ...   Busygina, Valeria; Saro, Dorina; Williams, Gareth; Leung, Wing-Kit; Say, Amanda F; Sehorn, Mic ... R01ES007061 J Biol Chem (2012 Jan 06) 22115747 Exiting the NIEHS site 2012 
Role of DNA polymerases in repeat-mediated genome instability.   Shah, Kartik A; Shishkin, Alexander A; Voineagu, Irina; Pavlov, Youri I; Shcherbakova, Polina V ... R01ES015869 Cell Rep (2012 Nov 29) 23142667 Exiting the NIEHS site 2012 
Activation of protein kinase Tel1 through recognition of protein-bound DNA ends.   Fukunaga, Kenzo; Kwon, Youngho; Sung, Patrick; Sugimoto, Katsunori R01ES007061 Mol Cell Biol (2011 May) 21402778 Exiting the NIEHS site 2011 
Analyses of the yeast Rad51 recombinase A265V mutant reveal different in vivo roles of Swi2-like fac ...   Chi, Peter; Kwon, YoungHo; Visnapuu, Mari-Liis; Lam, Isabel; Santa Maria, Sergio R; Zheng, Xiu ... R01ES007061 Nucleic Acids Res (2011 Aug) 21558173 Exiting the NIEHS site 2011 
Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylatio ...   Chen, Xuefeng; Niu, Hengyao; Chung, Woo-Hyun; Zhu, Zhu; Papusha, Alma; Shim, Eun Yong; Lee, S ... R01ES007061 Nat Struct Mol Biol (2011 Sep) 21841787 Exiting the NIEHS site 2011 
Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter.   Lu, Yuhong; Chu, Adrian; Turker, Mitchell S; Glazer, Peter M R01ES005775 Mol Cell Biol (2011 Aug) 21670155 Exiting the NIEHS site 2011 
Inhibition of hypoxia-induced miR-155 radiosensitizes hypoxic lung cancer cells.   Babar, Imran A; Czochor, Jennifer; Steinmetz, Allison; Weidhaas, Joanne B; Glazer, Peter M; Sla ... R01ES005775 Cancer Biol Ther (2011 Nov 15) 22027557 Exiting the NIEHS site 2011 
Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51 ...   Dray, Eloïse; Dunlop, Myun Hwa; Kauppi, Liisa; San Filippo, Joseph; Wiese, Claudia; Tsai, Miaw ... R01ES007061 Proc Natl Acad Sci U S A (2011 Mar 01) 21307306 Exiting the NIEHS site 2011 
Participation of translesion synthesis DNA polymerases in the maintenance of chromosome integrity in ...   Kochenova, O V; Soshkina, J V; Stepchenkova, E I; Inge-Vechtomov, S G; Shcherbakova, P V R01ES015869 Biochemistry (Mosc) (2011 Jan) 21568839 Exiting the NIEHS site 2011 
Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protei ...   Zheng, Xiao-Feng; Prakash, Rohit; Saro, Dorina; Longerich, Simonne; Niu, Hengyao; Sung, Patric ... R01ES007061 DNA Repair (Amst) (2011 Oct 10) 21880555 Exiting the NIEHS site 2011 
RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserve ...   Dunlop, Myun Hwa; Dray, Eloïse; Zhao, Weixing; Tsai, Miaw-Sheue; Wiese, Claudia; Schild, David ... R01ES007061 J Biol Chem (2011 Oct 28) 21903585 Exiting the NIEHS site 2011 
SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repa ...   Lin, Jia-Ren; Zeman, Michelle K; Chen, Jia-Yun; Yee, Muh-Ching; Cimprich, Karlene A R01ES016486, R01ES016486 Mol Cell (2011 Apr 22) 21396873 Exiting the NIEHS site 2011 
The non-canonical protein binding site at the monomer-monomer interface of yeast proliferating cell ...   Sharma, Neeru M; Kochenova, Olga V; Shcherbakova, Polina V R01ES015869 J Biol Chem (2011 Sep 23) 21799021 Exiting the NIEHS site 2011 
The Rad50 coiled-coil domain is indispensable for Mre11 complex functions.   Hohl, Marcel; Kwon, Youngho; Galván, Sandra Muñoz; Xue, Xiaoyu; Tous, Cristina; Aguilera, Andr ... R01ES007061 Nat Struct Mol Biol (2011 Sep 04) 21892167 Exiting the NIEHS site 2011 
A cancer-associated DNA polymerase delta variant modeled in yeast causes a catastrophic increase in ...   Daee, Danielle L; Mertz, Tony M; Shcherbakova, Polina V R01ES015869 Proc Natl Acad Sci U S A (2010 Jan 5) 19966286 Exiting the NIEHS site 2010 
Checkpoint recovery after DNA damage: a rolling stop for CDKs.   Duursma, Anja M; Cimprich, Karlene A R01ES016486, R01ES016486 EMBO Rep (2010 Jun) 20467435 Exiting the NIEHS site 2010 
Continued primer synthesis at stalled replication forks contributes to checkpoint activation.   Van, Christopher; Yan, Shan; Michael, W Matthew; Waga, Shou; Cimprich, Karlene A R01ES016486, R01ES016486 J Cell Biol (2010 Apr 19) 20385778 Exiting the NIEHS site 2010 
Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex.   Wang, Feng; Yang, Yuting; Singh, Thiyam Ramsing; Busygina, Valeria; Guo, Rong; Wan, Ke; Wang, ... R01ES007061 Structure (2010 Sep 08) 20826342 Exiting the NIEHS site 2010 
DNA polymerases at the eukaryotic fork-20 years later.   Pavlov, Youri I; Shcherbakova, Polina V R01ES015869 Mutat Res (2010 Mar 01) 19682465 Exiting the NIEHS site 2010 
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2.   Dray, Eloïse; Etchin, Julia; Wiese, Claudia; Saro, Dorina; Williams, Gareth J; Hammel, Michal; ... R01ES007061 Nat Struct Mol Biol (2010 Oct) 20871616 Exiting the NIEHS site 2010 
Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2 ...   Hegan, Denise Campisi; Lu, Yuhong; Stachelek, Gregory C; Crosby, Meredith E; Bindra, Ranjit S; ... R01ES005775 Proc Natl Acad Sci U S A (2010 Feb 02) 20133863 Exiting the NIEHS site 2010 
Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.   Niu, Hengyao; Chung, Woo-Hyun; Zhu, Zhu; Kwon, Youngho; Zhao, Weixing; Chi, Peter; Prakash, R ... R01ES007061 Nature (2010 Sep 2) 20811460 Exiting the NIEHS site 2010 
MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via ...   Singh, Thiyam Ramsing; Saro, Dorina; Ali, Abdullah Mahmood; Zheng, Xiao-Feng; Du, Chang-hu; Kil ... R01ES007061 Mol Cell (2010 Mar 26) 20347429 Exiting the NIEHS site 2010 
Participation of DNA polymerase zeta in replication of undamaged DNA in Saccharomyces cerevisiae.   Northam, Matthew R; Robinson, Heather A; Kochenova, Olga V; Shcherbakova, Polina V R01ES015869 Genetics (2010 Jan) 19841096 Exiting the NIEHS site 2010 
Potentiation of temozolomide cytotoxicity by inhibition of DNA polymerase beta is accentuated by BRC ...   Stachelek, Gregory C; Dalal, Shibani; Donigan, Katherine A; Campisi Hegan, Denise; Sweasy, Joan ... R01ES005775 Cancer Res (2010 Jan 01) 20028873 Exiting the NIEHS site 2010 
Promotion and regulation of homologous recombination by DNA helicases.   Colavito, Sierra; Prakash, Rohit; Sung, Patrick R01ES007061 Methods (2010 Jul) 20156560 Exiting the NIEHS site 2010 
Rad52 SUMOylation affects the efficiency of the DNA repair.   Altmannova, Veronika; Eckert-Boulet, Nadine; Arneric, Milica; Kolesar, Peter; Chaloupkova, Radk ... R01ES007061 Nucleic Acids Res (2010 Aug) 20371517 Exiting the NIEHS site 2010 
A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stabi ...   Paulsen, Renee D; Soni, Deena V; Wollman, Roy; Hahn, Angela T; Yee, Muh-Ching; Guan, Anna; Hes ... R01ES016486, R01ES016486 Mol Cell (2009 Jul 31) 19647519 Exiting the NIEHS site 2009 
Assay for human Rad51-mediated DNA displacement loop formation.   Raynard, Steven; Sung, Patrick R01ES007061 Cold Spring Harb Protoc (2009 Jan) 20147015 Exiting the NIEHS site 2009 
Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermedia ...   Matulova, Petra; Marini, Victoria; Burgess, Rebecca C; Sisakova, Alexandra; Kwon, Youngho; Roth ... R01ES007061 J Biol Chem (2009 Mar 20) 19129197 Exiting the NIEHS site 2009 
DNA damage tolerance: when it's OK to make mistakes.   Chang, Debbie J; Cimprich, Karlene A R01ES016486, R01ES016486 Nat Chem Biol (2009 Feb) 19148176 Exiting the NIEHS site 2009 
Emerging roles of microRNAs in the molecular responses to hypoxia.   Crosby, Meredith E; Devlin, Cecilia M; Glazer, Peter M; Calin, George A; Ivan, Mircea R01ES005775 Curr Pharm Des (2009) 19925433 Exiting the NIEHS site 2009 
Functional interactions of meiotic recombination factors Rdh54 and Dmc1.   Chi, Peter; Kwon, Youngho; Moses, Dana N; Seong, Changhyun; Sehorn, Michael G; Singh, Akhilesh ... R01ES007061 DNA Repair (Amst) (2009 Feb 1) 19028606 Exiting the NIEHS site 2009 
Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption.   Colavito, Sierra; Macris-Kiss, Margaret; Seong, Changhyun; Gleeson, Olive; Greene, Eric C; Klei ... R01ES007061 Nucleic Acids Res (2009 Nov) 19745052 Exiting the NIEHS site 2009 
HARPing on about the DNA damage response during replication.   Driscoll, Robert; Cimprich, Karlene A R01ES016486, R01ES016486 Genes Dev (2009 Oct 15) 19833762 Exiting the NIEHS site 2009 
Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo.   Burgess, Rebecca C; Lisby, Michael; Altmannova, Veronika; Krejci, Lumir; Sung, Patrick; Rothste ... R01ES007061 J Cell Biol (2009 Jun 15) 19506039 Exiting the NIEHS site 2009 
MicroRNA regulation of DNA repair gene expression in hypoxic stress.   Crosby, Meredith E; Kulshreshtha, Ritu; Ivan, Mircea; Glazer, Peter M R01ES005775 Cancer Res (2009 Feb 01) 19141645 Exiting the NIEHS site 2009 
Proliferating cell nuclear antigen uses two distinct modes to move along DNA.   Kochaniak, Anna B; Habuchi, Satoshi; Loparo, Joseph J; Chang, Debbie J; Cimprich, Karlene A; Wa ... R01ES016486, R01ES016486 J Biol Chem (2009 Jun 26) 19411704 Exiting the NIEHS site 2009 
Regulation of Rad51 recombinase presynaptic filament assembly via interactions with the Rad52 mediat ...   Seong, Changhyun; Colavito, Sierra; Kwon, Youngho; Sung, Patrick; Krejci, Lumir R01ES007061 J Biol Chem (2009 Sep 04) 19605344 Exiting the NIEHS site 2009 
Role of the Rad52 amino-terminal DNA binding activity in DNA strand capture in homologous recombinat ...   Shi, Idina; Hallwyl, Swee C L; Seong, Changhyun; Mortensen, Uffe; Rothstein, Rodney; Sung, Pat ... R01ES007061 J Biol Chem (2009 Nov 27) 19812039 Exiting the NIEHS site 2009 
Structural transitions within human Rad51 nucleoprotein filaments.   Robertson, Ragan B; Moses, Dana N; Kwon, YoungHo; Chan, Pamela; Chi, Peter; Klein, Hannah; Sun ... R01ES007061 Proc Natl Acad Sci U S A (2009 Aug 4) 19622740 Exiting the NIEHS site 2009 
Visualizing the disassembly of S. cerevisiae Rad51 nucleoprotein filaments.   Robertson, Ragan B; Moses, Dana N; Kwon, YoungHo; Chan, Pamela; Zhao, Weixing; Chi, Peter; Kle ... R01ES007061 J Mol Biol (2009 May 15) 19327367 Exiting the NIEHS site 2009 
Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic re ...   Prakash, Rohit; Satory, Dominik; Dray, Eloïse; Papusha, Almas; Scheller, Jürgen; Kramer, Wilfr ... R01ES007061 Genes Dev (2009 Jan 01) 19136626 Exiting the NIEHS site 2009 
ATP-dependent chromatin remodeling by the Saccharomyces cerevisiae homologous recombination factor R ...   Kwon, YoungHo; Seong, Changhyun; Chi, Peter; Greene, Eric C; Klein, Hannah; Sung, Patrick R01ES007061 J Biol Chem (2008 Apr 18) 18292093 Exiting the NIEHS site 2008 
ATR: an essential regulator of genome integrity.   Cimprich, Karlene A; Cortez, David R01ES016486, R01ES016486 Nat Rev Mol Cell Biol (2008 Aug) 18594563 Exiting the NIEHS site 2008 
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance a ...   Chan, Norman; Koritzinsky, Marianne; Zhao, Helen; Bindra, Ranjit; Glazer, Peter M; Powell, Sim ... R01ES005775 Cancer Res (2008 Jan 15) 18199558 Exiting the NIEHS site 2008 
Interaction with RPA is necessary for Rad52 repair center formation and for its mediator activity.   Plate, Iben; Hallwyl, Swee C L; Shi, Idina; Krejci, Lumir; Müller, Christian; Albertsen, Line; ... R01ES007061 J Biol Chem (2008 Oct 24) 18703507 Exiting the NIEHS site 2008 
Molecular anatomy of the recombination mediator function of Saccharomyces cerevisiae Rad52.   Seong, Changhyun; Sehorn, Michael G; Plate, Iben; Shi, Idina; Song, Binwei; Chi, Peter; Morten ... R01ES007061 J Biol Chem (2008 May 02) 18310075 Exiting the NIEHS site 2008 
Rad52 multimerization is important for its nuclear localization in Saccharomyces cerevisiae.   Plate, Iben; Albertsen, Line; Lisby, Michael; Hallwyl, Swee C L; Feng, Qi; Seong, Changhyun; R ... R01ES007061 DNA Repair (Amst) (2008 Jan 1) 17888746 Exiting the NIEHS site 2008 
Analyzing the ATR-mediated checkpoint using Xenopus egg extracts.   Lupardus, Patrick J; Van, Christopher; Cimprich, Karlene A R01ES016486, R01ES016486 Methods (2007 Feb) 17189864 Exiting the NIEHS site 2007 
Bipartite stimulatory action of the Hop2-Mnd1 complex on the Rad51 recombinase.   Chi, Peter; San Filippo, Joseph; Sehorn, Michael G; Petukhova, Galina V; Sung, Patrick R01ES007061 Genes Dev (2007 Jul 15) 17639080 Exiting the NIEHS site 2007 
Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max net ...   Bindra, Ranjit S; Glazer, Peter M R01ES005775 Cancer Lett (2007 Jul 8) 17275176 Exiting the NIEHS site 2007 
Lessons from 50 years of SOS DNA-damage-induced mutagenesis.   Schlacher, Katharina; Goodman, Myron F R01ES029680, R01ES029680 Nat Rev Mol Cell Biol (2007 07) 17551516 Exiting the NIEHS site 2007 
Probing ATR activation with model DNA templates.   Cimprich, Karlene A R01ES016486, R01ES016486 Cell Cycle (2007 Oct 01) 17700074 Exiting the NIEHS site 2007 
Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia.   Bindra, R S; Glazer, P M R01ES005775 Oncogene (2007 Mar 29) 17001309 Exiting the NIEHS site 2007 
Role of Dnl4-Lif1 in nonhomologous end-joining repair complex assembly and suppression of homologous ...   Zhang, Yu; Hefferin, Melissa L; Chen, Ling; Shim, Eun Yong; Tseng, Hui-Min; Kwon, Youngho; Sun ... R01ES007061 Nat Struct Mol Biol (2007 Jul) 17589524 Exiting the NIEHS site 2007 
The ATR pathway: fine-tuning the fork.   Paulsen, Renee D; Cimprich, Karlene A R01ES016486, R01ES016486 DNA Repair (Amst) (2007 Jul 01) 17531546 Exiting the NIEHS site 2007 
The structural determinants of checkpoint activation.   MacDougall, Christina A; Byun, Tony S; Van, Christopher; Yee, Muh-ching; Cimprich, Karlene A R01ES016486, R01ES016486 Genes Dev (2007 Apr 15) 17437996 Exiting the NIEHS site 2007 
Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites.   Bindra, Ranjit S; Glazer, Peter M R01ES005775 Cancer Biol Ther (2006 Oct) 17106239 Exiting the NIEHS site 2006 
CHK2-dependent phosphorylation of BRCA1 in hypoxia.   Gibson, Shannon L; Bindra, Ranjit S; Glazer, Peter M R01ES005775 Radiat Res (2006 Oct) 17007555 Exiting the NIEHS site 2006 
Differing patterns of genetic instability in mice deficient in the mismatch repair genes Pms2, Mlh1, ...   Hegan, Denise Campisi; Narayanan, Latha; Jirik, Frank R; Edelmann, Winfried; Liskay, R Michael; ... R01ES005775 Carcinogenesis (2006 Dec) 16728433 Exiting the NIEHS site 2006 
Monoubiquitination of proliferating cell nuclear antigen induced by stalled replication requires unc ...   Chang, Debbie J; Lupardus, Patrick J; Cimprich, Karlene A R01ES016486, R01ES016486 J Biol Chem (2006 Oct 27) 16959771 Exiting the NIEHS site 2006 
Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage toler ...   Gibson, Shannon L; Narayanan, Latha; Hegan, Denise Campisi; Buermeyer, Andrew B; Liskay, R Mich ... R01ES005775 Cancer Lett (2006 Dec 8) 16426742 Exiting the NIEHS site 2006 
RecA acts in trans to allow replication of damaged DNA by DNA polymerase V.   Schlacher, Katharina; Cox, Michael M; Woodgate, Roger; Goodman, Myron F R01ES029680, R01ES029680 Nature (2006 Aug 24) 16929290 Exiting the NIEHS site 2006 
Recombination mediator and Rad51 targeting activities of a human BRCA2 polypeptide.   San Filippo, Joseph; Chi, Peter; Sehorn, Michael G; Etchin, Julia; Krejci, Lumir; Sung, Patric ... R01ES007061 J Biol Chem (2006 Apr 28) 16513631 Exiting the NIEHS site 2006 
Roles of ATP binding and ATP hydrolysis in human Rad51 recombinase function.   Chi, Peter; Van Komen, Stephen; Sehorn, Michael G; Sigurdsson, Stefan; Sung, Patrick R01ES007061 DNA Repair (Amst) (2006 Mar 7) 16388992 Exiting the NIEHS site 2006 
Yeast recombination factor Rdh54 functionally interacts with the Rad51 recombinase and catalyzes Rad ...   Chi, Peter; Kwon, Youngho; Seong, Changhyun; Epshtein, Anastasiya; Lam, Isabel; Sung, Patrick; ... R01ES007061 J Biol Chem (2006 Sep 08) 16831867 Exiting the NIEHS site 2006 
Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair ...   Chen, Ling; Trujillo, Kelly M; Van Komen, Stephen; Roh, Dong Hyun; Krejci, Lumir; Lewis, L Kev ... R01ES007061 J Biol Chem (2005 Jan 28) 15546877 Exiting the NIEHS site 2005 
Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells.   Meng, Alice X; Jalali, Farid; Cuddihy, Andrew; Chan, Norman; Bindra, Ranjit S; Glazer, Peter M ... R01ES005775 Radiother Oncol (2005 Aug) 16026872 Exiting the NIEHS site 2005 
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.   Bindra, Ranjit S; Gibson, Shannon L; Meng, Alice; Westermark, Ulrica; Jasin, Maria; Pierce, An ... R01ES005775 Cancer Res (2005 Dec 15) 16357170 Exiting the NIEHS site 2005 
Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner.   Gibson, Shannon L; Bindra, Ranjit S; Glazer, Peter M R01ES005775 Cancer Res (2005 Dec 1) 16322218 Exiting the NIEHS site 2005 
Saccharomyces cerevisiae MPH1 gene, required for homologous recombination-mediated mutation avoidanc ...   Prakash, Rohit; Krejci, Lumir; Van Komen, Stephen; Anke Schürer, Kirsten; Kramer, Wilfried; Sun ... R01ES007061 J Biol Chem (2005 Mar 04) 15634678 Exiting the NIEHS site 2005 
Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced throug ...   Jensen, Ryan; Glazer, Peter M R01ES005775 Proc Natl Acad Sci U S A (2004 Apr 20) 15069205 Exiting the NIEHS site 2004 
Differential arrangements of conserved building blocks among homologs of the Rad50/Mre11 DNA repair ...   de Jager, Martijn; Trujillo, Kelly M; Sung, Patrick; Hopfner, Karl-Peter; Carney, James P; Tain ... R01ES007061 J Mol Biol (2004 Jun 11) 15165861 Exiting the NIEHS site 2004 
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells.   Bindra, Ranjit S; Schaffer, Paul J; Meng, Alice; Woo, Jennifer; Måseide, Kårstein; Roth, Matt ... R01ES005775 Mol Cell Biol (2004 Oct) 15367671 Exiting the NIEHS site 2004 
Meiotic recombination: an affair of two recombinases.   Sehorn, Michael G; Sung, Patrick R01ES007061 Cell Cycle (2004 Nov) 15547324 Exiting the NIEHS site 2004 
Multiple interactions with the Rad51 recombinase govern the homologous recombination function of Rad ...   Raschle, Markus; Van Komen, Stephen; Chi, Peter; Ellenberger, Tom; Sung, Patrick R01ES007061 J Biol Chem (2004 Dec 10) 15465810 Exiting the NIEHS site 2004 
Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52.   Motycka, Teresa A; Bessho, Tadayoshi; Post, Sean M; Sung, Patrick; Tomkinson, Alan E R01ES007061 J Biol Chem (2004 Apr 02) 14734547 Exiting the NIEHS site 2004 
Role of ATP hydrolysis in the antirecombinase function of Saccharomyces cerevisiae Srs2 protein.   Krejci, Lumir; Macris, Margaret; Li, Ying; Van Komen, Stephen; Villemain, Jana; Ellenberger, T ... R01ES007061 J Biol Chem (2004 May 28) 15047689 Exiting the NIEHS site 2004 
Role of the nuclease activity of Saccharomyces cerevisiae Mre11 in repair of DNA double-strand break ...   Lewis, L Kevin; Storici, Francesca; Van Komen, Stephen; Calero, Shanna; Sung, Patrick; Resnick, ... R01ES007061 Genetics (2004 Apr) 15126391 Exiting the NIEHS site 2004 
ATPase and DNA helicase activities of the Saccharomyces cerevisiae anti-recombinase Srs2.   Van Komen, Stephen; Reddy, Mothe Sreedhar; Krejci, Lumir; Klein, Hannah; Sung, Patrick R01ES007061 J Biol Chem (2003 Nov 07) 12966095 Exiting the NIEHS site 2003 
Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells.   Mihaylova, Valia T; Bindra, Ranjit S; Yuan, Jianling; Campisi, Denise; Narayanan, Latha; Jensen ... R01ES005775 Mol Cell Biol (2003 May) 12697826 Exiting the NIEHS site 2003 
Rad51 recombinase and recombination mediators.   Sung, Patrick; Krejci, Lumir; Van Komen, Stephen; Sehorn, Michael G R01ES007061 J Biol Chem (2003 Oct 31) 12912992 Exiting the NIEHS site 2003 
Yeast xrs2 binds DNA and helps target rad50 and mre11 to DNA ends.   Trujillo, Kelly M; Roh, Dong Hyun; Chen, Ling; Van Komen, Stephen; Tomkinson, Alan; Sung, Patr ... R01ES007061 J Biol Chem (2003 Dec 05) 14522986 Exiting the NIEHS site 2003 
Functional cross-talk among Rad51, Rad54, and replication protein A in heteroduplex DNA joint format ...   Van Komen, Stephen; Petukhova, Galina; Sigurdsson, Stefan; Sung, Patrick R01ES007061 J Biol Chem (2002 Nov 15) 12226081 Exiting the NIEHS site 2002 
Interaction with Rad51 is indispensable for recombination mediator function of Rad52.   Krejci, Lumir; Song, Binwei; Bussen, Wendy; Rothstein, Rodney; Mortensen, Uffe H; Sung, Patric ... R01ES007061 J Biol Chem (2002 Oct 18) 12171935 Exiting the NIEHS site 2002 
ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiat ...   Peretz, S; Jensen, R; Baserga, R; Glazer, P M R01ES005775 Proc Natl Acad Sci U S A (2001 Feb 13) 11172010 Exiting the NIEHS site 2001 
Basis for avid homologous DNA strand exchange by human Rad51 and RPA.   Sigurdsson, S; Trujillo, K; Song, B; Stratton, S; Sung, P R01ES007061 J Biol Chem (2001 Mar 23) 11124265 Exiting the NIEHS site 2001 
DNA pairing and strand exchange by the Escherichia coli RecA and yeast Rad51 proteins without ATP hy ...   Rice, K P; Eggler, A L; Sung, P; Cox, M M R01ES007061 J Biol Chem (2001 Oct 19) 11504729 Exiting the NIEHS site 2001 
DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex.   Trujillo, K M; Sung, P R01ES007061 J Biol Chem (2001 Sep 21) 11454871 Exiting the NIEHS site 2001 
Hypermutability to ionizing radiation in mismatch repair-deficient, Pms2 knockout mice.   Xu, X S; Narayanan, L; Dunklee, B; Liskay, R M; Glazer, P M R01ES005775 Cancer Res (2001 May 1) 11325851 Exiting the NIEHS site 2001 
Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange.   Sigurdsson, S; Van Komen, S; Bussen, W; Schild, D; Albala, J S; Sung, P R01ES007061 Genes Dev (2001 Dec 15) 11751636 Exiting the NIEHS site 2001 
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes.   Chen, L; Trujillo, K; Ramos, W; Sung, P; Tomkinson, A E R01ES007061 Mol Cell (2001 Nov) 11741545 Exiting the NIEHS site 2001 
Structure of the Rad50 x Mre11 DNA repair complex from Saccharomyces cerevisiae by electron microsco ...   Anderson, D E; Trujillo, K M; Sung, P; Erickson, H P R01ES007061 J Biol Chem (2001 Oct 05) 11470800 Exiting the NIEHS site 2001 
Functional interactions among yeast Rad51 recombinase, Rad52 mediator, and replication protein A in ...   Song, B; Sung, P R01ES007061 J Biol Chem (2000 May 26) 10748203 Exiting the NIEHS site 2000 
Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase.   Chen, L; Trujillo, K; Sung, P; Tomkinson, A E R01ES007061 J Biol Chem (2000 Aug 25) 10854421 Exiting the NIEHS site 2000 
Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways.   Zeng, M; Narayanan, L; Xu, X S; Prolla, T A; Liskay, R M; Glazer, P M R01ES005775 Cancer Res (2000 Sep 1) 10987303 Exiting the NIEHS site 2000 
Mutagenesis in PMS2- and MSH2-deficient mice indicates differential protection from transversions an ...   Andrew, S E; Xu, X S; Baross-Francis, A; Narayanan, L; Milhausen, K; Liskay, R M; Jirik, F R; ... R01ES005775 Carcinogenesis (2000 Jul) 10874005 Exiting the NIEHS site 2000 
Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1.   Petukhova, G; Sung, P; Klein, H R01ES007061 Genes Dev (2000 Sep 01) 10970884 Exiting the NIEHS site 2000 
Recombination factors of Saccharomyces cerevisiae.   Sung, P; Trujillo, K M; Van Komen, S R01ES007061 Mutat Res (2000 Jun 30) 10915877 Exiting the NIEHS site 2000 
Superhelicity-driven homologous DNA pairing by yeast recombination factors Rad51 and Rad54.   Van Komen, S; Petukhova, G; Sigurdsson, S; Stratton, S; Sung, P R01ES007061 Mol Cell (2000 Sep) 11030336 Exiting the NIEHS site 2000 
Different mutator phenotypes in Mlh1- versus Pms2-deficient mice.   Yao, X; Buermeyer, A B; Narayanan, L; Tran, D; Baker, S M; Prolla, T A; Glazer, P M; Liskay, ... R01ES005775 Proc Natl Acad Sci U S A (1999 Jun 08) 10359802 Exiting the NIEHS site 1999 
Single strand DNA binding and annealing activities in the yeast recombination factor Rad59.   Petukhova, G; Stratton, S A; Sung, P R01ES007061 J Biol Chem (1999 Nov 26) 10567339 Exiting the NIEHS site 1999 
The Tyr-265-to-Cys mutator mutant of DNA polymerase beta induces a mutator phenotype in mouse LN12 c ...   Clairmont, C A; Narayanan, L; Sun, K W; Glazer, P M; Sweasy, J B R01ES005775 Proc Natl Acad Sci U S A (1999 Aug 17) 10449735 Exiting the NIEHS site 1999 
Yeast Rad54 promotes Rad51-dependent homologous DNA pairing via ATP hydrolysis-driven change in DNA ...   Petukhova, G; Van Komen, S; Vergano, S; Klein, H; Sung, P R01ES007061 J Biol Chem (1999 Oct 08) 10506208 Exiting the NIEHS site 1999 
Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95 ...   Trujillo, K M; Yuan, S S; Lee, E Y; Sung, P R01ES007061 J Biol Chem (1998 Aug 21) 9705271 Exiting the NIEHS site 1998 
Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pm ...   Narayanan, L; Fritzell, J A; Baker, S M; Liskay, R M; Glazer, P M R01ES005775 Proc Natl Acad Sci U S A (1997 Apr 01) 9096356 Exiting the NIEHS site 1997 
Function of yeast Rad52 protein as a mediator between replication protein A and the Rad51 recombinas ...   Sung, P R01ES007061 J Biol Chem (1997 Nov 07) 9353267 Exiting the NIEHS site 1997 
Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local bre ...   Turner, B C; Haffty, B G; Narayanan, L; Yuan, J; Havre, P A; Gumbs, A A; Kaplan, L; Burgaud, ... R01ES005775 Cancer Res (1997 Aug 1) 9242428 Exiting the NIEHS site 1997 
Role of DNA mismatch repair in the cytotoxicity of ionizing radiation.   Fritzell, J A; Narayanan, L; Baker, S M; Bronner, C E; Andrew, S E; Prolla, T A; Bradley, A; ... R01ES005775 Cancer Res (1997 Nov 15) 9371516 Exiting the NIEHS site 1997 
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promo ...   Sung, P R01ES007061 Genes Dev (1997 May 01) 9159392 Exiting the NIEHS site 1997 
Dual requirement for the yeast MMS19 gene in DNA repair and RNA polymerase II transcription.   Lauder, S; Bankmann, M; Guzder, S N; Sung, P; Prakash, L; Prakash, S R01ES007061 Mol Cell Biol (1996 Dec) 8943333 Exiting the NIEHS site 1996 
Frequent spontaneous deletions at a shuttle vector locus in transgenic mice.   Leach, E G; Gunther, E J; Yeasky, T M; Gibson, L H; Yang-Feng, T L; Glazer, P M R01ES005775 Mutagenesis (1996 Jan) 8671715 Exiting the NIEHS site 1996 
Genetic instability induced by the tumor microenvironment.   Reynolds, T Y; Rockwell, S; Glazer, P M R01ES005775 Cancer Res (1996 Dec 15) 8971187 Exiting the NIEHS site 1996 
Mutagenesis by third-strand-directed psoralen adducts in repair-deficient human cells: high frequenc ...   Raha, M; Wang, G; Seidman, M M; Glazer, P M R01ES005775 Proc Natl Acad Sci U S A (1996 Apr 02) 8610147 Exiting the NIEHS site 1996 
Mutagenesis in mammalian cells induced by triple helix formation and transcription-coupled repair.   Wang, G; Seidman, M M; Glazer, P M R01ES005775 Science (1996 Feb 09) 8628995 Exiting the NIEHS site 1996 
Recombination induced by triple-helix-targeted DNA damage in mammalian cells.   Faruqi, A F; Seidman, M M; Segal, D J; Carroll, D; Glazer, P M R01ES005775 Mol Cell Biol (1996 Dec) 8943337 Exiting the NIEHS site 1996 
Targeted mutagenesis mediated by the triple helix formation.   Glazer, P M; Wang, G; Havre, P A; Gunther, E J R01ES005775 Methods Mol Biol (1996) 8849999 Exiting the NIEHS site 1996 
Tissue specificity of spontaneous point mutations in lambda supF transgenic mice.   Leach, E G; Narayanan, L; Havre, P A; Gunther, E J; Yeasky, T M; Glazer, P M R01ES005775 Environ Mol Mutagen (1996) 8991078 Exiting the NIEHS site 1996 
Yeast Rad51 recombinase mediates polar DNA strand exchange in the absence of ATP hydrolysis.   Sung, P; Stratton, S A R01ES007061 J Biol Chem (1996 Nov 08) 8910403 Exiting the NIEHS site 1996 
Altered repair of targeted psoralen photoadducts in the context of an oligonucleotide-mediated tripl ...   Wang, G; Glazer, P M R01ES005775 J Biol Chem (1995 Sep 22) 7673252 Exiting the NIEHS site 1995 
DNA strand exchange mediated by a RAD51-ssDNA nucleoprotein filament with polarity opposite to that ...   Sung, P; Robberson, D L R01ES007061 Cell (1995 Aug 11) 7634335 Exiting the NIEHS site 1995 
Frequent T:A-->G:C transversions in X-irradiated mouse cells.   Yuan, J; Yeasky, T M; Rhee, M C; Glazer, P M R01ES005775 Carcinogenesis (1995 Jan) 7834808 Exiting the NIEHS site 1995 
Induction of p53 in mouse cells decreases mutagenesis by UV radiation.   Yuan, J; Yeasky, T M; Havre, P A; Glazer, P M R01ES005775 Carcinogenesis (1995 Oct) 7586125 Exiting the NIEHS site 1995 
Mutagenesis by 8-methoxypsoralen and 5-methylangelicin photoadducts in mouse fibroblasts: mutations ...   Gunther, E J; Yeasky, T M; Gasparro, F P; Glazer, P M R01ES005775 Cancer Res (1995 Mar 15) 7882323 Exiting the NIEHS site 1995 
Targeted mutagenesis in mammalian cells mediated by intracellular triple helix formation.   Wang, G; Levy, D D; Seidman, M M; Glazer, P M R01ES005775 Mol Cell Biol (1995 Mar) 7862165 Exiting the NIEHS site 1995 
Site-specific targeting of psoralen photoadducts with a triple helix-forming oligonucleotide: charac ...   Gasparro, F P; Havre, P A; Olack, G A; Gunther, E J; Glazer, P M R01ES005775 Nucleic Acids Res (1994 Jul 25) 8052539 Exiting the NIEHS site 1994 
High efficiency, restriction-deficient in vitro packaging extracts for bacteriophage lambda DNA usin ...   Gunther, E J; Murray, N E; Glazer, P M R01ES005775 Nucleic Acids Res (1993 Aug 11) 8396240 Exiting the NIEHS site 1993 
Targeted mutagenesis of DNA using triple helix-forming oligonucleotides linked to psoralen.   Havre, P A; Gunther, E J; Gasparro, F P; Glazer, P M R01ES005775 Proc Natl Acad Sci U S A (1993 Aug 15) 8356097 Exiting the NIEHS site 1993 
Targeted mutagenesis of simian virus 40 DNA mediated by a triple helix-forming oligonucleotide.   Havre, P A; Glazer, P M R01ES005775 J Virol (1993 Dec) 8230456 Exiting the NIEHS site 1993 
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